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| | Remifentanil |
 | | Among the opioids, remifentanil behaves like it has an "on and off switch" and the practitioner needs to be aware of five ways in which the patient can manifest undesirable effects and for which anesthesiologists and anesthetists must be prepared. | | | It is most important that the anesthesiologist using remifentanil plan in advance for the management of postoperative pain for patients who are expected to experience it. | | | (2) The bradycardia and hypotension produced by remifentanil are muted or prevented by pretreatment with an anticholinergic such as 0.4 mg glycopyrolate intravenously, and both can be treated by a sympathomimetic drug such as ephedrine. |
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http://www.apsf.org/resource_center/newsletter/1996/fall/Remi.html
(1278 words)
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| | REMIFENTANIL: Clinical use of an evanescent opioid. |
| | Remifentanil is in the same structural family as fentanyl and the other phenylpiperidines. | | | Remifentanil is 15 times more potent than alfentanil, based on the ED50 to achieve loss of response to a verbal command and 20 times more potent than alfentanil based on the EC50. | | | In another open, prospective trial, 28 patients were randomly allocated to receive continuous infusions of remifentanil (6 mg/kg/min) or propofol (180 mg/kg/min) for sedation during spinal or axillary regional anesthesia. |
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http://faculty.washington.edu/bramhall/lectures/opioids/remife~1.htm
(4428 words)
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| | A New Approach For Induction Anaesthesia With Propofol Target Controlled And Remifentanil |
| | Remifentanil and alfentanil are the faster onset of the opioids in clinical practice, but the incidence of bradicardia, hypotension and rigid chest are the main problems with them. | | | Educational considerations for the clinical introduction and use of remifentanil. | | | Bolus dosis of remifentanil can cause hypotension, rigid chest and bradicardia, because is difficult do it slow(90 or 120 seconds) without pump infusion. |
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http://www.eurosiva.org/Archive/Lisbon/Posters/Nora.htm
(628 words)
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| | Gallileus - Biomedcentral Open Access Articles |
| | The proportions of patients experiencing pain during the maintenance phase were similar in the two groups, with 51% of patients in the remifentanil group having at least moderate pain as compared with 49% of patients in the fentanyl group. | | | Rapid offset of analgesia with remifentanil resulted in a greater incidence of pain, highlighting the need for proactive pain management when transitioning to longer acting analgesics, which is difficult within a double-blind study but would be quite possible under normal circumstances. | | | A further 26 patients (who all received open-label remifentanil; referred to hereafter as 'practice patients') were treated at the remaining sites (up to 2 patients per site) to allow familiarization with the protocol procedures. |
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http://www.gallileus.info/search/bmc_detail?id=cc2398
(6591 words)
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| | REMIFENTANIL FOR PAIN REDUCTION DURING RETROBULBAR INJECTION |
| | Remifentanil seems to be particularly useful to reduce or avoid the sensation of pain during the application of retrobulbar anesthesia. | | | With the new opioid Remifentanil a drug seems to be available for the first time that appears very promising with regard to pain seduction during injection. | | | Exclusion criteria were presurgical pain, low compliance, analgetic medication and initial oxygen saturation below 93º/a |
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http://www.dog.org/engl/abstract97/P481.html
(297 words)
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| | Ultiva Injection , SPC from the eMC |
| | Muscle rigidity induced by remifentanil must be treated in the context of the patient's clinical condition with appropriate supporting measures including ventilatory support. | | | Paediatric patients should be monitored and the dose titrated to the depth of analgesia appropriate for the surgical procedure. | | | There is no evidence that remifentanil is extracted during renal replacement therapy. |
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http://emc.medicines.org.uk/emc/assets/c/html/DisplayDoc.asp?DocumentID=14766
(5899 words)
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| | GASNet Anesthesiology: Comparison of Remifentanil and Fentanyl in Patients Undergoing Craniotomy for Supratentorial ... |
| | Remifentanil reportedly reduces electroencephalogram activity, cerebral blood flow, and intracranial pressure in isoflurane-anesthetized dogs. | | | However, remifentanil hydrochloride will need more extensive clinical investigation before it replaces established practice and techniques. | | | Patients in the two groups had similar median times to emergence, but many more patients given remifentanil had normal recovery scores within 1 hr. |
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http://gasnet.med.yale.edu/sa/1998/04/05_br.php
(774 words)
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| | Remifentanil Injection - Drugs & Vitamins - Drug Library - DrugDigest |
| | Remifentanil is used mostly during surgery or while you are recovering from surgery. | | | REMIFENTANIL (Ultiva®) helps to induce and maintain anesthesia and sedation during and after surgery or other procedures. | | | It is given by a specially trained health care professional in a hospital or clinic setting. |
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http://www.drugdigest.org/DD/PrintablePages/Monograph/0,7765,8223,00.html
(394 words)
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| | Remifentanil Prevents the Hemodynamic Response to Orotracheal Intubation |
| | Therefore, caution should be used when using this technique in patients who could be compromised by marked hypotension such as those with a fixed cardiac output sate. | | | Remifentanil Prevents the Hemodynamic Response to Orotracheal Intubation | | | We wanted to allow our patients to be fully awake before induction of anesthesia. |
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http://www.jrnlappliedresearch.com/articles/Vol1Iss2/Alexander.htm
(2176 words)
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| | An Appraisal of the Elan Pharma / Packer Forbes Remifentanil Simulation Courses |
| | Ivor Pain; Post-open cholecystectom Patient sedated with remifentanil and propofol :To ensure that the patient had received appropriate pain relief to prevent potential re-intubation due to pain.Mrs. | | | Comments from individual questionnaires suggest that the most useful aspects of the course were the scenarios and the explanations of the drug use in an ITU environment. | | | CXR shows right-sided Pneumothorax requiring an intercostal drain: To increase remifentanil infusion during painful procedures and reduce post-procedure. |
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http://www.bris.ac.uk/Depts/BMSC/SMS05.htm
(465 words)
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| | Remifentanil - an update |
| | A designer drug developed in the laboratories of Glaxo (as it was then) in the Research Triangle of North Carolina – it was to change how opioids were used in anaesthesia. | | | the relationship between infusion rate and opioid concentration will be less variable for remifentanil than for other available opioids. | | | If we take an ampoule of remifentanil off the shelf from the drug cupboard and proceed to give it to a patient we can examine, along the way, some of the newer evidence that exists – both in the literature and from usage data from a district general hospital that began using remifentanil in 1997. |
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http://www.sivauk.org/Belfast/Kapila.htm
(363 words)
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| | Ovid: Glass: Anesth Analg, Volume 94(4).April 2002.771-774 |
| | Surprisingly, the results of these and other studies have not been consistent and this has led to some controversy (11). | | | These studies contrast with the study by Olufolabi et al. | | | In these patients, remifentanil was associated with a frequent incidence of adverse effects including respiratory depression (as evidenced by peripheral oxygen desaturation), nausea and vomiting, sedation, and facial pruritus. |
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http://anes.anesthes.sunysb.edu/MiscItems/Saunders_Glass02.html
(1832 words)
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| | Remifentanil TCI |
| | no information on the use of remifentanil TCI in children or in ICU patients. | | | published studies, remifentanil was given by TCI to 1,895 patients and 42 volunteers | | | The clinical efficacy and safety of remifentanil TCI has been demonstrated and |
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http://www.sivauk.org/Glasgow/Abstracts/Glen.htm
(896 words)
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