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| | Severe acute respiratory syndrome - Wikipedia, the free encyclopedia |
 | | A chest x-ray showing increased opacity in both lungs, indicative of pneumonia, in a patient with SARS. | | | Following their experience with SARS, the Canadians have put together an excellent exposition of the ethical principles that apply in an epidemic or pandemic, and discussion of how the were/can be applied in practice. | | | WHO set up a network for doctors and researchers dealing with SARS, consisting of a secure web site to study chest x-rays and a teleconference. |
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http://en.wikipedia.org/wiki/SARS
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| | (D2OL)™ - Pathogens - SARS |
| | Because we knew that all coronaviruses are very similar to each other, we made the basic assumption that since the 3CL-PRO was so essential for the coronavirus to work properly that the 3CL-PRO structure was likely to be very similar if not identical among all members of the coronavirus family. | | | The third target for this study is the 3CL-PRO from the HCo-V human coronavirus. | | | As per our assumption, the guts of the 3CL-PRO (the parts that make it work correctly) are the similar enough across all coronaviruses such that drugs that are useful for one type should be useful for all |
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http://www.d2ol.com/SARS.html
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| | SARS: An Open Scar Virus > Novel Coronavirus |
| | There has been speculation that the novel coronavirus originated from palm civets, a cat-like mammal closely related to the mongoose, in Guangdong (China). | | | Anand, K., etc. Coronavirus Main Proteinese (3Clopro) Structure: Basis for Design of Anti-SARS Drugs. | | | At anytime you can return to this list by clicking on 'Content Outline' at the end of each part. |
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http://www.openscar.com/novelcov.html
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| | CIDRAP >> NIAID offers genome of SARS virus on chip |
| | Determining which virus strains are most dangerous and gathering information for development of antiviral drugs by comparing clinical outcomes among people infected with different viral strains | | | In the announcement, NIAID Director Anthony S. Fauci, MD, said, "This powerful tool will help us better understand this newly recognized pathogen and its spread, and will provide new leads in our search for effective SARS countermeasures." | | | The distribution program is part of an ongoing effort by NIAID to promote the use of genomics to improve the understanding of pathogenic microbes and the development of diagnostics and other medical tools for them. |
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http://www.cidrap.umn.edu/cidrap/content/hot/sars/news/june2303chip.html
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| | Coronaviruses |
| | There is considerable experience of development of coronavirus vaccines for veterinary purposes – though not all of it is encouraging. | | | Studies indicate that this worsening may be related to patient's immune responses rather than uncontrolled viral replication. | | | (2005) Evidence of a novel human coronavirus that is associated with respiratory tract disease in infants and young children. |
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http://www-micro.msb.le.ac.uk/3035/Coronaviruses.html
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| | NEJM -- SARS-Associated Coronavirus |
| | of a human coronavirus that acquired new virulence factors, | | | The deaths of 3 to 4 percent of patients with SARS | | | coronavirus in fecal and serum samples from patients, as well |
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http://content.nejm.org/cgi/content/full/348/20/1948
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| | WHO Coronavirus never before seen in humans is the cause of SARS |
| | The 13 laboratories have been working on meeting Koch’s postulates, necessary to prove disease causation. | | | GENEVA -- Today, the World Health Organization announced that a new pathogen, a member of the coronavirus family never before seen in humans, is the cause of Severe Acute Respiratory Syndrome (SARS). | | | Coronavirus never before seen in humans is the cause of SARS |
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http://www.who.int/mediacentre/releases/2003/pr31/en
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| | SARS Coronavirus Resource |
| | Coronavirus Main Proteinase (3CLpro) Structure: Basis for Design of Anti-SARS Drugs | | | The WHO coined the disease as "severe acute respiratory syndrome", or SARS. | | | In April 2003, a previously unknown coronavirus was isolated from patients and subsequenly proven to be the causative agent according to Koch's postulates in experiments on monkeys. |
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http://www.ncbi.nlm.nih.gov/genomes/SARS/SARS.html
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| | SARS: An Open Scar |
| | The world is still on alert and the search for a cure continues. | | | Untill today, no real cure has been discovered. | | | SARS had left an unmistakable scar on the medical history. |
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http://www.openscar.com
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| | CIDRAP >> Severe Acute Respiratory Syndrome |
| | Two-year prospective study of the humoral immune response of patients with SARS | | | Scoring system estimates a patient's risk for SARS | | | Nasopharyngeal shedding of severe acute respiratory syndrome-associated coronavirus is associated with genetic polymorphisms |
