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| | Ovarian Germ Cell Tumors |
 | | Unless a doctor is sure the cancer has spread from the ovaries to other parts of the body, surgery is required to determine the stage of cancer in an operation called a laparotomy. | | | Treatment given after the surgery to increase the chances of a cure is called adjuvant therapy. | | | When chemotherapy is placed directly in the spinal column, an organ, or a body cavity such as the abdomen, the drugs mainly affect cancer cells in those areas. |
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http://www.meb.uni-bonn.de/cancer.gov/CDR0000062967.html
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| | Extra-gonadal Germ Cell Tumors |
| | The association between primary germ cell tumors of the mediastinum (the space between the lung pleura that contains the heart and other chest viscera) and hematologic malignancies has been described by retrospective analysis of patients treated at individual clinical centers. | | | METHODS: Fourteen men (median age 33 years) with primary retroperitoneal germ cell tumours were treated by chemotherapy followed by surgical resection of the primary tumour and metastases via a thoracoabdominal extraperitoneal approach. | | | Nine patients were treated by complete surgical excision of the mass, and additional postoperative radiation therapy was given to two patients. |
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http://www.thedoctorsdoctor.com/diseases/gct_extragonadal.htm
(9288 words)
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| | Germ Cell Tumors |
| | A small sample of the tumor is removed either surgically, called an open biopsy, or using a needle, called a needle biopsy, to check whether the cells are benign or malignant. | | | The remaining 10 percent are extragonadal, which means they develop somewhere outside the gonads, usually the chest, lower back, and head. | | | Malignant tumors in the mediastinum, which is around midchest, near the lungs, can cause chest pain, breathing problems, cough, and fever. |
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http://www.hmc.psu.edu/childrens/healthinfo/g/germcell.htm
(1169 words)
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| | Ovarian Germ Cell Tumors |
| | Thus, adjuvant cisplatin, etoposide, and bleomycin have replaced radiation therapy except in the rare patient in whom chemotherapy is not considered appropriate. | | | Cisplatin-based chemotherapy has been used effectively for patients with recurrent dysgerminoma with and without adjuvant radiation therapy. | | | Although there is considerable experience with VAC (vincristine/dactinomycin/cyclophosphamide), especially when given in an adjuvant setting, combinations containing bleomycin, etoposide, and cisplatin (BEP) are more effective. |
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http://www.meb.uni-bonn.de/cancer.gov/CDR0000062935.html
(4032 words)
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| | Germ Cell Tumors (Brain) |
| | Germinomas are very sensitive to radiation therapy, and about 85 percent of patients are cured with radiation therapy alone. | | | Pineal region tumors cause increased pressure on the brain, with headache and vision problems. | | | Because these tumors are so rare, it is difficult to perform meaningful large-scale clinical trials except in the context of a national, multi-institutional study. |
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http://www.stjude.org/disease-summaries/0,2557,449_2160_5037,00.html
(425 words)
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| | eMedicine - Extragonadal Germ Cell Tumors : Article by Issam Makhoul, MD |
| | A recent alternative theory suggests that primary mediastinal presentations represent reverse migration of occult carcinoma in situ (CIS) lesions in the gonad; hence, they may be gonadal in origin. | | | Medicine is a constantly changing science and not all therapies are clearly established. | | | DeVita VT, Hellman S, Rosenberg SA, eds: Cancer, Principles and Practice of Oncology. |
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http://www.emedicine.com/med/topic759.htm
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| | National Cancer Institute - Childhood Extracranial Germ Cell Tumor Treatment |
| | Refer to the PDQ summary on Late Effects of Childhood Cancer Therapies for specific information about the incidence, type, and monitoring of late effects in childhood and adolescent cancer survivors. | | | Nichols CR, Heerema NA, Palmer C, et al.: Klinefelter's syndrome associated with mediastinal germ cell neoplasms. | | | Guidelines for the pediatric cancer center and role of such centers in diagnosis and treatment. |
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http://www.cancer.gov/cancerinfo/pdq/treatment/extracranial-germ-cell/healthprofessional
(1525 words)
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| | Germ Cell Tumors |
| | All medical information needs to be carefully reviewed with your health care provider. | | | DISCLAIMER: NOAH is an information guide only and cannot answer personal health-related or research questions. | | | Extragonadal Germ Cell Tumor: Treatment National Cancer Institute (also in Spanish) |
