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Topic: Reverse transcriptase

Ads by Google      Reverse Transcriptase RT sequence alignment used in our analysis of clinical HIV-1 isolates [supplement to Wrobel et al. Click here to view more interactive Reverse Transcriptase images View HIV-1 and MMLV Reverse Transcriptase structures (requires Chime plug-in) http://www.unc.edu/~wrobel/rt.html   (421 words)      Nucleoside reverse transcriptase inhibitors impair endothelium-dependent relaxation by increasing superoxide -- Sutliff ... Nucleoside reverse transcriptase inhibitor (NRTI) treatment reduced endothelium-dependent relaxation but not endothelium-independent relaxation of mouse aorta. Nucleoside reverse transcriptase inhibitors impair endothelium-dependent relaxation by increasing superoxide Nucleoside reverse transcriptase inhibitors impair endothelium-dependent relaxation by increasing superoxide -- Sutliff et al. http://ajpheart.physiology.org/cgi/content/full/283/6/H2363   (3709 words)      Influence of Reverse Transcriptase Variants, Drugs, and Vpr on Human Immunodeficiency Virus Type 1 Mutant Frequencies ... Resistance profile of the human immunodeficiency virus type 1 reverse transcriptase inhibitor abacavir (1592U89) after monotherapy and combination therapy. Isolation and characterization of a dideoxyguanosine triphosphate-resistant mutant of human immunodeficiency virus reverse transcriptase. The K65R mutant reverse transcriptase of HIV-1 cross-resistant to 2', 3'-dideoxycytidine, 2',3'-dideoxy-3'-thiacytidine, and 2',3'-dideoxyinosine shows reduced sensitivity to specific dideoxynucleoside triphosphate inhibitors in vitro. http://jvi.asm.org/cgi/content/full/77/3/2071   (6500 words)      Truvada To learn more about how this once-a-day HIV treatment is used, click here. Truvada is an anti-HIV drug in the nucleoside reverse transcriptase inhibitor (NRTI or "nuke") family and is always given in combination with other anti-HIV drugs. http://www.truvada.com   (391 words)      Notice to Readers: Updated Guidelines for the Use of Rifamycins for the Treatment of Tuberculosis Among HIV-Infected ... Prevention and treatment of tuberculosis among patients infected with human immunodeficiency virus: principles of therapy and revised recommendations. Updated guidelines for the use of rifabutin or rifampin for the treatment and prevention of tuberculosis among HIV-infected patients taking protease inhibitors or nonnucleoside reverse transcriptase inhibitors. Guidelines for managing the pharmacologic interactions that can result when patients receive protease inhibitors (PIs) and nonnucleoside reverse transcriptase inhibitors (NNRTIs) for treatment of human immunodeficiency virus (HIV) infection together with rifamycins for the treatment of tuberculosis have been published previously (1,2). http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5302a6.htm   (413 words)      A 6-Basepair Insert in the Reverse Transcriptase Gene of Human Immunodeficiency Virus Type 1 Confers Resistance to ... Chesebro, and T.C. Merigan (1996) Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy. Relationship between patients' reverse transcriptase inhibitor treatment history and the appearance of insert-containing HIV-1 strains. Darby, and D.D. Richman (1989) HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy. http://www.jci.org/cgi/content/full/102/10/1769   (5877 words)      APHS can act synergically with clinically available HIV-1 reverse transcriptase and protease inhibitors and is active ... therapy uses two classes of drugs: reverse transcriptase (RT) A randomized, controlled, double-blind study comparing the survival benefit of four different reverse transcriptase inhibitor therapies (three-drug, two-drug, and alternating drug) for the treatment of advanced AIDS. Tavel, J. A., Miller, K. and Masur, H. Guide to major clinical trials of antiretroviral therapy in human immunodeficiency