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| | Topiramate reduces frequency of migraines |
 | | "Topiramate, 100 or 200 milligrams per day, was effective as a preventive therapy for patients with migraine," the researchers conclude. | | | CHICAGO — Topiramate, a drug used to treat epilepsy, is effective for preventing migraine headaches, according to an article in the April issue of The Archives of Neurology, one of the JAMA/Archives journals. | | | "Based on its efficacy herein and the tolerability profile established from its use in patients with epilepsy, topiramate should be considered a first-line treatment option for the prevention of migraine headaches," they write. |
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http://www.eurekalert.org/pub_releases/2004-04/jaaj-trf041504.php
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| | Topiramate - Drugs & Vitamins - Drug Library - DrugDigest |
| | Topiramate may also be prescribed for other conditions, such as prevention of migraine headaches. | | | Topiramate should be taken on a daily basis as prescribed by your health care professional for the prevention of migraine headaches. | | | Contact your pediatrician or health care professional regarding the use of this medicine in children. |
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http://www.drugdigest.org/DD/DVH/SideEffects/0,3917,670Topiramate,00.html
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| | Evaluation of open-label topiramate for scar therapy |
| | To determine whether topiramate is effective in scar therapy, we conducted an investigational pilot study in subjects with raised or discolored scars that were at least 2 years old to minimize any natural occurring improvement. | | | The results of this investigational pilot study, conducted in ten patients with scars that were raised or discolored, and at least 2 years old, suggest that the antiepileptic medication topiramate may be a novel and effective treatment for scar therapy. | | | Additionally, seven of the ten subjects described that before topiramate they had failed various surgical or topical forms of scar therapy, and no subject described using any other treatments for scar therapy during the trial. |
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http://dermatology.cdlib.org/95/original/scars/shapira.html
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| | Topiramate (Topamax), Mood Disorders and PTSD. |
| | Topiramate versus bupropion SR when added to mood stabilizer therapy for the depressive phase of bipolar disorder: a preliminary single-blind study. | | | Augmenting antipsychotic treatment with lamotrigine or topiramate in patients with treatment-resistant schizophrenia: A naturalistic case-series outcome study. | | | Why should physicians prescribe, and patients take, topiramate, when there are mood regulating medications that have been available for many years and which have been shown to be effective in double-blind placebo- controlled studies? |
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http://www.psycom.net/depression.central.topiramate.html
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| | topiramate Drug Information |
| | Topiramate may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, pain relievers, sedative (sleep aids), anxiety medicines, and muscle relaxants. | | | Topiramate is also used to prevent migraine headaches. | | | Seek immediate medical attention if you experience blurred vision, changes in vision, or pain in or around the eyes during treatment with topiramate. |
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http://www.drugs.com/MTM/topiramate.html
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| | Topiramate - Formulary |
| | The change in the mean 4-week migraine headache frequency from baseline to the double-blind phase was -1.4, -2.1, and -2.4 in the topiramate 50, 100, and 200 mg/d groups, respectively, versus -1.1 in the placebo group. | | | The change in the mean 4-week migraine headache frequency from baseline to the double-blind phase was -1.3, -2.1, and -2.2 in the topiramate 50, 100, and 200 mg/d groups, respectively, versus -0.8 in the placebo group. | | | Topiramate therapy has been associated with hyperchloremic, non-anion gap metabolic acidosis. |
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http://www.actmagazine.com/formulary/article/articleDetail.jsp?id=128763
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| | Topiramate news articles |
| | Some anti-seizure drugs (such as gabapentin and topiramate) that are used to treat epilepsy also seem to prevent migraine headaches. | | | These measures are not always successful but recently a new therapy, Topamax (topiramate) has been licensed for prophylactic use in patients who have more than... | | | Muscle relaxants and seizure medicines such as gabapentin and topiramate are also employed. |
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http://www.mongabay.com/drugs/drugs/Topiramate.html
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| | American Family Physician: Topiramate treatment in alcohol-dependent patients |
