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Topic: Warfarin



  
 Warfarin - Wikipedia, the free encyclopedia
Therapeutic drug monitoring is required, as warfarin has a very narrow therapeutic index, which means the levels in the blood that are effective are close to the levels that cause bleeding.
When initiating warfarin therapy ("warfarinisation"), the doctor will generally decide how strong the anticoagulant therapy needs to be.
During the third trimester, antepartum hemorrhage can occur.
http://en.wikipedia.org/wiki/Warfarin   (1364 words)

  
 UpToDate Patient information: Questions and answers about warfarin (Coumadin®)
The warfarin dose may be adjusted periodically in response to a changing INR or to clinical circumstances that call for an increase or decrease in warfarin therapy.
Warfarin is also used in patients who have a history of developing harmful clots, including patients who have had a stroke, heart attack, a clot which has traveled to the lung (pulmonary embolism), or a blood clot in the leg (deep venous thrombosis or DVT).
— The goal of warfarin therapy is to decrease the clotting tendency of blood, but not to prevent clotting completely.
http://patients.uptodate.com/topic.asp?file=blod_dis/6066   (1853 words)

  
 HeartPoint: Coumadin
Warfarin has a large number of interactions with other drugs.
For now, warfarin has an important place in the treatment of certain medical conditions, and trials to this point have not found suitable alternatives in many situations.
There are several conditions in which warfarin is used.
http://www.heartpoint.com/coumadin.html   (2956 words)

  
 Warfarin
This "prothrombin clotting time" or "protime" measurement is necessary for anyone on warfarin prophylaxis therapy.
However, do not think that if you are on Coumadin/warfarin therapy that you can substitute rat poison; besides the impurities found in the warfarin used for that purpose, many other potentially fatal ingredients are used to enhance the effectiveness of the rodenticide, and none of these would be healthy to consume.
A 1kg rat or a 200mg mouse get a fatal dosage that might not be fatal to, and perhaps not even dangerous to, a 15kg dog or 30kg small child.
http://www.flounder.com/warfarin.htm   (1265 words)

  
 Parkinsn's List Drug DataBase warfarin / Coumadin
According to a review of warfarin drug interactions,D the griseofulvin-warfarin drug interaction is one of the most well-documented warfarin drug interactions.
According to a review of warfarin drug interactionsD the sulfinpyrazone-warfarin drug interaction is one of the most well-documented warfarin drug interactions.
While concomitant therapy with heparin and warfarin makes accurate interpretation of the prothrombin time difficult, brief periods of overlapping therapy with heparin and warfarin routinely occur in clinical practice.
http://www.parkinsons-information-exchange-network-online.com/drugdb/138.html   (3868 words)

  
 Warfarin news articles
Warfarin, one of the most common anticoagulant drugs, is prescribed for millions of patients to prevent harmful clotting after a heart attack, stroke or major...
All patients had had unsuccessful drug therapy or were intolerant to antiarrhythmic drug therapy or were intolerant to warfarin.
Background The management of warfarin therapy is complicated by a wide variation among patients in drug response.
http://www.mongabay.com/drugs/drugs/Warfarin.html   (10753 words)

  
 Warfarin
The acute oral toxicity for warfarin in rats is variously reported to be 3 mg/kg, 1,600 ug/kg, 186 mg/kg (Hartley and Kidd, 1987); 58 mg/kg in female rats.
Another source indicated that an acute oral mallard duck study was performed with a 10% formulation of warfarin.
One study exists on a 50/50 percent formulation of warfarin-sulfaquinoxaline technical.
http://www.the-piedpiper.co.uk/th15(a).htm   (906 words)

  
 Warfarin Versus Low-Molecular-Weight Heparin Therapy in Cancer Patients -- Zacharski et al. 10 (1): 72 -- The Oncologist
in which warfarin was used as an adjuvant therapy for SCLC have
Warfarin Versus Low-Molecular-Weight Heparin Therapy in Cancer Patients -- Zacharski et al.
Randomized trial of chemotherapy and radiation therapy with or without warfarin for limited-stage small-cell lung cancer: a Cancer and Leukemia Group B study.
http://theoncologist.alphamedpress.org/cgi/content/full/10/1/72   (4461 words)

  
 Warfarin, Coumadin
Devil’s claw was associated with purpura (bleeding under the skin) in a patient treated with warfarin.
Possible influences of ginseng on the pharmacokinetics and pharmacodynamics of warfarin in rats.
Warfarin interactions with Chinese traditional medicines: Danshen and methyl salicylate medicated oil.
http://www.truestarhealth.com/Notes/1539003.html   (2630 words)

  
 NetDoctor.co.uk - Information about drugs for Patients
The anticoagulant effect of warfarin can be affected by many medicines.
Your doctor will take regular blood samples and adjust your dose of warfarin as necessary to make your INR fall into the range that has been shown to be effective at preventing blood clots in your particular condition.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
http://www.netdoctor.co.uk/medicines/showpreparation.asp?id=2796   (1548 words)

  
 Warfarin dosing primer on antithrombotic therapy
Warfarin is monitored by the one stage prothrombin time.
The INR is the most reliable way to monitor the prothrombin time.
Warfarin is a narrow therapeutic index drug (NTI).
http://www.careinternet.net/caregiver/warfarin.php   (701 words)

