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| | Cecil Textbook of Medicine : /> |
 | | Chronic, low-titer VDRL reactivity after therapy is much more common in cases of late syphilis and should not be viewed with alarm. | | | Patients with late latent syphilis should be examined also at 24 months after therapy; if CSF was not examined before therapy, a lumbar puncture should be done before discharge to rule out inadequately treated asymptomatic neurosyphilis. | | | In about 85% of patients with early (i.e., primary, secondary, or early latent) syphilis, quantitative VDRL titers become nonreactive in 12 to 24 months after therapy. |
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http://www.merckmedicus.com/ppdocs/us/common/cecils/chapters/349_014.htm
(2160 words)
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| | CHAPTER 21 |
| | Its specificity is no better than that of the VDRL in healthy (99 percent) and sick (85 percent) patients, contrary to widespread belief. | | | If both tests are negative and the patient has a highly suspicious lesion (such as a painless genital ulcer), each can be repeated. | | | The specificity is about 99 percent and 84 percent in healthy and sick persons, respectively. |
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http://cpmcnet.columbia.edu/texts/ambulatory/21RPR.html
(1771 words)
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| | Comparative Study of VDRL and TPHA and their Complementary Roles in Serodiagnosis of Syphilis |
| | Moreover TPHA should be done in blood transfusion products as VDRL may be weak positive or may be prozone phenomenon and be falsely interpreted as negative. | | | Three patients who were HIV +ve, out of the three one was found to have TPHA +ve (may be false positive) and two (2) were VDRL positive in lower titre (1:4). | | | Again the TPHA may be useful in concluding whether the infant should be treated or not. |
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http://www.bhj.org/journal/2002_4401_jan/org_36.htm
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| | Evidence of seropersistent VDRL test reactivity in an elderly Treponema pallidum-infected population |
| | Nevertheless, it would be more correct to assess the old population of the infected with regard to previous treatment, or no treatment, by means of the Bayes' theorem-based procedure which we used in the No. 3 (1997) issue of this review, presenting the results of the first part of the same study (5). | | | Nevertheless, a growing trend in the number of VDRL nonreactors among the infected observed over 22 years points to the fact that in the past few years the treatment of syphilis has become increasingly effective. | | | Inserting our data on VDRL positive tests amounting to 49% (VDRL sensitivity) of all the infected (TPHA positives) into the Bayes theorem-based formula (5), together with VDRL sensitivity data for treated (1%) and untreated (70%) yielded a proportion of 0.7, an indication that 70% of our infected subjects had probably not been treated. |
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http://www.mf.uni-lj.si/acta-apa/acta-apa-00-1/muic.html
(2017 words)
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| | Lab News, Mar 1995c, Department of Laboratory Medicine at Yale |
| | This usually includes a thorough physical examination for evidence of congenital syphilis and a quantitative nontreponemal serological test (VDRL or RPR) performed on infant serum (NOT cord blood). | | | On this basis, one could argue for treatment of all infants whose mothers at delivery had a positive VDRL, confirmed with a positive FTA-ABS. | | | The Laboratory Medicine resident will explain the procedure for sending the sample under these circumstances. |
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http://info.med.yale.edu/labmed/labnews/mar1995c.html
(1366 words)
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| | 2.1.4.2 Serological Testing |
| | RPR titers are generally higher than VDRL titers, and are not directly comparable to VDRL titers to monitor response to therapy. | | | Nontreponemal tests (RPR, VDRL) are used to screen for syphilis and assess response to treatment. | | | Whereas serologically-defined failure may occur in up to 20% of HIV+ patients, clinically-defined failure has been reported but is thought to be much less common. |
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http://www.bu.edu/cme/std/sec02/sec02-1.4.2.shtml
(972 words)
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| | False Positive (Can This Marriage Be Saved?) |
