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| | Sensory Processing Lab |
 | | This laboratory is intended to illustrate some basic principles of sensory processing by the brain, and to give you the background and some incentive to further explore them on your own. | | | The general concern of this laboratory session was to better understand what must be going on in the brain after the sensory transduction processes in the retina in order to produce the "picture in your head". | | | The general question under investigation is the nature of the central information processing steps which intervene between the initial stages of sensory transduction and the appreciation of a sensory percept. |
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http://serendip.brynmawr.edu/bbl/Sensorylab.html
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| | A. James Hudspeth |
| | Neurons in a sensory ganglion that also develops from the otic placode extend their axons along the pathway blazed by the primordium, innervating each hair cell that they encounter. | | | Because of its location on the animal's surface and its origin early in larval development, the lateral line is readily amenable to observation and experimental intervention. | | | Whole-cell recording discloses that the positive phase of movement is associated with the opening of transduction channels. |
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http://www.hhmi.org/research/investigators/hudspeth.html
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| | SENSORY SYSTEMS |
| | Secondary sensory neurons cross over the midline at the level of the spinal cord and ascend to the brain in the anterolateral pathway which is along the anterior and lateral portion of the spinal cord. | | | Unlike the neurons in the dorsal column pathway the majority of primary sensory neurons in this pathway synapse with secondary sensory neurons located in the spinal cord in the substantia gelatinosa (the uppermost layers of the dorsal horn). | | | The area of skin that a sensory neuron innervates is the receptive field for that particular neuron. |
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http://www.bioweb.uncc.edu/humanphys/sensory.htm
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| | Psyc. 358 Lecture - Sensory receptors |
| | neurons in a sensory pathway vary in their sensitivity to a stimulus | | | when absorption of light changes the shape of the retinal, the shape of the opsin is changed as well, triggering the second stage of transduction | | | the process of changing energy from one form to another is called "transduction" |
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http://artsci-ccwin.concordia.ca/psychology/psyc358/Lectures/vision.htm
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| | Faculty Profile Template |
| | These results suggests a similarity between VNO sensory transduction and invertebrate phototransduction and provide a framework to guide our future investigations. | | | Recent work by ourselves and others has begun to shed light on the mechanism of VNO sensory transduction. | | | Current research in the lab is focused on understanding the vomeronasal organ (VNO), which is the primary site for pheromone detection in most vertebrates. |
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http://www.usc.edu/dept/LAS/biosci/faculty/liman.html
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| | Sensation(al) positions at Stanford |
| | elegans neurons, and heterologous expression of sensory transduction channels. | | | The lab uses three approaches to study molecular events that give rise to sensation: quantitative behavioral analysis, in vivo electrophysiology of wild-type and mutant C. | | | Postdoctoral applicants should have experience with at least one of the following: C. |
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http://elegans.swmed.edu/Announcements/goodman_posns.html
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| | 2004 GRC on Photosensory Receptors & Signal Transduction |
| | This Conference is expected to provide a forum for stimulating and intense discussion of mechanistic insights and general principles emerging from the cutting edge research in photosensory signal transduction. | | | Function of Chlamydomonas sensory rhodopsins in photomotile responses | | | Modification of light signal transduction pathways by two-component systems in Arabidopsis |
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http://www.grc.org/programs/2004/photosen.htm
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| | Research Links |
| | Sending and receiving signals from the brain—both to sensory organs and muscles—is dependent on intact healthy nervous pathways that often travel through the spinal cord. | | | Their site describes common taste and smell disorders and current research into the physiological mechanisms of the two senses. | | | This article describes modern methods that may enable doctors to repair spinal cord damage and enable people with injuries and nerve disorders to lead normal lives. |
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http://wps.prenhall.com/esm_freeman_biosci_1/0,6452,500911-,00.html
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| | Brain and Sensory Systems |
| | CNS sensory centers (emphasis on thalamus and sensory areas of cerebral cortex) | | | What does sensory processing in the cerebral cortex do for us that sensory | | | What do referred pain and phantom limb pain say about sensory processing in the human CNS? |
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http://www.indiana.edu/~phys215/lecture/lecnotes/chap108N.html
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| | Jeffery F. Miller, Ph.D. |
| | These models provide us with an opportunity to analyze colonization, pathogenesis, the immune response, and the role of sensory transduction in the context of a natural host-parasite interaction. | | | We are using information from in vitro studies to construct Bordetella strains with altered BvgAS signal transduction systems for in vivo analysis in rabbits and rats. | | | Biochemical and genetic approaches are being used to determine the mechanism of transmembrane signal transduction mediated by BvgAS. |
