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Topic: Vasculitis



  
 Nat'l Jewish-Med. Sci. Update-Vasculitis
Combined therapy with cyclophosphamide and a corticosteroid induces remission in about 95% of patients with severe vasculitis.
Corticosteroids are the treatment of choice for patients with hypersensitivity vasculitis who need specific therapy.
However, in our experience some patients with polyarteritis nodosa, hypersensitivity vasculitis, and Wegener's granulomatosis have had some response to plasmapheresis when used in concert with other therapies.
http://library.nationaljewish.org/MSU/12n5MSU_Vasculitis.html   (2270 words)

  
 Vasculitis
This is an extremely serious, systemic (affecting systems throughout the body) form of vasculitis.
Because so little is known about what causes a particular individual to develop vasculitis, there are no known ways to prevent it.
Ledford, Dennis K. "Immunologic aspects of Vasculitis and Cardiovascular Disease." The Journal of the American Medical Association 278, no. 22 (10 Dec. 1997): 1962+.
http://www.lifesteps.com/gm/Atoz/ency/vasculitis.jsp   (1930 words)

  
 eMedicine - Leukocytoclastic Vasculitis : Article by Jeffrey P Callen, MD
Patients with vasculitis of their skin may experience itching, burning, or pain, or they may have asymptomatic lesions.
Patients with hypocomplementemic urticarial vasculitis may develop chronic obstructive pulmonary disease, and a careful examination of the heart and lungs is warranted.
Vasculitis of the skin may occur in the absence of any systemic disease.
http://www.emedicine.com/med/topic2930.htm   (3772 words)

  
 Lupus And Vasculitis
In other non-lupus types of vasculitis, such as temporal arteritis, there is sudden loss of part or all of the vision in one eye, usually accompanied by severe headache.
These are the most common vasculitis skin lesions, but hives, itchy lumpy rash, and painful or tender lumps can occur.
For example, if your physician is a rheumatologist and you have visual complaints which could be indicative of vasculitis, you may be referred to an ophthalmologist.
http://www.hamline.edu/lupus/articles/Lupus_and_Vasculitis.html   (1775 words)

  
 Arthritis Research Campaign Vasculitis
This booklet explains what vasculitis is, how it is recognized, how it is treated, and what you can do to help your treatment.
When part of your body is inflamed, it swells and is usually uncomfortable or painful (although with many types of vasculitis you will not be able to see any swelling on the outside of the body).
On the other hand, Henoch–Schönlein purpura (HSP), which is an allergic form of vasculitis mainly affecting the skin, is much more common in children than in adults.
http://www.arc.org.uk/about_arth/booklets/6047/6047.htm   (4395 words)

  
 HSS - New Treatment Strategies for Systemic Vasculitis
I will tell you that in our practice at the Vasculitis Center at the Cleveland Clinic, one of the greatest pitfalls in the management of vasculitis that we see of patients referred into us, are the patients who are "Cytoxan failures." Virtually all of these patients come in with active disease on pulse therapy.
I believe that pulse therapy works for many patients with systemic necrotizing vasculitis.
This randomized patients to pulse therapy 0.75 grams per metered square versus oral for ANCA-associated vasculitis; all of them had renal disease, and it was associated with 57% less total drug.
http://rheumatology.hss.edu/phys/gr/calabrese_lec_tran.asp   (7301 words)

  
 Specific Vasculitides
The goal of therapy is to stop all damage that is continuing to occur as a result of vasculitis.
The goal of therapy is to stop all damage due to vasculitis.
Calabrese L: Therapy of systemic vasculitis Neurologic Clinics of North America 15:973-992.
http://www2.ccf.org/inssys/specificvasc.htm   (5089 words)

  
 Vasculitis Update
The European Vasculitis Study Group (EUVAS) was formed in 1993 following a grant from the EU with the intention of performing multi-centre studies of therapy in systemic vasculitis.
EUVAS is an informal group of doctors interested in the care of patients with primary systemic vasculitis and is open to any interested doctor.
EUVAS stimulates and facilitates top-level scientific and clinical collaboration concerning primary vasculitis.
http://www.vasculitis.org   (106 words)

