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| | CDC Smallpox Information on Live Virus Vaccines & Vaccinia |
 | | People most likely to have side effects are people who have, or even once had, skin conditions, (especially eczema or atopic dermatitis) and people with weakened immune systems, such as those who have received a transplant, are HIV positive, or are receiving treatment for cancer. | | | This way, vaccinia can spread to other parts of the body or to other individuals. | | | In the past, spreading to other parts of the vaccine recipients’ body was the more common form of inadvertent inoculation. |
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http://www.bt.cdc.gov/agent/smallpox/vaccination/live-virus.asp
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| | Smallpox Vaccination and Adverse Reactions |
| | Smallpox vaccine is administered by using the multiple-puncture technique with a bifurcated needle (6). | | | Prophylactic therapy with these drugs might also be considered to prevent spread to the conjunctiva and cornea if vaccinia lesions are present on the eyelid, including if near the lid margin, or adjacent to the eye. | | | When evaluating a skin or other condition consistent with vaccinia, a history of smallpox vaccination and exposure to a household or close contact who has been vaccinated recently will often provide a source of the virus. |
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http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5204a1.htm
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| | eMedicine - Vaccinia : Article by Howard L Kaufman, MD |
| | A bifurcated needle is used to apply the vaccine by pressing in and out of the skin of the upper deltoid region of the arm 5 times for a primary vaccination and 15 times for a revaccination. | | | A recombinant vaccinia virus expressing the rabies glycoprotein was effective in preventing rabies in wild foxes. | | | The effectiveness of vaccinia virus as a vaccine was of paramount importance in this effort. |
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http://www.emedicine.com/med/topic2356.htm
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| | Vaccinia (Progressive vaccinia/vaccinia necrosum) & Eczema vaccinatum |
| | Progressive vaccinia (vaccinia necrosum), which was fatal, in a child with an imunodeficiency. | | | Ocular vaccinia should be treated aggressively with a topical antiviral drug under close ophthalmological supervision. | | | Progressive vaccinia (vaccinia necrosum) in patient with chronic granulocytic leukemia. |
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http://www.whale.to/v/vaccinia-necrosum.html
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| | CNN.com - Vaccinated people can transmit vaccinia virus - Oct. 15, 2002 |
| | And the disease was more likely to be spread to people with a history of eczema even though they had no active skin lesions. | | | The researchers, led by Dr. John Neff, a former researcher with the Center for Disease Control and Prevention's Smallpox Eradication Program, discussed what they found in a commentary in this week's Journal of the American Medical Association released today. | | | The authors theorize that's likely due to the spread of HIV and wider use of drugs to suppress the immune system for cancer patients and organ transplant recipients, for example. |
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http://archives.cnn.com/2002/HEALTH/conditions/10/15/smallpox.danger
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| | Title of Invention: Vaccinia virus containing DNA s equences encoding herpesvirus glycoproteins |
| | The contribution of the individual glycoproteins in eliciting a protective immune response is not completely understood. | | | Expression of these glycoproteins in a heterologous system, such as vaccinia, has allowed some of these parameters to be analyzed. | | | PRV gp50 was manipulated to be expressed under the control of an early/intermediate vaccinia virus promoter, I3L (187). |
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http://www.nal.usda.gov/bic/Biotech_Patents/1994patents/05338683.html
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| | Smallpox (Vaccinia) Vaccine Injury Table |
| | Survivor of a smallpox vaccine recipient or a vaccinia contact who died as a direct result of a medical injury covered by this Program, or | | | prior to contracting vaccinia, was accidentally inoculated by a smallpox vaccine recipient or a contact of such a person. | | | Individuals who have injuries not in the Table injuries also may be considered eligible for benefits if their injuries can be shown to be the direct result of the smallpox vaccine, other covered countermeasures or vaccinia. |
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http://www.hrsa.gov/smallpoxinjury
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| | VACCINIA VIRUS |
