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| | Memory uses separate information pathways |
 | | The signal pathways ultimately meet in the so-called subiculum of the brain, from which information from the hippocampus is passed on to other areas of the brain, such as the cerebral cortex. | | | In order to determine whether the organisation of the hippocampal area of the brain is similar in rats and in humans, further research will be carried out on human test subjects to establish what different types of information correspond to the various pathways. | | | This has been demonstrated by means of anatomical and electrical measurements of the hippocampus and the adjacent cerebral cortex of laboratory rats. |
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http://www.eurekalert.org/pub_releases/1999-11/NOfS-Musi-081199.php
(411 words)
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| | OUP: Appendix 04 |
| | The subiculum proper has been, and probably should be, viewed primarily as a source of efferents from the septo-hippocampal system. | | | There are, then, three major points through which the septo-hippocampal system talks with the outside world: the entorhinal cortex, the septum, and the subiculum. | | | While the anatomy of the dorsal and ventral tegmental nuclei is very uncertain at present, it appears that they represent a number of short and long loops which can return information to the mammillary bodies. |
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http://www.oup.co.uk/academic/medicine/medical_updates/neuropsych_anxiety/app04
(12416 words)
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| | Research - Gabriel Lab |
| | Training is identical to the procedure used in the ventral subiculum project (acquisition of discriminative avoidance behavior followed by exposure to the three extinction conditions). | | | A follow up to the ventral subiculum project, this study further investigates the role of the nucleus accumbens in the contextual modulation of behavior. | | | Effects of nucleus accumbens shell lesions on behavioral and neuronal responses to context change during extinction of discriminative avoidance behavior |
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http://soma.npa.uiuc.edu/labs/mgabriel/research.php?doc=0002
(170 words)
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| | Research - Gabriel Lab |
| | Effects of ventral subiculum lesions on behavioral and neuronal responses to context change during extinction of discriminative avoidance behavior | | | To test this hypothesis, rabbits were given electrolytic or sham lesions of the ventral subiculum and were implanted with fixed position electrodes for the recording of neuronal activity in the following areas: area 24 (anterior cingulate cortex), area 29 (posterior cingulate cortex), nucleus accumbens, basolateral amygdala, and ventral subiculum (shams only). | | | In intact animals, extinction of avoidance behavior occurs more quickly when extinction of discriminative avoidance behavior is given in a novel context compared to when extinction takes place in the original training context. |
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http://soma.npa.uiuc.edu/labs/mgabriel/research.php?doc=0001
(298 words)
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| | Age-related changes in the subiculum of Macaca mulatta: synaptic density. |
| | Dendritic spines and synapses were quantitated in the subiculum of 12 Macaca mulatta from 7 to 29 years of age. | | | Dendritic spines were analyzed in six dendritic foci of pyramidal neurons impregnated by the Golgi-Cox method. | | | Age-related changes in the subiculum of Macaca mulatta: synaptic density. |
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http://www.arclab.org/medlineupdates/abstract_3972044.html
(242 words)
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| | Transregional Research Centre Mesial Temporal Lobe Epilepsies (SFB/TR3) |
| | However, the enhanced excitability of the subiculum is hitherto not understood. | | | During the first grant period we showed that changes on the synaptic level rather than network alterations are the critical factor in the epileptogenesis of the subiculum. | | | This hypothesis was recently confirmed in a study on hippocampal brain slices of patients with TLE. |
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http://www.meb.uni-bonn.de/epileptologie/sfb-tr3/b4.htm
(211 words)
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| | Dr. Shane M. O'Mara - Publications - 2000 |
| | Subiculum Of The Freely-Moving Rat During A Pellet-Chasing Task. | | | Interactions Between Paired-Pulse Facilitation, Low-Frequency Stimulation And Behavioral Stress In The Pathway From Hippocampal Area CA1 To The Subiculum: Dissociation Of Baseline Synaptic Transmission From Paired-Pulse Facilitation And Depression Of The Same Pathway. | | | Anderson, M., Commins, S. and O'Mara, S.M. The Effects Of Low Frequency And Two-Pulse Stimulation Protocols On Synaptic Transmission In The CA1-Subiculum Pathway In The Anaesthetized Rat. |
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http://www.tcd.ie/Psychology/Shane_O_Mara/2000.html
(244 words)
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| | [No title] |
