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Topic: VLDL

Ads by Google      Metabolism of VLDL is increased in streptozotocin-induced diabetic rat hearts -- Sambandam et al. 278 (6): 1874 -- AJP ... In vitro lipolysis of VLDL by bovine and rat LPL. conditions to study lipolysis of VLDL by LPL, TG in control VLDL Values are averages of 2 separate experiments carried out in triplicate. http://ajpheart.physiology.org/cgi/content/full/278/6/H1874   (5278 words)      Increased hepatic VLDL secretion, lipogenesis, and SREBP-1 expression in the corpulent JCR:LA-cp rat -- Elam et al. 42 ... VLDL was greater in the cp/cp rat, as was the apolipoprotein of VLDL in the perfusate of livers from cp/cp rats; however, Secretion of VLDL associated apolipoproteins was greater in http://www.jlr.org/cgi/content/full/42/12/2039   (6526 words)      Regulation of Very-Low-Density Lipoprotein Receptor in Hypertrophic Rat Heart -- Masuzaki et al. 78 (1): 8 -- ... Northern blot analysis of VLDL receptor (VLDLR) and LPL mRNAs in ventricles of SHR-SP and WKY rats. Northern Blot Analysis of VLDL Receptor and LPL mRNAs in Ventricles of SHR-SP and WKY Rats The ventricular LPL mRNA level in 4-week-old SHR-SP was 65% of that in 4-week-old WKY rats, and by 13 weeks was http://circres.ahajournals.org/cgi/content/full/78/1/8   (4027 words)      VLDL activation of plasminogen activator inhibitor-1 (PAI-1) expression: involvement of the VLDL receptor -- Nilsson et ... human VLDL and chylomicron remnants (12) (17) (32) (49). This response to VLDL could be completely prevented by the receptor-associated The results were derived from 3 experiments, all performed in triplicate. http://www.jlr.org/cgi/content/full/40/5/913   (4938 words)      Effects of Growth Hormone (GH) Replacement Therapy on Very Low Density Lipoprotein Apolipoprotein B100 Kinetics in ... and the kinetic behavior of VLDL subfractions can be deduced The FSR of VLDL is subject to an intrahepatic VLDL apoB clearance rate observed after GH replacement therapy http://jcem.endojournals.org/cgi/content/full/84/1/307   (5265 words)      Differences in the relation of obesity to serum triacylglycerol and VLDL subclass concentrations between black and ... Six VLDL subclasses were quantified with the use of these techniques. The number of subjects in the current analysis was substantially The subsequent analyses focused on the 916 children examined http://www.ajcn.org/cgi/content/full/75/5/827   (3947 words)      Effects of Fish Oil on Oxidation Resistance of VLDL in Hypertriglyceridemic Patients -- Hau et al. 16 (9): 1197 -- ... PUFAs, affects the resistance of VLDL to oxidation. in the VLDL lag time tended to correlate with the change in contribute to the change in the oxidation resistance of VLDL. http://atvb.ahajournals.org/cgi/content/full/16/9/1197   (4170 words)      Uptake of Type III Hypertriglyceridemic VLDL by Macrophages Is Enhanced by Oxidation, Especially After Remnant ... Values are mean±SEM for number of experiments indicated for each incubation condition. oxidation of human VLDL as assessed by increases in REMs, The oxidation of VLDL from normolipidemic subjects after 24 http://atvb.ahajournals.org/cgi/content/full/17/9/1707   (5863 words)      Differential Reactivity of Two Homogeneous LDL-Cholesterol Methods to LDL and VLDL Subfractions, as Demonstrated by ... Differential Reactivity of Two Homogeneous LDL-Cholesterol Methods to LDL and VLDL Subfractions, as Demonstrated by Ultracentrifugation and HPLC -- Usui et al. We do not think that part of the VLDL fraction of homogeneous LDL-cholesterol methods to other VLDL and LDL http://www.clinchem.org/cgi/content/full/48/11/1946   (3874 words)      The Atherogenic Lipoprotein Lp(a) is Internalized and Degraded in a Process Mediated by the VLDL Receptor -- Argraves ... Analysis of apo(a) from Lp(a) isoforms isolated from subjects by immunoblot analysis after SDS-PAGE. is expressed in the endothelium, it seems likely that the VLDL The specificity of this interaction was demonstrated when RAP, http://www.jci.org/cgi/content/full/100/9/2170   (8023 words)      Contributions of De Novo Synthesis of Fatty Acids to Total VLDL-Triglyceride Secretion during Prolonged ... Kissebah, A.H. Alfarsi, and P.W. Adams (1981) Integrated regulation of very low density lipoprotein triglyceride and apolipoprotein-B kinetics in man: normolipidemic subjects, familial hypertriglyceridemia and familial combined hyperlipidemia. This approach is justified by the fact that 15, 50, 51, 52, 53) or did not affect (11, 54) VLDL http://www.jci.org/cgi/content/full/98/9/2008   (7328 words)      Phosphatidylinositol 3-Kinase and Calcium-Activated Transcription Pathways Are Required for VLDL-Induced Smooth Muscle ... Each point represents the mean of 3 to 6 independent experiments. Thus, we analyzed the effect of VLDL (1 mmol/L triglycerides) The NFAT isoform expressed in rat aortic SMCs was determined http://circres.ahajournals.org/cgi/content/full/92/10/1115   (4488 words)      Lipids Online Slides: VLDL, lipid metabolism, mechanism of action ATP III: New Approaches in Identifying and Treating High-Risk Patients (Steven Haffner, MD) Combination Lipid-Altering Drug Therapy with Statins (Harold Bays, MD, FACP) Therefore, ezetimibe reduces the flux of cholesterol from the intestine to the liver. http://www.lipidsonline.org/slides/slide01.cfm?q=VLDL   (1399 words)      Effects of a low-fat, high-carbohydrate diet on VLDL-triglyceride assembly, production, and clearance -- Parks et al. ... Zilversmit, D.B. The design and analysis of isotope experiments. second aliquot of VLDL was subjected to an additional ultracentrifugation Reduced susceptibility of LDL from patients participating in an intensive atherosclerosis treatment program. http://www.jci.org/cgi/content/full/104/8/1087   (6956 words)      Lipopolysaccharide (LPS)-Binding Protein Mediates LPS Detoxification by Chylomicrons -- Vreugdenhil et al. 170 (3): ... The experiment shown is representative of three separate experiments. Lipoproteins were isolated from human serum by ultracentrifugation. VLDL were isolated from pooled fresh human sera (six healthy http://www.jimmunol.org/cgi/content/full/170/3/1399   (4952 words)      The Carboxyl-terminal Domain of Receptor-associated Protein Facilitates Proper Folding and Trafficking of the Very Low ... pathway, we analyzed the kinetics of the VLDL receptor trafficking trafficking of the VLDL receptor within the early secretory pathway. was further studied using an anchor-free, soluble VLDL receptor. http://www.jbc.org/cgi/content/full/274/36/25877   (4906 words)      Healthopedia.com - VLDL (Very-Low-Density Lipoprotein) The test can also monitor how well medications prescribed to lower lipids are working. VLDL is usually measured with other lipoproteins, such as HDL and LDL. The level of VLDL can help assess a person's risk of atherosclerosis, or clogged arteries. http://www.healthopedia.com/vldl   (259 words)      Effect of weight loss on VLDL-triglyceride and apoB-100 kinetics in women with abdominal obesity -- Mittendorfer et al. ... lipoprotein subfraction was similar in lean (6 ± 1% VLDL, 6 ± apoB-100 metabolic pathways that may affect VLDL particle methods used to assess VLDL kinetics, which did not account for http://ajpendo.physiology.org/cgi/content/full/284/3/E549   (5342 words)      Estrogen Induction of VLDLy Assembly in Egg-Laying Hens -- Walzem et al. 129 (2): 467 -- Journal of Nutrition Thus, under typical VLDL metabolic conditions, apoB-LP with diameters VLDL cholesteryl ester:triacylglycerol varied from 1.8 to 2.9 VLDL from this tissue would continue to supply those tissues expressing http://nutrition.org/cgi/content/full/129/2/467S   (3686 words)      VLDL, Apolipoproteins B, CIII, and E, and Risk of Recurrent Coronary Events in the Cholesterol and Recurrent Events ... However, subordinance of apoE to the actions of apoCIII does in VLDL and LDL in influencing coronary events in humans. of VLDL and the apoE and apoCIII concentrations in VLDL+LDL http://circ.ahajournals.org/cgi/content/full/102/16/1886   (4030 words)      Triglycerides and VLDL Related content from HighBeam Research on: Triglycerides and VLDL Effects of acute hyperinsulinemia on VLDL triglyceride and VLDL ApoB production in normal weight and obese individuals. VLDL triglyceride kinetics in Wistar fatty rats, an animal model of NIDDM: effects of dietary fructose alone or in combination with pioglitazone.