virus-infected patients: protease inhibitors, non-nucleoside reverse transcriptase inhibitors, and nucleotide reverse transcriptase inhibitors. http://jac.oupjournals.org/cgi/content/full/51/5/1181   (4627 words)      Detection of Mycobacterium tuberculosis Group Organisms in Human and Mouse Joint Tissue by Reverse Transcriptase PCR: ... Previous studies from our laboratory using reverse transcriptase Synovial tissue RNAs of patients from cohorts 1 and 2 were reverse transcribed and subjected to analysis for bacteria and Detection of Mycobacterium tuberculosis Group Organisms in Human and Mouse Joint Tissue by Reverse Transcriptase PCR: Prevalence in Diseased Synovial Tissue Suggests Lack of Specific Association with Rheumatoid Arthritis -- Kempsell et al. http://iai.asm.org/cgi/content/full/69/3/1821   (5692 words)      Clinical efficacy of antiretroviral combination therapy based on protease inhibitors or non-nucleoside analogue reverse ... Table 1 Characteristics of 14 randomised controlled trials comparing protease inhibitor based triple therapy and non-nucleoside analogue reverse transcriptase inhibitor (NNRTI) based triple regimens with dual therapy Adherence to highly active antiretroviral therapy is better in patients receiving non-nucleoside reverse transcriptase inhibitor-containing regimens than in those receiving protease inhibitor-containing regimens. A randomized, controlled, double-blind study comparing the survival benefit of four different reverse transcriptase inhibitor therapies (three-drug, two-drug, and alternating drug) for the treatment of advanced AIDS. http://bmj.com/cgi/content/full/328/7434/249   (4060 words)      Reverse Transcriptase Activity in Mature Spermatozoa of Mouse -- Giordano et al. 148 (6): 1107 -- The Journal of Cell ... A growing body of evidence supports the notion that spermatozoa CNR Center for the Study of Germinal Cells, University of Siena, 53100 Italy We show here that a reverse transcriptase (RT) activity is present http://www.jcb.org/cgi/content/full/148/6/1107   (3643 words)      Reverse transcriptase - Wikipedia, the free encyclopedia Reverse transcriptase is commonly used in research to apply the polymerase chain reaction technique to RNA. The classical PCR technique can only be applied to DNA strands, but with the help of reverse transcriptase, RNA can be transcribed into DNA, thus making PCR analysis of RNA molecules possible. The technique is collectively called Reverse Transcription-Polymerase Chain Reaction (RT-PCR). http://www.wikipedia.org/wiki/Reverse_transcriptase   (516 words)      Emtricitabine: A Once-Daily Nucleoside Reverse Transcriptase Inhibitor -- Modrzejewski and Herman 38 (6): 1006 -- The ... Key Words: antiretroviral therapy, emtricitabine, HIV, nucleoside reverse transcriptase inhibitor Emtricitabine: A Once-Daily Nucleoside Reverse Transcriptase Inhibitor -- Modrzejewski and Herman 38 (6): 1006 -- The Annals of Pharmacotherapy Articles by Modrzejewski, K. Articles by Herman, R. Emtricitabine: A Once-Daily Nucleoside Reverse Transcriptase Inhibitor http://www.theannals.com/cgi/content/abstract/38/6/1006   (260 words)      Genotypic Correlates of Phenotypic Resistance to Efavirenz in Virus Isolates from Patients Failing Nonnucleoside ... Genotypic Correlates of Phenotypic Resistance to Efavirenz in Virus Isolates from Patients Failing Nonnucleoside Reverse Transcriptase Inhibitor Therapy Comparison of Four-Drug Regimens and Pairs of Sequential Three-Drug Regimens as Initial Therapy for HIV-1 Infection. Genotypic Correlates of Phenotypic Resistance to Efavirenz in Virus Isolates from Patients Failing Nonnucleoside Reverse Transcriptase Inhibitor Therapy -- Bacheler et al. http://dx.doi.org/10.1128/JVI.75.11.4999-5008.2001   (630 words)      Welcome to Emtriva.com - The online resource for Emtriva (emtricitabine) Should you have any questions concerning the revised Prescribing Information, please contact