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Topic: Somatic cell


  
 bioethics.net :: RETRACTED: Oocyte and Somatic Cell Procurement for Stem Cell Research:
This “cell donation counselor” could work to ensure that the patient is not operating under a therapeutic misconception.
The researcher emphasized that the cell donor would not receive any intellectual or property rights that might be derived from the study, and that future therapeutic applications of the study could not be guaranteed.
We acknowledge that the consent procedures for oocyte and somatic cell donation here described are works in progress; we believe these two procedures could be improved in various ways, although each proposed change raises new practical considerations.
http://www.bioethics.net/journal/j_articles.php?aid=878   (2578 words)

  
 Somatic Cell Fusion during Sounding Rocket Flight
No differences were apparent between the cells that were fused immediately at the start of µg and those fused at the end of µg.
These cells were compared with 1 g reference experiments simultaneously fused and fixed at the ground site.
Confluent monolayers of primary human skin fibroblasts, grown on coverslips, were mounted between two electrodes and fused by discharging a capacitor in a low- conductive medium.
http://esapub.esrin.esa.it/sp/sp1206/jongk.htm   (1807 words)

  
 Guidance for Industry: Guidance for Human Somatic Cell Therapy and Gene Therapy
As new classes of gene therapies and somatic cell therapies are developed, concerns and methods of testing will most likely change.
The desired function should be monitored when the cells are subjected to manipulation, and the tests carried out periodically to assure that the desired trait is retained.
Cells for therapeutic purposes may be delivered in various ways.
http://www.fda.gov/cber/gdlns/somgene.htm   (9257 words)

  
 Somatic cell - Wikipedia, the free encyclopedia
This means that when an ova and sperm fuse, they produce a zygote with 23 pairs of chromosomes
In practice, this technique has so far been problematic, although there have been a few high profile successes, such as Dolly the Sheep and, more recently, Snuppy, the first cloned dog.
A somatic cell is generally taken to mean any cell forming the body of an organism: the word "somatic" is derived from the Greek word sōma, meaning "body".
http://en.wikipedia.org/wiki/Somatic_cell   (564 words)

  
 Glossary [Stem Cell Information]
Cord blood is currently used to treat patients who have undergone chemotherapy to destroy their bone marrow due to cancer or other blood-related disorders.
Trophoblast—The extraembryonic tissue responsible for implantation, developing into the placenta, and controlling the exchange of oxygen and metabolites between mother and embryo.
DNA carries the instructions or blueprint for making all the structures and materials the body needs to function.
http://stemcells.nih.gov/info/glossary.asp   (1825 words)

  
 Biological Basis of Heredity: Cell Reproduction
Virtually all (99.9%) sex cells in a woman's ovaries never develop beyond the primary oöcyte stage and eventually are reabsorbed by her body.
Ejaculating large numbers of sperm at the same time is nature's way of overcoming these difficulties and increasing the likelihood that conception will take place.
, or body cells, such as those that make up skin, hair, and muscle, are duplicated by
http://anthro.palomar.edu/biobasis/bio_2.htm   (1991 words)

  
 Somatic Cell Nuclear Transfer
Because SCNT involves cloning, there are many ethical concerns in using this technique in humans.
For this reason, experiments of this nature have only been conducted in mice.
Somatic Cell Nuclear Transfer (SCNT), also called therapeutic cloning, is the process by which a somatic cell is fused with a enucleated oocyte.
http://www.molbio.princeton.edu/courses/mb427/2001/projects/09/transfer.htm   (181 words)

  
 Nanos suppresses somatic cell fate in Drosophila germ line -- Hayashi et al. 101 (28): 10338 -- Proceedings of the ...
shape and were neither associated with nor embedded within somatic
Nos is required to repress the pathway leading
Thus, we conclude that Nos is essential for germ-line/soma
http://www.pnas.org/cgi/content/full/101/28/10338   (2863 words)

  
 What is Cloning?
Artificial embryo twinning uses the same approach, but it occurs in a Petri dish instead of in the mother's body.
How does SCNT differ from the natural way of making an embryo?
Nuclear: The nucleus is like the cell's brain.
http://gslc.genetics.utah.edu/units/cloning/whatiscloning   (863 words)

  
 somatic cell
Each embryo that she advocates experimenting on, whether created using the somatic cell nuclear transfer technique or not, could be in the newborn stage of...
...to treatment with anticancer drugs can also result from a variety of factors including individual variations in patients and somatic cell genetic differences...
Could the CURE for all diseases be BANNED?
http://www.mongabay.com/igapo/biotech/somatic_cell.html   (3059 words)

