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Topic: Virilization



  
 Congenital adrenal hyperplasia due to 21-hydroxylase deficiency - Wikipedia, the free encyclopedia
However, surgery for severely virilized XX infants is often performed and has become a subject of debate in the last decade.
However, the dilemmas surrounding sex assignment of the most severely virilized XX infants have helped shape our understanding of gender identity and sexual orientation, and continue to be a subject of debate.
These reassignments were rarely successful, leading John Money and other influential psychologists and physicians to conclude that gender identity was (1) unrelated to chromosomes, (2) primarily a result of social learning, and (3) could not be easily changed after infancy.
http://en.wikipedia.org/wiki/Congenital_adrenal_hyperplasia_due_to_21-hydroxylase_deficiency   (4872 words)

  
 Virilization - Wikipedia, the free encyclopedia
In common as well as medical usage, virilization often refers to the process of normal male puberty, in which testosterone changes a boy's body into a man's.
In biology and medicine, virilization refers to the development of changes which make a male body different from a female body.
Most of the changes of virilization are produced by androgens.
http://en.wikipedia.org/wiki/Virilization   (493 words)

  
 Pediatric Urology - Genitoplasty
The next degree of virilization is the patient who presents with a vaginal opening distal to the urethral sphincter (low vagina).
Our attention will be focused on the surgical management of the virilized female with 21-hydroxylase deficiency since this is the most common type of CAH patient encountered.
When dexamethasone is begun early in the first trimester, effective prevention of virilization is accomplished 86% of the time.13 Still 14% of infants become virilized despite treatment, and not all at risk pregnancies can be identified prenatally.
http://www.cornellurology.com/uro/cornell/pediatrics/genitoplasty.shtml   (2840 words)

  
 Congenital Adrenal Hyperplasia
Simple virilizing form: Excessive prenatal production of androgens in affected females results in masculinization of the reproductive tract to a point that the sex of the newborn is not clear ("ambiguous genitalia") or appears male-like.
These procedures are complicated by concerns about when the surgery should be performed, gender identity of the patient and other factors.
A number of surigical procedures have been developed to correct the genital abnormalities of girls with the virilizing form of CAH.
http://arbl.cvmbs.colostate.edu/hbooks/pathphys/endocrine/adrenal/cah.html   (939 words)

  
 Technical Report: Congenital Adrenal Hyperplasia -- Section on Endocrinology and Committee on Genetics 106 (6): 1511 -- ...
the androgen biosynthesis pathway, producing virilization in the
therapy after that time would prevent progression of virilization.
About 75% of affected infants have the salt-losing, virilizing
http://aappolicy.aappublications.org/cgi/content/full/pediatrics;106/6/1511   (5394 words)

  
 Oxandrin Paper
Discontinuation of drug therapy at the time of evidence of mild virilism is necessary to prevent irreversible virilization.
Serum testosterone level went up from 21 mg/dl to 91 mg/dl, but she showed no evidence of clinical virilization.
She tolerated the treatment well, and there was no evidence of virilization or adverse effects during that period.
http://www.hereditaryangioedema.com/oxscott.htm   (1990 words)

  
 Virilization of the Male Pouch Young of the Tammar Wallaby Does Not Appear to be Mediated by Plasma Testosterone or ...
that virilization is likely mediated by some testis-derived
The existence of such a pathway has not been demonstrated to
Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas 75235
http://www.biolreprod.org/cgi/content/full/61/2/471   (3724 words)

  
 Korean Journal of Radiology
In our case, the enhanced solid nature of ovarian masses may have been connected to the symptomatic clinical presentation, which was in contrast to the aforementioned "silent" case.
During a normal pregnancy, the maternal circulating testosterone level can increase and especially in the third trimester.
The serum levels of total testosterone may rise up to seven times the nonpregnant levels, and this physiological condition does not cause virilization.
http://www.kjronline.org/abstract/view_articletext.asp?year=2005&page=44   (1406 words)

  
 JPMA :::
Female patients were classified as having the simple virilizing (SV) form of CAH if they had prenatal virilization of external genitalia, but no signs of severe mineralocorticoid deficiency.
Sex, both at presentation and after chromosomal analysis, chronological age, bone age, family history of any similarly affected member or child death, and parental consanguinity were also recorded from the file.
Eighteen (28.6%) patients presented with simple virilization CAH; 6 were phenotypic females, 2 were phenotypic males and 10 were ambiguous.
http://jpma.org.pk/jpma/10Oct04/fulltext5.htm   (1644 words)

