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 The {beta}1 subunit of the Ca2+-sensitive K+ channel protects against hypertension -- Nelson and Bonev 113 (7): 955 -- ...
Vasoregulation by the ß1 subunit of the calcium-activated potassium channel.
subunit enhances the role of the Ca spark–BK channel negative feedback mechanism in limiting vasoconstriction and effectively provides protection against diastolic hypertension.
Functional role of the ß subunit of high conductance calcium-activated potassium channels.
http://www.jci.org/cgi/content/full/113/7/955   (1593 words)

  
 Interaction of GABA Receptor/Channel {rho}1 and {gamma}2 Subunit -- Ekema et al. 43 (7): 2326 -- Investigative ...
subunit from the brain and spinal cord or from exogenous expression in oocytes.
Subunit from the Rat Brain and Spinal Cord
subunit antibody in the brain and spinal cord, but not in the
http://www.iovs.org/cgi/content/full/43/7/2326   (4136 words)

  
 Postsynaptic clustering of major GABAA receptor subtypes requires the
2 subunit and for gephyrin under the three conditions: mock treated, gephyrin sense treated and antisense treated (n = 3 independent cultures for each condition and each antigen).
In contrast, gephyrin immunoreactivity in the brainstem appeared only slightly reduced (data not shown), consistent with the notion that it is mostly associated with abundant glycinergic synapses in this brain area, and that glycinergic synapses seem not to be affected by the loss of clustered GABA
Quantification of clusters in antisense experiments was done analogously for the
http://www.nature.com/cgi-taf/DynaPage.taf?file=/neuro/journal/v1/n7/full/nn1198_563.html   (4824 words)

  
 Calcium Channel beta Subunit Promotes Voltage-Dependent Modulation of alpha 1B by Gbeta gamma -- Meir et al. 79 (2): ...
subunits is to enhance the coupling between depolarization and
The CFL represents the probability of the channel opening before a given time (see Materials and Methods).
3 subunit cDNA construct did not prevent the expression
http://www.biophysj.org/cgi/content/full/79/2/731   (5419 words)

  
 Endothelial K+ channel lacks the Ca2+ sensitivity-regulating {beta} subunit -- PAPASSOTIRIOU et al. 14 (7): 885 -- The ...
subunits, we transfected the ß subunit into a human endothelial
Data points were fitted by use of the Boltzmann equation.
experiments in which ectopic expression of the ß subunit
http://www.fasebj.org/cgi/content/full/14/7/885   (4821 words)

  
 The transmembrane domain of subunit b of the Escherichia coli F1FO ATP synthase is sufficient for H+-translocating ...
subunits does not affect the function of the Escherichia coli ATP synthase.
subunit b is sufficient, as well as necessary, for H
the very C-terminus of subunit b interacts with F
http://content.febsjournal.org/cgi/content/full/271/14/3036   (3453 words)

  
 Ca2+ Channel beta 3 Subunit Enhances Voltage-Dependent Relief of G-Protein Inhibition Induced by Muscarinic Receptor ...
C, Summary of mean voltage-dependent facilitation before and after G-protein subunit coexpression.
when no exogenous G-protein subunits were expressed to 57 ± 8%
channels to determine the G-protein subunit mediating voltage-dependent
http://www.jneurosci.org/cgi/content/full/18/13/4883   (4195 words)

  
 Chaperone-Subunit-Usher Interactions Required for Donor Strand Exchange during Bacterial Pilus Assembly -- Barnhart et ...
Periplasmic chaperone recognition motif of subunits mediates quaternary interactions in the pilus.
neighboring subunit fused to their C terminus (Fig.
The chaperone interacts with pilus subunits in a mechanism
http://jb.asm.org/cgi/content/full/185/9/2723   (5400 words)

  
 Embryonic Expression of the Putative gamma  Subunit of the Sodium Pump Is Required for Acquisition of Fluid Transport ...
subunit, although not an integral component of Na -ATPase, is an important determinant of active cation transport
However, Na -ATPase enzymatic activity was unaffected as determined by a direct
The sodium/potassium pump, Na -ATPase, is generally understood to function as a heterodimer of two subunits, a catalytic
http://www.jcb.org/cgi/content/abstract/139/6/1545   (684 words)