  
 ScienceWeek
This technique is associated with important gestational losses in early pregnancy during the first two to three months and in the late fetal and perinatal periods in cows.
One obstacle to therapeutic applications is obtaining stem cells for a given patient.
A nucleus that was once part of an intestine, skin, or muscle cell is therefore transformed into that of an embryonic cell.
http://scienceweek.com/2003/sw030314.htm   (11178 words)

  
 DHI Somatic Cell Count Program Guidelines
Correlation of antibiotic therapy success during lactation with antimicrobial susceptibility test results for bovine mastitis.
Factors associated with bacteriological cure during lactation after therapy for subclinical mastitis caused by Staphylococcus aureus.
Effectiveness of intramammary antibiotic therapy based on somatic cell count.
http://www.ext.vt.edu/pubs/dairy/404-228/404-228.html   (3209 words)

  
 Reprogramming complicates stem cell debate - Stem Cell Research - MSNBC.com
Technique could revolutionize therapies; what role will politics play?
Stem cells are the master cells that replenish all the body's tissues, from skin and blood to the brain and heart.
Scientists are working to develop new techniques that may one day allow the body to produce fresh cells to heal itself. 
http://www.msnbc.msn.com/id/8805408   (873 words)

  
 BAA NHLBI-HB-03-06, Somatic Cell Therapy Processing Facilities
Statement of Work, paragraph a., first sentence, currently reads "The project is designed to develop novel somatic cellular therapies that will aid investigators by providing support in areas ranging from basic science through animal studies to proof-of-principle and eventually human trials." The term "investigators" is hereby interpreted to mean any investigator requesting support.
Additional Somatic Cell Processing Facility Project Requirements, item 1., is clarified as follows: The cost information associated with the examples of previous clinical grade biological products shall be included in the cost proposal; however, costs shall not be included as a line item in the total 5-year project cost.
Phase II—54 months (April 1, 2004—September 29, 2008): development of somatic cellular therapies"
http://www.nhlbi.nih.gov/funding/inits/archive/hb03-06a1.htm   (426 words)

  
 somatic cell > Cell Phone Everything
We'd like you to first establish a link to our site.
Somatic Cell Nuclear Transfer (SCNT) or therapeutic cloning involves removing the nucleus of an unfertilized...
This NebGuide describes what somatic cells are, and their significance related to mastitis and milk quality.
http://www.studygrp.com/somatic-cell   (279 words)

  
 somatic cell - definition of somatic cell in Encyclopedia
A somatic cell is a type of cell in an organism, such as the human body.
The cells in the germline are cells such as the gametes (sperm or ovum,) cells that produce the gametes (such as gametocytes), and event the zygote, because it leads to the production of the gametes.
Gametes, in contrast, have only 23 chromosomes, making them haploid cells.
http://encyclopedia.laborlawtalk.com/somatic_cell   (216 words)

  
 somatic cell - definition of somatic cell by the Free Online Dictionary, Thesaurus and Encyclopedia.
muscle cell, muscle fiber, muscle fibre - an elongated contractile cell that forms the muscles of the body
skin cell - any of the cells making up the skin
cell - (biology) the basic structural and functional unit of all organisms; cells may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
http://www.thefreedictionary.com/somatic%20cell   (400 words)

  
 Somatic cell nuclear transfer - Wikipedia, the free encyclopedia
This technique is currently the basis for cloning animals, such as the famous Dolly the sheep, and could theoretically be used to clone humans.
In genetics, somatic cell nuclear transfer (SCNT) is a technique for cloning.
The nucleus of a cell contains DNA, which acts roughly as its blueprint (although unlike an actual blueprint, these instructions are greatly affected by environment as well as other factors not yet fully understood and can change over time).
http://en.wikipedia.org/wiki/Somatic_cell_nuclear_transfer   (343 words)

  
 ISSCR :: Glossary : Glossary
A specific subset of cells within the body, defined by their appearance, location and function.
Implanted embryos in the early stages of development until the establishment of the body plan of a developed organism with identifiable tissues and organs.
However, in human medicine, this technique can be used to isolate embryonic stem cells from eggs that have undergone nuclear transfer.
http://www.isscr.org/glossary   (2890 words)

  
 Somatic Cell Counts
The white blood cell portion of the SCC represents the phagocytes, and other similar cells, that are released by the inflammation process in response to an invading organism or a mechanical stress.
This is, of course, a claim we cannot make, but it is a fun fact for inquiring minds.
While the SCC is not diagnostic for the presence or absence of mastitis, it is true that a clinical case of mastitis that might cause an individual cow’s SCC to go over 5 million may affect the bulk tank reading and serve as a red flag for the producer.
http://www.diamondv.com/protected03/articles/dairy/somatic_cell_counts.htm   (414 words)