the Gilead Medical Information Department at 1-800-GILEAD-5 (1-800-445-3235). (emtricitabine) — the second antiretroviral agent for the treatment of HIV-1 infection available from Gilead Sciences — is a one capsule, once-daily nucleoside reverse transcriptase inhibitor for use in combination with other antiretroviral drugs. This Web site is designed to help you learn more about Emtriva. http://www.emtriva.com   (331 words)      A Conserved Telomerase Motif within the Catalytic Domain of Telomerase Reverse Transcriptase Is Specifically Required ... Reverse transcriptase motifs in the catalytic subunit of telomerase. Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility. Analysis of telomerase processivity: mechanistic similarity to HIV-1 reverse transcriptase and role in telomere maintenance. http://mcb.asm.org/cgi/content/full/23/23/8440   (5768 words)      Laser Capture Microdissection and Real-Time Reverse Transcriptase/ Polymerase Chain Reaction of Bronchiolar Epithelium ... Division of Pulmonary and Critical Care Medicine, Department of Medicine; and Laboratory Medicine, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri from whole lungs was reverse transcribed in a total volume 20 Laser Capture Microdissection and Real-Time Reverse Transcriptase/ Polymerase Chain Reaction of Bronchiolar Epithelium after Bleomycin -- Betsuyaku et al. http://ajrcmb.atsjournals.org/cgi/content/full/25/3/278   (3982 words)      Evidence for Copurification of HERV-K-Related Transcripts and a Reverse Transcriptase Activity in Human Platelets From ... Evidence for Copurification of HERV-K-Related Transcripts and a Reverse Transcriptase Activity in Human Platelets From Patients With Essential Thrombocythemia Mwenda JM: Biochemical characterization of a reverse transcriptase activity associated with retroviral-like particles isolated from human placental villous tissue. Evidence for Copurification of HERV-K-Related Transcripts and a Reverse Transcriptase Activity in Human Platelets From Patients With Essential Thrombocythemia -- Boyd et al. http://www.bloodjournal.org/cgi/content/full/90/10/4022   (6530 words)      7th Conference - Abstract 81 The effect of TPV on the pharmacokinetics of nucleoside reverse transcriptase inhibitors (NRTIs) was investigated in a Phase I/II study in HIV-1 infected patients. The Pharmacokinetics of Nucleoside Reverse Transcriptase Inhibitors when Coadministered with the HIV Protease Inhibitor Tipranavir in HIV-1 Infected Patients Methods: Patients on stable dual NRTIs for >2 months were randomized to one of 3 TPV dose groups: 900, 1200, or 1500 mg three times daily, administered as 150-mg hard-filled capsules. http://www.retroconference.org/2000/abstracts/81.htm   (341 words)      Abstract 13 - TMC120, a New Non- Nucleoside Reverse Transcriptase Inhibitor, Is a Potent Antiretroviral in Treatment ... Abstract 13 - TMC120, a New Non- Nucleoside Reverse Transcriptase Inhibitor, Is a Potent Antiretroviral in Treatment Naive, HIV-1 Infected Subjects. 13 TMC120, a New Non- Nucleoside Reverse Transcriptase Inhibitor, Is a Potent Antiretroviral in Treatment Naive, HIV-1 Infected Subjects. Background:TMC120 (R147681), a dianilinopyrimidine (DAPY) derivative, is a novel, non-nucleoside reverse transcriptase inhibitor (NNRTI) with equipotent in vitro activity (IC = 1-10 nM) against wild-type HIV-1 and NNRTI-resistant variants encoding K103N, Y181C or G190A/S mutations. http://www.retroconference.org/2001/abstracts/abstracts/abstracts/13.htm   (243 words)      John Wrobel Crystal Structure of the 66 kD subunit of the HIV-1 Reverse Transcriptase Besides providing a better understanding of the HIV-1 reverse transcriptase in particular, this project demonstrated the utility of saturation mutagenesis to study the function and stability of proteins in general, especially for proteins for which no structural data are available. Evalutated amino-acid substitutions in the reverse