  
 Baylor Neurology Case of the Month
Although the "gold standard" for all forms of vasculitis is histologic confirmation, a recent review by Calabrese et al., suggests that nearly one in four biopsy procedures may result in a false-negative outcome.
However, the angiogram itself carries a risk of stroke of 1 to 2%.
Since we found no etiology for the stroke, an angiogram might have revealed the cause of the initial stroke.
http://www.bcm.tmc.edu/neurol/challeng/pat5/summary.html   (1810 words)

  
 Neurology of the vasculitides and connective tissue diseases -- Moore and Richardson 65 (1): 10 -- Journal of ...
Peripheral neuropathy in systemic vasculitis: clinical and electrophysiologic study of 22 patients.
Systemic vasculitis with asthma and eosinophilia: a clinical approach to the Churg-Strauss syndrome.
Polyarteritis nodosa, which affects medium and small sized vessels throughout the body, is the classic systemic necrotising
http://jnnp.bmjjournals.com/cgi/content/full/65/1/10   (7323 words)

  
 VASCULITIS
European Vasculitis Study Group (EUVAS) was originally formed in 1993 as the European Community Concerted Action Group for the Study of Therapeutic Trials in Systemic Vasculitis (ECSYSVASTRIAL, contract no. BMH1-CT93-1078) with the intention of performing multi-centre studies of therapy in systemic vasculitis.
RDL Vasculitis And Vasculitis Testing At Rheumatology Diagnostics Laboratory ``is an innovative immunology laboratory, providing services to internists, rheumatologists, infectious disease specialists, hospitals, and medical laboratories, dedicated to the principles of cost effectiveness and excellence in laboratory immunology.``
Intravenous immunoglobulin as sole therapy for systemic vasculitis DRW.
http://www.edae.gr/vasculitis.html   (2409 words)

  
 Baylor Neurology Case of the Month
The vasculitis is most frequently evidenced as skin infarctions/ulcerations and a mononeuritis multiplex.
Treatment of the systemic vasculitis associated with Rheumatoid Arthritis has typically consisted of steroid therapy.
This small sample size of nine patients with Rheumatoid Arthritis manifesting a cerebral vasculitis suggests aggressive therapy is warranted.
http://www.bcm.tmc.edu/neurol/challeng/pat29/summary.html   (1666 words)

  
 MedlinePlus: Vasculitis
The primary NIH organization for research on Vasculitis is the National Institute of Allergy and Infectious Diseases
Atlas of the Body: The Circulatory System -- Venous (American Medical Association)
Atlas of the Body: The Circulatory System -- Arterial (American Medical Association)
http://www.nlm.nih.gov/medlineplus/vasculitis.html   (256 words)

  
 Vasculitis
Cutaneous vasculitis causes a skin rash (see the picture above) and sometimes pain.
Sometimes it affects many organs at the same time (systemic vasculitis).
Vasculitis in the heart may result in symptoms similar to a heart attack, and in the brain it may cause confusion, symptoms of a stroke or fits.
http://renux.dmed.ed.ac.uk/EdREN/EdRenINFObits/VasculitisLong.html   (1040 words)

  
 MedlinePlus Medical Encyclopedia: Allergic vasculitis
Avoid exposure to medications to which there are known allergies.
Calling your health care provider Return to top
The diagnosis is primarily based on a history of skin lesions that develop after exposure to medications or a foreign substance (antigen) and the pattern of symptoms.
http://www.nlm.nih.gov/medlineplus/ency/article/000874.htm   (405 words)

  
 CNS Vasculitis in Autoimmune Disease: MR Imaging Findings and Correlation with Angiography -- Pomper et al. 20 (1): 75 ...
increasingly important as more effective therapies for CNS vasculitis
Other imaging techniques with the potential to enhance lesion
To our knowledge, only one other study has attempted to correlate
http://www.ajnr.org/cgi/content/full/20/1/75   (4035 words)

  
 Central Nervous System Vasculitis discussed by Johns Hopkins Vasculitis Center
The availability of powerful immunosuppressive therapy, however, has significantly improved the prognosis for people with this condition.
The American College of Physicians has given us permission to make this information available to patients contacting our Website:
The best therapy has not been established: many patients are treated with prednisone and cyclophosphamide.
http://vasculitis.med.jhu.edu/typesof/cns.html   (1900 words)