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http://www.noah-health.org/en/cancer/types/germ.html
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| | Germ cell cancer - MayoClinic.com |
| | Typically, these cancers respond very well to chemotherapy and radiation therapy. | | | The prognosis for germ cell cancers is generally favorable. | | | But this depends on several factors, including the exact type of germ cell cancer, where it originated and the extent to which it has spread. |
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http://www.mayoclinic.com/health/germ-cell-cancer/AN00831
(240 words)
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| | Germ Cell Tumors |
| | Staging determines if the cancer has spread from the ovaries to other parts of the body. | | | Stage I: Cancer is found only in one or both of the ovaries. | | | Once ovarian germ cell tumor has been found, surgery and staging is the first course of action. |
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http://www.acor.org/ped-onc/diseases/germcell.html
(812 words)
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| | NEJM -- Testicular Germ-Cell Cancer |
| | Kesler, K. A., Wilson, J. L., Cosgrove, J. A., Brooks, J. A., Messiha, A., Fineberg, N. S., Einhorn, L. H., Brown, J. Surgical salvage therapy for malignant intrathoracic metastases from nonseminomatous germ cell cancer of testicular origin: Analysis of a single-institution experience. | | | Mazumdar, M., Bajorin, D.F., Bacik, J., Higgins, G., Motzer, R.J., Bosl, G.J. Predicting Outcome to Chemotherapy in Patients With Germ Cell Tumors: The Value of the Rate of Decline of Human Chorionic Gonadotrophin and Alpha-Fetoprotein During Therapy. | | | Kondagunta, G. V., Bacik, J., Donadio, A., Bajorin, D., Marion, S., Sheinfeld, J., Bosl, G. J., Motzer, R. Combination of Paclitaxel, Ifosfamide, and Cisplatin Is an Effective Second-Line Therapy for Patients With Relapsed Testicular Germ Cell Tumors. |
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http://content.nejm.org/cgi/content/short/337/4/242
(1864 words)
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| | Germ Cell Tumors - Lucile Packard Children's Hospital |
| | The symptoms of germ cell tumors may resemble other conditions or medical problems. | | | Germ cell tumors account for 16 percent of all cancers diagnosed in adolescents between the ages of 15 and 19 years old, and nearly 4 percent of cancers diagnosed in children younger than 15 years old. | | | The diagnosis, treatment, and prognosis are based on the most malignant of the cells present and the majority type of cells that are present. |
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http://www.lpch.org/DiseaseHealthInfo/HealthLibrary/oncology/gct.html
(1375 words)
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| | Germ Cell Tumors |
| | The development of chemotherapy has revolutionized the treatment of germ cell tumors and now almost 90 percent of the germ cell ovarian cancers are curable. | | | Unlike epithelial ovarian cancer, the germ cell tumors usually occurs in much younger age groups, usually in teenagers and women who are in their early twenties. | | | Germ cells are the cells from which the future ova are developed in a woman. |
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http://ccc.domaindlx.com/ovarian/germ-cell-tumors.html
(116 words)
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| | Germ cell definition - Medical Dictionary definitions of popular medical terms |
| | Adult Brain Tumors - Explains adult brain tumors (diseases in which malignant cancer cells grow in the brain) includes symptoms, diagnosis, and brain cancer treatment. | | | Germ cell definition - Medical Dictionary definitions of popular medical terms | | | Please consult your healthcare provider before beginning any course of supplementation or treatment. |
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http://www.medterms.com/script/main/art.asp?articlekey=8591
(258 words)
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| | OVARIAN CANCER: Diagnosis and Treatment |
| | The spread of cancer beyond its tissue of origin is called metastasis. | | | Germ cell neoplasms are thought to be derived from primitive germ cells of the embryonic gonad. | | | CancerNet: Treatment of Ovarian Germ Cell Tumor (for a more detailed version, see the guide for the health professional) |
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http://ovariancancer.jhmi.edu/germcell.cfm
(649 words)
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| | Extragonadal Germ Cell Cancer |
| | Occasionally, however, germ cell tumors develop elsewhere in the body without any evidence of cancer in the testes. | | | Typically, seminomas (and germinomas) have a more favorable outcome than the other types of germ cell cancer. | | | Extragonadal tumors arise when these cells become cancerous. |
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http://tcrc.acor.org/egc.html