  
 Energy-driven subunit rotation at the interface between subunit a and the c oligomer in the FO sector of Escherichia ...
subunit rotation by the approach used here, only one or two turnovers
3 and 4 demonstrate that such limited subunit rotation can
to subunit a may be in the deprotonated state.
http://www.pnas.org/cgi/content/full/98/15/8519   (4605 words)

  
 Alternative Splicing of the beta 4 Subunit Has alpha 1 Subunit Subtype-Specific Effects on Ca2+ Channel Gating -- ...
We have isolated from human spinal cord a novel alternatively
4 subunit; alternative splicing; N terminus; calcium channel; gating; voltage clamp; spinal cord
Unique modulation of L-type Ca2+ channels by short auxiliary {beta}1d subunit present in cardiac muscle
http://www.jneurosci.org/cgi/content/abstract/22/5/1573   (453 words)

  
 A Novel Plant Ferritin Subunit from Soybean That Is Related to a Mechanism in Iron Release -- Masuda et al. 276 (22): ...
Notably, a leucine is found at a similar position in one
subunit identified in this study was not susceptible to cleavage.
of the cowpea ferritin subunits to that of the leucine at position
http://www.jbc.org/cgi/content/full/276/22/19575   (4195 words)

  
 GATA-1 and GATA-4 Transactivate Inhibin/Activin {beta}-B-Subunit Gene Transcription in Testicular Cells -- Feng et al. ...
and ß-B subunits during the cycle of the rat seminiferous epithelium.
same approach, the basal promoter for the 4.8-kb ß-B- subunit gene transcripts was further analyzed.
Inhibins and activins have been characterized as dimeric glycoproteins sharing
http://mend.endojournals.org/cgi/content/full/14/11/1820   (7934 words)

  
 Mapping of Subunit-Subunit Contact Surfaces on the beta ' Subunit of Escherichia coli RNA Polymerase -- Katayama et al. ...
subunit contact site by analysis of the contact-dependent cleavage
subunit is associated (holoenzyme form) or not (core enzyme form).
subunits, the core enzyme reconstitution experiment was carried
http://www.jbc.org/cgi/content/full/275/5/3583   (4592 words)

  
 Disparate Roles for the Regulatory A Subunit Isoforms in Arabidopsis Protein Phosphatase 2A -- Zhou et al. 16 (3): 709 ...
among the A subunits, suggesting extensive overlap in the expression
Silverstein, A.M., Barrow, C.A., Davis, A.J., and Mumby, M.C. Actions of PP2A on the MAP kinase pathway and apoptosis are mediated by distinct regulatory subunits.
A subunit expression by immunoblotting using a polyclonal antiserum
http://www.plantcell.org/cgi/content/full/16/3/709   (6557 words)

  
 Archaeal Large Ribosomal Subunit Interactive Tour/UMASS Amherst
Additionally, not only did they elucidate a high resolution structure of the large subunit rRNA and most of its associated proteins, but they also soaked in analogs of substrates and solved structures with these bound in the subunit.
A Brief Introduction to the Large Subunit Structure
The subunit was purified from a rather obscure organism, the archaea Haloarcula marismortui.
http://www-unix.oit.umass.edu/~wdecatur/ribosome   (1615 words)

  
 Protein subunit - Wikipedia, the free encyclopedia
For example, ATP synthase has a type of subunit called α.
In some protein assemblies, one subunit may be referred to as a "regulatory subunit" and another as a "catalytic subunit." An enzyme composed of both regulatory and catalytic subunits when assembled is often referred to as a holoenzyme.
Larger groups of subunits can also the specified, like α
http://en.wikipedia.org/wiki/Protein_subunit   (222 words)

  
 The Repertoire of Na,K-ATPase alpha and beta Subunit Genes Expressed in the Zebrafish, Danio rerio -- Rajarao et al. 11 ...
subunits suggest that many of the isoenzymes are also
1 subunit is the only isoform that appears to be expressed
4 subunit has not as yet been identified.
http://www.genome.org/cgi/content/full/11/7/1211   (4409 words)

