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| | Receptor Localization: Laboratory Methods and Procedures (Receptor Biochemistry and Methodology) by Marjorie A. Ariano ... |
 | | Receptor Localization: Laboratory Methods and Procedures is the first user-friendly guide to the latest techniques and approaches being employed to examine the localization of neurotransmitter receptors in the central nervous system and peripheral tissues. | | | Receptor Localization: Laboratory Methods and Procedures is an invaluable guide for researchers in the related fields of neurology, biochemistry, and pharmacology. | | | Its lucid descriptions of new detection methods, inclusion of experimental examples, and emphasis on how these experimental approaches are applicable to particular research areas will appeal to both the experienced researcher and novice investigator. |
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http://www.gettextbooks.com/isbn_0471165719.html
(354 words)
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| | University of Pennsylvania: School of Veterinary Medicine |
| | Thus, my primary research focus has been on using mutational approaches, i.e. | | | Thus, I frequently interact with my colleagues here at the University of Pennsylvania who study the actions of peptides that control feeding and satiety, such as melanocortins and neuropeptide Y. Selected Publications | | | The ability to manipulate these processes via the AT2 receptor may hold some clinical benefit in controlling wound healing and the treatment of heart disease. |
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http://w3.vet.upenn.edu/faculty/dkyee
(1248 words)
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| | [No title] |
| | Johns Hopkins Univ. School of Medicine, Baltimore, MD - Ph.D. Biochemistry | | | Weigel, J.A. and Weigel, P.H. (2003) Characterization of the recombinant rat 175-kDa hyaluronan receptor for endocytosis (HARE). | | | Purification and subunit characterization of the rat liver endocytic hyaluronan receptor. |
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http://w3.ouhsc.edu/biochem/ocmg/Weigel.htm
(3164 words)
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| | Wiley::Regulation of G Protein Coupled Receptor Function and Expression: Receptor Biochemistry and Methodology |
| | Receptor Localization: Laboratory Methods and Procedures edited by Marjorie A. Ariano | | | Covering a broad range of fundamental concepts and methodologies which are current in the study of GPCRs, Regulation of G Protein-Coupled Receptor Function and Expression is a vital reference for receptor biochemists, pharmacologists, neuroscientists, molecular biologists, cell biologists, and physiologists. | | | Understanding how GPCRs are regulated is critical in determining waysto control their function and expression. |
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http://eu.wiley.com/WileyCDA/WileyTitle/productCd-0471252778.html
(339 words)
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| | Talk:Receptor (biochemistry) - Wikipedia, the free encyclopedia |
| | Conclusion: 1) Properly, the latter kind should not be discussed in this article. | | | However, this article conflates both these kind of receptors, which recognize neurotransmitters, hormones, etc., and immune receptors, which are on a region of antibody molecules and recognize antigens. | | | This article should be moved and edited to correct this. |
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http://en.wikipedia.org/wiki/Talk:Receptor_(biochemistry)
(174 words)
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| | Receptor Biochemistry: a Practical Approach; Paperback |
| | One of three volumes covering practical aspects of neurotransmitter and hormone-receptor-ligand interactions, receptor biochemistry and receptor-effector coupling. | | | Prices subject to change to be advised on confirmation of order. |
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http://www.opengroup.com/dfbooks/019/0199630933.shtml
(136 words)
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| | Estrogen Receptor Accessory Proteins: Effects on Receptor-DNA Interactions |
| | Environmental Health Perspectives (EHP) is a monthly journal of peer-reviewed research and news on the impact of the environment on human health. | | | A recent study using baculovirus-overexpressed human GR in Spodoptera frugiperda cells suggested that hsp70 is associated with the GR-GRE complex (31). | | | ER activity was less affected in this model. |
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http://ehp.niehs.nih.gov/members/1995/Suppl-7/landel-full.html
(4871 words)
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| | [No title] |
| | RESEARCH INTEREST: Research in my laboratory focuses on the biochemistry of trans-membrane signal transduction, with particular emphasis on the dopaminergic systems. | | | 26.Senogles, S.E. and Quasney, M.W. (1996) Use of transfection techniques to study the function of D2 dopamine receptors. | | | My laboratory is currently using a variety of techniques, including antisense RNA and analysis of chimeric D2/D3 receptors to elucidate the functional consequences of D3 dopamine receptor activation. |
