Wilms tumor-aniridia - Medicow
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Topic: Wilms tumor-aniridia


  
 www.patientcenters.com -- Childhood Cancer Center -- Wilms Tumor
The decision to use radiation therapy to treat a child with Wilms is based largely on the stage and histology of the tumor.
Due to improvements in surgical techniques, drug therapies, and radiation, 85 to 90 percent of children with Wilms tumor who receive state-of-the-art treatment are cured.
Once Wilms tumor has been diagnosed, surgery and/or more tests are done to determine if the cancer has spread to other parts of the body.
http://www.patientcenters.com/childcancer/news/wilms_tumor.html   (3309 words)

  
 Sloan-Kettering - Wilms' Tumor
Stage IV tumors with favorable or unfavorable histology are treated with a combination of surgery, radiation therapy, and chemotherapy.
Stage II tumors with unfavorable histology usually require surgery followed by radiation therapy and chemotherapy.
Once the tumor has been staged, your child's doctor will create a treatment plan to most effectively treat the disease.
http://www.mskcc.org/mskcc/html/3080.cfm   (1178 words)

  
 Wilms Tumor
Tumors that are difficult to remove or bilateral tumors are almost always treated with chemotherapy first to make subsequent surgery easier.
Laboratory studies are trying to identify tumors that are more likely to be resistant to therapy.
Treatment involves a combination of therapies that include surgery, chemotherapy, and, in advanced cases, radiation therapy. With this approach, cure rates are now 85-90 percent.
http://www.stjude.org/disease-summaries/0,2557,449_2167_2997,00.html   (767 words)

  
 MedlinePlus Medical Encyclopedia: Wilms' tumor
Children with a localized tumor have a 90% cure rate when treated with surgery and chemotherapy; or with surgery, radiation, and chemotherapy combined.
Radiation therapy and chemotherapy will often be started after surgery, depending on the stage of the tumor.
Special emphasis is placed on the history and physical exam -- looking for a family history of cancer and for associated birth defects in the child.
http://www.nlm.nih.gov/medlineplus/ency/article/001575.htm   (676 words)

  
 Wilms' tumor
These therapies are called adjuvant therapies, and this type of combination therapy has been shown to substantially improve outcome in patients with Wilms' tumor.
All of these patients receive abdominal radiation therapy and lung radiation therapy if the tumor has spread to the lungs.
These patients usually receive abdominal radiation therapy and lung radiation therapy if the tumor has spread to the lungs.
http://www.lifesteps.com/gm/Atoz/ency/wilms_tumor.jsp   (1749 words)

  
 Wilms' tumor
Because advances in treating children with Wilms' tumor have come through research, you may be asked to consider letting your child participate in a clinical trial, a carefully planned study to evaluate the benefits and risks of experimental treatments.
Improved imaging techniques help doctors to determine the extent of the cancer in Wilms' tumor and to plan treatment.
You may feel a mass in your child's abdomen during bathing or dressing, or your child's doctor may detect it during a routine physical examination.
http://www.cnn.com/HEALTH/library/DS/00436.html   (2378 words)

  
 eMedicine - WAGR Syndrome : Article by Steven K Bergstrom, MD
However, if a Wilms tumor develops, a multidisciplinary approach is required prior to surgery.
He or she can consult with the family regarding the likelihood of their having other affected offspring, and the geneticist can consult with patients regarding the risks to their offspring.
CT of the chest and abdomen may provide further information about the location and stage of the tumor.
http://www.emedicine.com/ped/topic2423.htm   (2625 words)

  
 Wilms' Tumor - Children's Hospital Boston
Chemotherapy may be used alone for some types of cancer or in conjunction with other therapy such as radiation or surgery.
This technique is most sensitive to determine whether a clot of the tumor extends from the kidney vein through the vena cava towards the heart.
pain in the abdomen from pressure on other organs near the tumor
http://www.childrenshospital.org/az/Site1808/mainpageS1808P0.html   (2109 words)

  
 Wilms' Tumor - DrGreene.com
Her chest X-ray showed that her lungs were filled with cancer and causing her to cough.
This is a situation where good doctors who primarily take care of adults with cancer or good pediatricians who don't primarily take care of cancer are not good enough.
The treatment involves removing the tumor surgically and giving chemotherapy.
http://www.drgreene.com/21_622.html   (1148 words)