  
 Methylation of the Protein Phosphatase 2A Catalytic Subunit Is Essential for Association of B{alpha} Regulatory Subunit ...
Methylation of the Protein Phosphatase 2A Catalytic Subunit Is Essential for Association of B
In this study, both genetic and biochemical approaches
subunit but not the amount that could be coimmunoprecipitated
http://www.molbiolcell.org/cgi/content/abstract/12/1/185   (745 words)

  
 Archives of Pathology & Laboratory Medicine: Immunoexpression of inhibin (alpha) subunit, inhibin/activin (beta A) ...
Ovarian cancer is the fourth most common cancer and the leading cause of death from gynecologic malignancy.1 Despite considerable efforts to elucidate the exact mechanisms by which growth and proliferation of both normal and malignant ovarian cells are regulated in the human ovary little is known.
Conclusions.-The results of immunohistochemical analysis, together with literature review, suggest that inhibin alpha subunit may be a useful diagnostic marker for sex cordstromal tumor of the ovary.
The present study aimed to determine what combination of these mAbs may be useful for the differential diagnosis of sex cord-stromal tumors of ovary.
http://www.findarticles.com/p/articles/mi_qa3725/is_200004/ai_n8890619   (655 words)

  
 Human protein: P30154 - Serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, beta isoform (PP2A, ...
Defects in PPP2R1B might be a cause of some lung and colorectal cancers.
Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules.
It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits.
http://harvester.embl.de/harvester/P301/P30154.htm   (1720 words)

  
 Applied Genetics News: Shiga Subunit Replaces Adjuvant
This could represent an important improvement over existing therapies due to the relatively large number of B cells compared to the number of dendritic cells.
In addition to dendritic cells, the scientists found that the B- subunit can also induce antigen presentation in human B cells that in fact express the B-subunit receptor.
http://www.findarticles.com/p/articles/mi_m0DED/is_2_21/ai_65803111   (411 words)

  
 ATP Synthase: Fo Structures
Rastogi VK and Girvin ME. (1999) "Structural changes linked to proton translocation by subunit c of the ATP synthase." Nature 402: 263 PubMed [1C99.pdb]
Thus, the ring model and its association with subunit a are modeled extensions of the actual structure determinations.
Arg 210 is known to be involved in the proton transfer.
http://info.bio.cmu.edu/Courses/BiochemMols/Channels/1c17.htm   (763 words)

  
 PKA beta (catalytic subunit) (phospho S338) antibody (ab5816) datasheet
Phosphorylation of serine 338 plays a key role in stabilizing PKA and activating its substrates, and hence mediating its biological functions.
Customer reviews (feedback) regarding PKA beta (catalytic subunit) (phospho S338) antibody
But please do contact us if you would like any reassurance!
http://www.abcam.com/?datasheet=5816   (794 words)

  
 Mission-Swan Subunit Duty Station
The Mission/Swan Subunit is very interesting for anyone pondering the challenges to grizzly bear recovery in the lower 48 states.
For this reason, people applying for work in our subunit must have excellent map reading and orienteering skills and have strong public outreach and communications skills.
Working in this landscape crews will gain a lot of first hand knowledge of these challenges including habitat degradation, increasing human development, food attractants that create mortality sinks on private lands, difficult highway crossings, habitat fragmentation, and human misunderstanding of bear ecology and behavior.
http://www.nrmsc.usgs.gov/NCDE_dutystationMS.htm   (1071 words)

  
 AV/C CA Subunit Specification
The model describes a generic functional block and command set that is compatible with multiple conditional access and broadcast systems.
This document is the specification for an AV/C CA subunit.
The CA Subunit provides the core functionality that is required to descramble selected services.
http://www.1394ta.org/Technology/Specifications/Descriptions/AVC_CA_Subunit_10.htm   (94 words)

  
 Protein phosphatase 2A subunit assembly: the catalytic subunit carboxy terminus is important for binding cellular B ...
Mutational analysis of the carboxy terminus in vivo was facilitated by efficient immunoprecipitation of trimeric PP2A holoenzyme via an epitope-tagged catalytic subunit.
Substitution of alanine at position 304 or phenylalanine at position 307 did not dramatically reduce B subunit binding or phosphatase activity in vitro, yet the latter substitutions are not found in naturally occurring PP2As.
Replacing catalytic subunit threonine 304 or tyrosine 307 with a negatively charged amino acid abolished binding of the B subunit to the dimeric enzyme core and altered substrate specificity.
http://www.nature.com/cgi-taf/DynaPage.taf?file=/onc/journal/v15/n8/abs/1201259a.html   (389 words)