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http://drnelson.utmem.edu/faculty/senogles.html
(843 words)
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| | MBG: George Hess |
| | Kinetic investigations in the microsecond time region using a laser-pulse photolysis technique. | | | Malfunction of the receptors is implicated in many diseases of the nervous system, and the receptor proteins are the targets of a large class of clinically important compounds and abused drugs. | | | This goal has already been achieved with the nicotinic acetylcholine receptor from the electric organ (modified muscle) of certain fish. |
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http://www.mbg.cornell.edu/MBG_Faculty_Detail.cfm?id=16
(1362 words)
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| | The EMBO Journal |
| | EMBO member Paolo Lusso reviews the progress made in the field of HIV and chemokines and describes new insights gained into HIV's entry mechanism and pathogenesis, as well as prospects for developing new therapeutic measures. | | | Guthridge et al show that mutually exclusive phosphorylation of Ser585 and Tyr577 within the GM-CSF receptor acts as a binary switch mediating the pleiotropic biological response to graded cytokine concentrations. | | | The EMBO Journal, EMBO reports provides sharply focused short papers and review articles in all areas of molecular biology. |
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http://embojournal.npgjournals.com/cgi/content/full/16/2/281
(320 words)
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| | Dale F. Mierke |
| | Physical and structural characterization of biopolymers in solution using experimental (NMR spectroscopy, EPR spectroscopy, fluorescence, circular dichroism) and theoretical techniques. | | | Pellegrini, M., Bremer, A. E., Ulfers, A. L., Boyd, N. D., Mierke, D. (2001) Molecular characterization of the substance P/neurokinin-1 receptor complex: development of an experimentally based model. | | | Rölz, C., Mierke, D. (2001) Characterization of the molecular motions of constitutively active G protein-coupled receptors for parathyroid hormone. |
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http://biomed.brown.edu/Faculty/M/Mierke.htm
(325 words)
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| | Cliff Robinson's Resume |
| | Identified novel disulfide-bonding interactions and other determinants of 2AR folding and stability. | | | Robinson, C.R., and Sligar, S.G. (1994) "Hydrostatic Pressure Reverses Osmotic Pressure Effects on the Specificity of EcoRI-DNA Interactions." Biochemistry 33, 3787-3793. | | | The goals of this project were to design, produce, and characterize functional analogs of the 2 adrenergic receptor and other GPCRs. |
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http://www.udel.edu/chem/robinson/crr_cv.html
(1086 words)
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| | [No title] |
| | The research of the laboratory is aimed at the function of receptors in terms of molecular structures. | | | The main approaches are to identify the residues that line the binding sites and conduction pathways, to determine the three-dimensional structures, to locate the critical residues in these three-dimensional structures, and to detect changes in the structures corresponding to changes in functional states. | | | We try to understand how receptors recognize specific ligands, how the binding of these ligands is converted into the opening of ion-conducting channels (or into an interaction with GTP-binding proteins), how the selectivity of the channels is determined, and how ions are conducted through the channels. |
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http://cpmcnet.columbia.edu/dept/gsas/biochem/faculty/karlin.html
(347 words)
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| | Expert in: Biochemisty, Cell Biology |
| | He has extensive experience characterizing the specificity and affinity of receptor interactions and subsequent internalization of receptor-ligand complexes. | | | Additionally, he is knowledgeable of site-directed mutagenesis approaches to studying the structure-function of receptors reconstituted in transfected cells. | | | These areas are essentially identical and represent expertise that Expert has developed and strengthened in his laboratory research after his doctoral work. |
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http://www.intota.com/viewbio.asp?bioID=603815&perID=108471
(874 words)
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| | Platelet receptor biochemistry and regulation |
| | This results in the recruitment of specific signalling molecules that bind to the receptor and thereby stimulate the activation of a number of cell signalling pathways. | | | Binding of collagen to GPVI results in the stimulation of intracellular signalling that results in platelet aggregation. | | | Platelets also possess receptors for thrombin, which is generated at sites of injury, and therefore thrombin can also stimulate platelet activation. |