transcriptase of clinical HIV-1 isolates using phenotype data from a collection of HIV-1 reverse transcriptase mutants. http://www.unc.edu/%7Ewrobel   (1151 words)      Inhibition of HIV-1 reverse transcriptase by RNA aptamers in Escherichia coli -- NICKENS et al. 9 (9): 1029 -- RNA Inhibition of HIV-1 reverse transcriptase by RNA aptamers in Escherichia coli Inhibition of HIV-1 reverse transcriptase by RNA aptamers in Escherichia coli -- NICKENS et al. Hizi, A., McGill, C., and Hughes, S.H. Expression of soluble, enzymatically active, human immunodeficiency virus reverse transcriptase in Escherichia coli and analysis of mutants. http://www.rnajournal.org/cgi/content/full/9/9/1029   (2532 words)      Nucleoside Reverse Transcriptase Inhibitors (NRTIs) for HIV & AIDS Experimental drugs are italicized, and approved drugs are in regular, non-italicized type. Nucleoside Reverse Transcriptase Inhibitors (NRTIs) for HIV and AIDS HIV's reverse transcriptase enzyme is needed to perform this process. http://www.aidsmeds.com/NRTIs.htm   (369 words)      Cutting Edge: Telomerase Activation in Human T Lymphocytes Does Not Require Increase in Telomerase Reverse ... Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts. Regulation of telomerase by alternate splicing of human telomerase reverse transcriptase (hTERT) in normal and neoplastic ovary, endometrium and myometrium. Constitutive and regulated expression of telomerase reverse transcriptase (hTERT) in human lymphocytes. http://www.jimmunol.org/cgi/content/full/166/8/4826   (4193 words)      Real-Time Quantification of Human Telomerase Reverse Transcriptase mRNA in Tumors and Healthy Tissues -- de Kok et al. ... Constitutive and regulated expression of telomerase reverse transcriptase (hTERT) in human lymphocytes. Human Telomerase Reverse Transcriptase mRNA Expression Assessed by Real-Time Reverse Transcription Polymerase Chain Reaction Predicts Chemosensitivity in Patients With Ovarian Carcinoma High telomerase reverse transcriptase (hTERT) messenger RNA level correlates with tumor recurrence in patients with favorable histology Wilms’ tumor. http://www.clinchem.org/cgi/content/full/46/3/313   (3555 words)      Low-Molecular-Weight Plasmid of Salmonella enterica Serovar Enteritidis Codes for Retron Reverse Transcriptase and ... Veterinary Research Institute, Hudcova 70, 621 32 Brno, Reverse transcriptase in a clinical strain of Escherichia coli: production of branched RNA-linked msDNA. by retron reverse transcriptases have been identified as multicopy http://jb.asm.org/cgi/content/full/183/9/2852   (3884 words)      HIV RT 3D Structures Index The HIV Drug Resistance Database at LANL and the HIV Drug Resistance Database at Stanford are both sources of information on sites in the protease and reverse transcriptase proteins which mutate to create drug resistance in the virus. Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance. The Reverse Transcriptase Structures Table at the Protein Structures Database (PDB) contains RT structures and RT-related stuctures (such as E. coli Klenow fragment), collected as a part of the September 2002 "Molecule of the Month" project at PDB. http://hiv-web.lanl.gov/content/hiv-db/STRUCTURE/RT.HTML   (979 words)      Notice to Readers: Updated Guidelines for the Use of Rifabutin or Rifampin for the Treatment and Prevention of ... A previously published report provided guidelines for managing the pharmacologic interactions that can result when patients receive protease inhibitors and nonnucleoside reverse transcriptase inhibitors (NNRTIs) for treatment of human immunodeficiency virus (HIV) infection together with rifamycins for the treatment of tuberculosis (TB) (1). Concurrent use of NRTIs and rifamycins is not contraindicated and does not require dose adjustments. The other class of antiretroviral agents available in the United States---nucleoside reverse transcriptase inhibitors (NRTIs) (zidovudine, didanosine, zalcitabine, stavudine, lamivudine, and the new drug abacavir [2])---are not metabolized by CYP450. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm4909a4.htm   (1090 words)      An Accurate Look into HIV The primary source of scientific results on reverse transcriptase (RT), the CABM is conducting X-ray crystallography studies on the enzyme. For extensive knowledge about HIV and its molecular biology, Larsen is relying upon Edward Arnold and his group at the Center for Advanced Biotechnology and Medicine (CABM) at Rutgers University. Teachers might show a less technical version in biology and biochemistry classes, while scientists might introduce their talks with the video and a more technical script. http://www.sdsc.edu/GatherScatter/GSsummer96/larsen.html   (1061 words)      Downstream E-Box-mediated Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene Transcription: Evidence ... Gu, J., Kagawa, S., Takakura, M., Kyo, S., Inoue, M., Roth, J.A., and Fang, B.L. Tumor-specific transgene expression from the human telomerase reverse transcriptase promoter enables targeting of the therapeutic effects of the Bax gene to cancers. Devereux, T.R., Horikawa, I., Anna, C.H., Annab, L.A., Afshari, C.A., and Barrett, J.C. DNA methylation analysis of the promoter region of the human telomerase reverse transcriptase (hTERT) gene. Majumdar, A.S., Hughes, D.E., Lichtsteiner, S.P., Wang, Z., Lebkowski, J.S., and Vasserot, A.P. The telomerase reverse transcriptase promoter drives efficacious tumor suicide gene therapy while preventing hepatotoxicity encountered with constitutive promoters. http://www.molbiolcell.org/cgi/content/full/13/8/2585   (7708 words)      Mutations in HIV reverse transcriptase which alter RNase H activity and decrease strand transfer efficiency are ... Structural studies of authentic HIV reverse transcriptase (RT) suggest a role for the p51 carboxyl terminus in forming an Mutations in HIV reverse transcriptase which alter RNase H activity and decrease strand transfer efficiency are suppressed by HIV nucleocapsid protein Mutations in HIV reverse transcriptase which alter RNase H activity and decrease strand transfer efficiency are suppressed by HIV nucleocapsid protein -- Cameron et al. http://www.pnas.org/cgi/content/full/94/13/6700   (4737 words)      Reverse Transcriptase-Polymerase Chain Reaction Validation of 25 "Orphan" Genes from Escherichia coli K-12 MG1655 -- ... Figure 1 Reverse transcriptase-polymerase chain reaction (RT-PCR) experiments. Figure 2 Control experiments required to validate each of the results in Table 1. The experiments have been replicated many times, allowing the tested open reading frames (ORFs) to be approximately ordered according to band intensities. http://www.genome.org/cgi/content/full/10/7/959   (4285 words)      Frequency of Mutations Conferring Resistance to Nucleoside Reverse Transcriptase Inhibitors in Human Immunodeficiency ... Frequency of Mutations Conferring Resistance to Nucleoside Reverse Transcriptase Inhibitors in Human Immunodeficiency Virus Type 1-Infected Patients in Korea -- Cho et al. Frequency of Mutations Conferring Resistance to Nucleoside Reverse Transcriptase Inhibitors in Human Immunodeficiency Virus Type 1-Infected Patients in Korea http://dx.doi.org/10.1128/JCM.40.4.1319-1325.2002   (346 words)      DNA Replication Enzymes Reverse Transcriptase from HIV-1 is of tremendous medical interest as it is the target enzyme for the best known of anti-AIDS drugs, AZT, which acts by causing chain termination of the polymerase reaction. Knowledge of its detailed three dimensional structure will greatly assist the development of knew anti-AIDS drugs. The polymerase function of RT is then able to synthesise the second strand of DNA, possibly primed by a rump of the viral RNA. http://www.biochem.ucl.ac.uk/bsm/xtal/teach/repl/rt.html   (357 words)      Substitution of proline 306 in the reverse transcriptase domain