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Topic: Zidovudine



  
 zidovudine - Hutchinson encyclopedia article about zidovudine
Long-term affects of zidovudine on the babies' health remain to be determined.
Blood transfusions are often necessary, and the drug must be withdrawn if bone-marrow function is severely affected.
A US trial in 1994 showed that the drug does provide some protection to babies born to HIV-positive mothers.
http://encyclopedia.farlex.com/zidovudine   (197 words)

  
 Safety and tolerability of Zidovudine
The indication for Zidovudine in these study subjects was therapy of HIV infection and not MTCT prevention.
The bulk of the literature on clinical tolerability of Zidovudine originates from studies in industrialised countries where the experience in its therapeutic use is much broader.
Zidovudine, for the indication of prevention of mother to child transmission (MTCT) of HIV infection, is included in the 1998 World Health Organisation's Model List of Essential Drugs.
http://www.who.int/reproductive-health/docs/zidovudine.htm   (2423 words)

  
 Zidovudine (Retrovir, azidothymidine, AZT)
Zidovudine should be considered in choosing therapy for individuals experiencing viral recurrence on prior regimens, but resistance testing may be helpful in assessing the utility of zidovudine in the individual situation.
Whether zidovudine or stavudine is preferable in initial versus subsequent therapy is not known.
In addition, the combination of zidovudine + lamivudine or emtricitabine is recommended as a nucleoside backbone of choice for use in combination therapy.
http://hivinsite.ucsf.edu/InSite.jsp?page=ar-drugs&doc=ar-01-01   (1185 words)

  
 HIV & AIDS - AZT, Zidovudine, Retrovir - Product Information
The zidovudine cerebrospinal fluid (CSF)/plasma concentration ratio was determined in 39 patients receiving chronic therapy with Retrovir.
Microbiology: The relationship between in vitro susceptibility of HIV to zidovudine and the inhibition of HIV replication in humans or clinical response to therapy has not been established.
Methadone: In a pharmacokinetic study of nine HIV-positive patients receiving methadone-maintenance (30 to 90 mg daily) concurrent with 200 mg of Retrovir every 4 hours, no changes were observed in the pharmacokinetics of methadone upon initiation of therapy with Retrovir and after 14 days of treatment with Retrovir.
http://www.virusmyth.net/aids/data/pdr-azt.htm   (9344 words)

  
 AEGiS-RITA!: NRTI: ZIDOVUDINE (Retrovir) - March 2000
Zidovudine therapy is the current standard in preventing vertical transmission (mother to child) of HIV.
Special care should be taken when administering the drug to patients with advanced HIV disease or other conditions characterized by anemia or neutropenia.
In a study of pregnant women, ACTG 076, the estimated risk of mother-to-child transmission of HIV was less than 8% in zidovudine-treated infants (antenatal, perinatal, and neonatal drug administration) versus almost 25% in the placebo group.
http://www.aegis.com/pubs/rita/2000/RI000305.html   (833 words)

  
 AEGiS-RITA!: CLINICAL ALERT: Abbreviated zidovudine (Retrovir) regimens & perinatal transmission - January 1999
These cases were significant because zidovudine (Retrovir) was given not in the manner prescribed by results of previous clinical trials, but rather in shorter abbreviated courses.
Forms were sent to the treating physician or head of the clinic to verify the information contained in the requisition forms.
Pediatric AIDS Clinical Trials Group (PACTG) Protocol 076 in 1994 established a standard for the treatment for prevention of transmission of HIV from mother to infant.
http://www.aegis.com/pubs/rita/1999/RI990106.html   (1759 words)

  
 Zidovudine (AZT)
In a large case—control study from the USA of HIV-infected patients, no association was found between the incidence of non-Hodgkin lymphoma and therapeutic use of zidovudine.
No difference in the incidence of non-Hodgkin lymphoma relative to that in the general population was seen before and after introduction of zidovudine therapy.
There is inadequate evidence in humans for the carcinogenicity of zidovudine.
http://monographs.iarc.fr/htdocs/monographs/vol76/zidovudine.html   (841 words)

  
 Apo-Zidovudine
Therefore, it is especially important that you discuss with your child's doctor the good that this medicine may do as well as the risks of using it.
Zidovudine will not keep you from spreading HIV to other people.
This medicine also is used to help prevent pregnant women who have HIV from passing the virus to their babies during pregnancy and at birth.
http://www.healthtouch.com/bin/EContent_HT/drugShowLfts.asp?fname=usp0417.htm&title=Apo-Zidovudine&cid=l   (2010 words)

  
 MedlinePlus Drug Information: Zidovudine Oral
Talk to your doctor about the possible risks of using this drug for your condition.
tell your doctor and pharmacist if you are allergic to zidovudine or any other drugs.
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a687007.html   (732 words)

  
 Radioimmunoassay for monitoring zidovudine in dried blood spot specimens -- Mei et al. 44 (2): 281 -- Clinical Chemistry
(18) for the clinical monitoring of zidovudine therapy among
The pharmacokinetics and safety of zidovudine in the third trimester of pregnancy for women infected with human immunodeficiency virus and their infants: Phase I Acquired Immunodeficiency Syndrome Clinical Trials Group study (protocol 082).
for zidovudine therapy, and were tested anonymously for the
http://www.clinchem.org/cgi/content/full/44/2/281   (3193 words)

