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| | Comparison of Rosiglitazone and Metformin for Treating HIV Lipodystrophy: results suggest improvements in lipoatrophy ... |
 | | Whether the outcomes are similar with long-term rosiglitazone therapy remains to be shown. | | | In our study, the patients receiving stavudine therapy did not show an increase in subcutaneous adipose tissue with rosiglitazone, which may explain the lack of efficacy in previous studies that had a baseline imbalance and overuse of stavudine in the rosiglitazone group (18, 19). | | | Comparison of Rosiglitazone and Metformin for Treating HIV Lipodystrophy: results suggest improvements in lipoatrophy associated with rosiglitazone. |
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http://www.natap.org/2005/HIV/090605_04.htm
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| | MedlinePlus Drug Information: Rosiglitazone (Systemic) |
| | Other medicines—Do not take other medicines during the time you are taking rosiglitazone unless they have been discussed with your doctor. | | | Children—Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of rosiglitazone in children with use in other age groups. | | | When you are taking rosiglitazone, it is especially important that your doctor and pharmacist know if you are taking any of the following: |
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http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/500022.html
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| | EHS: Mosby's Drug Consult - Drug Updates - Rosiglitazone Maleate and Metformin Hydrochloride 003571 |
| | The following recommendations regarding the use of Avandamet in patients inadequately controlled on rosiglitazone and metformin monotherapies are based on clinical practice experience with rosiglitazone and metformin combination therapy. | | | Additional efficacy and safety information about rosiglitazone and metformin monotherapies may be found in the prescribing information for each individual drug. | | | In rosiglitazone and metformin combination studies, efficacy was demonstrated with no gender differences in glycemic response. |
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http://www.mosbysdrugconsult.com/DrugConsult/003571.html
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| | rosiglitazone news articles |
| | Rosiglitazone (Avandia), troglitazone (Rezulin), and pioglitazone (ACTOS) are part of a group of medications called thiazolidinediones. | | | Rosiglitazone, marketed as Avandia, was given to test subjects for 12 weeks without changing their current medications. | | | These include switching anti-HIV drugs and the use of drugs such as rosiglitazone and metformin to directly treat body fat changes. |
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http://www.mongabay.com/drugs/drugs/rosiglitazone.html
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| | MedlinePlus Drug Information: Rosiglitazone |
| | You will have these tests before you begin to take rosiglitazone, and then every 2 months for the first year of therapy. | | | tell your doctor and pharmacist if you are allergic to rosiglitazone, pioglitazone, troglitazone, or any other drugs. | | | Your blood sugar and glycosolated hemoglobin (HbA1c) should be checked regularly to determine your response to rosiglitazone. |
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http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a699023.html
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| | Aidsmap Rosiglitazone causes lipomas in HIV-positive man with fat loss |
| | The investigators recommend that rosiglitazone “therapy should be approached with caution in patients with HIV-associated lipoatrophy.” | | | However one randomised study found no effect of rosiglitazone on peripheral fat loss. | | | Development of multiple lipomas during treatment with rosiglitazone in a patient with HIV-associated lipoatrophy. |
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http://www.aidsmap.com/en/news/BFCBC4E1-FC92-486A-9E95-68EADEE2D66E.asp
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| | Rosiglitazone for ulcerative colitis study Q & A |
| | As a result, the only way to determine if rosiglitazone will help treat ulcerative colitis is to conduct a study such as this. | | | In our preliminary studies in humans with ulcerative colitis that had not responded to any other therapy, more than half of the patients had improved symptoms within 12 weeks after starting treatment with rosiglitazone. | | | In several studies, animals treated with rosiglitazone recovered more quickly from experimental colitis than those that were not treated with rosiglitazone. |
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http://www.rucstudy.org/qa.html
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| | Diabetes Monitor - rosiglitazone (Avandia) |
| | Three of the 10 patients who developed cardiac failure had no known prior evidence of CHF or preexisting cardiac condition. | | | Avandia (rosiglitazone) is a thiazolidinedione medication for the therapy of | | | The use of Avandia (rosiglitazone maleate) in combination therapy with insulin is also indicated. |
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http://www.diabetesmonitor.com/avandia.htm
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| | Rosiglitazone |
| | If you have an allergy to rosiglitazone or any other part of the medicine. | | | If you have active liver disease or yellowing (jaundice) during troglitazone therapy. |
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http://www.umm.edu/altmed/ConsDrugs/Rosiglitazonecd.html