| | Both of these tests were developed using blood collected from the unfortunate subjects of the infamous "Tuskegee experiment." This study, conducted by the PHS between 1932 and 1972, followed a group of about 400 poor African-American men from rural Alabama who were infected with syphilis. | | | If the VDRL is positive, clinical laboratories will routinely perform the confirmatory FTA test. | | | Guerrero's case, his VDRL was weakly positive and the FTA was negative. |
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http://www.sfgate.com/cgi-bin/article.cgi?file=/gate/archive/2003/05/29/dre.DTL&type=printable
(893 words)
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| | SYPHILIS |
| | Quantitative VDRL at 1, 2, and 3 months and at 3-monthly intervals thereafter should be measured until a satisfactory serological response to treatment. | | | Check VDRL (quantitative) on baby and mother, FTA IgM on baby | | | In some of these patients, both VDRL, FTA or TPHA may be negative, while some have unusual high VDRL titre. |
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http://www.hkmj.org.hk/skin/syphilis.htm
(2131 words)
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| | Neurosyphilis |
| | Persistent CSF pleocytosis and no change in CSF VDRL or serum VDRL titer 6 months after therapy in HIV infected patient | | | RPR, VDRL may be negative in late stage | | | Symptomatic meningitis: clinical meningitis, may develop cranial nerve abnormalities, hydrocephalus. |
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http://neuroland.com/id/neurosyph.htm
(285 words)
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| | VDRL, Cerebrospinal Fluid |
| | A positive VDRL in a spinal fluid uncontaminated by serum is essentially diagnostic of neurosyphilis. | | | However, a negative test may occur in 30% of patients with tabes dorsalis. | | | The CSF VDRL may take years to become nonreactive after adequate therapy. |
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http://www.labcorp.com/datasets/labcorp/html/chapter/mono/se023300.htm
(86 words)
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| | Specialty Laboratories ::: we help doctors help patients |
| | The MHA-TP and FTA-ABS, in contrast to the VDRL, remain positive for life in ~85% of patients who are successfully treated | | | makes them less useful than the VDRL for monitoring treatment. | | | In a patient with a serum VDRL of 1:256 or less, a traumatic lumbar puncture will not result in a false-positive CSF VDRL unless there is sufficient contamination of CSF with blood to produce a visibly bloody CSF. |
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http://www.specialtylabs.com/books/display.asp?id=455
(2426 words)
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| | VDRL |
| | If an individual is suspected of having brain involvement with syphilis (neurosyphilis), the VDRL test may be performed on spinal fluid. | | | However, the body does not always produce reagin specifically in response to the syphilis bacteria, so the test is not always accurate. | | | VDRL is a screening test for syphilis that measures antibodies called reagins that can be produced by Treponema pallidum, the bacteria which causes syphilis. |
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http://www.pennhealth.com/ency/article/003515.htm
(631 words)
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| | Re: Will one still test 'reactive' to VDRL long after having been treated? |
| | If it is positive then the possibility that the person has syphilis is more likely. | | | Interpreting the VDRL can be a little confusing because there are false positive test due to a variety of other condition as well as other spirochete infections. | | | A person who was treated 10 years ago and now has a rective VDRL should have a FTA and a quantitative VDRL done. |
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http://www.madsci.org/posts/archives/dec97/876618923.Mi.r.html
(439 words)
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| | CSF VDRL test Medical Reference - MedicineOnline.com |
| | Because this test has a high rate of false negatives, a negative test does not rule out neurosyphilis. | | | The CSF-VDRL test is used to diagnose syphilis in the brain or spinal cord. | | | Alternative Medicine > Fasting and Cleansing > CSF VDRL test |
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http://www.medicineonline.com/reference/Alternative_Medicine/Fasting_and_Cleansing/CSF_VDRL_test
(492 words)
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| | Forum on Understanding Your Labs: vdrl |
| | Dear Doctor, What is meant by VDRL non reactive. | | | Questions pertaining to a specific case; requests for diagnosis, medical advice, or second opinion; or requests for opinions about untested alternative therapies will generally not be answered. | | | A VDRL is a nonspecific test for syphillis. |