  
 Zidovudine Resistance and HIV-1 Disease Progression during Antiretroviral Therapy -- D'Aquila et al. 122 (6): 401 -- ...
to zidovudine during therapy [1], and the syncytium-inducing
the duration of zidovudine therapy before the study [16].
zidovudine and have switched therapy from zidovudine to didanosine
http://www.annals.org/cgi/content/full/122/6/401   (5413 words)

  
 The Effect of the Interaction of Acyclovir with Zidovudine on Progression to AIDS and Survival: Analysis of Data in the ...
The Effect of the Interaction of Acyclovir with Zidovudine on Progression to AIDS and Survival: Analysis of Data in the Multicenter AIDS Cohort Study -- Stein et al.
The Effect of the Interaction of Acyclovir with Zidovudine on Progression to AIDS and Survival: Analysis of Data in the Multicenter AIDS Cohort Study
the zidovudine and combination therapy arms became nonsignificant.
http://www.annals.org/cgi/content/full/121/2/100   (6105 words)

  
 National Institute of Pharmaceutical Education & Research, INDIA
Thomas SN, de Paepe A and Panchagnula R. Effect of L-menthol and 1, 8 cineole on skin permeation of zidovudine, on phase behavior and molecular organization of SC lipids.
Thomas NS and Panchagnula R. Transdermal delivery of zidovudine: effect of vehicles on permeation across rat skin and their mechanism of action.
Dunge A, Chakraborti AK and Singh S. Mechanistic explanation to the variable degradation behaviour of stavudine and zidovudine under hydrolytic, oxidative and photolytic conditions.
http://www.niper.nic.in/pub.htm   (8393 words)

  
 Tenofovir, Lamivudine and Zidovudine Combination Therapy Results in Surprisingly Low Rate of Treatment Failure
To evaluate this, researchers in Germany and Spain collected data retrospectively from all consecutive patients who were ever prescribed antiretroviral therapy consisting of tenofovir (245 mg once a day) and lamivudine plus zidovudine (150/300 mg twice a day co-formulated as Combivir) in each of the four participating HIV centers.
All patients who showed a virological failure on tenofovir, lamivudine and zidovudine were analyzed in more detail.
The authors conclude, “Taken together, our preliminary data indicate that triple NRTI regimens including zidovudine and tenofovir may be more effective than other triple NRTI combinations, as reported previously.
http://www.hivandhepatitis.com/recent/virologic/011405_a.html   (1048 words)

  
 abacavir-lamivudine-zidovudine (oral) - SJMMC, Ann Arbor, Michigan
Abacavir-lamivudine-zidovudine (Trizivir) is not a cure for HIV or AIDS, and you can still transmit the virus to others during treatment with this medication.
Trizivir tablets are a combination of three medicines: abacavir (Ziagen), lamivudine (Epivir), and zidovudine (Retrovir).
Abacavir-lamivudine-zidovudine (Trizivir) does not cure HIV or AIDS and you can still transmit the virus to others during therapy with this medication.
http://www.sjmercyhealth.org/112318.cfm   (2006 words)

  
 MedlinePlus Drug Information: Lamivudine and Zidovudine
Lamivudine and zidovudine does not prevent the spread of HIV to other people.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Your doctor will order certain lab tests to check your body's response to lamivudine and zidovudine.
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601066.html   (953 words)

  
 Retrovir (zidovudine, AZT) - Complete Drug Summary
Increased Adipocyte Apoptosis in Lipoatrophy Improves Within 48 Weeks of Switching Patient Therapy from Stavudine to Abacavir or Zidovudine
Therapeutic Drug Monitoring of the HIV/AIDS Drugs Abacavir, Zidovudine, Efavirenz, Nevirapine, Indinavir, Lopinavir, and Nelfinavir
Short-Course Zidovudine Does Not Adversely Affect Maternal HIV Status
http://www.hivandhepatitis.com/hiv_and_aids/retrovir_1.html   (684 words)

  
 The Body Pro: Zidovudine (AZT, Retrovir)
When people who had developed lipoatrohpy while taking d4T (stavudine, Zerit) switched to abacavir (Ziagen) or AZT (zidovudine, Retrovir), their condition improved.
Improvement in Lipoatrophy Associated with Highly Active Antiretroviral Therapy in Human Immunodeficiency Virus-Infected Patients Switched from Stavudine to Abacavir or Zidovudine: The Results of the TARHEEL Study — January 15, 2004
The Body Pro covers the 6th International Congress on Drug Therapy in HIV Infection
http://www.thebodypro.com/treat/azt.html   (785 words)

  
 zidovudine - HIV: health and medical information about HIV and AIDS
zidovudine - HIV: health and medical information about HIV and AIDS
MedicineNet Home > Medications A-Z List > HIV Home Page > zidovudine
DRUG CLASS AND MECHANISM: Zidovudine is an oral and injectable medication that is used for the treatment of infections with the human immunodeficiency virus (HIV).
http://www.medicinenet.com/zidovudine/article.htm   (718 words)