of hepatitis B virus regulates replication -- Lin et ... reverse transcriptase (rtP306) has been suggested to constrain Substitution of proline 306 in the reverse transcriptase domain of hepatitis B virus regulates replication -- Lin et al. Substitution of proline 306 in the reverse transcriptase domain of hepatitis B virus regulates replication http://vir.sgmjournals.org/cgi/content/abstract/86/1/85   (283 words)      Nucleoside Reverse Transcriptase Inhibitors The matrix below highlights key and common point mutations associated with the development of antiretroviral drug resistance and cross-resistance to Nucleoside Reverse Transcriptase Inhibitors (NRTI). Click on drug names, colored cells and mutations for additional and specific data. http://www.hivresistanceweb.com/protected/mutationtables/nrti.shtml   (53 words)      Interlaboratory Evaluation of a New Reverse Transcriptase Polymerase Chain Reaction-Based Enzyme-Linked Immunosorbent ... Interlaboratory Evaluation of a New Reverse Transcriptase Polymerase Chain Reaction-Based Enzyme-Linked Immunosorbent Assay for the Detection of Circulating Melanoma Cells: A Multicenter Study of the Dermatologic Cooperative Oncology Group -- Reinhold et al. http://www.jco.org/cgi/reprint/19/6/1723   (41 words)      Kivexa® - new one-a-day combination tablet for treatment of HIV launched Treatment with Kivexa will, in one single daily pill, provide the double NRTI backbone component of triple therapy. Kivexa (abacavir/lamivudine), the first once-a-day, fixed-dose combination of two nucleoside reverse transcriptase inhibitors (NRTIs) with potent and durable virological control and a low risk of cross resistance, launches in the UK. http://www.medicalnewstoday.com/medicalnews.php?newsid=18732&nfid=mnf   (789 words)      HIV drugs database, aids drugs database, antiviral drugs database, protease inhibitors database, anti-hiv medications, ... Official Website - Truvada.com; prescribing information, side effects, drug interactions Note: Same exact active ingrediend as Videx in a delayed release formulation for increase patient compliance. Rescriptor (delavirdine) - non nucleoside analog reverse transcriptase inhibitor http://www.coreynahman.com/antiHIVdrugdatabase61499.html   (1391 words)      Manufacturer of Pdgf dUTPase/dUTP Pfu Zinc Metallothionein Interleukin,Looking for distributor MMLV/MMuLV reverse transcriptase MMLV-RT Human Granulocyte Colony Stimulating Factor http://www.hnexport.com   (19 words)      hTERT Extends Proliferative Lifespan and Prevents Oxidative Stress-Induced Apoptosis in Human Lens Epithelial Cells -- ... Human Telomerase Reverse Transcriptase Immortalizes Bovine Lens Epithelial Cells and Suppresses Differentiation through Regulation of the ERK Signaling Pathway http://www.iovs.org/cgi/content/abstract/46/7/2503   (394 words)      Arch Dermatol -- Abstract: A Meta-analysis of Reverse Transcriptase-Polymerase Chain Reaction for Tyrosinase mRNA as a ... Uma Nadiminti, BA Arthur J. Sober, MD Michael Bigby, MD Arch Dermatol. Detection of Melanoma Cells in the Lymphatic Drainage after Lymph Node Dissection in Melanoma Patients by Using Two-Marker Reverse Transcriptase-Polymerase Chain Reaction Assay Arch Dermatol -- Abstract: A Meta-analysis of Reverse Transcriptase-Polymerase Chain Reaction for Tyrosinase mRNA as a Marker for Circulating Tumor Cells in Cutaneous Melanoma, March 2001, Tsao et al. http://archderm.ama-assn.org/cgi/content/abstract/137/3/325   (373 words)      Evaluation of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Primer tRNA Binding by Fluorescence ... The presence of both overlapping and separate p/t and tRNA binding regions on RT was tested by examination of the affinity of a possible RT bisubstrate type inhibitor, containing motifs proposed to be essential for both tRNA and p/t binding. molecule is utilized by human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) to prime DNA synthesis