(non-insulin-dependent diabetes mellitus) (Diabetes) http://www.infoplease.com/ipa/A0873275.html   (279 words)      The Effect of a Six-Month Exercise Program on Very Low-Density Lipoprotein Apolipoprotein B Secretion in Type 2 ... P < 0.05) with no change in fractional catabolic rate. This work was supported by a grant from the British Heart Foundation program reduces VLDL apoB pool size, which may be due to a decrease http://jcem.endojournals.org/cgi/content/abstract/89/2/688   (470 words)      Hypertriglyceridemic VLDL Downregulates Tissue Plasminogen Activator Gene Transcription Through cis-Repressive ... For example, prior studies in our laboratory have demonstrated Hypertriglyceridemic VLDL Downregulates Tissue Plasminogen Activator Gene Transcription Through cis-Repressive Region(s) in the Tissue Plasminogen Activator Promoter in Cultured Human Endothelial Cells -- Tabengwa et al. VLDLs used had Svedberg flotation rates of 100 to 400. http://atvb.ahajournals.org/cgi/content/full/20/6/1675   (4544 words)      VLDL-triglyceride production after alcohol ingestion, studied using [2-13C1] glycerol -- Siler et al. 39 (12): 2319 -- ... BIA, bioelectrical impedance analysis; LBM, lean body mass; acids to the VLDL particle, we have expressed the changes that VLDL were isolated by ultracentrifugation as described previously http://www.jlr.org/cgi/content/full/39/12/2319   (5445 words)      Lipoproteins.net: Information on HDL, LDL, VLDL, cholesterol and atherosclerosis Adipose tissue, heart and muscle do most of the metabolism. The majority of VLDL are derived from the liver and represent the transport mechanisms for triacylglycerol from the liver to other tissues. The mechanism of manufacture and release is remarkably similar to the particulate secretion of chylomicrons in the intestine. http://www.lipoproteins.net   (891 words)      ► VLDL Increased levels of VLDL are associated with atherosclerosis and coronary heart disease. VLDL is often called "bad cholesterol" because it deposits cholesterol on the walls of arteries. On the contrary, high density lipoprotein (HDL), sometimes referred to as "good cholesterol," seems to protect against blood vessel and heart diseases. http://www.umm.edu/ency/article/003494.htm   (174 words)      VLDL receptor polymorphism, cognitive impairment, and dementia -- Helbecque et al. 56 (9): 1183 -- Neurology VLDL receptor polymorphism, cognitive impairment, and dementia -- Helbecque et al. http://www.neurology.org/cgi/content/abstract/56/9/1183   (348 words)      Regulation of the Ligand Binding Activity of the Human Very Low Density Lipoprotein Receptor by Protein Kinase ... Differences in the tissue distribution of the LDL and VLDL receptors also suggest non-overlapping physiologic functions. Measurement of VLDL Receptor Expression by Ligand or Immunoblotting-- Expression of functional VLDL-R was assessed by ligand blotting using RAP or u-PA:PAI-1 complexes as ligands (16, 19). We also examined the effect of PMA on the binding of human VLDL to THP-1 cells. http://www.jbc.org/cgi/content/full/276/1/555   (6724 words)      Effect of sex and obesity on basal VLDL-triacylglycerol kinetics -- Mittendorfer et al. 77 (3): 573 -- American Journal ... by increased transfer of HDL cholesteryl esters to VLDL (7). Lewis GF, Uffelman KD, Szeto LW, Steiner G. Effects of acute hyperinsulinemia on VLDL triglyceride and VLDL apoB production in normal weight and obese individuals. Immediately after the completion of the study, VLDL was isolated http://www.ajcn.org/cgi/content/full/77/3/573   (3902 words)      Hepatic Catabolism of Remnant Lipoproteins: Where the Action Is -- Havel and Hamilton 24 (2): 213 -- Arteriosclerosis, ... LDLR caused by enhanced uptake of VLDL remnants. rates of VLDL clearance were