| | The study was a double-blind, randomized, controlled clinical trial comparing topiramate with placebo in alcohol-dependent patients. | | | The authors conclude that topiramate as an adjuvant to a medication-compliance program was superior to placebo in improving drinking outcomes. | | | Oral topiramate reduces the consequences of drinking and improves quality of life of alcohol-dependent individuals. |
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http://www.findarticles.com/p/articles/mi_m3225/is_3_72/ai_n14888507
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| | MedlinePlus Drug Information: Topiramate (Systemic) |
| | Topiramate is also used to help prevent migraine headaches in adults. | | | Mothers who are taking this medicine and who wish to breast-feed should discuss this with their doctor. | | | In deciding to use a medicine, the risks of taking topiramate must be weighed against the good it will do. |
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http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/203085.html
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| | Topiramate: a potential new medication for treating alcoholism |
| | Therefore, topiramate can serve to deliver treatment when it is needed most - at the point of crisis when the patient is still drinking and looking for help to quit. | | | A third medication called acamprosate (calcium acetyl homotaurinate), used in Europe and elsewhere to prevent relapse in alcoholics, is currently under review for use by the U.S. Food and Drug Administration. | | | Johnson conducted a "proof-of-concept" clinical trial, an experiment designed to test the direct consequences of an idea. |
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http://www.eurekalert.org/pub_releases/2004-08/ace-tap080504.php
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| | MedlinePlus Drug Information: Topiramate |
| | Talk to your doctor about the risks of using this medication for your condition. | | | Avoid exposure to heat, drink plenty of fluids and tell your doctor if you have a fever, headache, muscle cramps, an upset stomach, or are not sweating as usual. | | | This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. |
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http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a697012.html
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| | Ivanhoe's Medical Breakthroughs - Treating Alcoholism With Drugs |
| | Results showed patients taking topiramate were twice as likely to experience improved well-being than those on placebo. | | | Both before and after drug treatment, researchers measured three elements of psychological and social well-being: severity of alcohol dependence, reported quality of life, and consequences of drinking. | | | The were also 2.5-times more likely to report abstinence from alcohol, twice as likely to report overall satisfaction with life, and reported fewer instances of harmful drinking consequences. |
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http://www.ivanhoe.com/channels/p_channelstory.cfm?storyid=9480
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| | Topiramate (Topamax) |
| | Potential interactions between topiramate and standard AEDs were assessed in controlled clinical pharmacokinetic studies in patients with epilepsy. | | | Therefore, patients receiving risperidone in combination with topiramate should be closely monitored for clinical response. | | | Safety and effectiveness in pediatric patients have not been established for the prophylaxis treatment of migraine headache. |
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http://www.healthyplace.com/communities/bipolar/treatment/medications/topamax.asp
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| | News - Topiramate Used for Successful Treatment of Diabetic Peripheral Neuropathy: a Case Report |
| | Topiramate is an anticonvulsant that is gaining acknowledgment in the treatment of neuropathic pain syndromes, but few data have been published on the use of this drug for diabetic peripheral neuropathy. | | | According to Dr. Kline, the patient has tolerated the topiramate well, her physical examination has remained stable, and her neuropathy has not progressed. | | | "Topiramate may be effective in the treatment of diabetic peripheral neuropathies, but randomised controlled trials will be needed," the researchers conclude. |
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http://www.docguide.com/news/content.nsf/news/8525697700573E1885256D9000311902
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| | topiramate in bipolar disorder |
| | These data could support a major shift in strategy, away from valproate as a mainstay mood stabilizer, because of the associated weight problems (2.5 kilogram gain in this 6-week study), as they so often are seen in practice); toward a medication whose effectiveness is in serious question but which does not have the weight-gain problem. | | | This re-opens the case for consideration of topiramate as a mood stabilizer, in my opinion, but we'll need more data now: this study only re-opens the question of effectiveness. | | | Update 12/2005: at this point there are two randomized trials in which topiramate did not outperform placebo as an add-on mood stabilizer in bipolar disorder. |
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http://www.psycheducation.org/depression/meds/topiramate.htm
