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Topic: Tamoxifen



  
 National Cancer Institute - Tamoxifen: Q & A
The decision to take tamoxifen is an individual one: The woman and her doctor must carefully consider the benefits and risks of therapy.
Patients who are concerned about the risks and benefits of tamoxifen or any other medications are encouraged to discuss these concerns with their doctor.
Taking tamoxifen for longer than 5 years is not more effective than 5 years of therapy.
http://www.cancer.gov/cancertopics/factsheet/Therapy/tamoxifen   (1651 words)

  
 High Dose Tamoxifen For Brain Tumors
Following surgery and radiotherapy, this patient received tamoxifen and is generally well 10 years after brain metastases (53).
A positive response to tamoxifen has been observed with other metastatic brain tumors (44, 78).
One isoform of PKC (isoform A) may be of particular importance (6, 18).
http://www.virtualtrials.com/Tamoxifen2.cfm   (2209 words)

  
 Tamoxifen--What Next? -- Gradishar 9 (4): 378 -- The Oncologist
tamoxifen as the therapy of choice for hormone-sensitive ABC.
Effective tamoxifen therapy of breast cancer involves both antiproliferative and pro-apoptotic changes.
Tamoxifen has been the chosen endocrine therapy for
http://theoncologist.alphamedpress.org/cgi/content/full/9/4/378   (3359 words)

  
 Tamoxifen : CancerBACUP
Tamoxifen is most commonly used after surgery for early breast cancer, to reduce the risk of the cancer coming back: in this situation it is known as adjuvant therapy.
Tamoxifen given in this way is known as neo-adjuvant therapy.
The way in which tamoxifen works is quite complicated and not yet fully understood, but its main function is as an anti-oestrogen drug.
http://www.cancerbacup.org.uk/info/tamoxifen.htm   (1923 words)

  
 Novaldex, Tamoxifen - Chemotherapy Drugs
Tamoxifen may be prescribed in women with ductal carcinoma in situ (DCIS) who have completed surgery and radiation therapy.
You will be checked regularly by your health care professional while you are taking tamoxifen, to monitor side effects and check your response to therapy.
Your fertility, meaning your ability to conceive or father a child, may be affected by tamoxifen.
http://www.chemocare.com/bio/bio.sps?iBiographyID=9175   (1288 words)

  
  DukeMedNews Slightly Increased Risk of Ischemic Stroke Found with Tamoxifen
Because of the risk of thromboembolism, tamoxifen could theoretically be associated with higher risk of arterial obstruction in the brain and could cause ischemic stroke -- versus a hemorrhagic stroke in which a vessel bursts and bleeds into the brain, the researchers said.
The frequency of all strokes was 1.06 percent with tamoxifen versus 0.76 percent in controls.
The Duke team performed a "meta-analysis" review of tamoxifen research conducted since 1980 in which patients were randomized to either tamoxifen versus placebo or tamoxifen versus other therapies.
http://www.dukemednews.org/news/article.php?id=8194   (1046 words)

  
 Tamoxifen - A Major Medical Mistake?
In rats, a tamoxifen metabolite (a breakdown compound almost similar in structure to the original) was found to influence the uterus to be more receptive to estrogen.
Tamoxifen (brand name Nolvadex) is now the most widely prescribed cancer medication in the world.
Starting in the 1970's oncologists began using tamoxifen to treat women with cancer, often in combination with other drugs, radiation or surgery such as lumpectomy and mastectomy, with modest success.
http://www.all-natural.com/tamox.html   (4615 words)

  
 BBC NEWS Health Medical notes Tamoxifen
This means it can work like oestrogen replacement therapies and protect the patient against osteoporosis - the brittle-bone condition that affects many post-menopausal women.
It is possible that the cancers were just delayed rather than prevented; the drug may not work for certain sub-groups of women; and the halting the study early may impede efforts to get a clear picture of the risks of taking Tamoxifen.
The drug, first developed in the UK, is cheap and helps prevent the cancer coming back after the initial surgery to remove a tumour.
http://news.bbc.co.uk/go/rss/-/1/hi/health/medical_notes/84281.stm   (584 words)

  
 Tamoxifen Information from Drugs.com
Your pharmacist has additional information about tamoxifen written for health professionals that you may read.
You should discuss with your doctor the risks and benefits associated with the use of tamoxifen.
http://www.drugs.com/tamoxifen.html   (1143 words)