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http://www.cidrap.umn.edu/cidrap/content/hot/sars
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| | SARS - Hutchinson encyclopedia article about SARS |
| | SARS is caused by a type of coronavirus, which usually produces colds in humans but severe conditions such as pneumonia and diarrhoea in animals. | | | First identified in 2003, there is no known cure or vaccine for the disease. | | | The disease was identified and named by Carlo Urbani, an infectious disease expert working for the WHO in Bangkok, Thailand, who was called to Hanoi, Vietnam, in February 2003 to examine a US industrialist suffering from an unidentified illness. |
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http://encyclopedia.farlex.com/SARS
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| | SARS Bioinformatics Suite |
| | Explanation of Orf1ab Frameshift and Pseudoknot RNA structure | | | The woman, a medical doctor, was the mother of a 26-year-old postgraduate student who had been conducting research at the National Institute of Virology in Beijing. | | | The 3' s2m motif (stem-loop II-like motif) in SARS and other coronaviruses |
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http://athena.bioc.uvic.ca/sars
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| | Coronavirus SARS |
| | A member of the Coronavirus family is considered to cause the Severe Acute Respiratory Syndrome (SARS). | | | A part of a putative Coronavirus polymerase gene was identified via PCR in a SARS patient by the Bernhard Nocht Institute for Tropical Medicine in Hamburg and cooperating laboratories. | | | In the literature its suggested name is Human Pneumonia-Associated Coronavirus (HPAC). |
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http://www.gentaur.com/sars_detection.htm
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| | BBC NEWS Health Fresh doubt cast on Sars cause |
| | Many experts believe it will be some years before an effective vaccine for this new strain of coronavirus is available. | | | The World Health Organization says it is reasonably certain that Sars is caused by infection with a new strain of coronavirus. | | | The virus pinpointed as the likely cause of the killer Sars illness may not be responsible - most Canadian victims don't carry it. |
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http://news.bbc.co.uk/1/hi/health/2970075.stm
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| | CBC News: Scientists confirm identity of SARS virus |
| | The researchers identified the virus by looking at clinical and post-mortem samples from 436 SARS patients in six countries. | | | "Collectively, these results of laboratory studies of SARS patients and experimental infections of macaques prove that the newly discovered SARS-CoV is the primary causal agent of SARS," said the study's lead author, virology Prof. | | | For months, scientists have believed it was behind severe acute respiratory syndrome, which has been responsible for 41 deaths in the Toronto area. |
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http://www.cbc.ca/stories/2003/07/21/sars030721
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| | NEJM: Articles on severe acute respiratory syndrome |
| | Coronavirus Genomic-Sequence Variations and the Epidemiology of the Severe Acute Respiratory Syndrome | | | The SARS collection covers topics such as the epidemiology and clinical manifestations of the severe acute respiratory syndrome, the radiological manifestations, identification of the coronavirus, and includes research articles, case reports, letters, and editorial commentary. | | | Tsui S. K.W., Chim S. S.C., Lo Y.M. D., the Chinese University of Hong Kong (CUHK) Molecular SARS Research Group |
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http://content.nejm.org/cgi/collection/sars
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| | A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus−induced lung injury - Nature Medicine |
| | These results provide a molecular explanation why SARS-CoV infections cause severe and often lethal lung failure and suggest a rational therapy for SARS and possibly other respiratory disease viruses. | | | During several months of 2003, a newly identified illness termed severe acute respiratory syndrome (SARS) spread rapidly through the world | | | A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus−induced lung injury - Nature Medicine |
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http://www.nature.com/nm/journal/v11/n8/abs/nm1267.html
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| | CDC SARS-Associated Coronavirus (SARS-CoV) Sequencing |
| | Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory Syndrome | | | The accession number for the sequence of SARS-CoV (Urbani strain) is AY278741. | | | On April 14, 2003, the Centers for Disease Control and Prevention (CDC) announced the completion of the full-length genetic sequencing of the genome of the SARS-associated coronavirus (SARS-CoV). |
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http://www.cdc.gov/ncidod/sars/sequence.htm
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| | UniProtKB/Swiss-Prot headline |
| | The SARS coronavirus is a new human pathogen that emerged in Asia in 2002-2003. | | | The severity of the 2002-2003 epidemic was presumably due to those two amino-acid mutations, giving opportunity to an animal virus to cause a major infection in the human species. | | | We have made a first annotation run of the proteins potentially encoded by the SARS (Severe Acute Respiratory Syndrome) coronavirus. |
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http://www.expasy.org/sprot/relnotes/spwrnew.html
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