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| | OhioLINK ETD: THULLEN, TIMOTHY |
 | | The first was the adoptive transfer of immune donor splenocytes sensitized to the Pneumocystis antigen, major surface glycoprotein, to corticosteroid- treated rats with Pneumocystis pneumonia. | | | The second approach to study host defenses was the development of a CD4- depleted rat model of Pneumocystis pneumonia. | | | Two approaches were made to study host defense to Pneumocystis in the rat model. |
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http://www.ohiolink.edu/etd/view.cgi?ucin1066676759
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| | SECRETION FROM NEUROPEPTIDE-TREATED SPLENOCYTES MODIFIES OVARIAN STEROIDOGENESIS |
| | When splenocytes from SON-t rats were treated with VIP or NPY, their secretions increased the progesterone release from the ovaries (p< 0.001), compared with the secretions from SON-t rats untreated splenocytes. | | | SON transection in adult rats affects splenocyte secretions, which participate in the ovarian steroidogenic response, particularly in progesterone release, which secretions might be controlled by adrenergic influences since the number of splenocyte b-adrenergic receptors changes through SON-coeliac ganglion-noradrenergic postganglionic innervation of the spleen20. | | | When culture medium of splenocytes from SON-t rats was used, the androstenedione release from ovaries did not change in relation to that observed when the splenocyte culture medium derived from control rats. |
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http://www.medicinabuenosaires.com/vol61-01/1/secretion.htm
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| | Mechanical ventilation of healthy rats suppresses peripheral immune function -- Vreugdenhil et al. 23 (1): 122 -- ... |
| | Splenocytes from low peak inspiratory pressure (PIP)/PEEP, high PIP/PEEP or high PIP/zero PEEP (ZEEP)-ventilated rats were stimulated with phytohaemagglutinin. | | | The effect of hypoxia was determined in the hypoxic positive end-expiratory pressure (PEEP) group. | | | Splenocytes from low peak inspiratory pressure (PIP)/PEEP, high PIP/PEEP or high PIP/zero PEEP (ZEEP)-ventilated rats were stimulated in vitro with phytohaemagglutinin (200 µg·mL |
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http://erj.ersjournals.com/cgi/content/full/23/1/122
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| | APStracts 5:0276C, 1998. |
| | To study this, male rats underwent sham operation or laparotomy and were bled to and maintained at a mean arterial blood pressure of 40_mmHg until 40% of the maximum shed blood volume (MBV) was returned in the form of Ringer_s lactate (RL). | | | Therefore, provision of L-arginine, the substrate for cNOS, during resuscitation following trauma-hemorrhage should be considered as a novel and safe approach for improving splenic organ blood flow and the depressed splenocyte functions under such conditions. | | | The results indicate that administration of L-arginine improved the depressed splenic blood flow and restored the depressed splenocyte functions following trauma-hemorrhage. |
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http://www.uth.tmc.edu/apstracts/1998/cell/October/276C.html
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| | INTERFERON-GAMMA (IFN_) IS REQUIRED FOR LONGTERM ALLOGRAFT SURVIVAL INDUCED BY COMBINED ADMINISTRATION OF ... |
| | Conclusions: (1) Endogenous IFN_ does not hinder but rather facilitates induction of longterm allograft survival in mice treated with donor-specific splenocyte transfusion and CTLA4Ig. | | | Because IFN_ has important immunoregulatory functions, we addressed whether this cytokine plays a role in DSST+CTLA4Ig- mediated immunosuppression by comparing the survival of fully allogeneic cardiac or skin grafts in wildtype (IFN_ | | | Administration of donor splenocytes or bone marrow enhances the salutary effect of B7-CD28 costimulation blockade on allograft survival in rodents. |
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http://www.a-s-t.org/abstracts98/abs433.htm
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| | [No title] |
| | The ability of rbPRL to induce splenocyte proliferation was examined in the next experiment. | | | The influence of rbPRL, natural ovine PRL (noPRL) and rmPRL on splenocyte proliferation. | | | The ability of rbPRL to induce the proliferation of mouse splenocytes has also been reported by others using a natural rPRL preparation and rat splenocytes (23,24). |