  
 [No title]
The incidence of all other adverse reactions was similar in the 2 treatment groups with the exception of thrombocytopenia where the incidence for Tamoxifen Citrate was 10% versus 3% for placebo, an observation of borderline statistical significance.
Continued clinical studies have resulted in further information which better indicates the incidence of adverse reactions with Tamoxifen Citrate Tablets as compared to placebo.
In the ongoing NSABP study B-14, women with axillary nodenegative breast cancer were randomized to 5 years of Tamoxifen Citrate 20 mg/day or placebo following primary surgery.
http://www.druginfonet.com/tamoxfen.htm   (4224 words)

  
 Tamoxifen
Tamoxifen may increase the chance of having a stroke.
This means that tamoxifen is working and the pain should soon decrease.
http://www.overlakehospital.staywellknowledgebase.com/26,588   (1838 words)

  
 Policy on Tamoxifen (Nolvadex)
Indeed, premenopausal women taking tamoxifen are at risk for bone loss in the spine and hip of 1.7% annually.
Our own risk-benefit analysis of tamoxifen suggests that women taking tamoxifen bear the risk while the benefit accrues to the manufacturer and the researchers.
A similar trial in Scotland supported the NSABP findings: survival was 70% in women taking tamoxifen for five years and only 62% in those taking the drug longer than five years.
http://www.bcaction.org/Pages/LearnAboutUs/TamoxifenPolicy.html   (2064 words)

  
 MedlinePlus Drug Information: Tamoxifen
Talk to your doctor about the possible risks of using this drug for your condition.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
tell your doctor and pharmacist if you are allergic to tamoxifen or any other drugs.
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682414.html   (692 words)

  
 Trait Anxiety and Tamoxifen Effects on Bone Mineral Density and Sex Hormone- Binding Globulin -- Cameron et al. 64 (4): ...
Tamoxifen reduces bone turnover and prevents lumbar spine and proximal femoral bone loss in early postmenopausal women.
tamoxifen was associated with greater lumbar spine BMD at 3,
OBJECTIVE: Tamoxifen therapy preserves BMD of the lumbar spine
http://www.psychosomaticmedicine.org/cgi/content/full/64/4/612   (4538 words)

  
 Tamoxifen and Breast Cancer
Tamoxifen may also increase bone density, which can slow the development of osteoporosis (bone loss) and reduce the incidence of bone fractures.
Ask your doctor which over-the-counter medications you can take.
Always contact your doctor if you have questions about your personal situation.
http://www.cchs.net/health/health-info/docs/2600/2616.asp?index=9785   (1678 words)

  
 Patient Reluctance Toward Tamoxifen Use for Breast Cancer Primary Prevention -- Port et al. 8 (7): 580 -- Annals of ...
Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial.
tamoxifen was much less effective in reducing recurrence and
Prevention with tamoxifen or other hormones versus prophylactic surgery in BRCA1/2-positive women: a decision analysis.
http://www.annalssurgicaloncology.org/cgi/content/full/8/7/580   (3216 words)

  
 Tamoxifen
And while you are on any medicine, it's important to see your doctor regularly to make sure that the drug is working well for you, and to discuss other appropriate options.
In this section you'll learn more about whether tamoxifen might be a good treatment choice for YOU.
Tamoxifen is a powerful drug that works against hormone-receptor-positive breast cancer.
http://www.breastcancer.org/tre_sys_tamox_idx.html   (338 words)

  
 Tamoxifen adverse reactions
However, an ophthalmological assessment every two years or earlier in case of visual complaints for patients taking tamoxifen as an adjuvant therapy remains useful, because the oncological therapy can be adjusted if serious ocular complications arise.
Neurologic evaluation failed to provide an explanation for the ocular findings which resolved completely after cessation of tamoxifen therapy.
Specific ocular complications, namely retinopathy, keratopathy and optic neuritis, have been described in women being treated with tamoxifen for metastatic breast cancer or taking this drug as an adjuvant postoperative therapy.
http://www.whale.to/drugs/tamoxifen.html   (291 words)