  
 The Vasculitis Clinical Research Consortium
The Vasculitis Clinical Research Consortium (VCRC) is an integrated group of academic medical centers, patient support organizations, and clinical research resources dedicated to conducting clinical research in different forms of vasculitis.
It is our goal to improve the care of patients with Wegener's granulomatosis, microscopic polyangiitis, Churg-Strauss syndrome, polyarteritis nodosa, Takayasu's arteritis, and giant cell (temporal) arteritis.
http://www.rarediseasesnetwork.org/vcrc   (92 words)

  
 Final Diagnosis -- Case 59
In cases of spinal SAH associated with vasculitis, breakdown of the inflamed vessel wall is assumed to be the cause of hemorrhage.
A spinal subdural haematoma due to granulomatous angiitis of the nervous system in a patient with non-Hodgkin's lymphoma has also been reported (10).
According to modern classifications (1), PAN is excluded on the basis that it affects predominantly medium-sized vessels and not venules, and is rarely associated with ANCA.
http://path.upmc.edu/divisions/neuropath/bpath/cases/case59/dx.html   (530 words)

  
 EHS: Magnetic Resonance Imaging - Sample Chapter 55: Ischemia, 7
The authors concluded that a negative MRI was able to exclude intracranial vasculitis more definitively than a negative angiogram and furthermore makes the likelihood of finding vasculitis with angiography alone negligible.
The vasculitis may be the primary disease process (e.g., polyarteritis nodosa) or may be a secondary manifestation of a generalized systemic disease (e.g., systemic lupus erythematosus).
comparing brain MRI and invasive cerebral angiography in diagnosing cerebral vasculitis, the MR examination was abnormal in all the patients diagnosed with vasculitis who had both studies.
http://www3.us.elsevierhealth.com/Mosby/Stark-Bradley/C88_055g.html   (1578 words)

  
 Editorial
Clearly limiting our ability to better understand these relatively obscure forms of arteritis are a number of factors that continue to be difficult to overcome.
Among these are a lack of: clinical signs and symptoms of high specificity, efficient noninvasive diagnostic tests, relevant animal models, extremely limited biologic materials for pathophysiologic investigation, longterm followup of large numbers of patients, and controlled therapeutic trials.
Despite such limitations, vasculitis of the CNS in general and primary angiitis of the CNS (PACNS) in particular have become the subject of increasing interest to clinicians driven in large part by increased awareness, coupled to our growing sophistication and aggressive use of neurodiagnostic modalities.
http://www.jrheum.com/abstracts/editorials01/465.html   (1345 words)

  
 Wegener's Granulomatosis, NIAID Fact Sheets
NIAID and other parts of NIH support research on Wegener's granulomatosis and related forms of vasculitis at medical centers throughout the country through the extramural grants program.
Therefore, NIH researchers have continued to study Wegener's granulomatosis to understand the causes of the disease and to develop new treatments.
A biopsy is very important both to confirm the presence of the disease and also to make sure other disorders that may have similar signs and symptoms are not present.
http://www.niaid.nih.gov/factsheets/wegeners.htm   (2024 words)

  
 Immune Neuropathies: Axonal
Conduction block: In acute phase (1st 1 to 2 weeks) only
Anti-viral therapy: Patients with vasculitis and Hepatitis B or C
Systemic connective tissue disorders and Vasculitis: Specific syndromes
http://www.neuro.wustl.edu/neuromuscular/antibody/pnimax.html   (804 words)

  
 Introduction: Vasculitic Disorders of Connective Tissue: Merck Manual Home Edition
Vasculitis is not a disease but rather a disease process.
Vasculitis commonly occurs in disorders that affect connective tissue, but it can also occur in conditions that do not affect connective tissue.
Vasculitis may be limited to veins, large arteries, small arteries, or capillaries, or it may be limited to vessels in one part of the body, such as the head, leg, or kidney.
http://www.merck.com/mmhe/sec05/ch069/ch069a.html   (385 words)