  
 OCCURRENCE OF VIRILIXATION SIGNALS IN A FEMALE MARMOSET Leontopithecus chrysomelas (CALLITRICHIDAE; PRIMATES) WITH ...
The aim of this work is to study a female Leontopithecus chrysomelas with XX/XY chimerism and virilization signals, and discuss this novel condition.
However, natural chimerism without the freemartin condition seen in other species is still an enigma because it allows hematopoietic and bone marrow chimerism even if it does not result in freemartinism between twins of different sexes.
The animal studied here presented virilization of external genitalia, characterized by enlarged clitoris and constriction of vulvar opening.
http://www.isrvma.org/article/60_3_2.htm   (1637 words)

  
 Medical Dictionary: Virilization - WrongDiagnosis.com
Virilization: Another name for Masculinisation (or close medical condition association).
Virilization (medical condition): Increased male physical appearance in females
http://www.wrongdiagnosis.com/medical/virilization.htm   (106 words)

  
 BRAVTEST : BC Cancer Agency
Close monitoring is required, especially during the early stages of therapy.
If clinical circumstances allow for an observation period, observe for rebound regression.
Virilization: Some effects such as voice changes or clitoromegaly may not be reversible.
http://www.bccancer.bc.ca/HPI/ChemotherapyProtocols/Breast/BRAVTEST.htm   (362 words)

  
 Virilization of Young Children After Topical Androgen Use by Their Parents -- Kunz et al. 114 (1): 282 -- Pediatrics
All our patients developed significant virilization from contact
We report our experience with 4 children who were
Virilization of young children may have negative physical and
http://pediatrics.aappublications.org/cgi/content/full/114/1/282   (1630 words)

  
 Maternal serum androgens in pregnant women with polycystic ovarian syndrome: possible implications in prenatal ...
Hensleigh, P.A., Carter, R.P. and Grotjan, H.E. (1975) Foetal protection against masculinization with hyperreactio luteinalis and virilization.
of androgens does not lead to fetal virilization.
Barnes, R.B., Rosenfield, R.L., Ehrmann, D.A., Cara, J.F., Cuttler, L., Levitsky, L.L. and Rosenthal, I.M. (1994) Ovarian hyperandrogenism as a result of congenital adrenal virilizing disorders: evidence for perinatal masculinization of neuroendocrine function in women.
http://humrep.oxfordjournals.org/cgi/content/full/17/10/2573   (3902 words)

  
 Virilize definition - Medical Dictionary definitions of popular medical terms
The noun form of "virilize" is "virilization." "Virilize" and "virilization" are not to be confused with "masculinize" and "masculinization" which refer to the development of male characteristics in a male on a normal schedule during or on a precocious schedule in a younger boy.
"Virilize" and "virilization" are derived from the Latin word "virilis" (masculine).
Virilize definition - Medical Dictionary definitions of popular medical terms
http://www.medterms.com/script/main/art.asp?articlekey=12466   (497 words)

  
 Steroid Side Effects - Effects of Steroids - Steroid.com
Some typical signs of virilization are the development of a deeper voice, hirsuitism (growth of excess body hair), enlargement of external genitalia (clitoral enlargement), and possible male pattern baldness, or acne on the face or body.
This side effect on women is often reversible after the cycle has ended.
http://www.steroid.com/side.php   (4138 words)

  
 A FEW OF THE CAUSES
If the timing is right, the genital anlagen is virilized with effects ranging from enlarged clitoris to the development of a complete phallus and the fusing of the labia.
It is noteworthy that the use of progestin is not effective in the prevention of miscarriage.
The virilization only occurs prenatally and the endocrinological functionality is unchanged, ie.
http://www.snowcrest.net/starwalker/Chromosomes/intersexed/afewcauses.html   (1291 words)

  
 Biomolecular Chemistry 704
However, no mineralocorticoids such as DOC or Aldosterone would be made, thus Na+ wasting occurs.
E. Why does patient I exhibit salt wasting and virilization?
With the present cases, you observe that patient I responds to the glucocorticoid therapy by a lessing of the degree of virilization, although some salt wasting still occurs.
http://www.bmolchem.wisc.edu/teachinglab/fall704/module5/pjbmod5a8-13_04.htm   (2402 words)

  
 Intersex
This is rare and may occur in babies of mothers with virilizing ovarian or adrenal tumour.
All CAH patients require cortisole treatment - 50mg/m2 Hydrocortisone I.V. as bolus followed by maintenance treatment.
This complex induces the final effect for the male phenotype, in particular virilization of external genitalia and urogenital sinus (male urethra).
http://www.bui.ac.uk/Tutorials/intersex.htm   (1290 words)