  
 InterPro: IPR008193 DNA-directed RNA polymerase, 13 to 16 kDa subunit
In archaea, there is generally a single form of RNA polymerase which also consists of an oligomeric assemblage of 10 to 12 polypeptides.
Davis J.A. Takagi Y. Kornberg R.D. Asturias F.A. Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction.
Small subunits of about 13 to 16 kDa are found in all three types of eukaryotic polymerases and in archaeal polymerase.
http://www.ebi.ac.uk/interpro/IEntry?ac=IPR008193   (3035 words)

  
 At5g52340 - exocyst subunit EXO70 family protein
At5g52340 is a homologue of At2g28640 (exocyst subunit EXO70 family protein) from Arabidopsis thaliana.
At5g52340 is a homologue of At2g39380 (exocyst subunit EXO70 family protein) from Arabidopsis thaliana.
At5g52340 is a homologue of At2g28650 (exocyst subunit EXO70 family protein) from Arabidopsis thaliana.
http://www.ihop-net.org/UniPub/iHOP/gg/20584.html   (256 words)

  
 CanB2 - Calcineurin B subunit, isoform 2
Requirement of the calcineurin subunit gene canB2 for indirect flight muscle formation in Drosophila.
The gene canB2, which encodes the essential regulatory subunit of calcineurin, was identified as a suppressor group, demonstrating that the screen was capable of identifying genes relevant to calcineurin function.
CanB2 is a homologue of Ppp3r1 (Calcineurin B subunit isoform 1) from Mus musculus.
http://www.pdg.cnb.uam.es/UniPub/iHOP/gg/69048.html   (174 words)

  
 Upstate - Product #14-440 - PKA, catalytic subunit, recombinant ( 14440 )
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Recombinant human full length PKA, catalytic subunit type alpha, untagged
Click here to set your country preference and view prices.
http://www.upstate.com/browse/productdetail.asp?ProductID=14-440   (162 words)

  
 Large conformational changes of the varepsilon subunit in the bacterial F1F0 ATP synthase provide a ratchet action to ...
The F Subunit of Thermus thermophilus V1-ATPase Promotes ATPase Activity but Is Not Necessary for Rotation
The structure of bovine IF1, the regulatory subunit of mitochondrial F-ATPase
F0F1-ATPase/Synthase Is Geared to the Synthesis Mode by Conformational Rearrangement of {epsilon} Subunit in Response to Proton Motive Force and ADP/ATP Balance
http://www.pnas.org/cgi/content/abstract/98/12/6560   (741 words)

  
 Three Distinct Classes of the {alpha}-Subunit of the Nuclear Pore-targeting Complex (Importin-{alpha}) Are ...
subunit of the nuclear pore-targeting complex, and their tissue-specific expression.
Weis K, Dingwall C, Lamond AI (1996) Characterization of the nuclear protein import mechanism using Ran mutants with altered nucleotide binding specificities.
Görlich D, Kostka S, Kraft R, Dingwall C, Laskey RA, Hartmann E, Prehn S (1995) Two different subunits of importin cooperates to recognize nuclear location signals and bind them to the nuclear envelope.
http://www.jhc.org/cgi/content/full/47/3/363   (3832 words)

  
 Conformational Dynamics of the F1-ATPase {beta}-Subunit: A Molecular Dynamics Study -- Böckmann and ...
to neighbored subunits or whether the open ß-subunit
http://www.biophysj.org/cgi/content/abstract/85/3/1482   (211 words)

  
 Video University: Video University Forums: Tech Q & A: AV/C Subunit
I am trying to capture from my camcorder and I got a message to check the internet for AV/C subunit driver.
: I am trying to capture from my camcorder and I got a message to check the internet for AV/C subunit driver.
Video University: Video University Forums: Tech Q and A: AV/C Subunit
http://www.videouniversity.com/forums/gforum.cgi?post=54854   (129 words)

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