  
 Info and facts on 'Vasculitis'
In medicine (The branches of medical science that deal with nonsurgical techniques), vasculitis (plural: vasculitides) is a group of diseases featuring inflammation (A response of body tissues to injury or irritation; characterized by pain and swelling and redness and heat) of the wall of blood vessel (A vessel in which blood circulates) s.
Lupus erythematosus (A chronic inflammatory collagen disease affecting connective tissue (skin or joints)) vasculitis
Its main causes are autoimmune disorder (Any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues) s and (occasionally) infection (The pathological state resulting from the invasion of the body by pathogenic microorganisms) s.
http://www.absoluteastronomy.com/encyclopedia/v/va/vasculitis.htm   (465 words)

  
 vasculitis - definition of vasculitis in Encyclopedia
Infectious vasculitis is generally treated with directed antibiotics, while autoimmune forms often require treatment with immune suppression: steroids, DMARDs ("steroid-sparing agents") or cyclophosphamide (a mild form of chemotherapy).
While most vasculitides are rare diseases, they generally affect several organ systems and can cause severe disability.
While these measurements have a low positive and negative predictive value (due to the high rates of both false positives and false negatives), they can direct the clinician to specific causes for vasculitis.
http://encyclopedia.laborlawtalk.com/vasculitis   (216 words)

  
 Vasculitis in a Dog Resembling Isolated Angiitis of the Central Nervous System in Humans -- Sasaki et al. 40 (1): 95 -- ...
cell vasculitis of the brain, a clinical and neuropathologic
In humans, the vasculitides are a large group of disorders which
Vasculitis in a Dog Resembling Isolated Angiitis of the Central Nervous System in Humans
http://www.vetpathology.org/cgi/content/full/40/1/95   (931 words)

  
 [Frontiers in Bioscience 9, 946-955, January 1, 2004]
One can see primary CNS vasculitis as a distinct entity which is primarily manifested as central nervous system injury in a vascular distribution or the vasculitic process can be secondary to a systemic disorder such as systemic lupus erythematosus (SLE) or polyarteritis nodosa (PAN).
It is quite probable that there is a genetic predisposition in certain individuals and this can lead to an enhanced risk of a vasculitic process when there is exposure to a particular antigen that "sets off" the immune system.
Vasculitis of the central nervous system can be of several varieties depending upon the vessel(s) involved and type of disorder.
http://www.bioscience.org/2004/v9/af/1259/3.htm   (265 words)

  
 Brain Inflammation
Inflammatory diseases of the brain include abscess, meningitis, encephalitis and vasculitis.
Mucormycosis is seen most often in patients with poorly controlled diabetes.
Brain involvement typically consists of a meningo-encephalitis that may cause brain atrophy, intracranial calcifications (not as common as in the other congenital infections), microcephaly, delayed myelination, and vasculitis.
http://spinwarp.ucsd.edu/NeuroWeb/Text/br-200.htm   (3690 words)

  
 CNSV-network - information and support for the CNS Vasculitis community
People with CNS Vasculitis face serious disabling symptoms such as head pain, confusion, paralysis, mental changes, fatigue, impaired cognition, sensitivity to overstimulation, and a host of other neurological problems.
CNSV is very difficult to diagnose and treat.
There is virtually no research into discovering better methods of diagnosing and treating Central Nervous System Vasculitis.
http://www.cnsv.net   (159 words)

  
 Cerebral vasculitis--recognition, diagnosis and management -- Scolding et al. 90 (1): 61 -- QJM
Cerebral vasculitis is a serious but uncommon condition which presents
http://qjmed.oupjournals.org/cgi/content/abstract/90/1/61   (215 words)

  
 News - Systemic Small-Vessel Vasculitis May be Commonly Misdiagnosed as Polymyalgia Rheumatica
SVV can cause renal failure and is usually fatal within 6 months in the absence of early immunosuppressive therapy.
News - Systemic Small-Vessel Vasculitis May be Commonly Misdiagnosed as Polymyalgia Rheumatica
Systemic Small-Vessel Vasculitis May be Commonly Misdiagnosed as Polymyalgia Rheumatica
http://www.docguide.com/news/content.nsf/news/8525697700573E1885256E7F00329738   (558 words)

  
 Indian Pediatrics - Editorial
The typical clinical manifestations include multifocal strokes or encephalopathy, often associated with severe headache(3).
As in our case, there is relative absence of constitutional symptoms (like fever, loss of weight, myalgia, arthralgia, etc.) which suggest the presence of systemic vasculitis conditions with CNS involve-ment(1,4).
• Primary angiitis of the central nervous system is a rare idiopathic disorder with recurrent vasculitis restricted to the central nervous system.
http://www.indianpediatrics.net/july2002/july-684-689.htm   (1765 words)

