Secretin - Medicow
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Topic: Secretin



  
 Information on Secretin
Of course, to prove scientifically that secretin is beneficial in the treatment of autism, randomized, double-blind, placebo-controlled studies should be conducted.
The events surrounding Secretin have mirrored the history of autism "research" in that parents, at great emotional and financial expense, are encouraged to try some new "therapy" that has no real data to support its use.
Secretin has been known for at least 20 years and it has a variety of functions but not much in the way of medical uses.
http://www.unc.edu/~cory/autism-info/auti0020.html   (5612 words)

  
 Study Shows Secretin Fails to Benefit Children with Autism
For each of the 16 measures of the children's behavior, the secretin treatment did not result in any more statistically significant improvements in behavior than did treatment with the placebo.
The study authors said that the attention surrounding media reports of secretin may have been responsible for the seeming improvements in the placebo group.
For this reason, it is theoretically possible that individuals who were not able to take part in the study might benefit from secretin.
http://www.nichd.nih.gov/new/releases/secretin1299.cfm   (937 words)

  
 Autism - Transdermal Secretin
If the duodenum's inability to produce secretin is caused by ongoing measles virus activity in the intestine, the elimination/control of the virus with the bath treatment may make the secretin treatment no longer necessary.
With James's history of allergies human synthetic secretin was the most responsible choice in case he wold be allergic to any of the properties of the porcine product.
Infusions inherently involve an invasive treatment and a large pulse of secretin that may give the patient problems.
http://www.krysalis-sparx.com/autism.htm   (14791 words)

  
 Secretin Facilitates GABA Transmission in the Cerebellum -- Yung et al. 21 (18): 7063 -- Journal of Neuroscience
that secretin serves as a neuropeptide in the rat brain.
Secretin facilitates GABAergic, but not glutamatergic, synaptic transmission in the rat cerebellum.
The mechanism by which secretin facilitates GABA release was examined in another series of experiments, which were focused
http://www.jneurosci.org/cgi/content/full/21/18/7063   (4110 words)

  
 Treatments for Autism: Secretin for Autistic Children
Remember the secretin will help to take out what the body does not need.
The way it is applied is thought to have much to do with its effectiveness.
Another perspective, with a biochemist parent's interpretation is available from the National Alliance for Autism Research.
http://www.healing-arts.org/children/secretin.htm   (862 words)

  
 AUTISM: SUPPLEMENTS, DIETS & ANTACIDS (NOT SECRETIN)
The study was interrupted by 2 children being placed on prescribed drugs.
One used Ritalin successfully for a time and the other used secretin, which did not seem beneficial.
Very good means parents, teachers and I agreed that the children settled into their classrooms and homes without any major lasting behavioural problems, and they made a major jump in their behavioural, social and educational functioning.
http://www.autism.firman.btinternet.co.uk   (3745 words)

  
 Secretin Receptors in Normal and Diseased Human Pancreas: Marked Reduction of Receptor Binding in Ductal Neoplasia -- ...
rat secretin in the presence of 100 nmol/L unlabeled human secretin.
that it corresponds to the spliced variant of the human secretin
rat secretin by human secretin (•; A–D) and porcine secretin (
http://ajp.amjpathol.org/cgi/content/full/167/4/959   (4253 words)

  
 Autism Research Institute
On January 5, 2004, the Repligen Corporation released the long-awaited preliminary results of its Phase III study of secretin efficacy in autism.
That is why you had to use essentially useless criteria for selecting subjects for the Phase III research.
The negative report contrasted sharply with a great deal of very positive earlier data, and with Herlihy’s previously expressed enthusiasm for secretin.
http://www.autismwebsite.com/ari/newsletter/controversycontinues.htm   (1081 words)

  
 Center for the Study of Autism
Additionally, recent studies have shown secretin to be present in the amygdala, hippocampus and cerebellum--three areas of the brain that are known to be defective in autism.
With respect to research, there have been several one-dose safety studies on secretin, and these studies have found no differences between the experimental (secretin) and control groups, indicating that the side-effects are minimal.
Secretin is a hormone that is found in the pancreas, liver, upper intestinal tract, and brain.
http://www.autism.org/secretin.html   (230 words)

  
 Secretin
Secretin is secreted in response to one known stimulus: acidification of the duodenum, which occurs most commonly when liquified ingesta from the stomach are released into the small intestine.
Secretin functions as a type of fireman: it is released in response to acid in the small intestine, and stimulates the pancreas to release a flood of bicarbonate base, which neutralizes the acid.
The sequence of the mature peptide is related to that of glucagon, vasoactive intestinal peptide and gastric inhibitory peptide.
http://arbl.cvmbs.colostate.edu/hbooks/pathphys/endocrine/gi/secretin.html   (288 words)

  
 Information about Secretin
Because its safety and efficacy have not been adequately tested for treating autism, the National Institutes of Health does not currently have a formal position on the therapeutic use of secretin for the treatment of autism.
This web page links to the Autism Research Institute's statement about the use of secretin.
Because of the great interest being expressed by people throughout New York about the hormone secretin and its possible benefits for children with autism, we are providing a number of different sources of information.
http://www.albany.edu/psy/autism/secrt.html   (240 words)

  
 Secretin - Wikipedia, the free encyclopedia
Secretin was the first substance which was identified to cause a physiological effect in the body after being transported via the blood.
This helps neutralize the pH of the digestive products entering the duodenum from the stomach, as enzymes from the pancreas (eg, pancreatic amylase and pancreatic lipase) function optimally at neutral pH.
Secretin is a peptide hormone produced in the S cells of the duodenum.
http://en.wikipedia.org/wiki/Secretin   (241 words)

  
 Sudden Onset of Colitis After Ablation of Secretin-Expressing Lymphocytes in Transgenic Mice -- Rindi et al. 229 (8): ...
Secretin RNA is Present in Thymus and Spleen Lymphocytes.
Secretin: structure of the precursor and tissue distribution of the mRNA.
chronic administration of secretin proved not to cause any significant
http://www.ebmonline.org/cgi/content/full/229/8/826   (4690 words)

  
 Secretin antibodies from RDI Divison of Fitzgerald Industries Intl
Description/Specificity Secretin producing cells are the most frequently found in the proximal part of the duodenum and in the jejunum.
Please inquire for other applications or types of antibodies not listed below.
The antibody can be used for the diagnosis of tumors derived from these cells.
http://www.researchd.com/miscabs/secretin.htm   (119 words)

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