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| | EASD: Rosiglitazone Works By Reducing Insulin Resistance |
| | After 26 weeks, the combination of sulphonylurea and rosiglitazone led to an increase in function of 63 percent, compared with sulphonylurea therapy and placebo. | | | Data was pooled from three multicentre, double-blind studies of rosiglitazone as monotherapy in 2,090 patients. | | | Investigators compared rosiglitazone with a sulphonylurea (a traditional oral anti-diabetes medicine) in 231 patients previously treated with diet and exercise alone. |
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http://www.pslgroup.com/dg/132FFA.htm
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| | News - Gemfibrozil Increases Plasma Concentrations of Rosiglitazone |
| | Considerable variability between individuals in the extent of drug interaction was noted, with the relative increase in rosiglitazone concentration ranged from 51 to 179%. | | | The researchers recommend that rosiglitazone dose be reduced by about 50 to 70% if gemfibrozil treatment is started on a patient using rosiglitazone, and the patient carefully monitored for signs and symptoms of adverse effects. | | | Administration of usual therapeutic doses of gemfibrozil considerably increases the plasma concentrations of rosiglitazone, an insulin-sensitising drug used to treat patients with Type 2 diabetes mellitus. |
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http://docguide.com/news/content.nsf/news/8525697700573E1885256D7A002EBB4A
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| | FDA Approves Rosiglitazone to Treat Type II Diabetes |
| | In clinical studies of patients treated with rosiglitazone, by contrast, there was no evidence of drug-induced hepatotoxicity. | | | In general, rosiglitazone was well-tolerated in clinical studies. | | | In clinical trials, involving more than 4000 patients previously treated with diet alone or with metformin, rosiglitizone was shown to improve patients' ability to utilize insulin produced in the body. |
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http://www.fda.gov/bbs/topics/ANSWERS/ANS00957.html
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| | Fact Sheets > Drugs and Medications > Avandia or Rosiglitazone |
| | Be sure to consult your doctor before making any major medical decision. | | | Fact Sheets > Drugs and Medications > Avandia or Rosiglitazone | | | Avandia, in addition to diet and exercise, improves blood sugar control in adults with type 2 (non-insulin-dependent) diabetes. |
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http://www.fact-sheets.com/health/drugs-medications/avandia
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| | Patient Education - Rosiglitazone (Avandia) |
| | There have been no problems with interactions with other medicines. | | | Your medical provider has prescribed Rosiglitazone to treat your diabetes. | | | Most people experience no side effects from Rosiglitazone. |
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http://www.alaska.net/~akdm/Clinical/patient_ed/rosiglit_pat_ed.htm
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| | News - Rosiglitazone Could Have Antiinflammatory Effects |
| | "These observations may have implications for long-term atherogenesis in subjects treated with rosiglitazone and possibly with other thizolidinediones," they add. | | | After 6 weeks of rosiglitazone therapy, plasma TNF-á and SAA were significantly inhibited in obese nondiabetic subjects but not in obese diabetic patients. | | | Eight obese nondiabetic subjects and 5 obese diabetic patients who did not receive rosiglitazone treatment were included as controls. |
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http://www.docguide.com/news/content.nsf/news/8525697700573E1885256EAE00241B60
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| | Rosiglitazone, Avandia at PharmacyWanted.com |
| | Continue to take rosiglitazone and talk to your doctor if you experience: | | | These may be early symptoms of heart problems. | | | Rosiglitazone may also be used with a sulfonylurea (e.g., Diabeta, Glucotrol, Micronase, others), metformin (Glucophage), or insulin when diet and exercise plus any one of these medicines alone do not result in adequate blood sugar control. |
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http://www.pharmacywanted.com/rosiglitazone-avandia.php
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| | Avandia and Avandamet type 2 diabetes medication |
| | Very rarely, some patients have experienced vision changes due to swelling in the back of the eye while taking rosiglitazone, a component of Avandaryl. | | | If you experience an unusually rapid increase in weight, swelling, shortness of breath, or have a history of these conditions, talk to your doctor immediately. | | | In combination with insulin rosiglitazone, one of the components of Avandaryl, may increase the risk of other heart problems. |
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http://www.avandia.com
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| | Avandia - Drugs & Vitamins - Drug Library - DrugDigest |
| | Check with your health care professional before stopping or starting any of your medicines. | | | Check with your prescriber or health care professional if your blood sugar is high, you may need a change of dose of rosiglitazone. | | | If you are going to have surgery, tell your prescriber or health care professional that you are taking rosiglitazone. |