  
 News ACR San Diego 1998. Vasculite primitiva SNC
Among the non-PACNS cases, 12 were initially treated as vasculitis but had this therapy discontinued after evaluation.
Conclusions: 1) Even among cases with high pre-test probability for PACNS most are found to have another nosologic diagnosis, 2) Not all cases can be definitively categorized despite a vigorous diagnostic approach and 3) Based on such complexity most suspected cases warrant a multidisciplinary approach.
Methods: Of 261 angiograms read at our hospital between 1986 and 1997, 32 were consistent with CNSV.
http://www.vasculiti.it/sandiego3.htm   (597 words)

  
 Title: font: times; size: 18 point; style: plain; justified: center; capitalization: first word and Names only
In systemic investigation, no underlying cause for vasculitis could be found.
Since we could not find features of systemic vasculitis, the patient’s lesions responded to corticosteroid treatment and neuropathological investigation revealed no lymphoma.
We concluded that the most probable diagnosis would be PACNS.
http://kenes.com/stroke5/Abstracts/70.htm   (207 words)

  
 nradnormal.html
Case #381: MRI brain, 2/21/96, 2/28/96, and Cerebral Angiogram, 2/22/96: CNS Vasculitis with evidence of ischemic infarction in the right and left frontal lobes.
Pathologic evaluation revealed evidence of focal necrosis(stroke/infarct), but no evidence of vasculitis.
Immediately following the brain biopsy, while still in the recovery room, she experienced sudden onset right hemiparesis and transcortical motor type aphasia.
http://www.uiowa.edu/~c064s01/nr381.htm   (716 words)

  
 FUNGUS INFECTIONS IN CNS
This is classically found in mucormycosis where blackish necrotic areas are seen in the palate and nasal turbinates.
Vasculitis leading on to thrombosis and mycotic aneurysms in common involving proximal larger arteries.
(b) Aspergillosis or mucormycosis may produce sudden onset of deficit due to vasculitis.
http://www.thamburaj.com/Fungus.htm   (979 words)

  
 Biopsy-proven cerebral vasculitis associated with cocaine abuse -- Krendel et al. 40 (7): 1092 -- Neurology
showed vasculitis involving small vessels in both patients.
We report cerebral vasculitis in 2 cocaine users who developed symptoms
Biopsy-proven cerebral vasculitis associated with cocaine abuse -- Krendel et al.
http://www.neurology.org/cgi/content/abstract/40/7/1092   (395 words)

  
 Vasculitis
John L. Bezzant, M.D. More severe damage to capillary sized vessels allows a significant amount of red blood cells and fluid to leak into the surrounding dermis, and this condition is called vasculitis.
http://www-medlib.med.utah.edu/kw/derm/pages/ph10_2.htm   (33 words)

  
 Holistic Health Encyclopedia - L
Probiotics sometimes help people who suffer from Leaky Gut Syndrome.
Diseases in this category include lupus, alopecia areata, rheumatoid arthritis, polymyalgia rheumatica, multiple sclerosis, fibromyalgia, chronic fatigue syndrome, Sjogren's syndrome, vitiligo, thyroiditis, vasculitis, Crohn's disease, ulcerative colitis, urticaria (hives), diabetes and Raynaud's disease.
http://www.findhealer.com/glossary/L.php3   (6915 words)

  
 Cleveland Clinic Journal of Medicine
Possible Role of ANCA and AECA in Select Forms of Systemic Vasculitis
Immune Predisposition and Infectious Etiology of Systemic Vasculitis
Known Infectious Causes of Vasculitis in Man – Stanley J. Naides.........................SII-15
http://www.ccjm.org/toc/vasculitis.htm   (416 words)

  
 Henoch-Schonlein Purpura (HSP) Vasculitis - 2
Henoch-Schonlein Purpura (HSP) Vasculitis - Medial Ankle - Note retiform purpura.
Direct immunofluorescence (DIF) showed deposits of IgA about dermal vessels.
http://tray.dermatology.uiowa.edu/HSPurp02.htm   (45 words)

  
 Leukocytoclastic Vasculitis - 1
Leukocytoclastic Vasculitis - Lower Legs - (Coincidental Psoriasis - Knees)
http://tray.dermatology.uiowa.edu/LCVasc001.htm   (34 words)

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