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| | Tyrosinase papers in Science Magazine |
 | | Demonstration of Tyrosinase in Melanocytes of the Human Hair Matrix by Autoradiography. | | | Tyrosinase in Human Skin: Demonstration of Its Presence and of Its Role in Human Melanin Formation. | | | Mammalian Tyrosinase Catalyzes Three Reactions in the Biosynthesis of Melanin. |
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http://www.cwu.edu/%7Everheys/tyrosinaseSciencePapers.htm
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| | BioMed Central Full text Improved immunohistochemical evaluation of micrometastases in sentinel lymph nodes of ... |
| | Tyrosinase alone or any other immunomarker used individually, would be less sensitive than a cocktail. | | | We did not compare tyrosinase alone with the cocktail because the questionable contribution of such a study would not be offset by the additional cost involved. | | | The cocktail was not compared with S-100 in this study, as its role in evaluation of sentinel lymph nodes of melanoma was already demonstrated to be unreliable even in comparison to MART-1 and Melan-A individually in the previous study [6]. |
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http://www.biomedcentral.com/1471-2407/3/15
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| | Modification of ocular defects in mouse developmental glaucoma models by tyrosinase. |
| | Modification of ocular defects in mouse developmental glaucoma models by tyrosinase.These experiments raise the possibility that a tyrosinase/l-dopa pathway modifies human PCG, which could open new therapeutic avenues. | | | Using Cyp1b1-/- mice, we identified the tyrosinase gene (Tyr) as a modifier of the drainage structure phenotype, with Tyr deficiency increasing the magnitude of dysgenesis. | | | The severe dysgenesis in eyes lacking both CYP1B1 and TYR was alleviated by administration of the tyrosinase product dihydroxyphenylalanine (l-dopa). |
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http://www.pdg.cnb.uam.es/UniPub/iHOP/gp/9813257.html
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| | Published Papers |
| | King RA, Olds DP, 1985, Hairbulb tyrosinase activity in oculocutaneous albinism: suggestions for pathway control and block location. | | | 2003, Identification and characterization of a DNase hypersensitive region of the human tyrosinase gene. | | | 1998, Mutations of the human tyrosinase gene associated with tyrosinase related oculocutaneous albinism (OCA1). |
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http://albinism.med.umn.edu/pubs.htm
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| | MedFriendly.com: Tyrosinase inhibitor |
| | Tyrosinase inhibitors are important ingredients of some medications that help to decrease some types of colored spots on people's skin. | | | Tyrosinase increases the rate of oxidation of certain substances in the body. | | | This is because tyrosinase inhibitors work against the oxidation caused by tyrosinase. |
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http://www.medfriendly.com/tyrosinaseinhibitor.html
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| | 78A-31 Tyrosinase Inhibitor from Lemon Peel |
| | Thus, tyrosinase inhibitors become important not only in food to prevent browning but also in cosmetic and medicinal products in relation to hyperpigmentation. | | | OBJECTIVE: The objective of present study is to purify the tyrosinase inhibitor in the lemon peel and to identify the mechanisms of its inhibition. | | | Tyrosinase could cause discoloration of food and reduces the nutritional value. |
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http://ift.confex.com/ift/2000/techprogram/paper_3416.htm
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| | changpub |
| | The effects of hemoperfusion using coated charcoal or tyrosinase artificial cells on middle molecules and tyrosine in brain and serum of hepatic coma rats. | | | NISHIYA T, M. Circular Dichroism Study of Membrane Dynamics Focused on Effect of Monosialoganglioside. | | | Tyrosinase immobilized within artificial cells for detoxification in liver failure. |
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http://www.medicine.mcgill.ca/artcell/changpub.htm
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| | A distal tyrosinase upstream element stimulates gene expression in neural-crest-derived melanocytes of transgenic mice: ... |
| | A distal tyrosinase upstream element stimulates gene expression in neural-crest-derived melanocytes of transgenic mice: position-independent and mosaic expression | | | promoter and human tyrosinase cDNA were introduced into genetically albino | | | A distal tyrosinase upstream element stimulates gene expression in neural-crest-derived melanocytes of transgenic mice: position-independent and mosaic expression -- Porter and Meyer 120 (8): 2103 -- Development |
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http://dev.biologists.org/cgi/content/abstract/120/8/2103
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| | Independent regulation of tyrosinase by the hypopigmenting cytokines TGF beta1 and TNF alpha and the melanogenic ... |
| | Thus, tyrosinase activity and the rate of melanin formation in B16 melanocytes might reflect simply the balance between alpha-MSH stimulation and TGF beta1 or TNF alpha inhibition, acting by independent mechanisms. | | | Since TGF beta1 or TNF alpha block the differentiation programs induced by throphic hormones in other cell types, we studied tyrosinase regulation by alpha-MSH in the presence of the hypopigmenting cytokines, as well as the effects of the cytokines on several aspects of alpha-MSH signaling. | | | The intracellular levels of tyrosinase mRNA, protein and enzymatic activities were also upregulated by alpha-MSH in cells pretreated with TGF beta1 or TNF alpha. |
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http://www.pdg.cnb.uam.es/UniPub/iHOP/gp/2127167.html
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| | Catechol Oxidase (Tyrosinase) - Enzymes |
| | In these two types of animals with this enzyme that denatures at normal body temperatures, the black is formed only on the colder extremities of the body. | | | Other names for catechol oxidase are diphenol oxidase and tyrosinase. | | | What does this have to do with Siamese Cats? |
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http://www.science-projects.com/Tyrosinase.htm
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| | Comparison of Tyrosinase-related Protein-2, S-100, and Melan A Immunoreactivity in Canine Amelanotic Melanomas -- Choi ... |
| | Frost D, Lasota J, Miettinen M: Gastrointestinal stromal tumors and leiomyomas in the dog: a histopathologic, immunohistochemical, and molecular genetic study of 50 cases. | | | Boyle JL, Haupt HM, Stern JB, Multhaup HAB: Tyrosinase expression in malignant melanoma, desmoplastic melanoma, and peripheral nerve tumors. | | | In the present study, we did not detect TRP-2 |
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http://www.vetpathology.org/cgi/content/full/40/6/713
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| | MedlinePlus Medical Encyclopedia: Albinism |
| | This is due to a genetic defect in tyrosinase -- the enzyme responsible for metabolizing tyrosine. | | | Type 2 albinism is due to a defect in the "P" gene. | | | In Type 1 albinism defects in the metabolism of tyrosine lead to failure in converting this amino acid to melanin. |
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http://www.nlm.nih.gov/medlineplus/ency/article/001479.htm
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| | Expression of the Microphthalmia-associated Basic Helix-Loop-Helix Leucine Zipper Transcription Factor Miin Avian ... |
| | [even if the promoter of some genes, like QNR-71 (12) and Tyrosinase | | | Bentley N. J., Eisen T., Goding C. Melanocyte-specific expression of the human tyrosinase promoter: activation by the microphthalmia gene product and role of the initiator. | | | Bertolotto C., Bille K., Ortonne J. P., Ballotti R. Regulation of tyrosinase gene expression by cAMP in B16 melanoma cells involves two CATGTG motifs surrounding the TATA box: implication of the microphthalmia gene product. |
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http://cgd.aacrjournals.org/cgi/content/full/10/7/525
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