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Topic: Tianeptine



  
 Tianeptine - Uses And Sides Effects of Tianeptine
Tianeptine medicine should not be used during pregnancy as it may be harmful to the unborn baby.
This means that Tianeptine may be a good choice for drug abusers or elderly depressed patients.
Tianeptine medicine should not be used: With MAO inhibitors (as a rule, there should be an interval of 15 days between a MAOI and Tianeptine treatments) By expectant or nursing mothers By children of less than 15 years of age Should you have any doubt, consult your doctor
http://www.best-home-remedies.com/drugs/tianeptine.htm   (709 words)

  
 Chest : Tianeptine: a new exploratory therapy for asthma.(communications to the editor)(Letter to the Editor) @ ...
Tianeptine: a new exploratory therapy for asthma.(communications to the editor)(Letter to the Editor)
Chest : Tianeptine: a new exploratory therapy for asthma.(communications to the editor)(Letter to the Editor) @ HighBeam Research
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http://static.highbeam.com/c/chest/january012004/tianeptineanewexploratorytherapyforasthmacommunica   (248 words)

  
 InsideBaltimore.com
"This increase produced by tianeptine suggests that hippocampal volume loss in depressed humans could possibly be prevented by antidepressants," Fuchs concluded.
But he cautioned that much more research is needed to tell if tianeptine, let alone different-acting antidepressants, might offer similar protection to people.
But, "mind you, this is one anti-depressant and this is a fairly atypical one" compared to the antidepressants most Americans use, Sapolsky cautioned.
http://www.insidebaltimore.com/news/health/brain-shrinkage1001.shtml   (566 words)

  
 Overcoming the Effects of Stress on Synaptic Plasticity in the Intact Hippocampus: Rapid Actions of Serotonergic and ...
Broqua P, Baudrie V, Laude D, Chaouloff F (1992) Influence of the novel antidepressant tianeptine on neurochemical, neuroendocrinological, and behavioral effects of stress in rats.
Diamond DM, Bennett MC, Stevens KE, Wilson RL, Rose GM (1990) Exposure to a novel environment interferes with the induction of hippocampal primed burst potentiation in the behaving rat.
A combined immunohistochemical and fluorescent retrograde tracing study in the rat brain.
http://www.jneurosci.org/cgi/content/full/22/9/3638   (4905 words)

  
 Novel Pharmacological Approaches to the Treatment of Depression
Enhanced 5-HT uptake was first reported in brain synaptosomes from rats treated either acutely or chronically with tianeptine; it did not result from a reduction in 5-HT release, and was not found upon in vitro addition of the drug to synaptosomal preparations.
A similar study demonstrated a reduction in the time required for recovery of neuronal firing activity following microiontophoretic application of 5-HT in rats treated chronically, but not acutely, with tianeptine.
Only limited clinical data is available for tianeptine.
http://www.acnp.org/G4/GN401000109/CH107.html   (5367 words)

  
 Tianeptine and its enantiomers: effects on spatial memory in rats with medial septum lesions.
The present study explores further the possibility that tianeptine or its enantiomers (S 16190 and S 16191) can enhance either learning or retention in animals in which the hippocampus has been made partially dysfunctional.
PG - 272-81 AB - Tianeptine, an atypical antidepressant that exhibits clinical efficacy in measures of depression and anxiety, has been reported to enhance learning and memory in rats under certain conditions, an effect not observed with other tricyclic antidepressants.
http://www.hvsimage.com/papers/PMID-%2011489464.htm   (291 words)

  
 Tianeptine treatment of bronchial asthma
Neuropharmacologic treatment of bronchial asthma with the antidepressant tianeptine: a double-blind, crossover placebo-controlled study
Sixty-nine of the 82 children with asthma initially enrolled participated in this study.
We studied the effectiveness of tianeptine in treating these patients.
http://www.cancer-help.com/smartcom/tianeptine/tianeptine-5.htm   (179 words)

  
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 Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by ...
Tianeptine is devoid of the classic actions of antidepressants
to most antidepressants, tianeptine is thought to enhance serotonin
The action of the drug was followed across a
http://www.pnas.org/cgi/content/full/98/22/12796   (4991 words)