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| | Topiramate Shows Promise in Treating Alcoholism JoinTogether.org |
| | Alcohol consumption facilitates dopamine neurotransmission; topiramate decreases dopamine release through antagonism of glutamate activity and facilitation of the inhibitory neurotransmitter GABA. | | | The clinical trial's findings are published in the August 2004 issue of Alcoholism: Clinical & Experimental Research. | | | A clinical trial for the new drug topiramate is showing promising results in reducing consumption and craving among alcohol-dependent patients who are not yet abstinent, Medical News Today reported Aug. 16. |
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http://www.jointogether.org/sa/news/summaries/reader/0,1854,574216,00.html
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| | Topiramate prevents migraines |
| | Among 468 patients—87% of them women—the antiepileptic drug topiramate (Topamax—Ortho McNeil) was effective in preventing migraine attacks and reducing the use of rescue medications, according to a study in today’s JAMA. | | | Jan Lewis Brandes, MD, from the Nashville Neuroscience Group, Nashville, Tenn., and colleagues conducted the study at 52 North American outpatient clinical centers. | | | Benefits were evident during the first month of therapy in those treated with daily topiramate doses of 100 or 200 mg. |
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http://www.pharmacist.com/articles/h_ts_0482.cfm
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| | Encyclopedia topic: Topiramate |
| | Patients who take topiramate and who feel pain in or around their eyes, or notice a loss of vision, visual acuity, or blurred vision, are advised to seek consultation with their physician as soon as reasonably possibly. | | | The Food and Drug Administration (FDA) has issued a notification alerting physicians who prescribe topiramate, and their patients, to the risk of vision loss (blindness). | | | However, that use is not actively promoted by the drug's manufacturer and is an "off-label" use. |
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http://www.absoluteastronomy.com/encyclopedia/t/to/topiramate.htm
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| | Epilepsy Medications: topiramate |
| | Other drugs can affect and be affected by Topiramate. | | | Topiramate is used as adjunctive therapy in adults with complex partial seizure disorder. | | | You need to be aware that any changes in your anticonvulsant therapy, there may be an increase in seizure frequency. |
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http://www.neuro.jhmi.edu/Epilepsy/meds/topamax.html
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| | topiramate - Migraine Headaches and other Neurological Disorders treatment, symptoms and medications |
| | Symptoms have typically occurred within the first month of therapy, with patients reporting an acute onset of decreased vision and/or eye pain. | | | topiramate - Migraine Headaches and other Neurological Disorders treatment, symptoms and medications | | | If patients develop this syndrome, the treatment is to discontinue topiramate as rapidly as possible, according to the judgment of the treating physician. |
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http://www.medicinenet.com/topiramate/article.htm
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| | AAN: Low-Dose Topiramate Does Not Interact with Oral Contraceptives |
| | In fact, the absence of a clinically significant effect of topiramate on NE and EE pharmacokinetics is supported by the observation that 90 percent confidence intervals for Cmax and AUC were within bioequivalence limits. | | | Topiramate's treatment effect was not significant for Cmax or AUC in any treatment group. | | | Topiramate is a broad-spectrum anti-epileptic drug with a clinical profile that may favor its use in women, including effectiveness in disorders that are more common in women (for example, juvenile myoclonic epilepsy and migraine) and low risk of weight gain. |
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http://www.pslgroup.com/dg/22f8ca.htm
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| | Topiramate - buy Topiramate online - order Topiramate without prescription |
| | If you're looking for a better way to order Topiramate or other medicine, AllNetMeds.com is right for you! | | | Answer- You can obtain quality prescription medications at a great savings through our affiliated partners, leaders in discount drugs online. | | | Topiramate - Used with other drugs to control various types of convulsions and seizures of epilepsy. |
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http://www.allnetmeds.com/o/n_dr/Topiramate.shtml
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| | Topiramate-Induced Psychosis -- KOBER and GABBARD 162 (8): 1542 -- American Journal of Psychiatry |
| | Hedges DW, Reimherr FW, Hoopes SP, Rosenthal NR, Kamin M, Karim R, Capece JA: Treatment of bulimia nervosa with topiramate in a randomized, double-blind, placebo-controlled trial, part 2: improvement in psychiatric measures. | | | Andrade C: Confusion and dysphoria with low-dose topiramate in a patient with bipolar disorder. | | | Lykouras L, Hatzimanolis J: Adjunctive topiramate in the maintenance of treatment of bipolar disorders: an open-label study. |
