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Topic: Renal cell carcinoma


  
 Kidney cancer FAQs - National Foundation for Cancer Research
But, like radiation therapy, chemotherapy is not very effective in treating renal cell carcinoma.
The type of radiation therapy used in treating kidney cancer is external beam radiation therapy, which means the radiation is administered from a machine, and the procedure is a lot like having an x-ray.
For advanced cancer, radiation therapy may also be used to relieve symptoms of pain or bleeding.
http://www2.nfcr.org/site/PageServer?pagename=cancers_kidney_faqs   (2388 words)

  
 Biologictherapy.Org: Renal Cell Carcinoma: FAQs
For patients with metastatic RCC, systemic therapy with interferon, interkeukin-2, or experimental therapy is employed.
In patients who either present with — or develop — solitary metastatic lesions, aggressive surgical resection may be of value.
The interleukins are a family of polypeptides originally named for their ability to mediate interactions between leukocytes.
http://www.biologictherapy.org/renalcell/renal_faqs.html   (1360 words)

  
 eMedicine - Renal Cell Carcinoma : Article by Kush Sachdeva, MD
Parkinson DR, Sznol M: High-dose interleukin-2 in the therapy of metastatic renal-cell carcinoma.
Autologous vaccine therapy is now being tried in combination with cytokine therapy.
Medicine is a constantly changing science and not all therapies are clearly established.
http://www.emedicine.com/MED/topic2002.htm   (6029 words)

  
 Renal Cell Carcinoma
A fine needle aspiration was done to check for recurrence and metastasis of renal cell carcinoma.
Because most patients still do not respond to interleukin-2 and there is no clear evidence of improved survival, immunotherapy alone should not be considered effective therapy for renal-cell carcinoma.
Black, 1997, says that combination therapy increases the toxic effects without improving response.
http://learn.sdstate.edu/craigg/Fuhrer.html   (2608 words)

  
 eMedicine - Renal Cell Carcinoma : Article by Deborah Baumgarten, MD, MPH
Image-guided radiofrequency or cryogenic ablation has been used to treat patients with RCC, especially patients with a high surgical risk, aversion to surgery, or bilateral lesions.
Intervention: Because RCCs are usually resistant to chemotherapy and radiation therapy, surgical resection offers the best likelihood of cure.
These techniques should not be used as the primary modalities in the workup of suspected RCC.
http://www.emedicine.com/radio/topic601.htm   (3840 words)

  
 THE MERCK MANUAL, Sec. 17, Ch. 233, Genitourinary Cancer
Aortography and selective renal artery angiography may be used to define the nature of renal cell carcinoma and provide a more accurate description of the number of renal arteries present and the vascular pattern before surgery, particularly before nephron-sparing surgery.
A chest x-ray is essential because pulmonary metastases occur frequently.
Metastatic renal cell carcinoma has a poor prognosis because it is radioresistant, and traditional chemotherapeutic drugs, alone or in combination, and progestational drugs are ineffective.
http://www.merck.com/pubs/mmanual/section17/chapter233/233b.htm   (298 words)

  
 Disease Category Listing (363): Renal Cell Carcinoma
New Haven; Medical Oncology and Hematology, P.C. A Phase 3, Three-Arm, Randomized, Open-Label Study of Interferon Alfa Alone, CCI-779 Alone, and the Combination of Interferon Alfa and CCI-779 in First-Line Poor-Prognosis Subjects With Advanced Renal Cell Carcinoma.
A Phase 3, Three-Arm, Randomized, Open-Label Study of Interferon Alfa Alone, CCI-779 Alone, and the Combination of Interferon Alfa and CCI-779 in First-Line Poor-Prognosis Subjects With Advanced Renal Cell Carcinoma.
http://www.centerwatch.com/patient/studies/cat363.html   (2893 words)

  
 Hypoxia upregulates von Hippel-Lindau tumor-suppressor protein through RhoA-dependent activity in renal cell carcinoma ...
Expression of pVHL was quantified by densitometric analysis and expressed as means ± SE for 3 separate experiments relative to normoxic values.
of vimentin networks was little affected by hypoxia in carcinoma
Our results are supported by another study in which pVHL increased
http://ajprenal.physiology.org/cgi/content/full/286/2/F338   (6140 words)

  
 Understanding familial and non-familial renal cell cancer -- Bodmer et al. 11 (20): 2489 -- Human Molecular Genetics
therefore a role in RCC development was suggested (39).
are associated with such a risk of RCC development.
clear family history of papillary RCC, and it was therefore
http://hmg.oupjournals.org/cgi/content/full/11/20/2489   (7467 words)

  
 MIR Teaching file case rs014
The value of renal scintigraphy in the workup of renal mass lesions comes from its ability to provide functional information prior to surgical intervention.
References and General Discussion of Renal Scintigraphy (Anatomic field:Skeletal System, Category:Neoplasm, Neoplastic-like condition)
The patient has known metastatic disease to bone.
http://gamma.wustl.edu/rs014te143.html   (469 words)