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http://www.thebody.com/Forums/AIDS/Labs/Current/Q154141.html
(323 words)
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| | OJHAS: The Online Journal of Health and Allied Sciences |
| | In the sexually transmitted disease clinic, syphilis serology is a basic screening test. | | | Biological false reactive VDRL test among the HIV-infected patients: A note on its prevalence | | | Abstract: Serological tests for syphilis may show varying results in association with HIV infection.Thus care should be taken to interpret these results.. |
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http://www.ojhas.org/latest.htm
(581 words)
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| | Reliability of VDRL test |
| | Therefore, a negative test means you don't have syphilis. | | | In light of the fact that I had no other symptoms that could be associated with syphilis and a negative test result do I need to worry about this further? | | | I have not worried about this until I read an article which stated that the VDRL test is unreliable in early stages of syphilis. |
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http://www.medhelp.org/perl6/Dermatology/messages/33826.html
(231 words)
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| | s010402a - CSF Evaluation of Neurosyphilis |
| | Asymptomatic neurosyphilis, diagnosed on the basis of a reactive VDRL test of the CSF, was present in one (2%) of 49 patients. | | | Previous therapy for syphilis was not associated with lower serum VDRL reactions, neurologic symptoms and signs, or cerebrospinal fluid findings. | | | Thirty-eight of the remaining patients were diagnosed as having active neurosyphilis. |
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http://www.emory.edu/WHSCL/grady/amreport/litsrch00/s010402a.html
(1424 words)
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| | VDRL test definition - Medical Dictionary definitions of popular medical terms |
| | A negative (nonreactive) VDRL is compatible with a person not having syphilis, but in the early stages of the disease, the VDRL often gives false negative results. | | | VDRL test: A blood test for syphilis (VDRL stands for Venereal Disease Research Laboratory) that detects an antibody that is present in the bloodstream when a patient has syphilis. | | | Vestibular Balance Disorders - Learn about vestibular balance disorders including the symptoms caused by balance disorders, causes, how balance disorders are evaluated, and treatment |
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http://www.medterms.com/script/main/art.asp?articlekey=9221
(244 words)
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| | p020305b - Neurosyphilis - CSF diagnosis |
| | Discriminant analysis, used on 124 patients, shows that other commonly used laboratory tests can, in combination, identify 87% of patients with neurosyphilis with 94% specificity. | | | We examined the use of the Treponema pallidum hemagglutination (TPHA) index and quantitative tests of CSF by means of microhemagglutination-T. pallidum for diagnosis of neurosyphilis in 58 HIV-infected persons with latent syphilis who had not recently received therapy for syphilis. | | | The CSF VDRL test was positive in 55/60 (91.7%) of samples from patients with neurosyphilis and in none of the controls (0/54). |
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http://www.emory.edu/WHSCL/grady/amreport/litsrch01/p020305b.html
(1054 words)
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| | BD - Diagnostic Systems: VDRL Test Control Serum Set |
| | Nontreponemal tests such as the VDRL are used to screen patient serum, while treponemal tests such as the FTA-ABS are used for confirmation. | | | VDRL Antigen with Buffered Saline is recommended for use in the Venereal Disease Research Laboratory (VDRL) |
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http://www.bd.com/ds/productCenter/235201.asp
(1252 words)
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| | [No title] |
| | A nonreactive VDRL test may indicate that the patient does not have neurosyphilis. | | | However, a negative result can occur in some neurosyphilis patients. | | | A biological false-positive test result is rare in spinal fluid. |
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http://www.michigan.gov/documents/LSGSyphilisVDRL_8280_7.doc
(265 words)
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| | SyphilisVI |