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http://www.ams.rdg.ac.uk/DMCB/platelets/plreceptbioch.html
(484 words)
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| | Joseph J. Falke |
| | The approach involves the development of novel techniques to analyze the structures of these switch proteins, as well as the structural changes and docking events triggered by their activation. | | | Because of their critical role in the initiation of cellular signals and their accessibility to extracellular hormones and drugs, chemoreceptors are rapidly becoming a prominent research target in the fields of signaling biology and medicine. | | | The same methods proven successful in the aspartate receptor are being applied to representative GPCR systems that will serve as models for the large superfamily. |
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http://www.colorado.edu/chemistry/grad/faculty/Falke/Falke.htmlOLD
(1412 words)
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| | Kunio Misono - Department of Biochemistry and Molecular Biology, University of Nevada |
| | We apply techniques of structural biology (X-ray crystallography), biochemistry, biophysics, and molecular biology to pursue our research goals. | | | Our research aims to determine the structure of ANP receptor at atomic resolution and to elucidate its signal transduction mechanism. | | | Structural studies of the natriuretic peptide receptor: a novel hormone-induced rotation mechanism for transmembrane signal transduction (review). |
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http://www.ag.unr.edu/biochemistry/Directory/Misono.htm
(447 words)
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| | Jheem D. Medh |
| | We are studying various components of the atherogenesis pathway including apolipoproteins, lipases and lipoprotein receptors. | | | In a related study, we are employing in vitro studies in cultured cells to examine the cellular mechanisms of cholesterol efflux from cultured macrophages. | | | Recent studies have established that LPL and HTGL also function as apoproteins and ligands for lipoprotein receptors, associate with lipoprotein particles and hepatic lipoprotein receptors, and thereby enhance lipoprotein catabolism and clearance. |
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http://www.csun.edu/~hfchm006/chemjm.html
(811 words)
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| | MU Biochemistry - Dennis B. Lubahn |
| | Our working hypothesis is that estrogen responses in behavior, in bone, in glucose homeostasis, and in the reproductive, immune, and cardiovascular systems may not be mediated exclusively by the classical ER α | | | The main long-term goals of my research program are to find novel functions for estrogens and the receptors, and then to identify the molecular mechanisms mediating these functions. | | | Using these mouse model system we are characterizing the 4-hydroxyestradiol and methoxychlor responses and the putative 4-hydroxyestradiol and methoxychlor receptors. |
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http://www.biochem.missouri.edu/dlubahn.php
(711 words)
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| | Powell's Books - Genetic Manipulation of Receptor Expression and Function (Receptor Biochemistry and Methodology) by ... |
| | Genetic Manipulation of Receptor Expression and Function provides a comprehensive review of the principles and applications for genetic manipulation of receptor expression and function. | | | Receptor biochemists, neuroscientists, molecular biologists, cell biologists, and molecular geneticists will find Genetic Manipulation of Receptor Expression and Function a useful guide. | | | By providing the necessary conceptual framework of transgenic and knockout technologies, Genetic Manipulation of Receptor Expression and Function offers a concise and easily accessible analysis for researchers. |
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http://www.powells.com/biblio?isbn=0471350575
(240 words)
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| | University Of Kentucky - Deneys Van der Westhuyzen |
| | Oxidized and modified lipoproteins play a key role in the development of atherosclerosis and our laboratory is studying various scavenger receptors that mediate the metabolism of such lipoprotein particles. | | | We have shown that SR-BI exists as alternatively-spliced variants and we are currently studying the significance and biological functions of these receptor isoforms. | | | Research in my laboratory is focused on lipoprotein receptors and how such receptors contribute to or protect against atherosclerosis. |
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http://www.mc.uky.edu/Biochemistry/dept_personnel/faculty/westhuyzen.asp
(1100 words)
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| | Dr. James V. Staros |