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http://www.drugdigest.org/DD/DVH/Uses/0,3915,732Avandia,00.html
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| | Rosiglitazone Significantly Increases Triglyceride and Cholesterol Levels and Does Not Improve HAART-associated ... |
| | Rosiglitazone in the treatment of HAART-associated lipodystrophy--a randomized double-blind placebo-controlled study. | | | There are no controlled studies of glitazones in patients with HAART-associated lipodystrophy (HAL). | | | The authors conclude, “Contrary to data in other patient groups, rosiglitazone did not increase subcutaneous fat in patients with HAL after 24 weeks of treatment. |
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http://www.hivandhepatitis.com/recent/metabolic/dyslipidemias/082903b.html
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| | ROSIGLITAZONE |
| | Some drugs taken together may have interactions that cause illness or impair the effectiveness of the drugs. | | | It is a good idea to always check with your study clinician before taking any other medications, prescription or otherwise, to be sure it will not interact with rosiglitazone. | | | Rosiglitazone is a medication that is commonly used to help control blood sugar in people with diabetes. |
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http://depts.washington.edu/actu/drugs/rosiglitazone.htm
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| | GlaxoSmithKline Clinical Trial Register - Rosiglitazone Studies |
| | A multi-center, open-label extension study to assess the safety and efficacy of rosiglitazone as monotherapy or in combination with concurrent metformin or sulphonylurea therapy when administered to patients with type 2 diabetes. | | | A post-marketing surveillance study of Avandia (Rosiglitazone) in the treatment of Filipino patients with type 2 diabetes | | | A multi-center, open-label study to assess the safety and efficacy of rosiglitazone (RSG) as monotherapy or in combination therapy with concurrent Metformin (Met) or Sulphonylurea (SU) when administered to Chinese patients with Type 2 diabetes. |
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http://ctr.gsk.co.uk/Summary/Rosiglitazone/StudyList.asp
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| | Rosiglitazone, a Peroxisome Proliferator-Activated Receptor-Gamma, Inhibits the Jun NH(2)-Terminal Kinase/Activating ... |
| | This study was conducted to evaluate whether treatment of normal and diabetic rat hearts with rosiglitazone, a high-affinity ligand of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) used for the treatment of type 2 diabetes, improves postischemic functional recovery. | | | A Comparison of the Effects of Rosiglitazone and Glyburide on Cardiovascular Function and Glycemic Control in Patients With Type 2 Diabetes | | | In a chronic protocol in which rosiglitazone was given by daily gavage (10 micromol/kg body wt) immediately after STZ injection, rosiglitazone also prevented postischemic injury and significantly improved functional recovery. |
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http://www.ndei.org/v2/website/litalerts/article.cfm?article_id=505
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| | New Data Show Avandia(R) (rosiglitazone maleate) May Reduce Blood Pressure, an Important Cardiovascular Risk Factor, in ... |
| | According to the American Heart Association, patients with type 2 diabetes are two to four times more likely to develop cardiovascular disease. | | | New Data Show Avandia(R) (rosiglitazone maleate) May Reduce Blood Pressure, an Important Cardiovascular Risk Factor, in Type 2 Diabetes Patients - Forbes.com | | | New Data Show Avandia(R) (rosiglitazone maleate) May Reduce Blood Pressure, an Important Cardiovascular Risk Factor, in Type 2 Diabetes Patients |
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http://www.forbes.com/prnewswire/feeds/prnewswire/2005/06/11/prnewswire200506111300PR_NEWS_B_MAT_NY_NYSA001.html
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| | 79 - Abstract (11th CROI) |
| | Rosiglitazone for the Treatment of HIV Lipoatrophy: A Double-blind, Placebo-controlled, 48-week Trial | | | Conclusions: RSG 4 mg bid for 48 weeks did not improve lipoatrophy in HIV-infected adults receiving antiretroviral therapy, despite significantly improving insulin sensitivity and plasma adiponectin levels. | | | Thiazolidinediones such as rosiglitazone (RSG) promote subcutaneous fat growth, decrease visceral fat, and improve glycemic and lipid parameters in type 2 diabetics and in adults with congenital LD, and reverse protease inhibitor (PI) toxicity to adipocytes in vitro. |
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http://www.retroconference.org/2004/cd/Abstract/79.htm
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| | Resistin and Type 2 Diabetes: Regulation of Resistin Expression by Insulin and Rosiglitazone and the Effects of ... |
| | Resistin and Type 2 Diabetes: Regulation of Resistin Expression by Insulin and Rosiglitazone and the Effects of Recombinant Resistin on Lipid and Glucose Metabolism in Human Differentiated Adipocytes -- McTernan et al. | | | determine the in vitro effects of insulin and rosiglitazone | | | Resistin and Type 2 Diabetes: Regulation of Resistin Expression by Insulin and Rosiglitazone and the Effects of Recombinant Resistin on Lipid and Glucose Metabolism in Human Differentiated Adipocytes |
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http://jcem.endojournals.org/cgi/content/full/88/12/6098
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