from the viral RNA genome. Evaluation of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Primer tRNA Binding by Fluorescence Spectroscopy: Specificity and Comparison to Primer/Template Binding http://pubs.acs.org/cgi-bin/abstract.cgi/bichaw/1996/35/i14/abs/bi9526387.html   (405 words)      Ever shorter telomere 1 (EST1)-dependent reverse transcription by Candida telomerase in vitro: Evidence in support of ... To characterize the effect of primer length on the observed CaEst1p dependence, we tested a series of primers with different that TERT mediates nucleotide addition through a reverse transcriptase-like Ever shorter telomere 1 (EST1)-dependent reverse transcription by Candida telomerase in vitro: Evidence in support of an activating function -- Singh and Lue 100 (10): 5718 -- Proceedings of the National Academy of Sciences http://www.pnas.org/cgi/content/full/100/10/5718   (3910 words)      HIV Resistance Testing: an Update -- Aslanzadeh 32 (4): 406 -- Annals of Clinical and Laboratory Science Keywords: HIV resistance testing, HIV mutations, antiviral agents, reverse transcriptase inhibitors http://www.annclinlabsci.org/cgi/content/abstract/32/4/406   (169 words)      Direct in situ reverse transcriptase-polymerase chain reaction -- Kher and Bacallao 281 (2): C726 -- AJP - Cell ... Detection of HIV-1 DNA and messenger RNA in individual cells by PCR-driven in situ hybridization and flow cytometry. Variation in cellular EGF receptor mRNA expression demonstrated by in situ reverse transcriptase polymerase chain reaction. Direct in situ reverse transcriptase-polymerase chain reaction -- Kher and Bacallao 281 (2): C726 -- AJP - Cell Physiology http://ajpcell.physiology.org/cgi/content/full/281/2/C726   (3432 words)      GLOSSARY R (the reverse of transcription); used by retroviruses as well as in biotechnology. http://www.emc.maricopa.edu/faculty/farabee/BIOBK/BioBookglossR.html   (1159 words)      Immortalized Fibroblast-Like Cells Derived from Human Embryonic Stem Cells Support Undifferentiated Cell Growth -- Xu ... extended by ectopic expression of human telomerase reverse transcriptase Key Words: Human embryonic stem cells · Human telomerase reverse transcriptase Telomerase ·; Immortalization · Differentiation http://stemcells.alphamedpress.org/cgi/content/abstract/22/6/972   (298 words)      Susceptibility of lamivudine-resistant hepatitis B virus to other reverse transcriptase inhibitors -- Ono-Nita et al. ... Susceptibility of lamivudine-resistant hepatitis B virus to other reverse transcriptase inhibitors -- Ono-Nita et al. Susceptibility of lamivudine-resistant hepatitis B virus to other reverse transcriptase inhibitors HBV M552I, M552V, and L528M/M552V mutants to other reverse transcriptase http://www.jci.org/cgi/content/abstract/103/12/1635   (818 words)      A Group II Intron-Type Open Reading Frame from the Thermophile Bacillus (Geobacillus) stearothermophilus Encodes a ... by reverse transcription is a widely used and essential technology Mailing address: Dept. of Health Sciences, Box 70673, East Tennessee State University, Johnson City, TN 37614. reverse transcribe RNA at temperatures as high as 75°C. * Corresponding author. http://aem.asm.org/cgi/content/abstract/70/12/7140   (303 words)      The L74V Mutation in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Counteracts Enhanced Excision of ... The L74V Mutation in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Counteracts Enhanced Excision of Zidovudine Monophosphate Associated with Thymidine Analog Resistance Mutations -- Miranda et al. The L74V Mutation in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Counteracts Enhanced Excision of Zidovudine Monophosphate Associated with Thymidine Analog Resistance Mutations virus type 1 (HIV-1) reverse transcriptase (RT) confer resistance http://aac.asm.org/cgi/content/abstract/49/7/2648   (390 words)

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