|
| |
| | Medical Encyclopedia: Serum sickness (Print Version) |
 | | People who have experienced serum sickness, anaphylactic shock, or drug allergy should avoid future use of the antiserum or drug. | | | Unlike other drug allergies, which occur very soon after receiving the medication for the second (or subsequent) time, serum sickness can develop 7 to 21 days after the first exposure to a medication. | | | There is no known way to prevent the development of serum sickness. |
|
http://www.nlm.nih.gov/medlineplus/print/ency/article/000820.htm
|
|
| |
| | Serum Sickness - Talk Medical |
| | There is no way to prevent serum sickness. | | | A person with serum sickness usually recovers completely within a week. | | | This will help prevent serum sickness from happening again. |
|
http://www.talkmedical.com/diseases-disorders/866/Serum-Sickness
|
|
| |
| | eMedicine - Serum Sickness : Article by Lawrence K Jung, MD |
| | Inform patients and their families that serum sickness is a complication of therapeutic use of heterologous serum. | | | Bielory L, Gascon P, Lawley TJ: Human serum sickness: a prospective analysis of 35 patients treated with equine anti-thymocyte globulin for bone marrow failure. | | | Incidence of this syndrome with medications usually is very low; thus, overall incidence of serum sickness has decreased. |
|
http://emedicine.com/PED/topic2082.htm
|
|
| |
| | Serum sickness |
| | The most effective method of prevention is simple avoidance of antitoxins that may cause serum sickness. | | | Antihistamines, pain relievers, and corticosteroids may be given to relieve the symptoms. | | | These may include changes in vision, and difficulty in movement. |
|
http://www.healthatoz.com/healthatoz/Atoz/ency/serum_sickness.jsp
|
|
| |
| | BBC News HEALTH Sleeping sickness test 'promising' |
| | SRA was present in all 29 samples from patients with sleeping sickness and in all eight cattle samples that were resistant to human serum in vitro. | | | Sleeping sickness is almost always fatal, although drugs are used to treat the disease. | | | Livestock there are hosts to two sleeping sickness parasites - Trypanosoma brucei rhodesiense, which affects humans, and Trypanosoma brucei brucei, which is non-human-infective. |
|
http://news.bbc.co.uk/1/low/health/1708646.stm
|
|
| |
| | AJC Health : Integrative Medicine : Conditions : Serum Sickness ajc.com |
| | Scientific studies have not yet evaluated the effectiveness of CAM therapies in treating serum sickness. | | | To date, no scientific studies have investigated the value of homeopathic remedies in treating serum sickness. | | | Doctors will typically prescribe antihistamines or analgesics for serum sickness. |
|
http://www.ajc.com/health/altmed/shared/health/alt_medicine/ConsConditions/SerumSicknesscc.html
|
|
| |
| | Treatment |
| | The dynamic nature of circulating immune complexes, their complexity, their rapidly changing equilibrium patterns and their pathogenicity must be appreciated before the clinician can properly interpret the patterns of illness his patients describe. | | | The dynamic nature of circulating immune complexes, their complexity, their rapidly changing exquilibrum patterns aaand their pathogenicity must be appreciated before the clinican can properly interpret the patterns of illnes his patients’ describe. | | | Inhabitants in "sick house syndrome" (SHS) homes suffer from allergy, asthma, sinus and other respiratory problems, including hypersensitivity pneumonitis and aspergillosis. |
|
http://www.mold-survivor.com/treatment.htm
|
|
| |
| | eMedicine - Serum Sickness : Article by Hassan M Alissa, MD |
| | The pathological hallmark in the skin is a leukocytoclastic vasculitis. | | | This or other oral forms of corticosteroids (eg, prednisolone) are useful in managing mild-to-moderate serum sickness treated in an outpatient setting. | | | Internationally: Serum sickness occurs worldwide, in proportion to the therapeutic use of foreign antigens and drugs. |
|
http://www.emedicine.com/med/topic2105.htm
|
|
| |
| | Re: 1 dose of levaquin |
| | Serums Sickness usually develops within 7 to 21 days after taking the medication. | | | But if someone has taken the drug before, the response can be immediate. | | | This went along with joint pain, > paresthsia, achilles tendon pain, muscled > twitching, etc. > The rash is the key. |