  
 Tianeptine, a specific serotonin uptake enhancer, decreases ethanol intake in rats -- Daoust et al. 27 (1): 15 -- ...
tianeptine was examined in rats and compared with that of fluoxetine, a
by 12.5% in fluoxetine-treated rats but was not modified by tianeptine.
Tianeptine, a specific serotonin uptake enhancer, decreases ethanol intake in rats
http://alcalc.oxfordjournals.org/cgi/content/abstract/27/1/15   (152 words)

  
 Tianeptine
Tianeptine, a selective enhancer of serotonin uptake in rat brain.
Costa e Silva and colleagues at the Jardim Botanico in Rio de Janeiro, Brazil reported a greater frequency of headaches in the tianeptine group as compared with placebo.
It was even more effective than maprotiline in a group of patients with coexisting depression and anxiety.
http://www.tocatch.info/en/Tianeptine.htm   (849 words)

  
 Influence of food on tianeptine and its main metabolite kinetics -- Dresse et al. 28 (12): 1115 -- The Journal of ...
Despite the changes observed, tianeptine may be given at meal times to improve compliance with treatment.
The trend and extent of changes in the MC5 metabolite parameters were similar to those observed for the parent drug.
The influence of a test meal on the absorption and disposition of tianeptine (Stablon), a new antidepressant, was investigated in 12 healthy subjects in a two-way, randomized, open cross-over study.
http://www.jclinpharm.org/cgi/content/abstract/28/12/1115   (286 words)

  
 article on depression by Richard Brown MD
She had the first good treatment response in her life to tianeptine and has been consistently much better.
She has failed all available classes of antidepressants and mood stabilizers, including lithium, three anticonvulsants and a smattering of other augmenting medications.
The following cases are illustrative examples of patients who have responded to tianeptine.
http://www.smartnutrition.info/depression-picamilon.htm   (2367 words)

  
 TREATMENT OF BRONCHIAL ASTHMA WITH TIANEPTINE
TIANEPTINE was introduced to the market as an antidepressant drug.
This drug enhances the uptake of serotonin (5-HT) by serotonergic axons.
Studies have shown the levels of f-5HT in plasma are increased in symptomatic patients with asthma.
http://www.lechin.com/asthma.htm   (230 words)

  
 RemedyFind: Stablon (Tianeptine) - Tianeptine: Effectiveness Uncertain
Information on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own physician or other medical professionals.
This makes me less certain than I was at the beginning of how effective tianeptine really is.
I find it works brilliantly for my depression and anxiety, and without the side-effects of SSRIs.
http://www.remedyfind.com/review_long.asp?id=5956&review_id=16904   (334 words)

  
 Tianeptine: A New Exploratory Therapy for Asthma -- Lechin et al. 125 (1): 348 -- Chest
Tianeptine: A New Exploratory Therapy for Asthma -- Lechin et al.
also, both of which are greatly annulled by tianeptine, a drug
Lechin, F, van der Dijs, B, Orozco, B, et al Neuropharmacological treatment of bronchial asthma with an antidepressant drug: tianeptine; a double-blind crossover placebo-controlled study.
http://www.chestjournal.org/cgi/content/full/125/1/348   (955 words)

  
 Tianeptine treatment induces regionally specific changes in monoamines
These data suggest that the short-term neural and behavioral actions of tianeptine may be attributable, in part, to alterations of the norepinephrine system.
Tianeptine treatment induces regionally specific changes in monoamines.
Tianeptine treatment induces regionally specific changes in monoamines
http://www.tianeptine.org/tianeptine/tianeptine-monoamines-16.htm   (176 words)

  
 CiteULike: [Efficacy of tianeptine in the treatment of psychasthenia. A study versus placebo]
Interruption of treatment for side-effects concerns the placebo group only (3 versus 0).
Tianeptine is an effective treatment for patients suffering from psychasthenia.
CiteULike: [Efficacy of tianeptine in the treatment of psychasthenia.
http://www.citeulike.org/article/2813   (314 words)