| | Subiculum => fimbria of fornix => fornix => mammillary bodies => MTT => anterior nucleus of thalamus => cingulate cortex. | | | Entorhinal cortex => diffuse connections throughout hippocampal formation => subiculum => fornix => mammillary bodies. | | | Click a link above to display the answer. |
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http://medicine.creighton.edu/medschool/2006/Review/Neuro/Limbic_a.html
(187 words)
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| | Neuroscience Wiki: Subiculum |
| | The subiculum is the transition between the hippocampus and the ParahippocampalGyrus and it gradually changes from three layers to six. | | | Synaptic interactions among excitatory afferents to nucleus accumbens neurons: hippocampal gating of prefrontal cortical input. | | | Signal Switching in the Brain (commentary/summary of Cooper et al. |
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http://www.ifi.unizh.ch/~andel/neurowiki/nw.cgi?action=browse&diff=1&id=Subiculum
(341 words)
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| | IBNS - Abstracts Submitted For 2006 |
| | Numerous studies showed that functional interactions between dopaminergic neurotransmission and glutamatergic neurotransmission in the rat nucleus accumbens are involved in the development of environmentally adapted behaviours. | | | In the present study, we characterize the role of the dorsal hippocampus and the ventral subiculum in the locomotor response induced by activation of the D1-like receptors alone and in the locomotor response produced by activation of both D1-like and D2-like receptors in the nucleus accumbens. | | | Furthermore, administration of lidocaine in the dorsal hippocampus increased the locomotor response induced by co-infusion of SKF 38393 + quinpirole, while application of lidocaine in the ventral subiculum decreased it. |
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http://www.ibnshomepage.org/FullAbstract.asp?ID=69
(328 words)
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| | Michael Anderson - Current Research |
| | These experiments are the first comprehensive investigation into the functions of the subiculum in vivo. | | | The overall aim of my research is directed at investigating the physiology and functions of the subiculum. | | | Electrophysiological and lesion studies have demonstrated that the hippocampal formation is vital for normal memory function. |
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http://www.tcd.ie/Psychology/Michael_Anderson/research.html
(443 words)
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| | [No title] |
| | I-11 Three-dimensional organization of the hippocampal formation and fornix The fornix, a C-shaped structure, is the major efferent pathway of the hippocampal formation. | | | The postcommissural fornix arises mainly from the subiculum and terminates predominantly in the mammillary body on the same side. | | | The subiculum, upon which the hippocampus and dentate gyrus appear to rest (subiculum means a support), is a region of cortex transitional between six-layered neocortex and three-layered archicortex of the hippocampus. |
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http://www.columbia.edu/itc/hs/medical/neuralsci/2003/lab/Lab13_LimbicSystem/NAlab13_LimbicSystem.doc
(1924 words)
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| | Networks and Behaviour 2003 |
| | Compared to DG and hippocampal sub sectors CA1-CA4, information regarding the role of subiculum in spatial learning and memory process is considerably less. | | | Our previous studies have shown that subiculum is involved in spatial learning and memory functions. | | | Immediately following subicular lesion, the VSL + EE group was housed with 7-8 rats in a specially designed cage with a dimension of (104X65X104cm) and equipped with several exploratory objects like tunnels, toys etc. Following 10 days of postoperative recovery, rats were assessed for spatial task in an 8-arm radial maze. |
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http://www.ncbs.res.in/~events/nab2003/abstr_display.php?lname=D
(268 words)
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| | The Hippocampus |
| | Outputs from these structures can then affect many other areas of the brain. | | | The hippocampus is one of a group of structures forming the limbic system and is a part of the hippocampal formation, which also includes the dentate gyrus, subiculum, and entorhinal cortex. | | | Different components of the limbic system have been shown to play a critical role in all aspects of emotions, fear, learning and memory (Geinisman et al. |
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http://www.angelfire.com/yt/yas709neuroscience/hippocampus.htm
(1898 words)
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| | Steve M. Kim |
| | My research focuses on the dynamics of neural activity in hippocampal area CA1 and the subiculum during novel learning experience and subsequent memory consolidation. | | | The hippocampus and associated cortical regions subserve essential roles in the formation of new memories for places and events. | | | How do the coding properties of neurons in area CA1 and the subiculum change over the course of novel experience? |
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http://keck.ucsf.edu/~skim7
(425 words)
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| | [No title] |