  
 Simple FactSheet: Lamivudine/zidovudine (Combivir)
This has led to a recommendation that HIV-positive pregnant women be counseled about the potential benefits of zidovudine in preventing the transmission of HIV to their child.
Symptoms of dementia can be forgetfulness and personality changes.
The treatment of Hepatitis B will likely require using combination therapy.
http://www.atdn.org/simple/combi.html   (960 words)

  
 HIV Medicine 2005 Zidovudine
The editors and the authors of HIV Medicine might agree - under certain conditions - to remove the copyright on their book for all languages except English and German.
Six-year follow-up of HIV-1-infected adults in a clinical trial of antiretroviral therapy with indinavir, zidovudine, and lamivudine.
Treatment with indinavir, zidovudine, and lamivudine in adults with HIV infection and prior antiretroviral therapy.
http://www.hivmedicine.com/textbook/drugs/zidovu.htm   (687 words)

  
 Retrovir brand zidovudine (AZT): a complete guide from AIDSmeds.com
AZT Treatment Has Reduced Mother to Infant HIV Transmission in the US by 67 Percent (8/12/99)
Short-course zidovudine monotherapy does not adversely affect maternal health (3/14/03)
Zidovudine before stavudine may benefit HIV patients more than reverse sequence (2/14/01)
http://www.aidsmeds.com/drugs/Retrovir.htm   (1862 words)

  
 Zidovudine - Wikipedia, the free encyclopedia
ZIDOVUDINE (AZT) - ORAL (Retrovir) side effects, medical uses, and drug interactions.
Zidovudine was the first drug approved for the treatment of AIDS and HIV infection.
Zidovudine (INN) or azidothymidine (AZT) is an antiretroviral drug, the first one approved for treatment of HIV.
http://en.wikipedia.org/wiki/Zidovudine   (1362 words)

  
 NEJM -- Absence of Cardiac Toxicity of Zidovudine in Infants
Conclusions Zidovudine was not associated with acute or chronic
to zidovudine (35.4 percent) and those exposed to the drug (35.3
exposure) and 58 HIV-infected infants (12 with zidovudine exposure).
http://content.nejm.org/cgi/content/short/343/11/759   (643 words)

  
 Simple FactSheet: zidovudine (AZT, Retrovir)
Retrovir is an anti-HIV treatment in a class of drugs called nucleoside reverse transcriptase inhibitors (NRTIs).
Zidovudine, trade name Retrovir (also known as AZT or ZDV) was the first drug approved for the treatment of HIV.
Glaxo-Wellcome, who make zidovudine (AZT, Retrovir), have an assistance program to help people having difficulty affording the drug.
http://www.atdn.org/simple/zido.html   (652 words)

  
 ZIDOVUDINE - AZT, ZDV a Commonly Used Medication
ZIDOVUDINE - AZT, ZDV a Commonly Used Medication
Acetominophen, probenecid, cimetidine, indomethacin, lorazepam, or aspirin may inhibit excretion and contribute to toxicity.
Treatment of HIV infection when CDC count is < 500/mm3 or symptomatic.
http://www.hivdent.org/drugs/ZIDOVUDINE.htm   (176 words)

  
 Drug Search - Medical Dictionary Search Engines
USP DI - Abacavir, Lamivudine, and Zidovudine (Systemic)
http://www.medical-dictionary-search-engines.com/drug   (752 words)

  
 AIDS - Adoption Encyclopedia
However, if the infected mother is treated with medication such as zidovudine (AZT) during pregnancy, the transmission rate is slashed by as much as two-thirds.
This means that instead of 30-50% of mothers with HIV/AIDS transmitting the virus to their newborns, treatment can decrease transmission to less than an 8% risk.
Children can contract HIV/AIDS in utero from an infected mother and can also contract the disease after birth through the mother's breast milk.
http://encyclopedia.adoption.com/entry/AIDS/34/1.html   (1771 words)

  
 AZT (Retrovir) The New Mexico AIDS InfoNet
AZT was the first drug approved for the treatment of HIV.
AZT is also known as azido-deoxythymidine, zidovudine or ZDV.
Generic versions made by Aurobindo, Ranbaxy and Roxane were approved in 2005.
http://www.aidsinfonet.org/articles.php?articleID=411   (742 words)

  
 HIV & AIDS - AZT, Retrovir ®, zidovudine, azidothymidine, Glaxo Wellcome SmithKline Beecham
Wear suitable protective clothing." Note the skull and bones on the label; the warning for a deathly poison (Bottle contains only 100 mg, humans are prescribed 300 to 1500 mg a day).
Brian Deer, 'Revealed: Fatal flaws of drug that gave hope'
HIV & AIDS - AZT, Retrovir ®, zidovudine, azidothymidine, Glaxo Wellcome SmithKline Beecham
http://www.virusmyth.net/aids/index/azt.htm   (540 words)

  
 Zidovudine
Zidovudine 200 mg PO tid ($279/month) OR Zidovudine 300 mg PO bid
http://www.fpnotebook.com/HIV66.htm   (138 words)

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