  
 Tianeptine addiction
His addiction to tianeptine was immediate and heavy.
The patient was hospitalised to treat both the addiction to tianeptine and the ongoing major depressive disorder.
Tianeptine was prescribed for a major depressive disorder.
http://www.anti-depressants.com/tianeptine-addict.htm   (256 words)

  
 Tianeptine and alcohol dependence
Similar results were found in an open study carried out on 277 alcoholic patients treated for 1 year.
Tianeptine has been shown to be active in the treatment of depression in patients with history of alcohol abuse or dependence.
The indication of tianeptine should be restricted to the treatment of depressive syndromes, which have a high lifetime prevalence in the alcoholic patient, and which have a noticeable role on the alcoholic relapse.
http://www.tianeptine.org/tianeptine-4.htm   (341 words)

  
 Antidepressant Tianeptine Stablon With Wellbutrin
University experiment the Antidepressant tianeptine stablon with wellbutrin bit-by-bit burlap with focal keratoacanthoma.
Generic Prozac is prescribed for the treatment of depression; obsessive compulsive disorder; panic disorder; bulimia and other eating disorders and obesity.
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http://www.benway-uk.com/antidepressants/Antidepressant-tianeptine-stablon-with-wellbutrin.html   (1383 words)

  
 Molecular Psychiatry - Abstract of article: Neurobiology of mood, anxiety, and emotions as revealed by studies of a ...
These studies have revealed that the neurobiological properties of tianeptine involve the dynamic interplay between numerous neurotransmitter systems, as well as a critical role of structural and functional plasticity in the brain regions that permit the full expression of emotional learning.
Neurobiology of mood, anxiety, and emotions as revealed by studies of a unique antidepressant: tianeptine
Effects of tianeptine on neuronal excitability, neuroprotection, anxiety, and memory have also been found.
http://www.nature.com/mp/journal/v10/n6/abs/4001648a.html   (316 words)

  
 Tianeptine ( Stablon ) : side-effects
Tianeptine does not induce sedation and thus does not disturb the recovery of active life.
Moreover, tianeptine does not disturb the hematologic, renal, hepatic parameters, even in alcoholic patients in the detoxification period.
It does not induce physical or psychological signs of dependence when discontinued, even in alcoholic patients or drug addicts.
http://biopsychiatry.com/tianeptinesideff.htm   (152 words)

  
 Clinical and neurobiological effects of tianeptine and paroxetine in major depression.
Both SSRIs and tianeptine are clinically effective; however, their opposite modes of action challenge the prevailing concepts on the need of enhancement of serotonergic neurotransmission.
Clinical and neurobiological effects of tianeptine and paroxetine in major depression.
To better understand the differences between these two opposite pharmacological modes of action, we compared the changes induced by tianeptine and paroxetine on psychopathology, the hypothalamic-pituitary-adrenocortical (HPA) system, and cognitive functions in a double-blind, randomized, controlled trial including 44 depressed inpatients over a period of 42 days.
http://www.accelerated-learning-online.com/research/clinical-neurobiological-effects-tianeptine-paroxetine-major.asp   (646 words)

  
 considering giving up on tianeptine, switching to paxil
Stimulants such as Ritalin, Adderal et al also tend to be bad choices.
Overwhelmingly, BPD is a nonsensical label slapped on people who are seen as 'difficult', or even patients who are difficult to treat and/or are unresponcive to their treatment will be DX's Borderline by pdocs to preserve their prestige.
There is also some evidence in monkeys that tianeptine helps the hippocampus to regrow.
http://www.urban-living.org/new-398914-10.html   (3154 words)

  
 neopharmacology: Tianeptine and paroxetine in major depressive disorder, with a special focus on the anxious component ...
In a 6-week, double blind trial, the special focus was on anxious symptoms.Both drugs showed good efficacy on depressive symptomatology, assessed with MADRS and HDRS, but no difference was detected between tianeptine and paroxetine, for any assessment criterion.
Tianeptine (37.5 mg/day) and paroxetine (20 mg/day) were compared in a population of depressive patients without past or current history of co-morbid anxiety and/or important anxiolytic treatment.
Tianeptine and paroxetine in major depressive disorder, with a special focus on the anxious component in depression: an international, 6-week double-blind study dagger.
http://www.circuitblue.com/neopharmacology/paroxetine/paroxAnxDepr.html   (231 words)