  
 Virilization: Adrenal Gland Disorders: Merck Manual Home Edition
The combination of body changes makes virilization relatively easy for a doctor to recognize.
The mild virilization caused by cystic ovaries may need no treatment.
Athletes who take large amounts of androgens (anabolic steroids) to increase their muscle bulk may develop symptoms of virilization (see Other Drugs of Abuse
http://www.merck.com/mmhe/sec13/ch164/ch164d.html?alt=pf   (381 words)

  
 Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency -- White and Speiser 21 (3): 245 -- Endocrine Reviews
female offspring appear to have no genital virilization (109).
virilizing patients, testicular integrity may be normal even
Although patients with the simple virilizing form of the disease
http://edrv.endojournals.org/cgi/content/full/21/3/245   (8778 words)

  
 Medical Conditions - Reproductive Endocrinology
Virilization is a more extreme form of hyperandrogenism, in which a female develops secondary male sex characteristics including voice changes, male-pattern baldness, cliteromegaly and skeletal muscle hypertrophy.
Excess androgens in females can lead to hirsutism, severe acne and menstrual problems such as oligomenorrhea or primary and secondary amenorrhea.
Abnormally high circulating levels of DHEA-SO and high bioactive testosterone (as reflected, for example, in elevations of the traditional FAI), the primary culprits of hyperandrogenism, may be induced either metabolically or through the use of anabolic steroids.
http://www.dpcweb.com/medical/reproductive_endocrinology/hyperandro_virilization.html   (417 words)

  
 International Union of Pure and Applied Chemistry
Prevention of genital virilization in female newborns with classic CAH avoids the risk of sex misassignment and diminishes the need for corrective surgery and the resulting psychological impact that may extend into adulthood.
Based on our experience, prenatal diagnosis and treatment of 21-hydroxylase deficiency is effective in significantly reducing or eliminating virilization in the newborn female.
Prenatal treatment of CAH with dexamethasone has been successfully utilized for over a decade.
http://www.iupac.org/publications/pac/2003/7511/7511x2013.html   (267 words)

  
 THE MERCK MANUAL, Sec. 19, Ch. 269, Endocrine And Metabolic Disorders
An affected infant may present with ambiguity of the external genitalia, thereby providing few initial diagnostic clues, because an undervirilized male and an overvirilized female infant cannot be distinguished on physical examination.
These disorders result in virilization of affected female infants and in undervirilization of affected male infants.
When the enzyme block (eg, 21-hydroxylase deficiency) causes androgens to accumulate, the disorder is a virilizing form of CAH, causing varying degrees of virilization of an affected female fetus.
http://www.merck.com/mrkshared/mmanual/section19/chapter269/269f.jsp   (788 words)

  
 Medical Conditions - Reproductive Endocrinology
Although serum testosterone levels appear to correlate with the degree of virilization in women, nearly 25% of women with varying degrees of virilization have serum testosterone levels within the reference range.
Virilization is associated with the administration of androgens and endogenous overproduction of testosterone.
Common causes of increased serum levels include polycystic ovary syndrome (PCOS or Stein-Leventhal syndrome), hirsutism, ovarian tumors, adrenal tumors, adrenal hyperplasia and Cushing's syndrome.
http://www.dpcweb.com/medical/reproductive_endocrinology/testosterone.html   (769 words)

  
 Hirsutism
Licorice could be considered an adjuvant therapy of hirsutism and...
A directory of UK health, disease, illness and related medical websites that provide patient information.
hereditary / constitutional / racial hirsutism (no acne or virilism).
http://hirsutism.arnovalleycommunity.com   (1914 words)

  
 Best Practice of Medicine-Patient Guide - Excessive Hairiness
Hirsuitism is sometimes linked to changes that make the body more masculine (virilization), which can happen to both males and females.
Hirsutism may be caused by medical conditions that cause the body to have an excess of certain hormones, or by some medications.
Signs of virilization include deepening of the voice, increased muscle mass, decreased breast size, enlarged genitals, and increased libido.
http://merck.micromedex.com/index.asp?page=bhg_report&article_id=BHG01EN13§ion=report   (2101 words)

  
 Unexpected Virilization in Male Mice Lacking Steroid 5{alpha}-Reductase Enzymes -- Mahendroo et al. 142 (11): 4652 -- ...
in the virilization of the urogenital sinus and genital tubercle
In the current study we report the construction and analysis
With respect to the virilized phenotypes of 5
http://endo.endojournals.org/cgi/content/full/142/11/4652   (7174 words)

