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| | Diabetes Monitor - troglitazone (Rezulin) |
 | | Talk Papers are subject to change as more information becomes available. | | | ALT levels should be measured at the start of Rezulin therapy and monthly for eight months, then every two months for the remainder of the first year of therapy and periodically thereafter. | | | Patients taking REZULIN should consult with their physicians as soon as possible to discuss alternative therapies. |
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http://www.diabetesmonitor.com/rezulin.htm
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| | MedlinePlus Drug Information: Troglitazone (Systemic) |
| | Children— Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of troglitazone in children with use in other age groups. | | | Other medicines—Do not take other medicines during the time you are taking troglitazone unless they have been discussed with your doctor. | | | When you are taking troglitazone, it is especially important that your health care professional know if you are taking any of the following: |
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http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/203433.html
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| | troglitazone (oral) - [Medication] |
| | Your pharmacist has additional information about troglitazone written for health professionals that you may read. | | | Do not take any over-the-counter cough, cold, allergy, pain, or weight-loss medications without first talking to your doctor. | | | Before taking this medication, tell your doctor if you |
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http://www.peacehealth.org/kbase/multum/d04122a1.htm
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| | Troglitazone Inhibits Vascular Smooth Muscle Cell Growth and Intimal Hyperplasia -- Law et al. 98 (8): 1897 -- Journal ... |
| | Quantitative image analysis revealed that troglitazone-treated rats had 62% ( P < 0.001) less neointima/media area ratio 14 d after balloon injury of the aorta compared with injured rats that received no troglitazone. | | | Troglitazone Improves Psoriasis and Normalizes Models of Proliferative Skin Disease: Ligands for Peroxisome Proliferator-Activated Receptor-{gamma} Inhibit Keratinocyte Proliferation | | | This effect was associated with an inhibition (by 73±4%, P < 0.01) by troglitazone of the transactivation of the serum response element, which regulates c-fos expression. |
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http://www.jci.org/cgi/content/abstract/98/8/1897
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| | Rezulin Online, Description, Chemistry, Ingredients - Troglitazone (removed from the US market 3/21/00) - RxList ... |
| | It is recommended that serum transaminase levels be checked at the start of therapy, monthly for the first six months of therapy, every two months for the remainder of the first year of troglitazone therapy, and periodically thereafter. | | | An additional Rezulin-treated patient had a liver biospy which was also consistent with an idiosyncratic drug reaction. | | | Liver function tests also should be obtained for patients at the first symptoms suggestive of hepatic dysfunction, e.g., nausea, vomiting, abdominal pain, fatigue. |
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http://www.rxlist.com/cgi/generic/troglitazone.htm
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| | Ortho Tri-Cyclen store - Buy Ortho Tri-Cyclen online |
| | Additional monitoring of your dose or condition may be needed if you are taking barbiturates, carvedilol, corticosteroids, felbamate, griseofulvin, HIV protease inhibitors, modafinil, metoprolol, pioglitazone, penicillin or tetracycline antibiotics, theophylline, topiramate, troglitazone, troleandomycin, or medicine for seizures. | | | Do not take this medicine if you are also taking nevirapine or rifampin. |
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http://ortho-tri-cyclen.medical-dictionary-search-engines.com/
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| | Medical Breakthroughs - Learn More About Heart Disease |
| | Thiazolidinediones, which control glucose levels by making muscles more sensitive to insulin and reduce the amount of glucose that the liver produces. | | | Both agents, acting primarily by different mechanisms of action, also have demonstrated potential beneficial effects on serum lipid profiles. | | | Clinical trials suggest that oral antidiabetic agents - particularly the new noninsulin secretagogues (including Troglitazone and Metformin, which act on the liver and skeletal muscle) - may be useful in delaying or preventing development of Type II diabetes. |
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http://www.healthscout.com/template.asp?page=ency&ap=1&encyid=150
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| | Troglitazone - Wikipedia, the free encyclopedia |
| | It was introduced in the late 1990s but turned out to be associated with an idiosyncratic reaction leading to drug-induced hepatitis. | | | Troglitazone is a ligand to both PPAR&- more strongly - PPAR&;. | | | Troglitazone also contains an α-tocopheroyl moiety, potentially giving it vitamin E -like activity in addition to its PPAR activation. |
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http://encyclozine.com/Rezulin
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| | Encyclopedia4U - Insulin - Encyclopedia Article |
| | insulin resistance reducers (eg, one of a new class of drugs (troglitazone Rezulin was the first) which increase cellular sensitivity to insulin) | | | There is a special channel in the cell membrane through which glucose from the blood can enter the cell. |
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http://www.encyclopedia4u.com/i/insulin.html
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| | REZULIN TO BE WITHDRAWN FROM THE MARKET |
| | FDA today asked the manufacturer of Rezulin (troglitazone) -- a drug used to treat type 2 diabetes mellitus-- to remove the product from the market. | | | P00-8 FOOD AND DRUG ADMINISTRATION FOR IMMEDIATE RELEASE Print Media: 301-827-6242 March 21, 2000 Consumer Inquiries:888-INFO-FDA |
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http://www.fda.gov/bbs/topics/NEWS/NEW00721.html
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| | Ann Intern Med -- Sign In Page |
| | Metabolic Effects of Troglitazone Monotherapy in Type 2 Diabetes Mellitus: A Randomized,... | | | To view this item, select one of the options below: | | | Please note: PDFs are free 6 months after publication. |
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http://www.annals.org/cgi/content/full/128/3/176
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| | Pharmacology |
| | Drugs found to have serious side effects and subsequently withdrawn from the market | | | Thalidomide ( 1950s – 1960s), diethylstilbestrol ( 1970s), phenformin and buformin, Fen-phen, phentermine, dexfenfluramine & fenfluramine ( 1997), troglitazone ( 2000), cerivastatin ( 2001), rapacuronium (ORG 9487) |
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http://www.sciencedaily.com/encyclopedia/pharmacology
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