  
 Avant Labs -> Tianeptine
This fact explains why tianeptine has proven to be a powerful therapeutic tool in controlling asthma.
Tianeptine, a drug that enhances serotonin uptake by platelets and serotonergic axons at the central nervous system (CNS), provoked an abrupt disappearance of asthma attacks.
In the present article, we discuss the peripheral and central nervous system mechanisms that may explain the therapeutic success of tianeptine.
http://forum.avantlabs.com/topic14478.html   (396 words)

  
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 Avant Labs -> Stablon (Tianeptine) Experiences?
That said, I think that tianeptine's ability to heal the damage done by cortisol is unparalleled.
Tianeptine seemed a little sketchy to me cuz it is treated for depression or post traumatic stress (right ?) which I dont have.
I have been researching Stablon (Tianeptine) for quite some time now
http://forum.avantlabs.com/topic13612.html   (1132 words)

  
 Emerging Worlds: Chronic Illness and Viral Infections
GOTTINGEN, Germany -- German researchers say animal studies show a particular anti-depressant effectively restored areas of the brain that were damaged during prolonged stress.
After tianeptine treatment, the research team destroyed the animals to study their brain tissue.
This induced stress in the weaker animals, causing physiological changes in the brain, including reduced brain cell production and shrinkage of the hippocampus, a critical area of the brain associated with memory and learning.
http://www.emergingworlds.com/mc_article.cfm?link=POST_ANTI_DEPRESSANTS_MAY_HELP_REPAIR_BRAIN.htm   (431 words)

  
 Re: HPA Axis and Anti-Cortisol Therapy- tianeptine » Jakeman
I've read quite a bit of positive information in the scientific literature about this drug, but there seems to be a dearth of anecdotal reports.
Re: HPA Axis and Anti-Cortisol Therapy- tianeptine » Jakeman ed_uk 6/25/05
Re: HPA Axis and Anti-Cortisol Therapy- tianeptine » Jakeman Elroy 6/25/05
http://dr-bob.securesites.com/babble/20050622/msgs/518802.html   (377 words)

  
 Fear: tianeptine (Stablon) v selective serotonin reuptake inhibitor citalopram (Cipramil, Celexa)
In comparison, treatment with tianeptine had no effect acutely but also reduced the acquisition of tone conditioning when administered chronically.
CONCLUSIONS: Our findings with citalopram are consistent with the clinical effects of SSRI treatment seen in patients with anxiety disorders, in which anxiety is often increased during early stages of treatment and decreased after several weeks of treatment.
METHODS: We evaluated the effects of acute and chronic treatment with the SSRI citalopram on the acquisition of auditory fear conditioning.
http://www.anti-depressants.com/fear.htm   (278 words)

  
 STABLON - Cheap Prescription Pharmacies Drugs
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 IngentaConnect Efficacy and Safety of Tianeptine in Major Depression: Evidence f...
Keywords: Antidepressants, therapeutic use; Depression, treatment; Paroxetine, therapeutic use; Tianeptine, therapeutic use
Conclusion: Tianeptine appears to be as effective and as safe as paroxetine for the ambulatory treatment of major depression.
Objective: This study was performed to compare the efficacy and safety of tianeptine and paroxetine in the treatment of major depression.
http://www.ingentaconnect.com/content/adis/cns/2002/00000016/00000001/art00005   (381 words)