  
 Virilization in Bilateral Macronodular Adrenal Hyperplasia Controlled by Luteinizing Hormone -- Goodarzi et al. 88 (1): ...
We determined that our patient had a LH-dependent virilizing
Serum total testosterone level in the virilized patient with bilateral macronodular adrenal hyperplasia during gonadotropin stimulation and suppression.
women with virilization may present for medical care earlier
http://jcem.endojournals.org/cgi/content/full/88/1/73   (2364 words)

  
 eMedicine - Hirsutism : Article by George T Griffing, MD
In this approach, hair growth is judged in each of 11 androgen-sensitive areas.
The disorder often is familial in nature and may be associated with obesity and insulin resistance.
The patient's hirsutism is not caused by well-defined abnormalities such as an androgen-secreting tumor or CAH.
http://www.emedicine.com/med/topic1017.htm   (5317 words)

  
 AccessMedicine - Harrison's Internal Medicine: Hirsutism and Virilization: Introduction
AccessMedicine - Harrison's Internal Medicine: Hirsutism and Virilization: Introduction
Virilization refers to the state in which androgen levels are sufficiently high to cause additional signs and symptoms such as deepening of the voice, breast atrophy, increased muscle bulk, clitoromegaly, and increased libido; virilization is an ominous sign that suggests the possibility of an ovarian or adrenal neoplasm...."
Any use is subject to the Terms of Use and Notice.
http://www.accessmedicine.com/content.aspx?aID=56402   (259 words)

  
 Virilization
To find more information on specific conditions, please visit our partner sites:
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition.
This may include an increase in body hair, facial hair, a deepening of the voice, male-pattern baldness, and clitoral enlargement.
http://www.healthscout.com/ency/1/002339.html   (156 words)

  
 Body hair transplant info and price
doesn't in Virilization appearance body hair men is an extremely hair
HAIR 34 PRODUCTS: Virilization loss to the_body body hair,  Female body hair and our transplants,
Jeffrey also performs and and Loss Women - in increased hair Virilization appearance secondary Laser Removal extremely common hair
http://body-hair-transplant.menproblems.info   (5241 words)

  
 Functioning Ovarian Tumors: Direct and Indirect Findings at MR Imaging -- Tanaka et al. 24 (Supplement 1): S147 -- ...
Virilization occurs in only about one-third of patients.
Virilization is associated with a more severe degree of hyperandrogenism
tumors in patients with virilization are often small and difficult
http://radiographics.rsnajnls.org/cgi/content/full/24/suppl_1/S147   (8424 words)

  
 XHMEIO Rudas - Clincal Laboratory Cyprus : > DHEA-Sulphate / Monday, May 15, 2006 ...
Female infertility, amenorrhea, or hirsutism, androgen excess (hirsutism and/or virilization), and adrenocortical disorders
http://www.bi-lab.net/bilab/en/bilab_DHEA-Sulphate/default.aspx?pageid=163   (99 words)

  
 Hirsutism - causes and treatments
All these should be considered in any patients with hirsutism.
Most patients with hirsutism will have some disturbance of menstruation.
Hirsutism due to PCOS may be severe and effect all androgen-dependant areas on the face and body.
http://hirsutism.homestead.com   (1264 words)

  
 Hirsutism - New Treatments, May 2, 2006
Virilization is less common than hirsutism and is more often associated with a potentially serious disorder such as an ovarian or adrenal tumor.
The primary mechanism leading to the development of hirsutism and virilization is increased secretion of androgens by the ovary or adrenal.
Although it may be the initial sign of a serious underlying disorder, hirsutism by itself is usually benign and is frequently associated with PCOS.
http://www.ccspublishing.com/journals3a/hirsutism.htm   (645 words)

  
 eMedicine - Adrenal Carcinoma : Article by Lawrence C Wolfe, MD
Approximately 50-60% of patients with adrenal cortical carcinoma present with virilization.
In 60% of cases, the patient's history includes elements of adrenal cortical hormone production and a palpable mass.
Patients with adrenal tumors often present with a history of adrenal cortical hormone production, including Cushingoid features, physical changes (see below), and virilization from increased androgen production.
http://www.emedicine.com/ped/topic41.htm   (2286 words)

  
 Extraovarian Steroid Cell Tumor ‘Not Otherwise Specified’ as a Rare Cause of Virilization in ...
As the glucocorticoid therapy did not normalize high levels of 17-OHP and androgens, and the DNA analysis did not demonstrate a mutation causing CAH, a laparotomy was performed.
Regarding the age of our patient and pathohistological findings of the tumor, her prognosis is favorable.
Background: We present a 12-year-old girl with a 5-year history of progressive virilization.
http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowFulltext&ProduktNr=224036&Ausgabe=227687&ArtikelNr=50006   (237 words)