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http://www.cnsi.ucla.edu/faculty/miller_j.htm
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| | PSY 312 |
| | Typically includes basic neuroanatomy, neural transmission, sensory transduction, genetics, sexual behavior, emotion, hunger, sleep, learning and memory. | | | Purpose of the Course: To present students with current research into the neurological substrates of behavior and psychological phenomena. | | | 7.2 Students will be able to explain the process of sensory transduction in the visual and auditory systems. |
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http://www.lourdes.edu/Outline/Psychology/PSY312.htm
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| | Biology 444: Sensory Biology |
| | This course will focus on eachaspect ofthis process for each sensory modality. | | | 4 Olfaction: peripheral mechanisms and transduction, and centralprojections | | | 23 and 24 Integration of Sensory Biology principles |
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http://academic.uofs.edu/faculty/gomezg2/Bio444.htm
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| | Transduction channels |
| | Proteins involved in transduction are exquisitely tuned to their respective sensory modality and hence allow the perception of extremely weak stimuli such as a few photons, a few odour molecules, or mechanical translocations on the scale of a few atoms. | | | Chapter 6: Transduction channels in the vomeronasal organ | | | Thus, new experiments on transduction channels of photoreceptors, olfactory sensory neurons, taste cells, mechanoreceptors as well as receptors for temperature and pain provide the first comprehensive models for sensory function. |
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http://www.transduction-channels.net
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| | The Program in Biomedical Sciences (PIBS) - Signal Transduction |
| | Helen Baghdoyan, Ph.D. Signal transduction pathways regulating arousal states such as sleep and anesthesia. | | | Ruthann Nichols, Ph.D. Structure-activity relationship of neuropeptides and neuropeptide receptors with emphasis on the RFamide peptide family and their role in regulating heart rate and muscle contraction; role of FMRF-amide neuropeptides in Drosophila and mammalian nervous systems. | | | Benjamin L. Margolis, MD Mechanisms of signal transduction by tyrosine kinases. |
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http://www.med.umich.edu/pibs/faculty/signal.htm
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| | ScienceWeek |
| | Deflection changes tension in all elements of the system, and the transduction channel responds by changing its open probability. | | | A notable success was the discovery that flies rely on NompC, another TRP channel, to detect movement of their sensory bristles -- small hairs that decorate their bodies(4). | | | A general model --borrowed from worm touch receptors(1,2) and hair cells(3) --applies to many mechanosensory transduction systems: its key feature is a transduction channel that detects deflection of an external structure relative to an internal structure, such as the cytoskeleton. |
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http://www.scienceweek.com/2003/scc031107-1.htm
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| | Neuroscience Graduate Program @ Univeristy of Southern California |
| | Our work was the first to suggest that a channel in the TRPC family plays a role in vertebrate sensory transduction. | | | Liman, E.R. and H. Innan, Relaxed selective pressure on an essential component of pheromone transduction in primate evolution. | | | Projects in the lab focus on understanding the role of various TRP channels in sensory transduction and the second messenger signaling pathways that regulate these channels. |
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http://www.usc.edu/dept/nbio/ngp/Faculty/liman-er.shtml
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| | Chapter 9 notes |
| | What does sensory nerve activity give rise to one particular subjective sensation? | | | Does the "law of specific nerve energies" arise because each sensory nerve only responsds to one type of stimulus energy? | | | What names are used to categorize sensory receptors based on the type of energy to which they are most sensitive? |
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http://soma.npa.uiuc.edu/courses/bio303/Chapter9_notes.htm
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| | Lecture Outline: Sensory Systems, Bio102 |
| | Touch (pressure) sensitive sensory neurons all over body | | | Consider what the animal does with the information (behaviorally). | | | B. Sensory neurons are effectively organized as sampling devices |
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http://www.biol.sc.edu/courses/bio102/37-ol.html
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| | eMedicine - Cochlear Function, General : Article Excerpt by: Michael J Ruckenstein, MD, MSc, FACS, FRCSC |
| | The focus of this article is applied physiology of the inner ear, emphasizing the processes involved in transduction and the homeostatic mechanisms necessary for maintaining the inner ear in a functional state | | | Synonyms, Key Words, and Related Terms: cochlear physiology, inner ear function, sensory transduction process, inner ear physiology, inner ear anatomy, ear function, ear anatomy, ear physiology, inner ear physiology, cochlea physiology, cochlea, cochlea function, audiology, auditory system, electrocochleography | | | While performing this sensory transduction process, the inner ear analyzes a sound stimulus in terms of its frequency, intensity, and temporal properties, and it transmits this information to the CNS for further processing and interpretation. |