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http://ajp.psychiatryonline.org/cgi/content/full/162/8/1542
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| | Arch Neurol -- Abstract: Topiramate in Migraine Prevention: Results of a Large Controlled Trial, April 2004, ... |
| | Conclusion Topiramate, 100 or 200 mg/d, was effective | | | Stephen D. Silberstein, MD Walter Neto, MD Jennifer Schmitt, MS David Jacobs, MD ; for the MIGR-001 Study Group | | | Arch Neurol -- Abstract: Topiramate in Migraine Prevention: Results of a Large Controlled Trial, April 2004, Silberstein et al. |
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http://archneur.ama-assn.org/cgi/content/abstract/61/4/490
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| | Focus on Topiramate - a new anti-epileptic |
| | Topiramate may also cause agitation and emotional lability (which may manifest as abnormal behaviour) and depression. | | | Topiramate is a sulphamate-substituted monosaccharide with a structure distinct from other AEDS. | | | Faught et al (1996) conducted a randomized double-blind comparison of three doses of topiramate (200, 400, and 600 mg/day) and placebo as adjunctive therapy in patients with refractory partial onset epilepsy receiving one or two other anti-epileptics at therapeutic concentrations. |
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http://www.priory.com/focus7.htm
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| | Topiramate : Epilepsy.com/Professionals |
| | Co-Existing Disorders > Renal Disorders > Effects on specific AEDs > Topiramate | | | 70 These figures suggest that the elimination half-life of topiramate is 36 hours in patients with severe renal insufficiency. | | | The clearance of topiramate is decreased by 42% in patients with moderate renal impairment (creatinine clearance 30—69 mL/min/1.73m2) and by 54% in subjects with severe impairment (creatinine clearance less than 30mL/min/1.73m2). |
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http://professionals.epilepsy.com/page/aed_topiramate.html
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| | TOPIRAMATE |
| | Topiramate is a sulfamated monose that interferes with calcium and sodium channels; used as an anticonvulsant in the treatment of some seizures including jerking of limbs, frothing at the mouth, and loss of consciousness due to a lesion in a specific cerebral cortex. |
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http://www.chemicalland21.com/arokorhi/lifescience/phar/TOPIRAMATE.htm
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| | News - Binge Eating Disorder Associated with Obesity Can be Treated with Topiramate |
| | People with binge eating disorders associated with obesity can be treated effectively with the anti-epileptic agent topiramate, say researchers in the United States. | | | Three of those given topiramate discontinued due to headache and two because of paresthesias. | | | A DGReview of :"Topiramate in the treatment of binge eating disorder associated with obesity: a randomized, placebo-controlled trial." |
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http://www.docguide.com/news/content.nsf/news/8525697700573E1885256CC4000B66F2
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| | Topiramate for epilepsy |
| | Recently, topiramate has been linked in some people to a potentially life-threatening condition called metabolic acidosis. | | | Topiramate is very effective in reducing partial seizures in most people who take it. | | | While, topiramate is tolerated well by most people and has few serious side effects, a small number of people taking the drug may develop kidney stones. |
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http://www.webmd.com/hw/epilepsy/hw110595.asp
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| | Topiramate or Topamax and Migraine Headache, Epilepsy and Weight Loss |
| | Topiramate or Topamax and Migraine Headache, Epilepsy and Weight Loss | | | Topamax (topiramate) is one of the newly approved anti-epileptic drugs (AED) approved by the FDA in the last 10 years. | | | It is considered a broad spectrum AED because it works to prevent both partial onset and generalized seizures. |
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http://www.loftusmd.com/Articles/AED/topiramate.html
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| | Topomax( Topiramate ) |
| | Patients with hepatic function impairment may have increased Topiramate plasma concentrations and a dosage adjustments may be needed. | | | Use extra caution if you have any liver or kidney impairment. | | | If Stop Taking: Do not stop without consulting your physician and never abruptly are you may develop withdrawal seizures. |
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http://www.psyweb.com/Drughtm/topomax.html
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| | Encyclopedia article on Topiramate [EncycloZine] |
| | Visit Curious-Minds.co.UK for educational games and toys, and science kits. | | | Products related to Topiramate: books, DVD, electronics, garden, kitchen, magazines, music, photo, posters, software, tools, toys, VHS, videogames |
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http://encyclozine.com/Topiramate
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