  
 The Adrenal Gland
The major concern is virilization of females by a disorder that results in excess androgen production by the adrenal cortex.
In androgenital syndromes associated with hirsutism or virilization, we are concerned with excess androgen production by the adrenal cortex in a female.
There are four major presentations; remember, however, that like all things biological, these conditions lie on a "continuous" scale.
http://faculty.etsu.edu/currie/adrenal.htm   (2289 words)

  
 Ovarian stromal luteoma - a rare cause of postmenopausal virilization diagnosed by selective ovarian venous sampling
Virilization in post-menopausal women is usually the result of androgen production by ovarian or adrenal tumours.
Stromal luteomas are a rare cause of virilization and hyperandrogenism in postmenopausal women.They are small tumours and are often not detected on imaging.This case highlights the importance of selective ovarian venous sampling in the investigation and detection of these uncommon tumours.
We present a case of an occult virilizing ovarian luteoma diagnosed by selective ovarian venous sampling.
http://www.endocrine-abstracts.org/ea/0007/ea0007p88.htm   (315 words)

  
 Medical Dictionary: Virilization - CureResearch.com
Virilization (condition): Increased male physical appearance in females
Information provided on this site is for informational purposes only; it is not intended as a substitute for advice from your own medical team.
http://www.cureresearch.com/medical/virilization_printer.htm   (84 words)

  
 Hair Removal
Therefore enlargement of clitoris, lack of breast development etc needs to be considered before finalizing treatment for unwanted hair.
But failure to offer permanent reduction may be due to non performance of diet, medicines, or if internal chemistry (hormones) is unattended.
It is very important to examine a woman coming for unwanted hair, and see if she has signs of virilization (enlarged clitoris) and /or signs of defeminization (less feminine curves).
http://www.magiclaser.com/HTML/hairremoval.htm   (916 words)

  
 [No title]
\par\ls1\ilvl2 \u8226 \'95\tab More common than virilization \par \u8226 \'95\tab Usually associated with milder androgen excess, a gradual onset, and usually not associated with either a severe enzymatic defect or neoplasm.
http://www.nova.edu/noteservice/repro/docs/LectureSupplement31.doc   (480 words)

  
 XHMEIO Rudas - Clincal Laboratory Cyprus : > Virilization panel / Monday, May 15, 2006 ...
Virilization tests are performed using the following Equipment:
XHMEIO Rudas - Clincal Laboratory Cyprus : > Virilization panel / Monday, May 15, 2006
http://www.bi-lab.net/bilab/en/bilab_virilization/default.aspx?pageid=491   (50 words)

  
 Virilization - A Medical Reference Article
A resource with information on over 10,000 medical topics including: Virilization
http://www.umm.edu/dwp/007775.htm   (21 words)

  
 virilization, inadequate in males - General Practice Notebook
Rarely they may be XX with an H-Y antigen, the element of the Y chromosome which determines maleness.
virilization, inadequate in males - General Practice Notebook
Males with inadequate virilization have one Y chromosome and one or more X chromosomes.
http://www.gpnotebook.co.uk/simplepage.cfm?ID=705036331   (812 words)

  
 NEJM -- Measurements of Serum Mullerian Inhibiting Substance in the Evaluation of Children with Nonpalpable Gonads
with virilization and nonpalpable gonads, only those with testicular
in 65 children with virilization at birth and nonpalpable gonads
Misra, M., MacLaughlin, D. T., Donahoe, P. K., Lee, M. The Role of Mullerian Inhibiting Substance in the Evaluation of Phenotypic Female Patients with Mild Degrees of Virilization.
http://content.nejm.org/cgi/content/abstract/336/21/1480   (678 words)

  
 CyberHealth #11
This is part of the overall VIRILIZATION that can be seen when women become estrogen-deficient.
This becomes particularly noticeable after menopause, when untreated women become androgen-dominant and even treated women typically don’t come up to the levels of estrogens they used to have premenopausally.
Specifically, this is the "virilization of the voice."
http://www.antiaging.com/cyberhealth/CyberHealth_11.htm   (7484 words)

  
 Severe virilization in a postmenopausal woman: a case report
Severe virilization in a postmenopausal woman: a case report
http://www.docguide.com/news/content.nsf/WebOpenPaper_TopAbstracts?OpenAgent&newsid=8525697700573E1885256FD7007ACE6F   (9 words)

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