|
http://www.rxlist.com/rxboard/levaquin.pl?read=1069
|
|
| |
| | WHO Other rabies biological products |
| | In 1965, approximately 16% of persons treated with antirabies serum of equine origin were reported to have developed serum sickness; among persons over 15 years of age, the incidence was 46%. | | | The use of homologous immunoglobulins for human post-exposure treatment virtually eliminates the risk of anaphylaxis and serum sickness associated with heterologous serum products. | | | This technique has been adapted for purifying heterologous immunoglobulins and was described in the third edition of Laboratory techniques in rabies. |
|
http://www.who.int/rabies/vaccines/other_rabies_biolog_product/en
|
|
| |
| | Journal of Drugs in Dermatology: Serum sickness due to infliximab in a patient with psoriasis |
| | The skin disorders that may be observed in patients with serum sickness include urticaria, purpura, maculopapular eruptions, and erythema multiforme. | | | However, most of the literature on the subject of serum sickness and serum sickness-like reactions appears to conform to the designations given by Buhner and Grant, who define serum sickness as the classic syndrome which occurs in response to an antigen that is derived from heterologous serum. | | | Journal of Drugs in Dermatology: Serum sickness due to infliximab in a patient with psoriasis |
|
http://findarticles.com/p/articles/mi_m0PDG/is_3_3/ai_n6056507
|
|
| |
| | NEJM -- A prospective clinical and immunologic analysis of patients with serum sickness |
| | This study documents the immunopathology of serum sickness in human beings and describes a cutaneous marker for the disease. | | | A prospective clinical and immunologic analysis of patients with serum sickness | | | NEJM -- A prospective clinical and immunologic analysis of patients with serum sickness |
|
http://content.nejm.org/cgi/content/abstract/311/22/1407
|
|
| |
| | serum sickness |
| | Plasma cleansing (plasmapheresis) is rarely used for severe serum sickness not responsive to the usual measures. | | | Now it is most often a manifestation of a drug allergy. | | | Serum sickness is usually an iatrogenous or iatrogenic (that is, produced by medical treatment) condition. |
|
http://www.drhull.com/EncyMaster/S/serum_sickness.html
|
|
| |
| | [No title] |
| | The good news is that after an episode of serum sickness or a more immediate allergic reaction to a medication, chronic headaches, fatigue and joint pain would not be expected. | | | My doctor tells me that I now have "serum sickness." I have joint pain and fatigue as well as headaches. | | | Treatment is supportive: removing the offending agent (such as a medication), reducing fever with acetaminophen, reducing pain with anti-inflammatory agents (such as ibuprofen or even corticosteroids) and waiting for the reaction to resolve. |
|
http://www.intelihealth.com/chn/medhelp/HA/00310535.htm
|
|
| |
| | Serum Sickness Associated |
| | A 43-year-old man with a 19-year history of Crohn's disease experienced serum sickness with acute lobular panniculitis and vasculitis within 2 weeks of initiating 6-mercaptopurine therapy. | | | He had no history of extraintestinal manifestations of Crohn's disease or drug allergy. | | | Serum Sickness Associated with 6-Mercaptopurine in a Patient with Crohn's Disease |
|
http://www.accp.com/pharmacotherapy/Abs17_1/P173.htm
|
|
| |
| | ePrints@UQ - Lack Of Neurological Abnormalities In Lewis Rats With Experimental Chronic Serum Sickness |
| | Immunofluorescence studies identified deposits of immunoglobulin in the choroid plexus of chronic serum sickness rats but not in controls. | | | We induced chronic serum sickness in the Lewis rat by daily intraperitoneal injections of bovine serum albumin (BSA) in male rats that had previously received footpad inoculations of BSA. | | | Serum sickness in man may occur after treatment with foreign proteins such as tetanus or diphtheria antisera, and in some patients leads to neurological complications such as neuropathy or encephalomyelitis. |
|
http://eprint.uq.edu.au/archive/00000889
|
|
| |
| | Dorlands Medical Dictionary |
