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Topic: Trophoblast



  
 Trophoblasts and Cancer
Thus, the greater the incidence of a chorionepitheliomatous exhibition (trophoblast) in the metastases, the greater the degree of malignancy.
Above all else, the trophoblastic or unitarian thesis urges that the alternative non-trophoblastic or non-unitarian thesis, which is at present overwhelmingly the dominant hypothesis, be scrutinized in the light of whatever experimental evidence might exist in its support.
Were pregnancy trophoblast in vivo or in situ to lack the humorally mediated checking influences that are lacking in vitro then such tissue would expectedly behave as it does in vitro and be exhibited in the fiercely malignant fashion of primary uterine chorionepithelioma.
http://cancercure.ws/trophoblast.htm   (9925 words)

  
 Science Paper on the Trophoblast Theory of Cancer - A Layman's Paper
Seeing this change in trophoblast behavior and the onset of activity of the fetal pancreas has more than mere coincidence, Beard began to speculate in his correspondence with physicians about the possibility that the function of both the mother's and the fetus' pancreases were somehow involved in the resolution or destruction of the trophoblast.
In their role, trophoblasts mediate the implantation of the individual, but they are never incorporated into the body of the individual or fetus.
That is something for research to definitely establish, and we need not concern ourselves too much on this point.
http://www.cancure.org/trophoblastic_nature_of_cancer.htm   (1542 words)

  
 Angiopoietin-1 and Angiopoietin-2 Activate Trophoblast Tie-2 to Promote Growth and Migration during Placental ...
C: The effect of Ang-2 on trophoblast migration was assessed in a fashion similar to that of the analysis of Ang-1 in B.
role for angiopoietins as regulators of trophoblast behavior in
role for angiopoietins as regulators of trophoblast behavior
http://ajp.amjpathol.org/cgi/content/full/156/6/2185   (6641 words)

  
 Trophoblast differentiation and invasion: a lesson to be gained for understanding implantation of the human embryo
To our knowledge c-jun has not been studied in the human trophoblast.
Antigenic heterogeneity of human cytotrophoblast and evidence for the transient expression of MHC class I antigens distinct from HLA-G. Placenta 14, 571-582, 1993
a5ß1 to fibronectin, a6ß1 to laminin etc. In the particular case of trophoblast, several studies (9, 17, 18, 19), including our own (20,21), have shown that vCTB and evCTB express different integrins.
http://www.gfmer.ch/Endo/Lectures_08/trophoblast_differentiation.htm   (7510 words)

  
 Phagocytosis as a potential mechanism for microbial defense of mouse placental trophoblast cells -- Amarante-Paffaro et ...
Under in vitro conditions, erythrophagocytosis by rodent trophoblast
Welsh AO and Enders AC 1987 Trophoblast–decidual cell interaction and establishment of maternal blood circulation in the parietal yolk sac placenta of the rat.
Enders AC and Schlafke S 1969 Cytological aspects of trophoblast uterine interactions in early implantation.
http://www.reproduction-online.org/cgi/content/full/128/2/207   (4796 words)

  
 The role of trophoblast in the physiological change in decidual spiral arteries -- Kam et al. 14 (8): 2131 -- Human ...
of the uterine mucosa but no trophoblast is present.
(1983) Uteroplacental arterial changes related interstitial trophoblast migration in early human pregnancy.
the deeper portions of such arteries had no trophoblast in the
http://humrep.oxfordjournals.org/cgi/content/full/14/8/2131   (3237 words)

  
 Small Guanosine Triphospatase RhoA and Rho-Associated Kinase as Regulators of Trophoblast Migration -- Shiokawa et al. ...
the ECM encountered by the trophoblast in the extravillous pathway
of the factors that determine behavior of the trophoblast in
that the RhoA-ROCK pathway in trophoblast cells is involved
http://jcem.endojournals.org/cgi/content/full/87/12/5808   (4401 words)

  
 Hepatocyte Growth Factor Stimulates Trophoblast Invasion: A Potential Mechanism for Abnormal Placentation in ...
of trophoblast proliferation in response to HGF has suggested
Western blot analysis for Met expression in ED
These studies suggest that HGF has an important role in placental
http://jcem.endojournals.org/cgi/content/full/84/11/4092   (3532 words)

  
 Science Paper on the Trophoblast Theory of Cancer - A Technical Paper
The unifying basis of trophoblast as cancer by means of Beard's insights was rediscovered later by these experimental approaches, but Beard's approach represents the first rational treatment for cancer.
In the 1940s Howard Beard [b] and others developed more sensitive techniques similar to those used for detecting pregnancy, focusing on hCG, which they found in all cancer sera [c] to varying degrees.
As it is the thesis that cancer it trophoblastic, it is meaningless or a tautology to say "the cancer of cancer" as is implied in the terms chorio-carcinoma, or trophoblastic carcinoma.
http://www.cancure.org/science_paper1.htm   (5925 words)

  
 The HAND1 Basic Helix-Loop-Helix Transcription Factor Regulates Trophoblast Differentiation via Multiple Mechanisms -- ...
Primary culture experiments have suggested that at least three functionally distinct trophoblast subpopulations exist in the
HES-2 and -3 are expressed in all trophoblast
These studies therefore defined a subpopulation of trophoblast
http://mcb.asm.org/cgi/content/full/20/2/530   (6663 words)

