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Topic: Tobramycin



  
 TOBRAMYCIN
Tobramycin solution for nebulisation is licensed specifically for the management of CF patients aged 6 years and over who are colonised with P.
In line with current clinical practice, baseline renal function should be assessed before commencing tobramycin treatment.
Values approached week 0 values during the 28 day periods when no drug was administered.
http://www.keele.ac.uk/depts/mm/MTRAC/ProductInfo/summaries/T/TOBRAMYCINs.html

  
 Data Sheet
The decision to continue therapy with tobramycin sulfate should be based on the results of susceptibility studies, the severity of the infection, and the important additional concepts discussed in the 'Warnings' section.
If susceptibility tests show that the causative organisms are resistant to tobramycin, other appropriate therapy should be instituted.
In some other clinical studies, no significant difference in the incidence of nephrotoxicity between tobramycin and gentamicin was found.
http://www.medsafe.govt.nz/Profs/datasheet/n/nebcininj.htm

  
 Tobramycin Sulfate
Whether tobramycin is less nephrotoxic than either gentamicin or amikacin when used clinically is controversial.
See also the information in the Drug Interaction and Drug/Lab Interaction sec­tions.
Total irreversible deafness has been reported in some human babies whose mothers re­ceived tobramycin during pregnancy.
http://www.elephantcare.org/Drugs/tobram.htm

  
 tobramycin (inhalation) - [Medication]
If you are using several respiratory medications, the recommended order is bronchodilator first, followed by chest physiotherapy, then other inhaled medications, followed by tobramycin.
Your pharmacist has additional information about tobramycin written for health professionals that you may read.
This does not indicate any change in quality of the medication.
http://www.peacehealth.org/kbase/multum/d00069n1.htm

  
 Pharmacokinetics and Bioavailability of Aerosolized Tobramycin in Cystic Fibrosis* -- Geller et al. 122 (1): 219 -- ...
tobramycin in CF patients has been studied extensively, and
Ramsey, BW, Quan, JM, Otto, KL, et al (1998) Interim analysis of data from an open-label follow-on trial of inhaled tobramycin (PC-TNDS-004) in patients with cystic fibrosis [abstract].
Coates, AL, MacNeish, CF, Lands, LC, et al (1998) A comparison of the availability of tobramycin for inhalation from vented vs unvented nebulizers.
http://www.chestjournal.org/cgi/content/full/122/1/219

  
 critical care forum Full text Endotoxin neutralization and anti-inflammatory effects of tobramycin and ceftazidime in ...
These findings led to the hypothesis that the anti-inflammatory effects might affect the cytokine response during the last phase in our porcine model.
The mechanisms, physiological consequences and potential clinical relevance of this finding need further investigation.
If this effect occurred in vivo, then it would influence the cytokine values during the last part of the experiment.
http://ccforum.com/content/8/1/R35

  
 People Living With Cancer - Drug Database - Description
Tell your health care professional if you are using any other prescription or nonprescription (over-the-counter [OTC]) medicine that is to be used in the eye.
Either the drops or the ointment form of this medicine may be used alone during the day.
In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do.
http://www.oncology.com/plwc/MainConstructor/1,1744,_12-001120-00_17-001029-00_21-008-00_29-00t-00_41-003768,00.asp

  
 Activities of Tobramycin and Six Other Antibiotics against Pseudomonas aeruginosa Isolates from Patients with Cystic ...
These studies indicate little change in susceptibility to tobramycin, despite its extensive use in CF patients.
Our data suggest its continued value in the treatment
patients with CF that we examined were resistant to tobramycin.
http://aac.asm.org/cgi/content/full/43/12/2877

  
 Inhalation of a Dry Powder Tobramycin PulmoSphere Formulation in Healthy Volunteers -- Newhouse et al. 124 (1): 360 -- ...
after 600 mg of nebulized tobramycin in patients with CF, describing
This work was fully funded by Inhale Therapeutic Systems Inc.,
with a clinically available nebulized tobramycin product (TOBI;
http://www.chestjournal.org/cgi/content/full/124/1/360

  
 Technical Report: Precautions Regarding the Use of Aerosolized Antibiotics -- Prober et al. 106 (6): 89 -- Pediatrics
Coates AL, MacNeish CF, Meisner D, The choice of jet nebulizer, nebulizing flow, and addition of albuterol affects the output of tobramycin aerosols.
Steinkamp G, Trummler B, Gappa M, Long-term tobramycin aerosol therapy in cystic fibrosis.
TOBI, tobramycin solution for inhalation; CF, cystic fibrosis; FEV
http://www.pediatrics.org/cgi/content/full/106/6/e89

  
 Pharmacokinetics and Efficacies of Liposomal and Conventional Formulations of Tobramycin after Intratracheal ...
As a consequence, the level of exposure to tobramycin in the
cepacia in lungs following treatment with liposomal or conventional tobramycin formulations in male Sprague-Dawley rats
of gentamicin, amikacin, or tobramycin markedly changes when
http://aac.asm.org/cgi/content/full/46/12/3776