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| | Germ Cell Tumours in Children and Young Adults |
| | However, they can also develop in other parts of the body such as the sacrococcygeal region, brain, abdomen and other sites - this may occur when some of the germ cells in the embryo did not migrate properly. | | | For information on germ cell tumours of the brain see the section on brain tumours. | | | Germ cell tumours occur where these cells become cancerous. |
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http://www.cancerindex.org/ccw/guide2u.htm
(355 words)
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| | Germ cell - definition of Germ cell in Encyclopedia |
| | The diploid somatic cells of an individual will contain one copy of the chromosome set from the sperm and one copy of the chromosome set from the egg—that is, the cells of the offspring will have genes expressing characteristics of both the "father" and the "mother". | | | Gametes—also known as sex cells, germ cells, or spores—are the specialized cells that come together during fertilization (conception) in organisms that reproduce sexually. | | | Gametes from a mature diploid individual will be produced in the gonadal tissue through meiosis—a process of cellular division that reduces the number of sets of chromosomes from two to one (i.e., produces haploid gametes). |
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http://encyclopedia.laborlawtalk.com/Germ_cell
(411 words)
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| | Germ Cell Tumours - Genetics |
| | Disclaimer: This site is for educational purposes only; it can not be used in diagnosis or treatment. | | | DNA ploidy analysis of pediatric germ cell tumors. | | | Cytogenetic analysis of childhood endodermal sinus tumors: a Pediatric Oncology Group study. |
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http://www.cancerindex.org/geneweb/X2207.htm
(130 words)
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| | Germ Cell Tumors |
| | This group of tumors arise from sex cells and are related to various tumors of the sex organs. | | | These tumors tend to occur in young people, most are seen in patients under thirty years of age. | | | The most common tumor in this group is the germinoma. |
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http://www.cinn.org/ibsc/braintumor/diagnoses/germcelltumors.html
(330 words)
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| | The Germantown Cell Goup |
| | Formed in the early first quarter of 1998, a small band of members from the Chinese Community Church who all lived in the Germantown/Gaithersburg area were asked if they would like a cell group in that area. | | | I was hesitant at first because one of my brothers attended the group and I didn't know how that would work out. | | | However, all the other study groups that I attended close by never really clicked with me. Why I don't know but God led me to the Germantown Cell Group. |
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http://www.glue.umd.edu/~shyeah/CELL
(338 words)
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| | germ cell |
| | the sexual reproductive cell at any stage from the primordial cell to the mature gamete. |
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http://www.infoplease.com/dictionary/germ+cell
(32 words)
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| | definition of germ cell |
| | A cell, of either sex, directly concerned in the production of a new organism. | | | Cell, Concerned, Directly, Either, New, Organism, Production, Sex | | | Cell, Concerned, Directly, Either, In, New, Of, Organism, Production, Sex, The |
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http://www.brainydictionary.com/words/ge/germcell168856.html
(58 words)
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| | Developmental Cell Online |
| | The distinct activities of these proteins’ divergent extracellular domains suggest that IFITMs are cell adhesion factors whose specificity controls PGC migration. | | | View the Annotated Version of the Table of Contents with contextual explanations of the articles in the issue. | | | show that proteins of the interferon-induced transmembrane (IFITM or fragilis) family play a variety of roles in mammalian primordial germ cell (PGC) guidance; ITIFM1 expression in other cells repels PGCs, and this repulsion is required for PGCs to initiate emigration from the mesoderm to the gut. |
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http://www.developmentalcell.com
(381 words)
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| | Germ Cell Migration |
| | The primordial germ cells multiply in the upper reaches of the yolk sac and migrate to the gonad, a mesodermal structure which forms near the embryonic kidneys. | | | If the primordial germ cells are XY containing, they proliferate in the medulla or core of the gonad. | | | the reproductive component is derived from endodermal primordial germ cells |
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http://www.people.virginia.edu/~rjh9u/gondev.html
(87 words)
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