  
 Brusa-Torricelli syndrome (www.whonamedit.com)
The condition is autosomal dominant with inconsistent phenotypic expression.
We thank Kelly Trout of the International WAGR Syndrome Association for for information submitted.
The association of aniridia and Wilms tumor is now well documented and more than 50 patients have been reported.
http://www.whonamedit.com/synd.cfm/2404.html   (242 words)

  
 Wilms' Tumor
External radiation therapy – radiation directed at the tumor from a source outside the body
Internal radiation therapy – radioactive materials placed into the body near the cancer cells
Wilms' tumors may grow large without causing any pain or other symptoms.
http://www.stjohn.org/HealthInfoLib/HGArticle.aspx?ArticleID=22835   (882 words)

  
 Renal Failure in the Denys-Drash and Wilms' Tumor-Aniridia Syndromes -- Breslow et al. 60 (15): 4030 -- Cancer Research
The observation time for each subject was the elapsed
patients with the aniridia syndrome were treated surgically for
and 10 of 46 patients with the Wilms’ tumor aniridia syndrome developed
http://cancerres.aacrjournals.org/cgi/content/full/60/15/4030   (2805 words)

  
 Wilms' tumor - Wikipedia, the free encyclopedia
The stroma may include striated muscle, cartilage, bone, fat tissue, fibrous tissue.
- The tumor is not ruptured or biopsied (open or needle) prior to removal.
Stage IV (10% of patients) Stage IV Wilms’ tumor is defined as the presence of hematogenous metastases (lung, liver, bone, or brain), or lymph node metastases outside the abdomenopelvic region.
http://en.wikipedia.org/wiki/Wilms'_tumor   (738 words)

  
 [No title]
The term WAGR syndrome defines the association of Wilms tumor, aniridia, genitourinary dysplasia and mental retardation.
The aniridia type 2 is a bilateral developmental disorder of the eye, characterized by the complete or partial aplasia or dysplasia of the iris and optic nerve hypoplasia, leading to vision impairment.
Renal failure in the Denys-Drash and Wilms' tumor-aniridia syndromes CANCER RESEARCH 2000 Aug 1; 60(15): 4030-2).
http://malattierare.pediatria.unipd.it/pubblicaMR/mr_dx_ing.asp?mr=365   (610 words)

  
 WAGR Syndrome
A combination of two or more of these conditions must be present for an individual to be diagnosed with WAGR Syndrome.
The acronym stands for (W)ilms' Tumor, the most common form of kidney cancer in children; (A)niridia, partial or complete absence of the colored region of the eye(s) (iris or irides); (G)onadoblastoma, cancer of the cells that form the testes in males or the ovaries in females (gonads); and Mental (R)etardation.
The clinical picture varies, depending upon the combination of associated abnormalities.
http://my.webmd.com/hw/health_guide_atoz/nord1014.asp   (507 words)

  
 Wilms tumor of the Kidney
•The tumor may arise as a result of failure of blastemal tissue to differentiate into normal renal structures.,
•Occurs in approximately 7 in a million children per year in the U.S. Occurs as part of WARG syndrome (Wilms tumor, aniridia, retardation, genital abnormalities).
•The tumor at the time of discovery was too massive to surgically remove.
http://pathweb.uchc.edu/eAtlas/GU/563.htm   (240 words)

  
 chromosome 11p deletion syndrome
Heredity: Phenotypic variability is related to the breakpoint 11p13--the most common deletion, is associated with aniridia and Wilms tumor are the main features, frequently in association with glaucoma, corneal opacity, optic atrophy, nystagmus, and blepharophimosis.
Deletion of the short arm of chromosome 11 with a variable phenotype: Congenital absence of the iris, genitourinary abnormalities and mental retardation known as aniridia-ambiguous genitalia-mental retardation (AGR) triad; Wilms tumor-aniridia-ambiguous genitalia-mental retardation (WAGR) syndrome; Wilms tumor associated with congenital absence of the iris, genitourinary abnormalities, hemihypertrophy, mental retardation, and other anomalies termed AWTA;
Head and neck: Cranial asymmetry, microcephaly, brachycephaly, prominent forehead, long narrow face, large fontanelles, premature synostosis of metopic sutures, and biparietal foramina.
http://www.nlm.nih.gov/mesh/jablonski/syndromes/syndrome160.html   (327 words)

  
 Wilms tumor
3rd most common kiddie tumor (most common abd tumor)
http://chorus.rad.mcw.edu/doc/00448.html   (18 words)

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