  
 NEJM -- Intermittent Administration of Inhaled Tobramycin in Patients with Cystic Fibrosis
Fiel, S. Early Aggressive Intervention in Cystic Fibrosis: Is It Time To Redefine Our "Best Practice" Strategies?.
The patients in the tobramycin group were 26 percent (95 percent
inhaled tobramycin in patients with cystic fibrosis and Pseudomonas
http://content.nejm.org/cgi/content/short/340/1/23

  
 Once-daily tobramycin in the treatment of adult patients with cystic fibrosis -- Whitehead et al. 19 (2): 303 -- ...
Intensive treatment of a pseudomonas chest infection in cystic fibrosis: a comparison of tobramycin and ticarcillin, and netilmycin.
CF centres have introduced its use into routine practice for
The pharmacokinetics and toxicity of once-daily tobramycin therapy in children with cystic fibrosis.
http://erj.ersjournals.com/cgi/content/full/19/2/303

  
 TobraDex Prescription Information
Fetal growth retardation and increased mortality rates have been observed in rats with chronic dexamethasone therapy.
There are no adequate and well controlled studies in pregnant women.
These reactions occur in less than 4% of patients.
http://www.alconlabs.com/us/aj/products/RxTher/A23_TobraDexInfo.jhtml

  
 Prevention of Descending Pneumonia in Rats with Perflubron-delivered Tobramycin -- Dickson et al. 10 (10): 1019 -- ...
Prevention of Descending Pneumonia in Rats with Perflubron-delivered Tobramycin -- Dickson et al.
Prevention of Descending Pneumonia in Rats with Perflubron-delivered Tobramycin
All interventions were given 24 hours before a bacterial challenge
http://www.aemj.org/cgi/content/abstract/10/10/1019

  
 Ciprofloxacin plus Piperacillin Compared with Tobramycin plus Piperacillin as Empirical Therapy in Febrile Neutropenic ...
Ciprofloxacin plus Piperacillin Compared with Tobramycin plus Piperacillin as Empirical Therapy in Febrile Neutropenic Patients: A Randomized, Double-Blind Trial -- Peacock et al.
Ciprofloxacin plus Piperacillin Compared with Tobramycin plus Piperacillin as Empirical Therapy in Febrile Neutropenic Patients
and tobramycin plus piperacillin were equally effective empirical
http://www.annals.org/cgi/content/abstract/137/2/77

  
 HealthCentral - General Encyclopedia - tobramycin - ophthalmic
You should promptly seek professional medical care if you have any concern about your health, and you should always consult your physician before starting a fitness regimen.
The tobramycin ophthalmic is used to treat infections of the eye that are susceptible (responsive) to the antibiotic.
The sources used to create this product do not have advice on the use of alcohol with this medication.
http://www.healthcentral.com/mhc/top/001733.cfm

  
 Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method -- Hartmuth et al. 99 ...
Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method -- Hartmuth et al.
Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method
developed a tobramycin affinity-selection method that is generally applicable
http://www.pnas.org/cgi/content/abstract/99/26/16719

  
 Dry Powder versus Intravenous and Nebulized Gentamicin in Cystic Fibrosis and Bronchiectasis . A Pilot Study -- ...
Efficacy of aerosolized tobramycin in patients with cystic fibrosis.
Nebulized antipseudomonal antibiotic therapy in cystic fibrosis: a meta-analysis of benefits and risks.
Intermittent administration of inhaled tobramycin in patients with cystic fibrosis.
http://www.ajrccm.org/cgi/content/full/160/5/1711

  
 NOW Foods - Tobramycin
Empirical treatment of febrile, neutropenic patients with tobramycin and latamoxef.
Seventeen patients with cancer developed calcium, magnesium, and potassium depletion after treatment with aminoglycoside antibiotics, including tobramycin.
Tobramycin is available in special preparations to treat eye infections, alone and in a combination product.
http://www.nowfoods.com/index.php?action=itemdetail&item_id=5457

  
 Tobramycin
Tobramycin is also used in the management of lung infections in patients with cystic fibrosis.
However, this medication may be necessary for the mother.
Tobramycin may be used by infants and children with proper doses.
http://www.wholehealthmd.com/refshelf/drugs_view/0,1524,602,00.html

  
 Tobramycin
Antibacterial, systemic —Amikacin; Gentamicin; Kanamycin; Netilmicin; Streptomycin; Tobramycin
However, this medicine may be needed in serious diseases or other situations that threaten the mother's life.
Pregnancy— Studies on most of the aminoglycosides have not been done in pregnant women.
http://www.healthtouch.com/bin/EContent_HT/drugShowLfts.asp?fname=usp0366.htm&title=Tobramycin&cid=L