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http://www.med.wayne.edu/physiology/facultyprofile/gala/PUB.HTM
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| | Immunomodulatory and protective effects of N-acetylcysteine in mitogen-activated murine splenocytes in vitro. |
| | The dose-response relationship describing the effects of NAC on lymphocyte proliferation with Con A-induced responses were enhanced in a dose-dependent manner, whereas the corresponding LPS-induced responses increased to a maximum level followed by decline in responses at higher concentrations of NAC. | | | N-Acetylcysteine (NAC) is a pro-glutathione drug used to treat chronic lung disorders and because of its anti-AIDS virus activity in vitro, has been proposed for AIDS therapy. | | | The state of the art may have changed since the publication date. |
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http://www.aegis.com/aidsline/1997/may/M9751344.html
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| | ASTP Abstract kto002.htm |
| | Thus, the tolerant splenocytes lost the ability to mediate acute rejection. | | | These observations support the hypothesis that allograft tolerance in this experimental model is an active process driven by graft alloantigens that can interfere in some general way with local acute rejection responses. | | | This demonstrated that the tolerant splenocytes could interfere with the acute rejection of cardiac allografts, even if they displayed new MHC molecules, provided that they also displayed some of the original tolerizing MHC molecules. |
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http://www.a-s-t.org/abstracts/kto002.htm
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| | IngentaConnect Inhibition of Rat Splenocyte Proliferation with Methylprednisolon... |
| | Inhibition of Rat Splenocyte Proliferation with Methylprednisolone: In Vivo Effect of Liposomal Formulation | | | IngentaConnect Inhibition of Rat Splenocyte Proliferation with Methylprednisolon... | | | In vivo studies in rats utilized 2 mg/kg IV bolus doses of liposomal MPL compared to drug in solution. |
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http://www.ingentaconnect.com/content/klu/pham/1994/00000011/00000006/00304541
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| | ELISPOT - Wikipedia, the free encyclopedia |
| | The ELISPOT method is most often used to determine the amount (i.e. | | | An animated depiction of the cytokine ELISPOT assay process | | | the concentration) of activated antigen-specific cytotoxic T-cells in a given sample of splenocytes harvested from immunized animals, usually mice. |
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http://en.wikipedia.org/wiki/ELISPOT
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| | Jahrbuch-CD der MPG 2003 - Increased splenocyte proliferat |
| | We used beta-endorphin-deficient mice as a novel approach to confirm the physiological role that opioid peptides play in the development or regulation of the immune system. | | | Increased splenocyte proliferative response and cytokine production in beta-endorphin-deficient mice | | | We found that mice lacking beta-endorphin possessed an enhanced immune response, measured in terms of splenocyte proliferation and interleukin (IL)-2 mRNA levels, in vitro production of the splenic macrophage inflammatory cytokines IL-6 and Tumor Necrosis Factor (TNF)-alpha and plasma IL-6 following lipopolysaccharide (LPS) administration. |
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http://www.mpg.de/forschungsergebnisse/wissVeroeffentlichungen/archivListenJahrbuch/2002/23/publZIM47.html
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| | Characterization of Viral Inhibitory Substance Released from Fused Splenocyte |
| | Characterization of Viral Inhibitory Substance Released from Fused Splenocyte | | | Mice were infected with EMC-B and their splenocytes were fused with myeloma cells. | | | The prevention and treatment effect of VIS on EMC-D infection in SJL/J mice might be due to the inhibition of the virus replication by VIS. |
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http://bric.postech.ac.kr/publications/mc/mc072/m07203.html
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| | Spleen and thymus cell subsets modified by long-term morphine administration and murine AIDS--II. |