halved in mice expressing apo E4 as compared with those observed in mice expressing apo E3. The lipoproteins are transported within the maturing endosomes toward the biliary (apical) pole of the cells, forming multivesicular bodies (MVB) (late endosomes), whereas the excess surface membrane resulting from endosome-fusion forms recycling endosomes that carry the receptors back to the basolateral surface of the cell (modified from Figure 1 in Havel RJ, Hamilton RL. http://www.atvbaha.org/cgi/content/full/24/2/213   (2400 words)      Very low density lipoprotein - Wikipedia, the free encyclopedia VLDL is prone to accelerate atherosclerosis, and is elevated in a number of diseases and metabolic states. This page was last modified 01:50, 7 August 2005. It is assembled in the liver from cholesterol and apolipoproteins. http://en.wikipedia.org/wiki/Very_low_density_lipoprotein   (82 words)      Atorvastatin Treatment Induced Peroxisome Proliferator-Activated Receptor alpha Expression and Decreased Plasma ... The effect of HMG-CoA reductase inhibitors on cholesterol homeostasis is complex and may not be confined to the blockage of Effect of atorvastatin treatment on key factors involved in hepatic lipid synthesis and VLDL assembly Park J, Lemieux S, Lewis GF, Kuksis A and Steiner G (1997) Chronic exogenous insulin and chronic carbohydrate supplementation increase de novo VLDL triglyceride fatty acid production in rats. http://jpet.aspetjournals.org/cgi/content/full/302/1/232   (4489 words)      Compared with saturated fatty acids, dietary monounsaturated fatty acids and carbohydrates increase atherosclerosis and ... In other studies, we have shown that cholesterol feeding of apoEKO trafficking of liver cholesterol/CE involved in VLDL production. Finally, because hepatic apo E production has been found to increase http://www.pnas.org/cgi/content/full/98/23/13294   (4089 words)      Triacylglycerol Hydrolase Is Localized to the Endoplasmic Reticulum by an Unusual Retrieval Sequence where It ... this lipid once it is associated with VLDL. Triacylglycerol Hydrolase Is Localized to the Endoplasmic Reticulum by an Unusual Retrieval Sequence where It Participates in VLDL Assembly without Utilizing VLDL Lipids as Substrates -- Gilham et al. for vectored movement of TGs onto developing VLDL in the ER as TGH may mobilize TG for VLDL assembly, but will not access http://www.molbiolcell.org/cgi/content/abstract/16/2/984   (351 words)      beta -Migrating Very Low Density Lipoprotein (beta VLDL) Activates Smooth Muscle Cell Mitogen-activated Protein (MAP) ... VLDL induces expression of egr-1 and c-fos mRNA. VLDL) Activates Smooth Muscle Cell Mitogen-activated Protein (MAP) Kinase via G Protein-coupled Receptor-mediated Transactivation of the Epidermal Growth Factor (EGF) Receptor beta -Migrating Very Low Density Lipoprotein (beta VLDL) Activates Smooth Muscle Cell Mitogen-activated Protein (MAP) Kinase via G Protein-coupled Receptor-mediated Transactivation of the Epidermal Growth Factor (EGF) Receptor. http://www.jbc.org/cgi/content/abstract/276/33/30579   (522 words)      Insulin Inhibits the Maturation Phase of VLDL Assembly via a Phosphoinositide 3-Kinase--Mediated Event -- Brown and ... Insulin Inhibits the Maturation Phase of VLDL Assembly via a Phosphoinositide 3-Kinase--Mediated Event -- Brown and Gibbons 21 (10): 1656 -- Arteriosclerosis, Thrombosis, and Vascular Biology http://atvb.ahajournals.org/cgi/reprint/21/10/1656   (26 words)      Lipid-dependent Bidirectional Traffic of Apolipoprotein B in Polarized Enterocytes -- Morel et al. 15 (1): 132 -- ... Olofsson, S.O., Stillemark-Billton, P., and Asp, L. Intracellular assembly of VLDL: two major steps in separate cell compartments. http://www.molbiolcell.org/cgi/content/full/15/1/132   (7927 words)      CiteULike: csainsbury's vldl Recent papers added to csainsbury's library classified by the tag vldl. posted to endothelium fattyacids ffa nfkb vldl by csainsbury as http://www.citeulike.org/user/csainsbury/tag/vldl   (57 words)

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