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http://www.emedicine.com/ent/byname/cochlear-function-general.htm
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| | HHMI News: Channel Protein Converts Vibrations to Electrical Signal |
| | “We thought the TRP family was a likely place to look for this channel, because many other TRP channels are involved in sensory transduction,” Corey said. | | | And if TRPA1 is the right channel, it should go away.” In fact, TRPA1 did disappear when the tip links were removed — further evidence for a role in that signaling pathway. | | | Corey, who is at Harvard Medical School, have several lines of evidence that, in vertebrates, this mechanosensitive channel is formed by a protein known as TRPA1. |
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http://www.hhmi.org/news/coreydp.html
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| | Amazon.ca: Books: Transduction Channels in Sensory Cells |
| | Required reading for biologists, physiologists and medical researchers with an interest in sensory physiology. | | | Look for books like Transduction Channels in Sensory Cells by subject: | | | This is the first book to provide a molecular level explanation of how the senses work, linking molecular biology with sensory physiology to deduce the molecular mechanism of a key step in sensory signal generation. |
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http://www.amazon.ca/exec/obidos/ASIN/3527308369
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| | INTRODUCTION TO SENSORY TRANSDUCTION |
| | Regardless of what is detected sensory systems follow the same sensory transduction pathway: Detect--->Amplify--->Signal. | | | Sensory transduction, the ability to detect and translate a stimulus, is an indispensable part of our lives. | | | There are may classification systems for sensory receptors, one is particularly useful. |
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http://www.alsa-or.org/research/sensintro.htm
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| | A novel mode of sensory transduction in archaea: binding protein-mediated chemotaxis towards osmoprotectants and amino ... |
| | Zhang,X.N., Zhu,J.Y. and Spudich,J.L. (1999a) The specificity of interaction of archaeal transducers with their cognate sensory rhodopsins is determined by their transmembrane helices. | | | Present address: Division of Endocrinology, Beth Israel Diaconess Medical Center and Department of Medicine, Harvard Medical School, Boston, MA 02215, USA | | | Yao,V.J. and Spudich,J.L. (1992) Primary structure of an archaebacterial transducer, a methyl-accepting protein associated with sensory rhodopsin I. Proc. |
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http://www.emboj.org/cgi/content/full/21/10/2312
(5593 words)
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| | M. Robert Belas |
| | This research may be divided into six projects: 1) bacterial associations; 2) eukaryotic associations; 3) physiological interactions; 4) sensory transduction; 5) biosensor development; and, 6) coral bleaching. | | | Swarming motility and behavior are complex processes that involves cell-cell contact, communication, and signal transduction leading to the development of a monospecific biofilm. | | | The goal of this research is to elucidate the molecular mechanisms used by the bacteria in these processes. |
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http://www.umbi.umd.edu/~comb/faculty/belas/belas.html
(673 words)
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| | The ChemoReception Web |
| | The vomeronasal organ (VNO) of terrestrial vertebrates plays a key role in the detection of pheromones, chemicals released by animals that elicit stereotyped sexual and aggressive behaviors among conspecifics. | | | Sensory transduction in the VNO appears unrelated to that in the vertebrate olfactory and visual systems: the putative pheromone receptors of the VNO are evolutionarily independent from the odorant receptors and, in contrast to vertebrate visual and olfactory transduction, vomeronasal transduction is unlikely to be mediated by cyclic-nucleotide-gated channels. | | | We hypothesized that sensory transduction in the VNO might instead involve an ion channel of the transient receptor potential (TRP) family, members of which mediate cyclic-nucleotide-independent sensory responses in Drosophila melanogaster and Caenorhabditis elegans and play unknown functions in mammals. |
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http://md1.csa.com/crw/1999/vno02.html
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| | GMS 6002: Section 8, Lecture 11 |
| | The physiological and anatomical principals common to sensory systems will be emphasized. | | | My goal is to help provide students a framework for thinking about how the nervous system detects and begins to process sensory information. | | | The discussion will emphasize what we think we know about sensory responses at the level of receptor cells and the initial steps in information processing in vision and the chemical senses (olfaction and taste). |
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http://www.med.ufl.edu/IDP/core98/Outln8/S8l11.html
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| | Charles S. Zuker |
| | The senses of vision, hearing, touch, olfaction, and taste have the critical roles of providing the organism with a faithful representation of the external world. | | | Summary: Charles Zuker's laboratory is using a combined molecular, genetic, and physiological approach to study signal processing, information transfer, and coding mechanisms in sensory systems. | | | We use a combined molecular, genetic, and physiological approach to investigate the biology of sensory transduction mechanisms in photoreceptors, mechanoreceptors, and taste receptors. |
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http://www.hhmi.org/research/investigators/zuker.html
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| | WormBase - Home Page |