  
 PsiTri - search results
Comparative study of the therapeutic and adverse effects of two antidepressants dothiepin and mianserin..
Double-blind study of tianeptine versus placebo and imipramine inthe treatment of major depression and depressed bipolar disorder..
Alprazolam SR in the treatment of generalized anxiety: a multicentre controlled study with bromazepam..
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 TIANEPTINE: เภสัชตำรับ 2547
Stop the drug 24-48 hours prior to surgery with general anesthesia.
A washout period of 2 weeks is necessary between treatment with MAOIs and treatment with tianeptine.
A washout period of only 24 hours is required when replacing tianeptine with a MAOIs.
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 All Nations Pharmacy
This medicine should not be used: With MAO inhibitors (as a rule, there should be an interval of 15 days between a MAOI and Tianeptine treatments) By expectant or nursing mothers.
It is provided under the supplying company's terms and conditions and should not replace the advice of your personal physician.
Angiodepressive states observed in the alcoholic undergoing detoxification
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 Questionable amineptine / tianeptine Post?
If a person is sick they probably do not need an ad to make them better.
I personally take Stablon (tianeptine) which has similar reactive metabolites and can also cause liver problems.
This weblog is licensed under a Creative Commons License.
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 Re: TIANEPTINE -Questions
I'm feeling very depressed at the moment but when I feel better I will try to answer your query re Buspar and tianeptine.
Yes, I agree that using Tianeptine with SSRIs seems illogical because of their opposite effects on Serotonin, but I`m sure I read somewhere that Buspar also decrease the Serotonin level and it`s used all the time to augment SSRI`s, though it did nothing for me.
> I have now been on tianeptine 7 days and feel worse-I'm not sure whether to try to ride it out or quit.
http://www.dr-bob.org/babble/20010708/msgs/70095.html   (277 words)

  
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From a clinical point of view, Stablon has demonstrated its superiority to placebo in several double-blind studies.1,2
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 The serotonin uptake-enhancing drug tianeptine suppresses asthmatic symptoms in children: a double-blind, crossover, ...
We studied the effectiveness of tianeptine in treating patients with asthma.
The serotonin uptake-enhancing drug tianeptine suppresses asthmatic symptoms in children: a double-blind, crossover, placebo-controlled study
Studies have shown that levels of free serotonin in plasma are increased in symptomatic patients with asthma.
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 POTENTIALITIES OF A NEW ANTIDEPRESSANT, TIANEPTINE, IN PATIENTS WITH NON-ISCHEMIC VENTRICULAR ARRHYTHMIAS
The effective and safe treatment with Tianeptinewas shown as well as the changes in the patient psychoemotional status at the background of this treatment were assessed in the patients with anxiety and depressive disturbances in combination with ventricular arrhythmias.
The data stimulate a further investigation of the Tianeptine effect in cardiovascular patients that, probably, permits to individualize their treatment and make it more purposeful.
It is important that in no patient, the arrhythmogenic effect of Tianeptic was observed, this fact gives evidence that use of Tianeptine is relatively safe in patients with non-ischemic ventricular arrhtyhmias accompanied by anxious and depressives status.
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 A comparative study of fluoxetine, moclobemide, and tianeptine in the treatment of posttraumatic stress disorder ...
- Thirty-eight patients were assigned to fluoxetine, 35 patients were assigned to moclobemide, and 30 patients were assigned to tianeptine group.
A comparative study of fluoxetine, moclobemide, and tianeptine in the treatment of posttraumatic stress disorder following an earthquake.
The main aim of this study is to compare the efficacy of different class of antidepressant drugs on the PTSD.
http://counsellingresource.com/medications-research/2005/06/22/a-comparative-study-of-fluoxetine-moclobemide-and-tianeptine-in-the-treatment-of-posttraumatic-stress-disorder-following-an-earthquake   (469 words)

  
 Jahrbuch-CD der MPG 2003 - Synaptic plasticity and tianept
The aim of the present study was therefore to investigate the effect of tianeptine on stress-induced structural changes and alterations in cerebral metabolites.
Stress-induced structural and cellular alterations in the hippocampus can contribute to the pathophysiology of depression, The reversal of these alterations may be a mechanism by which antidepressants achieve their therapeutic effect.
It is concluded that these findings provide experimental evidence for recent theories that impairment of neuronal viability and neuroplasticity might be important causal factors in mood disorders, suggesting tianeptine as a potential stimulator of neural resilience.
http://www.mpg.de/forschungsergebnisse/wissVeroeffentlichungen/archivListenJahrbuch/2002/17/publZIM214.html   (168 words)

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