| | The primary biological systems under study are the ErbB receptor family and their ligands, the archetypes of which are epidermal growth factor (EGF) and its receptor. | | | We are currently expanding our kinetic studies to investigate the effects of coexpression of other ErbB family receptors with the EGF receptor and to investigate how differences in kinetics of ligand capture and release correlate with changes in downstream signaling. | | | We are working to elucidate the mechanisms by which the binding of polypeptide hormones to their cell surface receptors are transduced into signals in the cell and mechanisms by which those signals are regulated. |
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http://www.sunysb.edu/biochem/BIOCHEM/facultypages/staros
(913 words)
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| | Publications |
| | Implications for familial hypercholesterolemia from structure of the LDL receptor YWTD-EGF domain pair. | | | Global defects in the expression and function of the LDL receptor associated with two familial hypercholesterolaemia mutations resulting in misfolding of the LDLR EGF-AB pair. | | | Structure of LDL receptor module reveals molecular mechanisms of familial hypercholesterolemia. |
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http://pathology.bwh.harvard.edu/blacklow/publications.html
(700 words)
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| | MU Biochemistry - Gary A. Weisman |
| | Our laboratory possesses the relevant molecular reagents and cell systems needed to progress these projects and participating graduate students gain experience in a variety of techniques in molecular and cell biology. | | | We have undertaken efforts to determine the molecular mechanisms whereby activation of P2 receptors can be employed for the treatment of human disease. | | | These expression systems have enabled us to identify and purify the P2 receptor protein and current research is directed towards investigating structural features of the receptor that affect its functions. |
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http://www.biochem.missouri.edu/gweisman.php
(416 words)
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| | Mark E. Dumont - Faculty Page |
| | Components of this yeast signal transduction pathway are homologous to, and in some cases functionally interchangeable with, corresponding components of mammalian signaling systems. | | | Genomic approaches to membrane protein structure and function: Although membrane proteins constitute 20-30% of the coding potential of genomes, methods for analyzing their structures and functions are still primitive compared to the approaches available for studies of soluble proteins. | | | G protein signaling: G protein coupled receptors mediate cellular responses to a variety of sensory stimuli, hormones, growth factors, and neurotransmitters and are targets of a number of widely prescribed drugs. |
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http://dbb.urmc.rochester.edu/bcbp/members/faculty/Dumont_Mark.HTMl
(720 words)
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| | Laboratory of Molecular Biology and Biochemistry |
| | Sakmar, T.P. Structure of rhodopsin and the superfamily of seven-helical receptors: the same and not the same. | | | Sakmar, T.P. Structure and Function of G Protein-Coupled Receptors: Lessons from the Crystal Structure of Rhodopsin. | | | Sakmar, T. Molecular Mechanism of Signal Transduction by Rhodopsin. |
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http://www.rockefeller.edu/labheads/sakmar/publications.php
(2739 words)
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| | Regulation of G Protein Coupled Receptor Function and Expression: Receptor Biochemistry and Methodology |
| | This volume covers methods used to examine how the function(s) of receptors are regulated. | | | * Covers a broad range of important concepts and methodologies which are current in the study of G protein-coupled receptors (GPCRs) | | | Recent advances in molecular and cell biology enabling the cloning, expression, and mutagenesis of signal transduction proteins has prompted an explosion of knowledge in the field of receptor regulation, facilitating the discovery of new classes of regulatory proteins, and providing a basis and means for manipulating receptor function through multiple intracellular targets. |
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http://store.totalbookstore.com/0471252778.html
(216 words)
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| | Gordon Tollin, Biochemistry and Molecular Biophysics, University of Arizona |
| | We have developed a new spectroscopic tool, called plasmon-waveguide resonance, that allows one to monitor conformational changes in real time in a single lipid bilayer occurring as a consequence of the functional activity of membrane proteins, without the use of labels of any kind. | | | We are applying this to a variety of membrane systems, including GPCRs such as the delta opioid receptor, the beta-2-adrenergic receptor, the cannabinoid receptor and rhodopsin, and ion channels such as the nicotinic acetylcholine receptor. | | | Redox proteins may be soluble or membrane-associated, and electron transfer can occur via both inter- and intra-protein reactions. |