  
 Trophoblast differentiation in vitro: establishment and characterisation of a serum-free culture model for murine ...
Faria TN, Deb S, Kwok SCM, Talamantes F and Soares MJ 1990 Ontogeny of placental lactogen-I and placental lactogen-II expression in the developing rat placenta.
Trophoblasts growing on an extracellular matrix (ECM) substrate
In this study, we have developed a serum-free model for secondary
http://www.reproduction-online.org/cgi/content/full/128/1/53   (7809 words)

  
 SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant cell differentiation -- Takahashi et al. ...
SOCS3 is expressed in trophoblast in the placenta
of SOCS3-deficient trophoblasts and responsible for the embryonic
SOCS3 was expressed in the heart, spleen, lung and liver.
http://embojournal.npgjournals.com/cgi/content/full/22/3/372   (5895 words)

  
 Ectopic Transplantation of Equine Invasive Trophoblast -- Adams and Antczak 64 (3): 753 -- Biology of Reproduction
Immunological aspects of the equine endometrial cup reaction.
expressed by equine trophoblast [42] and, in the few cases studied,
The maternal leukocyte response to the endometrial cups in horses is correlated with the developmental stages of the invasive trophoblast cells.
http://www.biolreprod.org/cgi/content/full/64/3/753   (5107 words)

  
 Inhibition of trophoblast stem cell potential in chorionic ectoderm coincides with occlusion of the ectoplacental ...
Reliance on in situ hybridisation patterns of diploid trophoblast
for FGF4 signalling in diploid trophoblast, is uniformly expressed
Rossant, J. and Tamura-Lis, W. Effect of culture conditions on diploid to giant-cell transformation in postimplantation mouse trophoblast.
http://dev.biologists.org/cgi/content/full/129/16/3913   (6677 words)

  
 Transcriptional Activation of the Decidual/Trophoblast Prolactin-Related Protein Gene -- Orwig and Soares 140 (9): 4032 ...
However, Ets 2 does not appear to interact
Deletion analysis of the d/tPRP promoter in decidual and trophoblast cells.
Apart from its biological relevance, d/tPRP expression is associated with
http://endo.endojournals.org/cgi/content/full/140/9/4032   (4898 words)

  
 Trophoblast - Wikipedia, the free encyclopedia
Failure of the trophoblast to invade sufficeintly may be important in the development of some cases of pre-eclampsia.
The invasion of a specific type of trophoblast (extravillous trophoblast) into the maternal uterus is a vital stage in the establishment of pregnancy.
This page was last modified 23:09, 23 December 2005.
http://en.wikipedia.org/wiki/Trophoblast   (107 words)

  
 Cell-mediated infection of human placental trophoblast with HIV in vitro.
Cell-mediated infection of human placental trophoblast with HIV in vitro.
In order to investigate how human immunodeficiency virus (HIV) gains entry to the placenta, we have performed in vitro experiments in which highly purified trophoblast cells isolated from term human placentas were examined for their susceptibility to HIV infection.
The state of the art may have changed since the publication date.
http://www.aegis.com/aidsline/1992/mar/M9230501.html   (502 words)

  
 Altered phenotype of HLA-G expressing trophoblast and decidual natural killer cells in pathological pregnancies -- ...
However, this will be difficult, as trophoblast function
We observed that HLA-G was expressed on all extravillous trophoblast
The expression of HLA-G in ectopic trophoblastic tissue as described
http://humrep.oxfordjournals.org/cgi/content/full/17/4/1072   (4666 words)

  
 USF1 and USF2 Mediate Inhibition of Human Trophoblast Differentiation and CYP19 Gene Expression by Mash-2 and Hypoxia ...
of cultured human trophoblast cells, and CYP19 promoter activity.
In the present study, we observed that unexpectedly
levels of Mash-2 were maintained when trophoblasts were cultured
http://mcb.asm.org/cgi/content/abstract/23/17/6117   (594 words)

  
 Trophoblast
Histologic Classification of Gestational Trophoblastic Lesions (World Health Organization Classification of Gestational Trophoblastic Lesions).
Immunohistochemical localization of placental lactogen and chorionic gonadotropin in the normal placenta and trophoblastic tumors with emphasis on intermediate trophoblast and the placental-site trophoblastic tumor.
The TNM staging system of the American Joint Committee on Cancer (AJCC) and the International Union Against Cancer (UICC)(2) and the corresponding staging system of the International Federation of Gynecology and Obstetrics (FIGO) are recommended and shown below.
http://dpalm.med.uth.tmc.edu/cancerprotocols/trop.htm   (1735 words)

  
 trophoblast - OneLook Dictionary Search
trophoblast : The On-line Medical Dictionary [home, info]
trophoblast : Dorland's Illustrated Medical Dictionary [home, info]
We found 13 dictionaries with English definitions that include the word trophoblast:
http://www.onelook.com/?w=trophoblast   (186 words)

  
 Trophoblast Research (Trophoblast Research, Vol 4) New, Used Books, Cheap Prices, ISBN 0306435209
Search: Trophoblast Research (Trophoblast Research, Vol 4) : ISBN: 0306435209
Trophoblast Research (Trophoblast Research, Vol 4) New, Used Books, Cheap Prices, ISBN 0306435209
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http://www.bookfinder4u.com/detail/0306435209.html   (180 words)

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