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| | Update on Testing for Scrapie, VME-0004-01 |
 | | Scrapie in sheep is characterized initially by subtle changes in behavior and gait. | | | Genetic testing for susceptibility (to clinical scrapie) and using the result for animal selection is currently being practiced by many breeders. | | | This ewe shows the weight loss and behavioral changes associated with scrapie. |
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http://ohioline.osu.edu/vme-fact/0004.html
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| | Sheep Feed and Scrapie, France CDC EID |
| | Moreover, scrapie is contagious in natural conditions (2). | | | Although in the past scrapie has not been considered a zoonosis, the emergence of bovine spongiform encephalopathy, transmissible to humans and experimentally to sheep, indicates that risk exists for small ruminant TSEs in humans. | | | Sigurdarson S. Epidemiology of scrapie in Iceland and experience with control measures. |
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http://www.cdc.gov/ncidod/EID/vol11no08/04-1223.htm
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| | Prions, BSE, CJD, Kuru Scrapie |
| | Australia is free of scrapie but the incidence of CJD is similar to scrapie affected countries. | | | It is of some concern that the incidence of previous surgery or other neurological diseases seem to be increased in patients with CJD compared to the normal population. | | | All attempts to transmit scrapie to guinea pigs, rats, and certain other primates (especially the chimpanzee) have failed. |
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http://virology-online.com/viruses/PRIONS.htm
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| | Prion Disease: US Declares Scrapie Emergency |
| | If these results are confirmed, it could mean that researchers and farmers may soon be able to write the final chapter on this deadly disease's 250-year history and the human health concerns that have become an unsettling subtext to the story. | | | This could simply mean the ARR genotype was never all that resistant to scrapie to begin with, only to a few common strains tested. | | | Opinion (webmaster): Scrapie eradication has been attempted many times in the past by various countries to little effect. |
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http://www.mad-cow.org/00/apr00_scrapie.html
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| | Scrapie - Frequently Asked Questions |
| | There is no scientific evidence to indicate that scrapie poses a risk to human health. | | | Due to damage to nerve cells, affected animals usually show behavioral changes, tremor (especially of head and neck), pruritus, and locomotor incoordination that progresses to recumbency and death. | | | If you have questions regarding the program please call Dr. Kris Petrini at 651-296-2942 (extension 31). |
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http://www.bah.state.mn.us/diseases/scrapie/scrapie_faq.htm
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| | TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES |
| | This strain has been isolated from the majority of the 20 natural scrapie sources studied in the past. | | | These are currently being studied and will be used in 'chain shuffling' techniques to recover combining sites closer to those used in the high affinity in-vivo immune response. | | | Three of the experiments are complete and two are still in progress. |
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http://eagle.westnet.gr/~aesclep/3wtse.htm
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| | The Prion Diseases |
| | They also become irritable and, in some cases, develop an intense itch that leads them to scrape off their wool or hair (hence the name "scrapie"). | | | Fortunately, work on a different problem led us to an alternative approach for demonstrating that prions could transmit scrapie without the help of any accompanying nucleic acid. | | | The result also lent support to earlier indications--uncovered by Shu-Lian Yang in DeArmond's laboratory and Albert Taraboulos in my group--that molecules made by the host can influence the behavior of scrapie PrP. |
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http://www.cyber-dyne.com/~tom/prionSP.html
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| | The rationale for ridding U.S. of scrapie - May 1, 2002 |
| | The scrapie prion is thought to be spread most commonly from the ewe to her offspring and to other lambs in contemporary lambing groups through ingestion of the placenta and placental fluids or cutaneously through abraded skin. | | | Hence, it would be in many tissues, from the lymph nodes to the peripheral nerves. | | | For us to have scrapie and chronic wasting disease is a big stigma for our trade. |
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http://www.avma.org/onlnews/javma/may02/s050102g.asp
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| | Cornell Sheep Program - Scrapie genetics |
| | Early signs of scrapie include subtle changes in behavior and temperament. | | | Scrapie is not caused by a particular genotype. | | | This is a major area of research, and some promising live-animal tests are in the development and evaluation stages. |
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http://www.sheep.cornell.edu/sheep/management/health/scrapiegenetics.htm
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| | Scrapies Eradication |
| | While scrapie is always fatal, it may take up to six years or longer before clinical signs are even apparent. | | | Scrapie is a degenerative and eventually fatal disease affecting the central nervous system. | | | There is currently no officially approved live test for scrapie, and the only way to positively detect the disease is by conducting a postmortem microscopic examination of the brain. |