| | Progressive vaccinia is a severe, potentially fatal illness characterized by progressive necrosis at the site of vaccination. | | | Accidental infection of some part of the body away from the inoculation site was the most common complication that arose from vaccination with vaccinia. | | | Postvaccinal encephalitis usually occurred in patients over the age of two. |
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http://www.stanford.edu/group/virus/pox/2000/vaccinia_virus.html
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| | Vaccinia Virus |
| | The latter usually only occurs in the immunosuppressed or those with multiple skin lesions as would occur with severe eczema. | | | Some people think that it is a recombinant of smallpox and cowpox, while others think that it may be a derivative of horsepox, a virus that no longer exists (if it ever did). | | | The only diseases vaccinia causes are complications of vaccination, post vaccinal encephalitis and progressive (spreading) vaccinia. |
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http://medinfo.ufl.edu/year2/mmid/bms5300/bugs/vacvirus.html
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| | Vaccinia Information from Drugs.com |
| | Generic Name: Vaccinia Immune Globulin Intravenous (Human) (VIGIV) | | | The FDA has approved Vaccinia Immune Globulin Intravenous (VIGIV) -- the first intravenous human plasma-derived product available to treat certain rare complications of smallpox vaccination. | | | For more information, see Vaccinia Immune Globulin Intravenous (Human) Package Insert |
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http://www.drugs.com/vaccinia.html
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| | vaccinia |
| | an acute infection caused by inoculation with vaccinia virus as a prophylactic against smallpox, characterized by localized pustular eruptions. |
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http://www.infoplease.com/dictionary/vaccinia
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| | Vaccinia virus - Material Safety Data Sheets (MSDS) |
| | FIRST AID/TREATMENT: Vaccinia immune globulin and methisazone may be of value in treating complications | | | MODE OF TRANSMISSION: Virus may be transmitted to contacts of individuals who have been vaccinated recently | | | Newly discovered hazards are frequent and this information may not be completely up to date. |
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http://www.phac-aspc.gc.ca/msds-ftss/msds160e.html
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| | MedlinePlus Medical Encyclopedia: Smallpox |
| | Vaccinia immune globulin (antibodies against a disease similar to smallpox) may help shorten the disease. | | | Sometimes antibiotics are given for secondary infections that may occur. | | | If a diagnosis of smallpox were made, exposed persons would need to be isolated immediately. |
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http://www.nlm.nih.gov/medlineplus/ency/article/001356.htm
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| | Vaccinia (smpox) Scarf #3402S Green/Purple |
| | Vaccinia virus, a less dangerous relative of variola, forms the basis for the smallpox vaccine which was used to accomplish one of historyâs great public health achievements, global elimination of smallpox. | | | Our design is dedicated to the courageous U.S. led WHO team instrumental in this effort. |
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http://www.5clickstore.com/iawareables/product.cfm?ProductID=198
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| | progressive vaccinia - definition of progressive vaccinia by the Free Online Dictionary, Thesaurus and Encyclopedia. |
| | progressive vaccinia - a severe or even fatal form of vaccinia that occurs mainly in persons with an immunological deficiency; characterized by progressive enlargement of the initial lesion | | | This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. | | | vaccina, vaccinia, variola vaccina, variola vaccine, variola vaccinia - a local infection induced in humans by innoculation with the virus causing cowpox in order to confer resistance to smallpox; normally lasts three weeks and leaves a pitted scar |
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http://www.thefreedictionary.com/progressive+vaccinia
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| | swf001cso: Morphological changes that result from vaccinia-virus infection of BS-C-1 cells |
| | The infection of BS-C-1 cells [African green monkey (Cercopithecus aethiops) kidney cells] with vaccinia virus induces two distinct forms of cell motility: (1) cell migration, which is maximal 8–15 h post infection (hpi), and (2) the formation of long neurite-like projections, which form 15–24 hpi, when cell migration has reduced. |
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http://www-ermm.cbcu.cam.ac.uk/9900068Xh.htm
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