  
 Kidney Cancer - Renal Cell Carcinoma (RCC)
Other researchers are studying how different genetic changes seen in RCC affect how the cancer looks under the microscope and how likely it is to grow and spread aggressively.
RCC is difficult to treat and rarely cured once it has spread beyond the kidney and current therapies have limited efficacy.
Doctors hope to use this information to treat RCC more effectively in new ways that cause fewer side effects.
http://www.cornellurology.com/uro/cornell/kidney/gi/rcc.shtml   (1227 words)

  
 Proleukin - Aldesleukin for Injection
View "Voices of Experience" — the story of Karen Velasquez, a patient, and the healthcare team who managed her stage IV melanoma with Interleukin-2 therapy.
A guide for patients with metastatic renal cell carcinoma
IL-2 (aldesleukin) received FDA approval for treatment in metastatic renal cell carcinoma (kidney cancer) in 1992, and for treatment in metastatic melanoma (a type of skin cancer) in 1998.
http://www.proleukin.com   (143 words)

  
 Renal cell carcinoma -- Facts, Info, and Encyclopedia article
Radiation therapy may be used to palliate the symptoms of skeletal metastases.
IL-2 (Proleukin®) is presently the only therapy FDA-approved for the treatment of metastatic renal cell carcinoma (kidney cancer).
((medicine) the treatment of disease (especially cancer) by exposure to radiation from a radioactive substance) Radiation therapy is not commonly used for treatment of renal cell carcinoma because it is usually not successful.
http://www.absoluteastronomy.com/encyclopedia/r/re/renal_cell_carcinoma.htm   (1239 words)

  
 MIR Teaching file case pt056
Miyauchi et al., Correlation between visualization of primary renal cancer by FDG-PET and histopathological findings.
One study (Bachor et al., 1996) evaluating 29 patients with solid renal masses demonstrated a sensitivity of 77% (20 of 26 patients with renal cancer)and 3 false positives (angiomyolipoma, pericytoma and pheochromocytoma).
Although a positive FDG-PET is useful in evaluating renal cell cancer, a negative scan does not exclude this type of cancer.
http://gamma.wustl.edu/pt056te183.html   (461 words)

  
 Encyclopedia Search - Medical Dictionary Search Engines
Aging changes in the bones - muscles - joints
Acute respiratory distress syndrome see ARDS (acute respiratory distress syndrome)
Adult respiratory distress syndrome see ARDS (acute respiratory distress syndrome)
http://medical-dictionary-search-engines.com/encyclopedia/?encyclopedia_name...   (474 words)

  
 Helping Patients Make Informed Treatment Choices
Most Popular Guides: Atrial Fibrillation Bipolar Disorder Chronic Lymphocytic Leukemia Peripheral Neuropathy Ductal Carcinoma in Situ
Where can you locate doctors, researchers, hospitals and medical centers with specialized interest and expertise in the disease?
http://www.medifocus.com   (209 words)

  
 Biologictherapy.Org: Renal Cell Carcinoma: Epidemiology
RCC is curable only in patients presenting with resectable, early-stage disease.
The most common presentation of renal cell cancer is a solitary renal mass that may cause symptoms of pain and hematuria.
Cigarette smoking has been identified as a risk factor and the incidence of RCC is significantly increased in endstage renal patients who develop acquired cystic kidney disease.
http://www.biologictherapy.org/renalcell/renal_rcc_epid.html   (164 words)

  
 National Cancer Institute - Renal Cell Cancer Treatment
Because a majority of patients are diagnosed when the tumor is still relatively localized and amenable to surgical removal, approximately 40% of all patients with renal cancer survive 5 years.
National Cancer Institute - Renal Cell Cancer Treatment
Renal cell cancer is one of the few tumors in which well-documented cases of spontaneous tumor regression in the absence of therapy exist, but this occurs very rarely and may not lead to long-term survival.
http://www.cancer.gov/cancerinfo/pdq/treatment/renalcell/healthprofessional   (285 words)

  
 Renal Cell Carcinoma, Ellis Fischel Cancer Center, University of Missouri Health Care
Though not curable by current treatment methods, metastatic renal cell carcinoma can be effectively treated to improve symptoms and survival in a proportion of patients using immunotherapy, radiation therapy, or surgery in certain cases.
Immunotherapy drugs used against renal cell carcinoma include interleukin-2, interferon-alpha, and interferon-gamma.
Slowly growing tumors may not cause symptoms and may not need to be treated right away, but rapidly growing tumors will make the patient ill within weeks.
http://www.ellisfischel.org/urologic/kidney.shtml   (339 words)

  
 Renal Cell Carcinoma - Genetics
The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched-related gene, TRC8.
Renal Cell Carcinoma : Clinical and Epidemiological Information
Renal cell cancer: chromosome 3 translocations as risk factors.
http://www.cancerindex.org/geneweb/X210201.htm   (200 words)