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http://www.biochem.arizona.edu/dept/ppl/Profiles/tollin.html
(698 words)
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| | Publications page |
| | D.R. Madden (2002) The structure and function of glutamate receptor ion channels. | | | Glutamate receptor ion channels: structural insights into molecular mechanisms. | | | Piserchio, A. Fellows, D.R. Madden, and D.F. Mierke (2005) Association of the cystic fibrosis transmembrane conductance regulator with CAL: structural features and molecular dynamics. |
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http://www.dartmouth.edu/~madden/papers.html
(341 words)
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| | MCB Faculty studying Receptor Biochemistry |
| | GPCR signaling transduction, membrane signaling complexes of beta adrenergic receptors and their function in cardiac myocyte | | | Regulation of gene repression; Biochemistry of chromatin modifying machines; Xenopus as a model to study FSH Muscular Dystrophy | | | Regulation of gene expression, signal transduction, and cell proliferation by hormones and growth factors; mechanisms of hormone and antihormone action in normal and cancer cells; functional analyses of nuclear hormone receptors |
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http://www.life.uiuc.edu/mcb/research/topics/receptor_bioch.html
(239 words)
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| | Goldstein, Jellinger and Riederer (1983) Basic aspects of receptor biochemistry: Proceedings of the international ... |
| | Goldstein, Jellinger and Riederer (1983) Basic aspects of receptor biochemistry: Proceedings of the international symposium, Vienna, September 10-12, 1982 | | | To view the the latter's ratings, click on Chapters/Papers/Articles in the STATISTICS box, select a publication from the list that appears, and then click on either Quality or Interest in that publication's STATISTICS box. | | | Basic aspects of receptor biochemistry: Proceedings of the international symposium, Vienna, September 10-12, 1982 |
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http://www.getcited.org/?PUB=102284280&showStat=Ratings
(98 words)
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| | Molecular and Chemical Characterization of Membrane Receptors (Receptor Biochemistry and Methodology, Vol 3) - Price ... |
| | The Genetics Revolution: Programs & Issues for the Community College Automated DNA Sequencing and Analysis From Genome to Therapy: Integrating New Technologies with Drug Development - No. 229 Membranes, Detergents, and Receptor Solubilization (Receptor Biochemistry and Methodology, Vol 1) Benzodiazepine/Gaba Receptors and Chloride Channels: Structural and Functional Properties (Receptor Biochemistry and Methodology, Vol 5) | | | Become the first one to review this product! | | | Molecular and Chemical Characterization of Membrane Receptors (Receptor Biochemistry and Methodology, Vol 3) |
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http://books.compricer.com/0471834343
(209 words)
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| | [No title] |
| | Please wait while we find you the best price for Identification and Expression of G-protein Coupled Receptors (Receptor Biochemistry andamp; Methodology), this should take no more than 30 seconds. | | | Identification and Expression of G-protein Coupled Receptors (Receptor Biochemistry and Methodology) | | | Identification and Expression of G-protein Coupled Receptors (Receptor Biochemistry andamp; Methodology) Kevin R. Lynch ISBN: 047119493x |
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http://www.bookhead.co.uk/047119493X.aspx
(82 words)
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| | Find in a Library: Receptor biochemistry and methodology. |
| | To find this item in a library, enter a postal code, state, province, or country in the field above. | | | Find in a Library: Receptor biochemistry and methodology. | | | WorldCat is provided by OCLC Online Computer Library Center, Inc. on behalf of its member libraries. |
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http://worldcatlibraries.org/wcpa/ow/d96932a61d5e9c7da19afeb4da09e526.html
(43 words)
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| | Transmembrane Transporters (Receptor Biochemistry and Methodology) |
| | Resources: unsecured bad credit loans Apply Now - Boating Stories from Rainbow Seeker - Microsoft MapPoint 2005/6 - Buy Links from LinkBliss | | | Books : Transmembrane Transporters (Receptor Biochemistry and Methodology) |
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http://www.mappointmag.com/amazon/default-item_id-0471065137-search_type-AsinSearch-locale-us.html
(30 words)
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