  
 Tamoxifen-Induced Female Androgenetic Alopecia in a Patient with Breast Cancer -- Ayoub et al. 126 (9): 745 -- Annals ...
in a patient receiving adjuvant tamoxifen therapy for stage
Tamoxifen has been reported to induce changes in hair
Gabriel N. Hortobagyi, MD 1 May 1997
http://www.annals.org/cgi/content/full/126/9/745-a   (415 words)

  
 Tamoxifen
Dinner to dream she call a Tamoxifen id. Work done who needs somebody called dr then cut.
Needs to work, to give each dream she wants bad.
Without a Tamoxifen is week, theyll all be that was such.
http://drug-overdose.net/mad/Tamoxifen   (302 words)

  
 Tamoxifen - Wikipedia, the free encyclopedia
4-hydroxytamoxifen is a form of the drug tamoxifen that is made by the body after taking tamoxifen.
It is also available as a generic drug in a number of countries.
Tamoxifen is an oral selective estrogen receptor modulator which is used in breast cancer treatment, and is currently the world's largest selling breast cancer treatment.
http://en.wikipedia.org/wiki/Tamoxifen   (215 words)

  
 Breast Cancer Drug Tamoxifen Helps Heart
The breast cancer patients had a 50% reduced risk of heart attack or chest pain, compared with the women with other cancers.
Breast cancer patients who used tamoxifen in the past had a 50% reduced risk of heart disease.
Tamoxifen may also be prescribed to prevent breast cancer in women at high risk for the disease.
http://www.webmd.com/content/article/100/105822.htm   (460 words)

  
 Tamoxifen Information
The clinical review will be posted as soon as it is available.
This new indication for tamoxifen, which has been used as a breast cancer treatment for more than 20 years, resulted from a recent study of the drug, conducted by the National Cancer Institute (NCI), in women who were judged to be at increased risk of breast cancer.
The data also showed that tamoxifen treatment did not completely eliminate breast cancer risk, and that its longer term effects are not known.
http://www.fda.gov/cder/news/tamoxifen   (257 words)

  
 Genes, Antidepressants Can Affect Tamoxifen
The researchers wanted to see which variations affected blood levels of tamoxifen.
Tamoxifen has been used for more than 20 years to treat breast cancer.
The answer may lie in the women's genes -- and in their medicine chests.
http://my.webmd.com/content/article/99/105077.htm   (418 words)

  
 tamoxifen - Cancer information on MedicineNet.com
MedicineNet Home > Medications A-Z List > Cancer Home Page > tamoxifen
Tamoxifen also is used for the treatment of women following surgery and radiation for a less common type of breast cancer called ductal carcinoma in situ (DCIS or intraductal carcinoma).
PRESCRIBED FOR: Tamoxifen is used for the treatment of invasive breast cancer, the most common type of breast cancer, following surgery and/or radiation and for preventing invasive breast cancer in women at high risk for developing it.
http://www.medicinenet.com/tamoxifen/article.htm   (436 words)

  
 Tamoxifen Book List
Tamoxifen : Molecular Basis of Use in Cancer Treatment and Prevention
" researchers working on clinical trials reported that tamoxifen lowered the incidence of new breast cancers by 45 percent among women at high risk of developing the disease" - ABC News, 21 Apr 1998.
This page presents books relevant to understanding cancer and specialized treatment of breast cancer using tamoxifen.
http://www.a-ten.com/alz/cancer2.htm   (295 words)

  
 How Tamoxifen Works
Tamoxifen may even cause breast cancer cells to destroy themselves, a process called apoptosis, or programmed cell death.
Tamoxifen may also take the place of natural estrogen in the receptors of healthy breast cells.
(This is called an "anti-angiogenic" effect, one that slows or stops blood vessel development.) Although this tamoxifen action would never be enough to halt the development of all blood vessels, it may be able to starve out some of the cancer cells.
http://www.breastcancer.org/tre_sys_tamox_howWrk.html   (520 words)

  
 Nolvadex Online, Description, Chemistry, Ingredients - Tamoxifen Citrate - RxList Monographs
See WARNINGS: Effects on the Uterus-Endometrial Cancer and Uterine Sarcoma.
Tamoxifen citrate has a molecular weight of 563.62, the pKa’ is 8.85, the equilibrium solubility in water at 37
Each tablet contains 15.2 mg of tamoxifen citrate which is equivalent to 10 mg of tamoxifen.
http://www.rxlist.com/cgi/generic/tamox.htm   (372 words)

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