| | Most patients treated for early syphilis will have reversion of RPR and/or VDRL tests to nonreactive within two years. | | | The VDRL (Venereal Disease Research Laboratory) test on CSF is available as a reference service for other laboratories. | | | After treatment, patients with early syphilis should be retested at 3-month intervals for one year or until little or no reaction is detected by quantitive RPR or VDRL. |
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http://www.oregon.gov/DHS/ph/vi/syph.shtml
(958 words)
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| | [No title] |
| | Further, the 3-D VDRL may be constructed for objects which are currently desired to be displayed as well as objects which are not currently desired to be displayed, e. | | | The system and method of the present invention, referred to as the Interactive Media Controller or Integrated Memory Controller (IMC) may be used in any of various types of systems. | | | Therefore, pointer-based VDRL system and method of the present invention reduces the amount of data required to be moved within the system for processing, thus reducing the overall cost while improving the performance of the computer system. |
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http://www.wipo.int/cgi-pct/guest/getbykey5?KEY=99/56249.991104&ELEMENT_SET=DECL
(13869 words)
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| | Syphilis serology and HIV infection in Harare, Zimbabwe. |
| | With both HIV positive and negative sera the negative predictive values of VDRL and RPR were > 99.9% while the positive predictive value for VDRL (30%) was lower than for RPR (39%). | | | All sera from men who were VDRL positive, and a random sample of VDRL negative sera, were tested by RPR, TPHA, and where appropriate FTA-Abs. | | | From the results, men were defined as having no syphilis, active syphilis, incident syphilis, historic syphilis, or giving biological false positive reactions. |
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http://www.aegis.com/aidsline/2000/jun/A0061475.html
(570 words)
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| | Bioline International Official Site (site up-dated regularly) |
| | This study has been undertaken to define the incidence of aPL of different types (LAC, VDRL and ß | | | AIM: The present study was aimed to define the incidence of antiphospholipid antibodies of different types lupus anticoagulant (LAC), venereal disease research laboratory test (VDRL) and ß | | | In the present study VDRL test revealed reactivity in 7 (2.34%) individuals. |
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http://www.bioline.org.br/request?jp02002
(2912 words)
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| | VDRL |
| | Read as nonreactive or negative if you do not have syphilis. | | | Positive VDRL tests are usually followed up by a more specific test (FTA-ABS). | | | The VDRL can also be positive is cases of leprosy, malaria, mononucleosis, lupus, hepatitis A, and pregnancy. |
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http://www.medhelp.org/glossary/new/gls_4361.htm
(75 words)
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| | Medical Laboratory Observer: Answering your questions on routine VDRL on CSF, Zeta Sedimentation Ratio, ... |
| | Because neurosyphilis is infrequently diagnosed in the United States, efficient use of the CSF-VDRL test requires that the patient be seropositive. | | | In general, a CSF specimen should be tested by the VDRL method if the patient has (a) clinical symptoms consistent with syphilis or a history of syphilis, (b) a reactive serum rapid plasma reagin or fluorescent treponemal antibody absorption test, and (c) an abnormal spinal fluid (elevated protein and leukocyte c ount). | | | When the laboratory and ordering physicians agree to use a set of guidelines to determine when a CSF specimen is tested, the result is a more cost-effective approach to screening patients for neurosyphilis. |
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http://www.findarticles.com/p/articles/mi_m3230/is_8_33/ai_78057544
(1363 words)
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| | WONDER STD Document |
| | Treponemal test antibody titers correlate poorly with disease activity and should not be used to assess response to treatment. | | | Sequential serologic tests should be performed using the same testing method (e.g., VDRL or RPR) by the same laboratory. | | | Abnormal results of serologic testing (unusually high, unusually low, and fluctuating titers) have been observed among HIV-infected patients. |
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http://wonder.cdc.gov/wonder/STD/STDG3431.PCW.html
(515 words)
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| | [No title] |