  
 Nebcin Online, Description, Chemistry, Ingredients - Tobramycin - RxList Monographs
Patients treated with Nebcin ® (Tobramycin for Injection, USP) and other aminoglycosides should be under close clinical observation, because these drugs have an inherent potential for causing ototoxicity and nephrotoxicity.
RxList only refers patients to online pharmacies certified by VIPPS, Verified Internet Pharmacy Practice Sites, a program administered by the National Association of Boards of Pharmacy which ensures that member pharmacies offering online prescription services are bona fide, fully licensed, and demonstrate "competent Internet/interstate pharmacy practices."
Tobramycin sulfate, a water-soluble antibiotic of the aminoglycoside group, is derived from the actinomycete Streptomyces tenebrarius.
http://www.rxlist.com/cgi/generic3/tobramycin.htm

  
 CSMC NICU: Tobramycin sulfate (Nebcin)
Demonstration of in vitro susceptibility is mandatory, because resistance to tobramycin and the other aminoglycosides may be mediated by the same R-factor.
http://www.neonatology.org/ref/meds/med98.html

  
 PRESS RELEASE: Chris Fowler Racing to Be Sponsored by Chiron -- Fowler credits use of Chiron’s product TOBI® tobramycin ...
Chiron, headquartered in Emeryville, Calif., is a global biotechnology company that addresses human suffering worldwide with more than 50 diverse products to detect, prevent and treat disease.
Chiron BioPharmaceuticals, a business unit of Chiron, produces TOBI® tobramycin solution for inhalation, an inhaled antibiotic indicated for the management of cystic fibrosis (CF) patients.
Chiron BioPharmaceuticals, a business unit of Chiron, produces TOBI® tobramycin solution for inhalation, an inhaled antibiotic indicated for the management of cystic fibrosis (CF) patients with Pseudomonas aeruginosa, a type of bacteria frequently found in the lungs of a person with CF.
http://www.emediawire.com/releases/2004/8/emw146740.htm

  
 PAUMAKO Online Medication & Prescription Resources Search Directory
It is used in the eye to prevent permanent damage, which may occur with certain eye problems.
Tobramycin (toe-bra-MYE-sin) and dexamethasone (dex-a-METH-a-sone) is a combination of an antibiotic and a corticosteroid ( kor-ti-ko-STER-oid).
http://www.paumako.com/search/indexrx.php

  
 Tobradex Online, Description, Chemistry, Ingredients - Tobramycin and Dexamethasone - RxList Monographs
RxList only refers patients to online pharmacies certified by VIPPS, Verified Internet Pharmacy Practice Sites, a program administered by the National Association of Boards of Pharmacy which ensures that member pharmacies offering online prescription services are bona fide, fully licensed, and demonstrate "competent Internet/interstate pharmacy practices."
For information on ordering Tobradex Online, please click the "online pharmacy" link on the blue horizontal navigation bar at the top of every page or click the "Get a Price Quote" Badge on the right side of pages like this one for a more direct route to a specific product.
Tobramycin and dexamethasone ophthalmic suspension and ointment are sterile, multiple dose antibiotic and steroid combinations for topical ophthalmic use:
http://www.rxlist.com/cgi/generic/tobradex.htm

  
 Significant Microbiological Effect of Inhaled Tobramycin in Young Children with Cystic Fibrosis -- Gibson et al. 167 ...
Articles by Gibson, R. Articles by Ramsey, B. American Journal of Respiratory and Critical Care Medicine Vol 167.
Correspondence and requests for reprints should be addressed to Ronald L. Gibson, M.D., Children's Hospital and Regional Medical Center, 4800 Sandpoint Way NE, Mail Stop 3D-4, P.O. Box 5371, Seattle, WA 98105-0371.
Significant Microbiological Effect of Inhaled Tobramycin in Young Children with Cystic Fibrosis
http://ajrccm.atsjournals.org/cgi/content/abstract/167/6/841

  
 Tobi (Tobramycin) Receives Patent In Europe For Lung Infections In Cystic Fibrosis Patients
Tobi (Tobramycin) Receives Patent In Europe For Lung Infections In Cystic Fibrosis Patients
Tobi has been patented in the U.S. and Australia, and patent applications are pending in Canada and Japan.
SEATTLE, WA -- May 31, 2000 -- PathoGenesis Corp. announced it has been granted a European patent for all seventeen European countries for TOBI® (tobramycin solution for inhalation), its inhaled antibiotic for management of cystic fibrosis patients with Pseudomonas aeruginosa lung infections.
http://www.pslgroup.com/dg/1d427a.htm

  
 Clinically Feasible Biofilm Susceptibility Assay for Isolates of Pseudomonas aeruginosa from Patients with Cystic ...
(16 µg/ml versus 8 µg/ml), and tobramycin (4 µg/ml
http://jcm.asm.org/cgi/content/abstract/42/5/1915

  
 Tobramycin sulfate Dosage, Interactions, Side Effects, How to Use
Tobramycin sulfate Dosage, Interactions, Side Effects, How to Use
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Similar to gentamicin and can be used concurrently with carbenicillin.
http://www.healthdigest.org/drugs/tobramycinsulfate.html

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