| | athletes' sickness, weakness, blurred vision, nausea, and headache, following a short period of intense physical exercise. | | | altitude sickness, the condition resulting from difficulty in adjusting to diminished oxygen pressure at high altitudes. | | | Although serum sickness is now rare because of the replacement of most animal-derived antisera with human immune globulins, an identical illness ( serum sickness–like reaction or syndrome) can be produced by hypersensitivity reactions to penicillin and other drugs. |
|
http://www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszSzcommonzSzdorlandszSzdorlandzSzdmd_s_11zPzhtm
|
|
| |
| | Autoimmunity and Immune Complex Diseases |
| | The rabbit model of acute serum sickness can be transformed into chronic serum sickness if daily injections of BSA are made in order to maintain ICs in the circulation for an extended period. | | | 652 Valvular endocarditis in acute serum sickness of rabbit. | | | Manifestations of serum sickness, expressed as tissue injury and acute inflammation in multiple sites, develop during the immune phase of antigen elimination: glomerulonephritis (GN), vasculitis, synovitis, and endocarditis. |
|
http://edcenter.med.cornell.edu/CUMC_PathNotes/Immunopathology/Immuno_03.html
|
|
| |
| | California Dreaming |
| | Dixon's work at Pitt showed how our antibody response, which was thought to keep us healthy, could actually make us sick. | | | A new field, immunopathology, arose to describe what happens when our bodies' own defenses turn on us. | | | Because these symptoms are so similar to human diseases like rheumatoid arthritis, rheumatic fever, and lupus, serum sickness induced in experimental animals is a good model of human immunologic disease. |
|
http://www.leahkauffman.net/clips/cadreaming.html
|
|
| |
| | Serum Sickness: an immune complex reaction to foreign protein and drugs |
| | Serum sickness is usually self limiting and resolves over 2-3 weeks. | | | Serum sickness is a relatively rare condition in humans, related to the decrease in usage of foreign serum proteins in treatment of human disease, such as for treatment of snake or spider bite. | | | Serum sickness is rare in humans, related to the decrease in usage of foreign serum proteins such as for treatment of snake or spider bite. |
|
http://allergycapital.com.au/Pages/gpserum.html
|
|
| |
| | hypersensitivity: Information From Answers.com |
| | Anaphylaxis is the immediate, sometimes fatal hypersensitivity reaction to drugs or serum to which an individual has been previously sensitized. | | | Anaphylaxis, serum sickness, and delayed sensitivity may occur in otherwise normal, nonallergic individuals as well as allergics, as a response to substances that are highly sensitizing. | | | Delayed reaction allergies occur when cells of the immune system, the lymphocytes, that have previously been sensitized react to antigenic substance. |
|
http://www.answers.com/topic/hypersensitivity
|
|
| |
| | Re: One dose |
| | Did your doctor say it was serum sickness? | | | > Did your doctor say it was serum sickness? | | | I, too, believe it is an idiopathic form of serum sickness. |
|
http://www.rxlist.com/rxboard/levaquin.pl?read=1095
|
|
| |
| | Immune Complexes - Serum sickness |
| | The experimental model of serum sickness, usually studied with rabbits, has been developed by Lambert,Germuth and Dixon. | | | In the 1960ies Lambert and Dixon made several elegant animal experiments using radiolabled serum proteins conclusively demonstrating the association of the pathological lesions of serum sickness with the detection of circulating immune complexes (CIC). | | | The pathogenesis of this serum sickness was attributed to the host's immunological reaction to injected antigens and has been described as a generalized Arthus reaction. |
|
http://www.immune-complex.ch/experimentalpathology/serum_sickness.htm
|
|
| |
| | Search Results for sickness - Encyclopædia Britannica |
| | It is a condition in which the body is starved of oxygen because of the thinness... | | | sickness induced by motion and characterized by nausea. | | | The term motion sickness was proposed by J.A. Irwin in 1881 to provide a general designation for such similar syndromes as sea sickness, train... |
|
http://www.britannica.com/search?query=sickness&submit=Find&source=MWTEXT
|
|
| |
| | What is Serum Sickness |
