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| | eMedicine - Thrombolysis, Peripheral : Article by Evan J Samett, MD |
 | | Thrombolysis is a reasonable option for patients with acute lower-limb ischemia for the prevention of amputation, with a mortality rate comparable to that of surgical interventions, with improved outcomes. | | | With these criteria, successful thrombolysis was achieved in 41% of patients treated with SK and in 58% of those receiving alteplase. | | | The choice of technique is mostly a personal one that is influenced by personal experience and based on the particular details of the individual patient and the issues related to the medical center or referring clinicians. |
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http://www.emedicine.com/radio/topic861.htm
(9563 words)
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| | New Page 1 |
| | While prehospital thrombolysis should be administered if journey time is greater than 30 minutes and door to needle times are expected to exceed an additional 30 minutes there is no mention of onset of pain to time of call being a restriction to prehospital thrombolysis. | | | and prehospital thrombolysis is supported by evidence over the past 25 years which indicates that the shorter the onset of symptoms to needle time the greater the benefit. | | | If the medical and paramedical community were to introduce a prehospital thrombolysis drug onto UK ambulances, I believe it should be limited to a few selected thrombolytics drugs so that there is continuity in patient care and it would make research easier to perform. |
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http://freespace.virgin.net/samip.thrombolysis/Bjarkoy.htm
(14854 words)
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| | Information for Patients Undergoing Thrombolysis |
| | Thrombolysis is considered a very safe procedure, designed to improve your medical condition and save you having a larger operation. | | | Thrombolysis is a very safe procedure, but there are some risks and complications that can arise. | | | If you are having thrombolysis done as a pre-planned procedure, then you should have plenty of time to discuss the situation with your own GP, your consultant and the radiologist who will be doing the thrombolysis. |
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http://www.rcr.ac.uk/index.asp?PageID=521
(1698 words)
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| | Final Appraisal Determination: Drugs for early thrombolysis in the treatment of acute myocardial infarction |
| | Given the benefits of early administration of thrombolysis on reducing damage to heart muscle and consequently on long-term outcomes, pre-hospital administration of thrombolysis by ambulance paramedics is being gradually implemented in the NHS. | | | Where pre-hospital delivery of thrombolytic drugs is considered a beneficial approach as part of an emergency-care pathway for AMI (for example, because of population geography or the accessibility of acute hospital facilities), the practicalities of administering thrombolytic drugs in pre-hospital settings mean that the bolus drugs (reteplase or tenecteplase) are recommended as the preferred option. | | | It was also considered important that clinicians and organisations delivering pre-hospital thrombolysis should develop clear clinical protocols for the use of thrombolytic drugs, such as those developed by the JRCALC, and adopt robust clinical governance arrangements to monitor the use of and outcomes associated with these drugs. |
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http://www.nice.org.uk/article.asp?a=36672
(6013 words)
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| | Thrombolysis |
| | The procedure is performed by an interventional radiologist, a physician specially trained to perform thrombolysis and similar procedures. | | | Since your doctors already know that there is a problem with your circulation, you may have already experienced an arteriogram or a venogram, a special x-ray examination of the blood vessels. | | | Thrombolysis is a safe, highly effective way of re-establishing circulation blocked by a clot. |
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http://www.radiologyinfo.org/content/interventional/thrombo.htm
(1662 words)
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| | Thrombolysis for acute deep vein thrombosis (Cochrane Review) |
| | Use of thrombolysis or clot dissolving drugs could reduce the long-term complications of post-thrombotic syndrome (pain, swelling, skin discolouration, or venous ulceration) in the affected leg. | | | A similar effect was also seen for any degree of improvement in venous patency. | | | Thrombolysis for acute deep vein thrombosis (Cochrane Review) |
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http://www.cochrane.org/cochrane/revabstr/AB002783.htm
(509 words)
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| | Laser Thrombolysis |
| | Based on these favorable animal studies of laser thrombolysis and approval from the Food and Drug Administration, a pilot study of laser thrombolysis in acute myocardial infarction in humans was performed. | | | The clinical laser for angioplasty and thrombolysis is configured to emit 250µs pulses. | | | Laser thrombolysis is an interventional procedure that removes clot by delivering microsecond pulses via a fluid core catheter. |
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http://omlc.bme.ogi.edu/projects/lt
(4516 words)
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| | Baylor Health Care System: Usefulness of catheter-directed thrombolysis using alteplase in peripheral vascular occlusion |