| | Meeting 2: Behavior and Sensory Transduction, Neuronal Development, and Synaptic Function (Organizers: Maureen Barr, Ahna Skop and others). | | | Meeting 3 (Genomics, RNAi, & Gene Expression) and Meeting 4 (Aging and Stress, Dauer and Developmental Timing, Cell Death & Neurodegeneration, and Pathogenesis) will be added in 2008. |
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http://www.wormbase.org
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| | Nature web focus: Sensory Transduction |
| | LETTERS TO single population of olfactory sensory neurons mediates an innate avoidance behaviour in Drosophila | | | It is the first and perhaps most crucial step in sensory processing, and takes place in specialized cells that possess finely tuned transduction mechanisms. | | | The transduction of environmental stimuli into a cellular response is known as sensory transduction. |
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http://www.nature.com/nature/focus/sensorytransduction
(702 words)
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| | NEUR 516 |
| | Lecture 1: Structure and function of the retina and central visual pathways (Wu). | | | This course will be useful for graduate students and postdocs in Neuroscience, Physiology, Biochemistry, Cell Biology and Molecular Genetics who are interested in the visual system, other sensory systems or brain function. | | | This is a new course that, for Baylor students, is actually two shorter courses called "Sensory Transduction" and "Physiology of the Visual System". |
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http://www.ruf.rice.edu/~neurosci/bcmsyllabi/neur516.htm
(415 words)
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| | Enjoyable Gut Neuroscience |
| | The goal of my research is to understand the neuronal basis of disease with an emphasis on the compounds ATP & serotonin (5‑HT) and the roles they play in neurotransmission & sensory transduction. | | | My laboratory focuses on the neurophysiology of the gastrointestinal tract using electrochemical methods. | | | Feel free to email me with any questions. |
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http://paul-bertrand.com
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| | 2004 GRC on Sensory Transduction In Microorganisms |
| | "Sensory rhodopsins: signaling mechanisms in archaea, cyanobacteria, and eukaryotic microorganisms" | | | "Multiple convergent signal transduction pathways control initiation of fruiting body morphogenesis in M. |
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http://www.grc.uri.edu/programs/2004/senstran.htm
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| | Roberto Marangoni |
| | Roberto Marangoni is part of the research group on Photoreception and sensory transduction in microorganisms and Biological effects of UV radiation |
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http://www.ib.pi.cnr.it/staff/roberto.marangoni.html
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| | Sensory receptor - Wikipedia, the free encyclopedia |
| | In a sensory system, a sensory receptor is a structure that recognizes a stimulus in the internal or external environment of an organism. | | | The sensory receptor functions as the first component in a sensory system. | | | Some types of mechanoreceptors fire action potentials when their membranes are physically streched. |
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http://en.wikipedia.org/wiki/Sensory_receptor
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| | David Zusman |
| | We are currently using molecular and genetic techniques to search for other members of this interesting signal transduction pathway. | | | Directed movement is useful for feeding and necessary for development. | | | Extracellular polysaccharides mediate pilus retraction during social motility of Myxococcus xanthus. |
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http://mcb.berkeley.edu/faculty/BMB/zusmand.html
(704 words)
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| | Stimulus transduction |
| | Research focuses on signaling pathways activated in the nervous system during development, disease and aging. | | | Signal Transduction in the Nervous System Signal Transduction Laboratory at East Carolina University Brody School of Medicine. | | | Signal Transduction - Receptors, Mediators and Genes Journal for critical discussions in the multifaceted field of signal transduction mechanisms. |
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http://www.serebella.com/encyclopedia/article-Stimulus_transduction.html
(257 words)
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| | Yale- Cranial Nerve 2, pg. 3 |
| | The bipolar cells are the primary sensory neurons of the visual pathway. | | | This hyperpolarization of the photoreceptor cell can produce either an excitatory (depolarization) or inhibitory (hyperpolarization) response by the bipolar cell dependent on the nature of the synapse between the two cells. | | | They synapse with and either excite or inhibit the action potential firing rate of the secondary sensory neurons - the ganglion cells. |
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http://info.med.yale.edu/caim/cnerves/cn2/cn2_3.html
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| | Sensory Transduction |
| | This process, called sensory transduction, began to be understood only recently, as a result of the development of the techniques of patch-clamp recording and gene cloning. | | | Transduction Channels in Sensory Cells Related Subjects Biopolymers Biotechnology General Analytical Chemistry General... | | | Author By ISBN By ISSN Wiley > Life and Medical Sciences > Cell and Molecular Biology > Transduction Channels in Sensory Cells Related Subjects Biopolymers Biotechnology General Analytical Chemistry General... |
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http://www.globalcellularrental.com/books-plain/0878931716.html
(582 words)
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