| | Fetch Free Reports › Health › What is Serum Sickness | | | The patient may be allergic to certain immunization procedures and should be tested before receiving them. | | | Serum sickness is a response to certain injections which contain horse serum. |
|
http://www.fetchfreereports.com/health/freewhatisserumsickness0401.html
|
|
| |
| | Misdiagnosis of Underlying Causes of Serum sickness - CureResearch.com |
| | Underlying conditions list: The list of possible underlying conditions mentioned in various sources for Serum sickness includes: | | | These are other medical conditions that may possibly cause Serum sickness. | | | About underlying conditions: With a diagnosis of Serum sickness, it is important to consider whether there is an underlying condition causing Serum sickness. |
|
http://www.cureresearch.com/s/serum_sickness/underly_printer.htm
|
|
| |
| | Drug Reaction |
| | This practical information is made available by the Allergy Centre. | | | False drug reactions, causing generalized symptoms such as nausea, vomiting, sweating, headache, rapid heart beat and dry mouth have occurred with worried people, should not be confused with serum sickness, and subsides fairly quickly. | | | ACTIVE serum sickness from drugs or sera will reveal itself by |
|
http://www.allergycentre.com.au/id39.htm
|
|
| |
| | Re: Recovery from serum sickness caused by antibiotic |
| | Randy Stephens offers comprehensive drug reviews and personal medication consultations. | | | i avoid people and mostly people who are sick. | | | i get over the illness than i have to get over the serum sickness. |
|
http://www.medconsultant.com/clients/messages/1433.html
|
|
| |
| | March 30, 2000: RE: MED: Serum Sickness, UPDATE |
| | I had the HealthSquare site up and was reading about this > condition when my Rheumie called about 4:40pm. | | | As was explained to me, the whole immune > system > > is traumatized and is reacting systemically, the very serum in my tissues > is > > __?__. | | | It is a know trigger of > this serum sickness which I now have. |
|
http://www.hamline.edu/~lupus/arch2000/msg01546.html
|
|
| |
| | Serum sickness induced by bupropion -- Yolles et al. 33 (9): 931 -- The Annals of Pharmacotherapy |
| | DISCUSSION: A thorough search for other etiologies of the patient's symptoms was unrevealing, and a clinical diagnosis of serum sickness was made. | | | CONCLUSIONS: The previously unreported adverse drug reaction of serum sickness associated with the use of bupropion is demonstrated by this case, based on the temporal relationship and the results of stopping the drug, in light of no other identifiable etiology. | | | Given the temporal association between the illness and the introduction of bupropion, this was felt to be the causal agent. |
|
http://www.theannals.com/cgi/content/abstract/33/9/931
|
|
| |
| | Anti-Epileptic Medication Adverse Effects - 2000 |
| | Return to The Intern in the Middle of the Night Home Page | | | Systemic Adverse Effects - Gingival hypertrophy, body hair increase, lymphadenopathy, risk of rash in approximately 10% of patients | | | Neurotoxic Adverse Effects - Alteration of sleep cycles, sedation, lethargy, ataxia, behavioral changes, hyperactivity, tolerance, dependence |
|
http://lib-sh.lsuhsc.edu/fammed/intern/sideffct.html
|
|
| |
| | Serum sickness |
| | While this finding does not affect the way the person with the reaction is treated (serum sickness and this reaction are treated the same way), it does mean that the person who has the reaction may not be at any greater risk for being allergic to other antibiotics. | | | Dawn, the symptoms you describe your son having are typical of a serum sickness like reaction. | | | In 1994, researchers figured out that while the reaction to cefaclor looks very similar to serum sickness, it is probably not caused by the same immune response mechanisms. |
|
http://parenting.ivillage.com/tp/tphealth/0,,3qg6,00.html
|
|
| |
| | Serum Sickness - New Treatments, January 22, 2005 |
| | The use of horse serum or other animal serum in therapy should be limited to cases for which no alternative is available. | | | The serum sickness syndrome is a characteristic systemic immunologic disorder that follows the administration of a foreign material or medication. | | | Serum sickness is the classic example of a type III hypersensitivity, "immune complex" disease. |