| | S. O'Mara (Trinity College, Ireland) The subiculum: what it does, what it might do, and what we need to know | | | L. Menendez de la Prida (University of Madrid, Spain) Electrophysiological and morphological diversity of neurons from the rat subiculum in vitro: Synaptic Contributions to Focal and Widespread Spatiotemporal Dynamics in the Rat Subiculum | | | S. Deadwyler (Winston-Salem, USA) Differential but complementary mnemonic functions of the hippocampus and subiculum |
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http://www.ebbs2005.com/symposia.html
(1292 words)
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| | Down's syndrome - Medical Encyclopedia |
| | Neurofibrillary tangles and amyloid plaques are commonly found in both Down syndrome and Alzheimer's individuals. | | | Layer II of the entorhinal cortex and the subiculum, both critical for memory consolidation, are one of the first affected by the damage. | | | A gradual decrease in the number of nerve cells throughout the cortex follows. |
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http://www.nursingstudy.com/encyclopedia/Downs_syndrome.html
(698 words)
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| | Rosellinia: Evaluation of morphological characters 1 |
| | The colour of the subiculum may vary from light to dark purplish brow, rarely whitish, but this character is rarely diagnostic. | | | The subiculum in Rosellinia, that Læssøe and Spooner (1994) name "a false subiculum" on account of its situation around but not beneath the stromata, may be coarsely wolly or can bear synnemata | | | Remnants of subiculum are usually present around the stromatal base and visible when carefully checked. |
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http://pyrenomycetes.free.fr/rosellinia/keydir/morphchar.htm
(589 words)
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| | Rosellinia helvetica |
| | However, as this subiculum is less developped than in members of subgenus Rosellinia, and stromata smaller and less carbonaceous, it was kept in subgenus Calomastia (Petrini, 1993). | | | Two of our collections are unfortunately in poor condition and lack asci and fresh ascospores, therefore the ascospore slimy sheath was not checked. | | | The specimen JF-04250 is much more characteristic with its stromata deeply immersed in the subiculum and ascospores with a conspicuous slimy sheath. |
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http://pyrenomycetes.free.fr/rosellinia/html/Rosellinia_helvetica.htm
(298 words)
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| | APStracts 5:096N, 1998 |
| | Gamma oscillations were evoked in the subiculum in rat transverse hippocampal slices by tetanic stimulation (200ms/100Hz) of either CA1 or subiculum. | | | The present study addresses the origin of this more complex form of gamma oscillation in the subiculum. | | | Oscillating sequences of EPSPs and intrinsic and/or synaptic hyperpolarizing potentials in IB subicular neurons generate gamma frequency spike doublets, which depend on both the intrinsic properties of these neurons and their temporally patterned synaptic input. |
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http://www.uth.tmc.edu/apstracts/1998/jn/March/096N.html
(417 words)
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| | [No title] |
| | Hypocreales: ascus unitunicate, inamyloid; stroma or subiculum present; perithecia are light colored |
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http://www.humboldt.edu/~dll2/bot359/htmfiles/pyreno/hypomy1.htm
(38 words)
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| | CRISP - Computer Retrieval of Information on Scientific Projects, Abstract Display |
| | The greater complexity and location of subiculum makes it a logical next structure for study of additional mechanisms of seizure origin and spread. | | | Abstract: DESCRIPTION (provided by applicant): The subiculum is a crossroads of hippocampal and parahippocampal projections, and the major output structure of the region. | | | This will set the stage for use of the subiculum slice and subiculum computer model as an epilepsy model. |
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http://crisp.cit.nih.gov/crisp/CRISP_LIB.getdoc?textkey=6820651&p_grant_num=1R01NS045612-01A2&p_query=&ticket=10457645&p_audit_session_id=48427889&p_keywords=
(306 words)
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| | Topographic projections from the subiculum to the limbic regions of the medial frontal cortex in the cat. |
| | Topographic projections from the subiculum to the limbic regions of the medial frontal cortex in the cat. | | | The projections were topographically organized: the temporal-septal shift along the long axis of the subiculum of the Hv corresponded to a rostroventral-caudodorsal shift in the anterogradely labeled limbic regions of the medial frontal cortex. | | | The cells of origin of these projections were then confirmed to be pyramidal neurons in the subiculum of the Hv. |
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http://brainmeta.com/neuroanat/a37.html
(177 words)
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| | ICP monitors |
| | The pathway linking the hippocampal formation with the basal forebrain and brain stem. | | | From the subiculum some axons return into the entorhinal cortex and others traverse the alveus to enter the fornix via the fimbria. | | | Diagonal band fiber components from the medial septal nucleus enter the hippocampus via the fibria of the fornix and distributed diffusely. |