| | After treatment, a constantly falling titer (although not always observed) is regarded as representative of effective treatment, although it may take many years for the test to become nonreactive. | | | CSF VDRL is the only laboratory test for neurosyphilis approved by the Center for Diseases Control, but it lacks diagnostic sensitivity. | | | Patients with reactive CSF VDRL results are reported to the City of Chicago Board of Health. |
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http://www.rush.edu/webapps/rml/RMLTestEntryDtl.jsp?id=3226
(210 words)
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| | Texas Department of State Health Services - Reagin Based Flocculation Assays |
| | The VDRL antigen forms flocculates when combined with lipoidal antibodies in cerebrospinal fluid from syphilis patients. | | | Rapid Plasma Reagin Card (RPR) and Venereal Disease Research Laboratory (VDRL) tests are two examples of reagin tests used in the Serology Branch. | | | The VDRL tests are slide microflocculation tests that use an antigen containing cardiolipin, lecithin and cholesterol. |
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http://www.dshs.state.tx.us/lab/serology_floc.shtm
(195 words)
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| | VDRL |
| | About>Health & Fitness>Healthcare Center> Women's Health> STD Tests> VDRL |
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http://adam.about.com/encyclopedia/003515.htm
(558 words)
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| | Bioline International Official Site (site up-dated regularly) |
| | High expression levels were achieved using a 58 aa sequence of human interleukin-2 as stabilizer. | | | The ELISA developed with this electroeluted antigen showed 99.2% of specificity for the VDRL- samples and 100% sensitivity with VDRL+ samples. | | | A of study of this recombinant TmpA by ELISA against a panel of VDRL+ and VDRL- sera revealed high sensitivity and specificity, indicating that this antigen is a good option for the diagnosis of syphilis. |
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http://www.bioline.org.br/request?ba95036
(430 words)
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| | Cerebrospinal fluid treponemal antibodies in untreated early syphilis. |
| | PATIENTS: Forty patients with untreated early syphilis who underwent lumbar puncture. | | | RESULTS: Cerebrospinal fluid cell count was not available for one sample, and this patient was excluded from analysis. | | | MEASUREMENTS: Cerebrospinal fluid cell count, protein, VDRL test, and antibodies to Treponema pallidum by microhemagglutination test for T pallidum (MHA-TP) and fluorescent treponemal antibody absorption test (FTA-ABS); albumin ratio; and IgG index. |
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http://www.aegis.com/aidsline/1995/apr/M9540279.html
(472 words)
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| | New Page 2 |
| | · Syphilis during pregnancy treated with appropriate penicillin, but no decrease in quantitative VDRL after treatment. | | | Labs: VDRL, HIV, CBC, LFTs, UA, CSF (VDRL/total protein/cell count), CXR, long bone films, eye exam, audiology exam. | | | Evaluate all newborns born to mothers with positive nontreponemal test (VDRL, RPR) confirmed by positive treponemal test (FTA) and one or more of the following characteristics: |
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http://www.metrohealth.org/clinical/NICU/BBook/ID2.htm
(1405 words)
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| | Procedure VDRL |
| | A TPPA will also be performed on any serum reactive VDRL or RPR unless the TPPA has been reactive in the past. | | | The following substances can adversely affect the results: | | | A reactive VDRL will have a quantitative titer performed. |
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http://health.ucsd.edu/labref/P858.html
(67 words)
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| | VDRL - definition of VDRL by the Free Online Dictionary, Thesaurus and Encyclopedia. |
| | This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. | | | VDRL is not available in the general English dictionary and thesaurus. | | | You may also use the word browser links: |
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http://www.thefreedictionary.com/VDRL
(101 words)
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| | Allina Medical Labs Collections Manual VDRL-CSF |
| | This site is presented for information only and is not intended to substitute for professional medical advice. | | | Positive VDRL and repeated the next day before reporting. |
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http://www.allina.com/ahs/allinalabs.nsf/ad88a4dd4aa66fe086256a47004f30e8/a6ed363a70a7099f86256b14007395e1?OpenDocument
(39 words)
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