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http://www.aces.edu/dept/extcomm/newspaper/nov29a01.html
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| | Prion Diseases |
| | Using this technique it is very clear that the recent outbreaks of new TSE diseases in various animals is caused by a prion with very similar characteristics ie BSE and quite distinct from previously recognized scrapie prion strains. | | | the prion is known as PrPsc (for scrapie) which is relatively resistant to proteases and accumulates in cytoplasmic vesicles of diseased individuals. | | | Antipodean sheep have also been bought back to the UK and maintained in quarantine conditions and not developed scrapie. |
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http://www-micro.msb.le.ac.uk/3035/prions.html
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| | Universe Magazine - Scrapie Test for Sheep Story |
| | Currently there are thought to be at least two cases of human TSEs that were transmitted by surgical instruments that had been cleaned and sterilized. | | | Scrapie is also related to the fatal human spongiform encephalopathy known as Creutzfeldt-Jacob disease. | | | The urgency to eradicate scrapie becomes clearer when one understands a bit more about this family of diseases. |
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http://www.wsu.edu/NIS/Universe/SheepSt.html
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| | Fight Scrapie |
| | Guidelines include separating enrolled sheep from nonenrolled sheep by a vacant pen, barn alley, or solid barrier sufficient to prevent physical contact. | | | Because there is no validated live-animal test for this disease and scrapie has a long incubation period, a flock is considered free of the disease if no sheep have been diagnosed with scrapie and there is no clinical evidence of it over a period of time. | | | Submit to an official laboratory tissues from scrapie-suspect animals and from animals suspected of having other neurologic or chronic, debilitating illnesses. |
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http://www.osranch.com/Scrapie.htm
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| | Scrapie (Mad Sheep Disease) May Pose a Risk to Humans |
| | "The main evidence that scrapie does not affect humans has been | | | Scrapie has been around for centuries and until now there has been no | | | But there are more than 20 strains of scrapie, and six of sCJD. |
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http://www.organicconsumers.org/meat/scrapiecjd.cfm
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| | Cell -- Horwich and Weissman 89 (4):499 |
| | Jarrett, J.T., and Lansbury, P.T. Seeding "one-dimensional-crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie? | | | Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain. | | | Borchelt, D.R., Taraboulos, A., and Prusiner, S.B. Evidence for synthesis of scrapie prion proteins in the endocytic pathway. |
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http://www.sciencedigest.org/499.HTM
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| | Hawks Mountain Ranch~Infomration about Scrapie in Sheep and Goats |
| | Scrapie is a slowly progressive disease causing degeneration of the central nervous system of sheep and goats characterized by behavioral changes, tremor (especially of head and neck) and uncoordinated movements which progress to prostration and death. | | | Kuru and Creutzfeldt-Jakob disease are human diseases similar to scrapie but not related. | | | Scrapie does not stimulate the immune system: therefore, there is no current blood test for preclinical diagnosis. |
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http://www.hawksmountainranch.com/HMRscrapiefacts.html
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| | [No title] |
| | DESCRIPTORS: bovine spongiform encephalopathy (BSE), salmonellosis, listeria, scrapie, somatotropin, legislation, human health, zoonoses. | | | Scrapie and other forms of spongiform encephalopathy are present in the United States, hence, the intense interest in BSE. | | | 014 "Scrapie agent in muscle." (Correspondence) I. Pattison. |
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http://netvet.wustl.edu/species/cows/srb91-05.txt
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| | Rural NI Livestock Sheep Technical information Technical note 2 |
| | You may see the signs of scrapie at any time of the year but stress such as lambing can increase the development of symptoms. | | | Scrapie is confirmed after death of the animal by examining its brain tissue. | | | You cannot test for scrapie until the disease is well developed. |
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http://www.ruralni.gov.uk/livestock/sheep/technical_information/note2.htm
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| | MedlinePlus Medical Encyclopedia: Creutzfeldt-Jakob disease |
| | Additional symptoms that may be associated with this disease: | | | Creutzfeldt-Jakob disease may be related to several other diseases also thought to be caused by prions, including kuru (seen in New Guinea women who ate the brains of deceased relatives as part of a funerary ritual), scrapie (found in sheep), and other rare human diseases, such as Gerstmann-Straussler-Scheinker disease and fatal familial insomnia. |
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http://www.nlm.nih.gov/medlineplus/ency/article/000788.htm
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| | Sheep - Scrapie |