| | Our early experience with alteplase has demonstrated that it is an effective alternative to urokinase in catheter-directed thrombolysis for peripheral vascular occlusion; however, it is clear that further investigation is warranted in order to determine its optimal dose. | | | This retrospective study of our experience at Baylor University Medical Center using alteplase in catheter-directed thrombolysis for peripheral vascular occlusion was performed to evaluate its efficacy and safety and to establish an optimal dosing regimen. | | | Between January and November 1999, 44 patients (49 encounters) underwent transcatheter therapy with alteplase at Baylor University Medical Center in Dallas. |
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http://www.baylorhealth.edu/proceedings/14_1/14_1_song.html
(2634 words)
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| | Heart Info - Treatment Forms Promote Better Care for Stroke Patients |
| | The study authors noted that thrombolysis treatment numbers remained the same regardless of the form policy -- reflecting the fact that the number of patients who arrived for care within the relevant three-hour window did not change across the two-year period. | | | They noted that in the second year when a form policy was in place, 63 percent of the patients received "perfect treatment" -- as compared with 44 percent in the prior non-form year. | | | However, other more controllable in-hospital procedures did improve with form use. |
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http://www.heartinfo.org/ms/news/527293/main.html
(1073 words)
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| | Myocardial infarction - thrombolysis (No. 52) |
| | NICE 2002/054 NICE issues guidance on the use of drugs for early thrombolysis in the treatment of acute myocardial infarction | | | ASSESSMENT REPORT: Early Thrombolysis for the Treatment of Acute Myocardial Infarction | | | Information for patients: Guidance on the use of drugs for early thrombolysis in the treatment of acute myocardial infarction |
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http://www.nice.org.uk/cat.asp?c=38399
(147 words)
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| | News - Ultrasound Thrombolysis Effective for Peripheral Occlusive Artery Disease: Presented at SIR |
| | Seventy patients received ultrasound thrombolysis alone, 29 received tPA plus ultrasound thrombolysis, and 51 were treated with 3-day thrombolysis therapy plus ultrasound thrombolysis; 128 received adjunct balloon angioplasty. | | | SALT LAKE CITY, UT -- April 3, 2003 -- Ultrasound thrombolysis appears to be equally effective as a single intervention or in combination with tissue plasminogen activator (tPA) for recanalization in patients with peripheral occlusive artery disease (POAD). | | | Percutaneous Mechanical Thrombectomy Combined with Thrombolysis for the Treatment of Deep Venous Thromboses |
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http://docguide.com/news/content.nsf/news/8525697700573E1885256CFD004B9D7B
(579 words)
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| | Post-Thrombolysis Electrocardiogram as aPrognostic Marker of Mortality in Acute |
| | The patients were classified into three groups (as per GUSTO III criteria): 30% improvement - poor response; 30- 70% improvement - moderate response; 70% improvement -good response. | | | Forty-three patients of the 75 (57.1%) with poor response after thrombolysis died within 1 year (36 died within 1 week), indicating a marked change in medium-term prognosis depending on the ECG response after thrombolysis. | | | Seventy-five patients (18.3%) showed poor response after thrombolysis while 421 (58.2%) showed moderate response after thrombolysis and 126 (23.5%) showed good response after thrombolysis. |
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http://indianheartjournal.com/Sept-Oct2004/html/65_post_thrombolysis.htm
(343 words)
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| | Thrombolysis |
| | Treatment of basilar artery thrombosis is generally approached differently from other intracranial thromboses due to the grave prognosis if blood flow is not reestablished. | | | While we aim to treat middle cerebral artery and anterior cerebral artery occlusions within 3-4 hours of symptom presentation using tissue plasminogia activator thrombolysis. |
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http://www.neurosurgery.pitt.edu/endovascular/treatments/thrombolysis.html
(307 words)
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| | Society Of Interventional Radiology - Patients and Public - Vascular Diseases |
| | There is increasing evidence that clot removal via interventional catheter-directed thrombolysis in selected cases of DVT can improve quality of life and prevent the debilitating sequela of post-thrombotic syndrome. | | | While this use to be considered an unusual, long-term sequela, it actually occurs frequently, in as many as 60-70 percent of people, and can develop within two months of developing DVT. | | | Left untreated, a deep vein thrombosis (DVT) can break off and travel in the circulation, getting trapped in the lung, where it blocks the oxygen supply, causing heart failure. |
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http://www.sirweb.org/patPub/DVTOverview.shtml
(528 words)
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| | 2000 GRC on Thrombolysis |
| | Linda Robbie - The leucocyte contribution to endogenous thrombolysis | | | Nobuo Nagai, Univ. of Leuven - Thrombolysis in stroke: a double edged sword | | | Zivin, Univ. of California, San Diego - Stroke Thrombolysis |
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http://www.grc.uri.edu/programs/2000/thromb.htm
(547 words)
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| | Bacchus on Encyclopedia.com |
| | Bacchus Vascular's Trellis Reserve Isolated Thrombolysis System Receives FDA 510(k) Clearance. |
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http://www.encyclopedia.com/html/B/Bacchus.asp
(616 words)
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