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Sildenafil joins bosentan and prostacyclin, both of which are given by continuous infusion, as therapies for this condition.
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Sildenafil citrate increases the body's ability to achieve and maintain erection during sexual stimulation.
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Sildenafil (Viagra&;) is used to treat erectile dysfunction (impotence) in men.  It can help many men who have erectile dysfunction to keep an erection upon sexual excitement (stimulation).  Taking sildenafil will not automatically cause an erection.&; Men who take it must be sexually stimulated for an effect to occur.
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Sildenafil acts as a selective inhibitor of cyclic GMP-specific phosphodiesterase type 5, resulting in smooth muscle relaxation, vasodilation, and enhanced penile erection.
If patients are taking a combination of antihypertensive medications, they should be cautioned about the possibility of sildenafil-induced hypotension.
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This relaxation may be mediated by nitric oxide via cyclic guanosine monophosphate (cGMP).
Dose-response relationships were shown for erection frequency, rigidity, duration, number of satisfactory intercourses and quality of sex life.
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Sildenafil is used to treat men with erectile dysfunction (also called sexual impotence) because it helps to maintain an erection that is produced when the penis is stroked.
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Priapism (history of)—Although sildenafil does not cause priapism (erection lasting longer than 6 hours), patients with these conditions have an increased risk of priapism and it could occur while using sildenafil
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Sildenafil Citrate (the generic name for Caverta and all Viagra products) is is by far the most widely prescribed medication for treatment of male sexual function problems (erection problems).
Unlike Generic Drugs, a large part of the costs incurred by original manufacturers of brand name drugs are for research and development and advertising.
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If you use sildenafil and get chest pains, be sure to tell the paramedics, nurses or doctors at the hospital that you use it and how long ago it was that you last took a tablet.
Even if you take sildenafil, you still need physical and mental stimulation and desire to have an erection.
Erectile dysfunction is the inability of the penis to become rigid (hard), or to stay rigid long enough to finish having sex.
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In each of the studies significant (p<0.0001) improvements were apparent with sildenafil treatment compared to placebo in relation to frequency of penetration and maintenance of erection after penetration.
The treatment options available to manage ED include psychosexual counselling, hormonal therapy (for those with hypogonadism), prosthetic penile implants, vacuum devices, vascular surgery, and intracavernosal injection or transurethral therapy with vasodilators.
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Upon follow-up, the patient described that she experienced increased sensations of warmth, lubrication, and tingling in the genital area, lasting several hours and resulting in greatly increased sensitivity and a pleasurable sexual response.
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Carcinogenicity Review of Sildenafil in Rats and Mice
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From the marketing of sildenafil citrate (Viagra) in late March through mid-November 1998, during which more than 6 million outpatient prescriptions (representing about 50 million tablets) were dispensed, the FDA received reports of 130 U.S. patients who died after having been prescribed this drug.
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Excluded were reports of 55 foreign patients, 35 with unverifiable information (from hearsay, rumor, the media, or unidentifiable reporters), and 22 with unconfirmed Viagra use.
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