  
 Kidney cancer, OnTumor.com
Renal Cell Cancer - From the Medical Reference Library of HealthAnswers.com Has good but brief information about the disease, its cause, symptoms, diagnosis, prevention, prognosis, treatment, and much more.
How is Renal Cell Carcinoma Treated - Treatment information from the National Cancer Institute.
- provides information on immune based therapies for treating stage IV kidney cancer (metastatic renal cell carcinoma).
http://www.cancerlinksusa.com/kidney.htm   (460 words)

  
 Renal cell carcinoma
Russco P. Renal cell carcinoma: presentation, staging and surgical treatment.
All renal neoplasms should be regarded as potentially malignant
Diagnosis can often be confirmed by renal ultrasound
http://www.surgical-tutor.org.uk/specialities/urology/gravitz.htm   (214 words)

  
 Sloan-Kettering - Prediction Tools: Renal Cell Carcinoma
This nomogram can be used to predict the five-year probability of treatment failure among patients with newly-diagnosed renal cell carcinoma.
Researchers at Memorial Sloan-Kettering have developed a nomogram that combines prognostic factors to predict the likelihood of recurrence after surgery for renal cell carcinoma.
Visit PubMed to view abstracts of the journal articles that support this nomogram.
http://www.mskcc.org/mskcc/html/6156.cfm   (111 words)

  
 Renal cell carcinoma
The cancerous cells are made up of clear or granular cytoplasm with centrally located nuclei (right).
enal cell or clear cell carcinoma is the most common type of carcinoma affecting the kidney.
High magnification: note the striking contrast between the two sides below (left and right).
http://www.brown.edu/Courses/Digital_Path/Kidney/renal_cell_carcinoma.htm   (107 words)

  
 MedlinePlus: Kidney Cancer
Renal Cell Cancer (PDQ): Treatment (National Cancer Institute)
How Is Kidney Cancer (Renal Cell Carcinoma) Treated?
What Are the Risk Factors for Kidney Cancer (Renal Cell Carcinoma)?
http://www.nlm.nih.gov/medlineplus/kidneycancer.html   (265 words)

  
 Renal Cell Carcinoma - page 4
Chromophobe renal cell carcinoma is a distinct subtype of renal cell carcinoma and comprises approximately 5% of neoplasms of the renal tubular epithelium (1).
Chromophobe renal cell carcinoma should be distinguished from renal oncocytoma (2).
Chromophobe carcinomas, like oncocytomas, are well circumscribed and can have a mahogany-like colour if they contain a predominant number of eosinophilic granular cells.
http://sup.ultrakohl.com/Cases99/sep99/cotm9-4.html   (198 words)

  
 Renal Pathology
This microscopic appearance is why they are often called "clear cell carcinomas".
This is the classic histologic appearance of a renal cell carcinoma: the neoplastic cells have clear cytoplasm and are arranged in nests with intervening blood vessels.
http://www-medlib.med.utah.edu/WebPath/RENAHTML/RENAL055.html   (38 words)

  
 Renal Cell Carcinoma
Here are some examples of the most common kidney cancer, renal cell carcinoma.
The cells have a clear cytoplasm and you can see their borders easily.
The third picture shows the typical histopathology of a renal cell carcinoma.
http://www.pathguy.com/~dlaporte/rcc.htm   (125 words)

  
 The role of von Hippel-Lindau tumor suppressor protein and hypoxia in renal clear cell carcinoma -- Sufan et al. 287 ...
VHL patients or in the majority of sporadic clear cell renal
The role of von Hippel-Lindau tumor suppressor protein and hypoxia in renal clear cell carcinoma -- Sufan et al.
287 (1): F1 -- AJP - Renal Physiology
http://ajprenal.physiology.org/cgi/content/abstract/287/1/F1   (236 words)

  
 Carcinoma, Renal Cell
Renal Cell Carcinoma is a rare malignant kidney disorder.
Major symptoms may include loss of kidney function, fever, weight loss, blood problems, high levels of calcium in the system, high blood pressure, blood clots and congestive heart failure.
Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
http://my.webmd.com/hw/kidney_cancer/nord815.asp   (418 words)

  
 UroToday - Urology news and information resource for physicians
BERKELEY, CA (UroToday.com) - Nonmyeloablative allogeneic stem cell transplantation as a therapy for metastatic renal cell carcinoma remains a controversial treatment strategy for a disease where there seems to be multiple new treatment approaches but no clear best therapeutic approach.
Nonmyeloablative Allogeneic Stem Cell Transplantation For Metastatic Renal Cell Carcinoma: Refining Patient Selection
BERKELEY, CA (UroToday.com) - Reactive stromal tissue initiates during prostatic intraepithelial neoplasia and exhibits characteristics of myofibroblast wound repair, and is tumor promoting.
http://www.UroToday.com   (363 words)

  
 Renal Cell Carcinoma
Light microscopy (A) and Ultrastructure (B) of the Clear Cell Variant
Figure 5A: Relatively large epithelial cells with clear cytoplasmic arranged in nests separated by fibrous septa.
Pediatric Renal Cell Carcinoma 2% of All Cases
http://sup.ultrakohl.com/uscap/abs-1998/renalca.htm   (59 words)

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