  
 Warfarin definition - Medical Dictionary definitions of popular medical terms
If you are taking Warfarin, talk to your doctor before taking any other prescription or over-the-counter medications.
Aspirin as Good as Warfarin for Some Stroke Prevention
Its effectiveness in controlling pestilent rats and mice led to great commercial success.
http://www.medterms.com/script/main/art.asp?articlekey=11826   (366 words)

  
 Warfarin
This patient information leaflet (PIL) on atrial fibrillation and warfarin is published here by PRODIGY (Prescribing RatiOnally with Decision-support In General-practice studY), which is based at the Sowerby Centre for Health Informatics, University of Newcastle and funded by the NHS Executive.
Warfarin; Popular Works [Publication Type]; Atrial Fibrillation / drug therapy;
This interactive tutorial on Coumadin (a blood-thinning medication) has been produced by the Patient Education Institute, and made available on the Web by the National Library of Medicine MEDLINEplus service.
http://omni.ac.uk/browse/mesh/D014859.html   (249 words)

  
 Warfarin, Complementary and Alternative Healing University
The name Warfarin was derived from Wisconsin Alumni Research Foundation and Coumarin, and was synthesized and used as a rodenticide for nearly a decade prior to its 1954 introduction into clinical medicine.
Do not use in cases of hemophilia, idiopathic thrombocytopenic purpura, serious liver or kidney problems, active peptic ulcer, brain, spine or eye surgery.
An INR of 2~3 remains the recommended intensity of warfarin therapy to prevent thromboembolism in all other patients.
http://alternativehealing.org/warfarin.htm   (629 words)

  
 Home Page
He has given many talks to professional groups on the subject of warfarin.
Lodwick has written many articles on warfarin therapy for Clinical and Applied Thrombosis/Hemostasis, Pharmacy Times, Managed Care, American Journal of Cardiology, Drug Benefit Trends and others.
Disclaimer: Nothing in this information should be used as a justification for discontinuing warfarin therapy.
http://www.warfarinfo.com   (523 words)

  
 America's Riskiest Drugs: Warfarin - Forbes.com
"That really has created kind of a cottage industry to regulate warfarin therapy," says Jonathan Halperin, a cardiologist at Mount Sinai Medical Center.
Possible Complications: Bleeding, blood clots leading to a fatal stroke or heart attack.
Different people require different doses of warfarin, and the same person can require a change in dose if his or her diet changes.
http://www.forbes.com/home/2003/02/24/cx_mh_0224warfarin.html   (573 words)

  
 Warfarin
If you have an allergy to warfarin or any other part of the medicine.
Warfarin prevents the liver from producing the factors that thicken/clot our blood.
If you have any of the following conditions: Bleeding disorder; hemophilia; thrombocytopenia purpura; leukemia; recent surgery of the eye or brain; major regional lumbar block anesthesia; surgery resulting in large, open surfaces.
http://www.umm.edu/altmed/ConsDrugs/Warfarincd.html   (695 words)

  
 Living well with Taro’s Warfarin. Take care because Taro cares.
You know there is more to your life than anticoagulant therapy.
We are committed to helping you achieve a healthy, balanced life—by providing you, your family members and caregivers with valuable information about Taro’s Warfarin.
You play an integral role in your own healthcare.
http://www.tarowarfarin.com   (123 words)

  
 warfarinfo
Since then it has been one of the most widely prescribed drugs in the United States.
(A drug interaction may also have been involved.) The authors state that there are three other cases of absorption of warfarin through the skin causing coagulation problems.
She evidently absorbed enough warfarin through the skin to cause a brain hemorrhage.
http://www.warfarinfo.com/rat-poison.htm   (445 words)

  
 NEJM -- Warfarin, Aspirin, or Both after Myocardial Infarction
Kovacs, M.J., Kearon, C., Rodger, M., Anderson, D.R., Turpie, A.G.G., Bates, S.M., Desjardins, L., Douketis, J., Kahn, S.R., Solymoss, S., Wells, P.S. Single-Arm Study of Bridging Therapy With Low-Molecular-Weight Heparin for Patients at Risk of Arterial Embolism Who Require Temporary Interruption of Warfarin.
receiving warfarin and in 0.17 percent of patients receiving
Earl, M. A., Mauro, V. The Clinical Impact of Administering Warfarin to Post-Myocardial Infarction Patients.
http://content.nejm.org/cgi/content/abstract/347/13/969   (1334 words)

  
 Warfarin dosing and therapy. Coumadin. INR Targets. Vitamin K (Phytonadione) guidelines.
Recent studies confirmed the importance of initiating warfarin therapy with lower doses (eg 5mg) as opposed to older protocols which advocated higher initial dosages (7.5 - 10mg).
In many cases direct quotes are used from this valuable reference.
The previous warfarin calculator was based on a modified version of the Fennerty nomogram.
http://www.globalrph.com/warfarin.htm   (157 words)

  
 Coumadin Online, Description, Chemistry, Ingredients - Warfarin Sodium - RxList Monographs
Crystalline warfarin sodium occurs as a white, odorless, crystalline powder, is discolored by light and is very soluble in water; freely soluble in alcohol; very slightly soluble in chloroform and in ether.
The crystallization of warfarin sodium virtually eliminates trace impurities present in amorphous warfarin.
COUMADIN (crystalline warfarin sodium) is an anticoagulant which acts by inhibiting vitamin K-dependent coagulation factors.
http://www.rxlist.com/cgi/generic/warfarin.htm   (219 words)

  
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http://warfarin.olo.cc   (24 words)

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