|
http://www.ccspublishing.com/journals3a/serum_sickness.htm
|
|
| |
| | Symptoms of Serum sickness - WrongDiagnosis.com |
| | Furthermore, symptoms of Serum sickness may vary on an individual basis for each patient. | | | This symptom information has been gathered from various sources, may not be fully accurate, and may not be the full list of symptoms of Serum sickness. | | | General information about symptoms of Serum sickness: The symptom information on this page attempts to provide a list of some possible symptoms of Serum sickness. |
|
http://www.wrongdiagnosis.com/s/serum_sickness/symptoms.htm
|
|
| |
| | Serum Sickness |
| | Repeated exposure to an agent in the same class will result in a secondary immune response, meaning that serum sickness will develop more quickly and potentially be more severe (3). | | | The treatment of serum sickness revolves around antihistamines, antipyretics, anti-inflammatory medications and possibly corticosteroid administration. | | | Currently, there are several known medications which can incite this reaction. |
|
http://web2.chm.msu.edu/em/serumsickness.htm
|
|
| |
| | [No title] |
| | Apnea caused by SUCCINYLCHOLINE in patients with abnormal serum cholinesterase. | | | But, drugs such as penicillin, sulfonamides, phenytoin, streptomycin, etc. can also occasionally cause serum sickness. | | | Serum sickness involves IgG as well as IgE and is a Ag-Ab complex mediated reaction. |
|
http://www.kumc.edu/research/medicine/pharmacology/CAI/webCAI/blk1/allidio.wbc
|
|
| |
| | HON Allergy Glossary Serum Sickness |
| | Serum sickness was originally induced following therapy with large doses of antibody from a foreign source, e.g. | | | A hypersensitivity reaction consisting of fever, rashes, joint pain and glomerulonephritis, resulting from localization of circulating, soluble, antigen-antibody complexes, which induce inflammatory reactions. |
|
http://www.hon.ch/Library/Theme/Allergy/Glossary/serum_sickness.html
|
|
| |
| | Hypersensitivity diseases. |
| | This illness was so named because it frequently followed the administration of therapeutic horse antiserum. | | | Serum sickness is nowadays seen after the use of anti-lymphocyte globulin, employed as an immunosuppressive agent in transplant recipients, and also, rarely, after the administration of streptokinase, a bacterial enzyme that is used as a thrombolytic agent to treat patients with a myocardial infarction or heart attack. | | | Serum sickness after a second dose of antigen follows the kinetics of a secondary antibody response and the onset of disease occurs typically within a day or two. |
|
http://www.ncbi.nlm.nih.gov/books/bv.fcgi?tool=bookshelf&call=bv.View..ShowSection&searchterm=hypersensitivity&rid=imm.section.1756
|
|
| |
| | Glossary |
| | Besides SERUM SICKNESS and the ARTHUS REACTION, evidence supports a pathogenic role for immune complexes in many other systemic immunologic diseases including GLOMERULONEPHRITIS, systemic lupus Erythematosus (LUPUS Erythematosus, SYSTEMIC) and polyarteritis nodosa. | | | When they are complexed to protein carriers, some drugs can also cause serum sickness when they act as haptens inducing antibody responses. | | | It is characterized by pulmonary infiltrates, eosinophilia, elevated serum IgE and immediate type skin reactivity to aspergillus antigen. |
|
http://nationaljewish.org/fp10.html
|
|
| |
| | THE MERCK MANUAL, Sec. 12, Ch. 148, Hypersensitivity Disorders |
| | Conditions in which immune complexes (ICs) appear to play some role are serum sickness due to serum, drugs, or viral hepatitis antigen; SLE; RA; polyarteritis; cryoglobulinemia; hypersensitivity pneumonitis; bronchopulmonary aspergillosis; acute glomerulonephritis; chronic membranoproliferative glomerulonephritis; and associated renal disease (see Ch. | | | In bronchopulmonary aspergillosis, drug- or serum-induced serum sickness, and some forms of renal disease, an IgE-mediated reaction is thought to precede the type III reaction. | | | Rarely, both antigen and antibody can be detected by immunofluorescence in the inflamed tissue--this has been shown in the renal disease of SLE and in the vasculitic lesions of hepatitis-antigen-associated serum sickness. |
|
http://www.merck.com/mrkshared/mmanual/section12/chapter148/148d.jsp
|
|
|