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http://www.ucsf.edu/nreview/02.1-Anatomy-Brain&SC/LimbicSystem.html
(1295 words)
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| | [No title] |
| | Efferent fibers project to the entire hippocampal formation, the habenula, hypothalamus, thalamus, amygdala, mamillary bodies and the cerebral cortex. | | | The subcallosal area includes a cluster of small septal nuclei that lie immediately anterior to the paraterminal gyrus and anterior commissure. | | | The septal nuclei receive input from multiple midbrain nuclei, the substantia nigra, the CA1 region of the cornu ammonis, the subiculum, amygdala, lateral hypothalamus, cingulate gyrus, and mamillary bodies. |
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http://spinwarp.ucsd.edu/NeuroWeb/Text/br-800epi.htm
(2797 words)
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| | Memory Research Lab at UCSD Larry Squire |
| | Clark, R.E., Broadbent, N.J., Zola, S.M., and Squire, L.R. Anterograde amnesia and temporally-graded retrograde amnesia for a nonspatial memory task following lesions of hippocampus and subiculum. |
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http://whoville.ucsd.edu/2000.htm
(1831 words)
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| | iLab Publications - University of Southern California |
| | We demonstrate a positive-going deflection in the evoked synaptic response in area CA1 following stimulation in dorsal subiculum. | | | The substantial forward projection from hippocampal area CA1 to the subiculum has been comprehensively described, both anatomically and neurophysiologically. | | | There are few data, however, regarding the existence of a backward projection from the subiculum to area CA1. |
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http://ilab.usc.edu/jtrack/28/Commins_etal02.html
(136 words)
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| | APStracts 6:0531N, 1999. |
| | We conclude that Y5 receptors appear to regulate excitability to some degree in the subiculum of young rats but their contribution is relatively small compared with those of Y2 receptors, declines with age, and is insufficient to block or significantly attenuate STIB-induced afterdischarges. | | | We recorded initially from area CA1 pyramidal cells, but subsequently switched to cells from the subiculum, where a much greater frequency of response was observed to Y5 agonist application. | | | Y5 receptor-mediated synaptic inhibition was more frequently observed in slices from younger animals, while the nonselective agonist appeared equally effective at all ages tested. |
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http://www.uth.tmc.edu/apstracts/1999/jn/December/531n.html
(472 words)
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| | Ontogeny of oxytocin receptors in rat forebrain: a quantitative study. |
| | In contrast to these evanescent developmental sites, oxytocin receptors in the bed nucleus of the stria terminalis and the ventromedial nucleus of the hypothalamus only appeared in adulthood, presumably in response to the surge of gonadal steroids at puberty. | | | Competition studies on coronal sections through posterior cingulate, septum, and dorsal subiculum at P10 demonstrated that transient binding sites in these areas were indeed oxytocin selective (OXY greater than AVP greater tha V1 greater than V2). | | | With in vitro receptor autoradiography, binding wa noted on the first postnatal day in dorsal subiculum and thalamus. |
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http://www.arclab.org/medlineupdates/abstract_2558421.html
(217 words)
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| | Entorhinal cortex of the monkey: V. Projections to the dentate gyrus, hippocampus, and subicular complex. |
| | The entorhinal projection to the CA1 field of the hippocampus and to the subiculum followed a transverse rather than radial gradient of distribution. | | | Injections of the retrograde tracers Fast blue, Diamidino yellow, and wheat germ agglutinin-horseradish peroxidase (WGA-HRP) were also placed into the dentate gyrus, hippocampus, and subicular complex, and the distribution of retrogradely labeled cells in the entorhinal cortex was plotted using a computer-aided digitizing system. | | | More caudal levels of the entorhinal cortex projected to progressively more distal portions of the subiculum (towards the presubiculum) and more proximal portions of CA1 (towards CA2). |
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http://brainmeta.com/neuroanat/a104.html
(264 words)
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| | Data from CBS Aphyllophorales database |
| | In addition, C. magnahypha possesses subiculum hyphae that are broader, much thinner walled, and with paler crystals. | | | Finally, the ellipsoid basidiospores distinguish C. magnahypha from other Candelabrochaete species. | | | Habitat: On well-decayed hardwood; apparently associated with a white rot. |
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http://www.cbs.knaw.nl/scripts/Aphyllophorales.dll/ShowName?Nr=64543
(138 words)
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