  
 Genome article - Genome biology organism sequence chromosomes diploid somatic cell sexually - What-Means.com
Genomes are more than the sum of an organism's genes and have traits that may be measured and studied without reference to the details of any particular genes and their products.
Also, eukaryotic cells seem to have experienced a transfer of some genetic material from their chloroplast and mitochondrial genomes to their nuclear chromosomes.
Horizontal gene transfer seems to be common among many microbes.
http://www.what-means.com/encyclopedia/Genome   (730 words)

  
 Germline vs. Soma
Mutations that occur in a somatic cell, in the bone marrow or liver for example, may
The fusion of one sperm cell and one egg cell represents the only genetic link between the bodies of parents and the body of their child and
At each generation, the embryo that develops from the zygote not only sets aside some germplasm for the next generation but also produces the cells that will develop into the body, the soma, of the organism.
http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/G/GermlineVsSoma.html   (1453 words)

  
 Genomic Analysis
The virus facilitates the fusing of the two cell types to form a hybrid cell.
Because the human and mouse chromosomes can be distinguished by chromosome staining techniques, it can be determined which human cells are retained with a specific cell line.
Individual human chromosomes can be selected by a technique called flourescence-activated chromosome sorting.
http://www.ndsu.nodak.edu/instruct/mcclean/plsc431/genomic/genomic3.htm   (566 words)

  
 Somatic Hybridization
Cultured cells from two different species can be induced to fuse to form hybrid cells whose nuclei also fuse (heterokaryons).
The cell lines were tested by enzyme electrophoresis for their ability to make the human hypoxanthine phosphoribosyl transferase (HPRT), glucose-6-phosphate dehydrogenase (G6PD) and thymidine kinase (TK).
When mouse-human hybrid cells are cultured they loose many of the human chromosomes.
http://opbs.okstate.edu/~melcher/MG/MGW1/MG1213.html   (258 words)

  
 Somatic Cell Count Benchmarks
The epithelial cells originate from udder secretory tissue and increase as a result of injury or infection.
Since both types of cells originate from within the cow's body, they are given the name somatic or body cells.
Somatic cell count measurements including SCCS and WTSCC provide the opportunity to monitor and evaluate udder health.
http://pubs.caes.uga.edu/caespubs/pubcd/B1194.htm   (1627 words)

  
 Somatic Cell Nuclear Transfer
technique, stem cells that are genetically identical with the cells of a recipient's own body could be derived.
The nucleus of the egg (containing its DNA) is removed and replaced with the nucleus (and its DNA) of a somatic cell (such as skin or blood) from the recipient.
The resulting stem cells would be immunologically compatible with the recipient's own tissues because they would not contain DNA that produces proteins that the recipient's body would react to as "foreign".
http://www4.nationalacademies.org/onpi/webextra.nsf/0/1d132e9457bebd7085256ac300052b2b?OpenDocument   (147 words)

  
 somatic cell
one of the cells that take part in the formation of the body, becoming differentiated into the various tissues, organs, etc.
http://www.infoplease.com/dictionary/somatic+cell   (38 words)

  
 Genetics / Somatic cell hybrids
Hi all, I try to analyze my cell cycle data with flowjo.
The mammalian cell cultures are usually performed in 5% CO2 incubator.
This full text book section is from NCBI books series.
http://biowww.net/browse-67.html   (137 words)

  
 Wordsmyth
any of an organism's cells that contribute to the formation of the body, being differentiated into the various tissues and organs, except for germ cells.
If you register now this message and color will disappear, and ensure that you won't miss any of the unique Wordsmyth features you've come to enjoy.
http://wordsmyth.net/live/home.php?script=search&matchent=somatic+cell&...   (93 words)

  
 Somatic Cell Hybrid Panel
The somatic cell hybrid panel developed by Yerle et al.
Diagrams representing the presence of porcine chromosomes and fragments in each hybrid clones and all available data of regional assignment obtained on this hybrid panel :
http://www.toulouse.inra.fr/lgc/pig/hybrid.htm   (170 words)

  
 somatic cell : Definition
A cell that is not destined to become a gamete; a cell whose genes cannot be passed on to future generations.
Search for somatic cell in these other databases too
http://www.everythingbio.com/glos/definition.php?ID=2524   (121 words)

  
 CLOMID EFFECTS ON TRISOMY 18
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http://clomid-effects-on-trisomy-18.medicationhelp.net   (395 words)

  
 somatic Cell Count
Herds with a very low SCC will see less benefit.
Bulk Milk Cell Count) the higher the potential benefit.
ADHIS will implement an ABV for Somatic Cell Count (SCC) in February 2002.
http://www.dairyconsult.com/somatic_cell_counts.htm   (711 words)

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