| | Currently there is no cure for scrapie, sheep that get the disease always die. | | | Scrapie is a disease of sheep and goats that destroys their brains. | | | When they first get scrapie it is often difficult to tell if they have the disease. |
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http://www.colostate.edu/Depts/CoopExt/Adams/ag/scrapie.htm
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| | Scrapie |
| | Creutzfeldt-Jacob Disease (CJD) and the new variant (nv) CJD are the two most publicized TSE's of man. Chronic Wasting Disease (CWD) affects wild deer and elk. | | | · The current view is that clinical scrapie results from the interaction of one or more stains of the infectious agent with one or more host genetic factors. | | | Scrapie belongs to a group of similar diseases known as transmissible spongiform encephalopathies (TSE). |
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http://www.dlab.colostate.edu/webdocs/ext_vet/cleon6.html
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| | Scrapie Interactive |
| | Joining Scrapie is a great opportunity to buff up your CV and also do something which you may have never considered doing before. | | | Scrapie runs a training residential in the Yorkshire dales for all its members, which basically include team building games and working out what Scrapie is doing for the year. | | | Scrapie is run by the exec but all the hard work and dedication comes from its members. |
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http://scrapie.datasnake.co.uk/index.xml
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| | Scrapie |
| | Scrapie is an old disease, recognized in sheep and goats for more than 250 years. | | | The word "prion" was coined at that time by Dr. Stanley Prusiner to indicate that this disease was caused by a "proteinaceous infectious agent." The protein that causes this and all other prion diseases is called PrPSC, which stands for prion protein of scrapie (2). | | | In 1982, it was first identified as a prion disease. |
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http://science-education.nih.gov/nihHTML/ose/snapshots/multimedia/ritn/prions/scrapie.html
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| | Maryland Small Ruminant Page - Scrapie |
| | Scrapie Study Estimates Prevalencein National SheepFlock - USDA APHIS | | | BSE and Scrapie: the search for diagnostic tests | | | Scrapie FAQ's - Minnesota Board of Animal Health |
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http://www.sheepandgoat.com/scrapie.html
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| | Defra, UK - Animal health & welfare - BSE - Other TSEs - Scrapie - NSP |
| | Defra, UK - Animal health and welfare - BSE - Other TSEs - Scrapie - NSP | | | The National Scrapie Plan (NSP) for Great Britain is a strategic long-term plan which consists of a breeding programme to increase the number of sheep that genetically are naturally resistant to Transmissible Spongiform Encephalopathies (TSEs) eg scrapie. | | | Information regarding appeals against non inclusion has also been published and sets out the criteria the Semen Archive Management Board will have regard to in considering appeals against non inclusion from a Breed Society. |
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http://www.defra.gov.uk/nsp
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| | Scrapie |
| | Scrapie is not widespread in the United States sheep population, however, there is a need for Michigan producers to assume a proactive stance on the Scrapie issue. | | | Browsers that can not handle javascript will not be able to access some features of this site. | | | • Handling of Scrapie suspect and Scrapie positive animals |
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http://www.michigan.gov/mda/0,1607,7-125-1567_1601_7094---,00.html
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| | Scrapie Flock Certification Program - Flock Status Report by State |
| | Participation in the Voluntary Scrapie Flock Certification Program provides a means for producers to certify the status of their flocks in regard to scrapie. | | | If you have a question or concern regarding the list or the USDA scrapie program please contact your local USDA Area Office, or one of the individuals listed at the bottom of the report. | | | This list is also electronically published organized by breed and certified flocks. |
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http://scrapietag.aphis.usda.gov/reports/sisstate.php
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| | Scrapie |
| | Description: Scrapie is a slow, transmissible disease affecting the central nervous system of sheep and goats. | | | Affected animals rub or scrape themselves to relieve itching. |
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http://www.oznet.ksu.edu/library/lvstk2/samplers/mf968.asp
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| | Official Mad Cow Disease Home Page |
| | Note: news, policy, commentar, medicine have moved to new site | | | 7,431+ articles on mad cow disease, Creutzfeldt-Jacob Disease, prions, spongiform encephalopathies, scrapie, BSE, CJD, CWD, TME, and TSE | | | 7,651+ articles on mad cow disease, Creutzfeldt-Jakob Disease, VCJD, nvCJD, prions, spongiform encephalopathies, scrapie, BSE, CJD, CWD, TME, and TSE |
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http://www.mad-cow.org
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| | Canola Oil |
| | material from dead sheep, and sheep suffer from a disease called "scrapie". | | | It was thought this was how "Mad Cow" began and started to infiltrate the human | | | Cattle were being fed on a mixture containing |
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http://www.ithyroid.com/canola_oil.htm
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