| | Moreover, under the experimental conditions of protein-malnutrition and morphine treatment potentiation of immune dysfunction by murine retrovirus infection was investigated. | | | Retrovirus infection-induced splenocyte proliferation was partially regulated by morphine treatment. | | | Thus morphine altered the immune system by down-regulating splenocyte proliferation, because retrovirus infection-induced splenocyte proliferation was partially regulated by morphine treatment. |
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http://www.aegis.com/aidsline/1994/mar/M9430659.html
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| | ASGSB 1998 - EFFECTIVENESS OF GROUND BASED MODELS FOR SPACEFLIGHT IN SPLENOCYTE SUBPOPULATIONS |
| | There were no consistent changes in these treatment groups in the cell populations observed. | | | This finding supports the hypothesis that there are stressors unique to the spaceflight environment that can not be fully modeled on the ground. | | | Splenocytes were labeled with antibodies against CD4, CD8, CD11b, and TCR and analyzed by flow cytometry. |
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http://www.lifesci.indstate.edu/asgsb/programs/1998/20.html
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| | Proceedings of the Oklahoma Academy of Science |
| | Increased desires among physiological ecologists to understand interrelationships among immunocompetence, environment, and demography in wild populations (1) has necessitated the development of baseline immunological techniques applicable to wild animal species. | | | Phenotypic and Functional Characterization of Cotton Rat (Sigmodon hispidus) Splenocytes Separated on Nylon Wool | | | Although HP is primarily a T-cell and natural killer cell (non-T, non-B cells) surface marker in cows (15), laboratory mice (8, 16), and laboratory rats (17), we observed no difference in relative abundance of HP+ cells among cell subpopulations in the cotton rat. |
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http://digital.library.okstate.edu/oas/oas_htm_files/v75/p31_37.html
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| | [No title] |
| | Splenocytes and peritoneal macrophages were harvested in the acute phase of EAE and in remission, and from controls. | | | To analyze the effects in vitro of alpha- and beta-adrenoceptor agonists on splenocyte proliferation and on proinflammatory cytokine production in splenocytes and peritoneal macrophages (MF) in different stages of EAE. | | | EAE acute phase and remission animals showed reduced terbutaline-induced inhibition of IFN-gamma production. |
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http://www.mult-sclerosis.org/news/Dec2003/MedlineAdrenergicModulationofCellularImmuneFunctionsinEAE.html
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| | Untitled Document |
| | This study shows that short-term aflatoxin ingestion by wild turkeys can induce undesirable physiologic changes; therefore, exposure of wild turkeys to feeds containing aflatoxin levels of 100 micrograms aflatoxin/kg feed or more should be avoided. | | | Each splenocyte preparation was administered intravenously to one of three recipient groups consisting of 10 BSW turkeys each. | | | No studies evaluating the efficacy of transfer of immunity in preventing aspergillosis in birds have been reported. |
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http://www.aspergillus.man.ac.uk/secure/veterinary/listings.php?family=Meleagrididae
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| | Figures |
| | Splenocytes were obtained from three mice, counted and then pooled for flow cytometric analysis; numbers indicated are per spleen. | | | (a,b) RANKL and TNF-α concentrations measured in supernatant of anti-CD3 antibody-stimulated splenocytes. | | | Splenocyte suspensions of three mice within each group were pooled and lysed. |
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http://www.medscape.com/content/2004/00/47/26/472604/472604_fig.html
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| | Figure - Nature Genetics |
| | The 100% value corresponds to the 0-h time point for acetylated H3-Lys9 and methylated H3-Lys4 and to the splenocyte value for methylated H3-Lys9. | | | The 24-h values correspond to the relative values observed in resting splenocytes, which corresponds to lymphocytes in which Dntt had been silent for a long period of time. | | | The 24-h values correspond to the relative values observed in resting splenocytes. |
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http://www.nature.com/ng/journal/v36/n5/fig_tab/ng1351_F3.html
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