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Topic: Ramipril



  
 Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus:
Ramipril reduced the risk of a combined microvascular outcome of overt nephropathy, dialysis, or laser therapy by 16% (1­29, p=0·036).
Of surviving participants at 1 year, 1486 (84%) patients in the ramipril group and 1516 (88%) in the placebo group were still taking study drugs, as were 1045 (65%) and 992 (66%), respectively, at the end of the study.
Ramipril also lowered the risk of overt nephropathy, renal failure, or laser therapy.
http://www.diabetes-mellitus.org/hope.htm   (4618 words)

  
 In Chronic Nephropathies Prolonged ACE Inhibition Can Induce Remission: Dynamics of Time-Dependent Changes in GFR -- ...
Ramipril (1.25 to 5 mg/d) and conventional therapy
In patients on continued ramipril, the breakpoint analysis found that GFR time-dependent changes could not be described by one single first degree equation, but rather by two different equations (Left Panel) from randomization to 36 mo and from 36 to 54 mo, respectively.
cohort of patients on continued ramipril therapy, but not in
http://jasn.asnjournals.org/cgi/content/full/10/5/997   (4913 words)

  
 Prescribing Information : Altace ® (Ramipril)
Because the hypotensive effect of ramipril is achieved through vasodilation and effective hypovolemia, it is reasonable to treat ramipril overdose by infusion of normal saline solution.
Laboratory determinations of serum levels of ramipril and its metabolites are not widely available, and such determinations have, in any event, no established role in the management of ramipril overdose.
Of the total number of patients who received ramipril in US clinical studies of ALTACE 11.0% were 65 and over while 0.2% were 75 and over.
http://www.vidyya.com/archives/1007_4.htm   (5881 words)

  
 Altace (Ramipril) Reverses Heart Enlargement/Cuts Cardiovascular Risk
Results announced in 1999, showed ramipril reduced the risk of cardiovascular deaths by 25 percent, heart attack by 20 percent, and stroke by 32 percent, Dr. Mathew reports.
In this HOPE sub-study, researchers examined the electrocardiograms (ECG) of 8,281 patients at the beginning and end of the four-and-a-half-year study, comparing the prevalence, regression or development of LVH, together with patient outcomes such as heart attacks, stroke and heart failure.
The rate of strokes, heart attacks and cardiovascular deaths among those who did not develop LVH or experienced regression was 12.3 percent, while the rate was 15.8 percent among individuals who developed LVH or experienced no regression.
http://www.pslgroup.com/dg/207A22.htm   (791 words)

  
 Ramipril - Drugs & Vitamins - Drug Library - DrugDigest
Ramipril controls high blood pressure (hypertension) by relaxing blood vessels; it is not a cure.
Ask your prescriber or health care professional what your blood pressure should be and when you should contact him or her.
Do not treat yourself for coughs, colds, or pain while you are using ramipril without asking your prescriber or health care professional for advice.
http://www.drugdigest.org/DD/PrintablePages/Monograph/0,7765,585,00.html   (665 words)

  
 Ramipril - Patient UK
Ramipril works by causing blood vessels to relax, lowering blood pressure and increasing the supply of blood and oxygen to the heart.
Before taking any 'over-the-counter' medicines, check with your pharmacist which medicines are safe for you to take with Ramipril.
Never give it to others, even if their condition appears to be the same as yours.
http://www.patient.co.uk/showdoc/30002360   (836 words)

  
 DaytonDailyNews Health : Integrative Medicine  :  Drugs   :  Ramipril
If you have an allergy to ramipril or any other part of the medicine.
This lowered blood pressure also protects the weakened heart and helps improve fluid removal from the body.
DaytonDailyNews Health : Integrative Medicine  :  Drugs   :  Ramipril
http://www.daytondailynews.com/health/altmed/shared/health/alt_medicine/ConsDrugs/Ramiprilcd.html   (688 words)

  
 Prolonged use of ramipril prevents stroke
Widespread use of a drug such as ramipril in patients at high risk of stroke is likely to have a major impact on public health, they conclude.
Although reduction in blood pressure was modest, the risk of any stroke was reduced by 32% in the ramipril group compared with the placebo group.
The risk of fatal stroke was reduced by 61% and significantly fewer patients on ramipril had mental or functional impairment.
http://www.eurekalert.org/pub_releases/2002-03/bmj-puo032002.php   (240 words)

  
 Health Library -
Your pharmacist has additional information about ramipril written for health professionals that you may read.
Continue to take ramipril and talk to your doctor if you experience
Before taking ramipril, tell your doctor if you are taking any of the following drugs:
http://yalenewhavenhealth.org/library/healthguide/en-us/drugguide/topic.asp?hwid=d00728a1   (1320 words)

  
 Effect Of Ramipril On Non-Diabetic Proteinuric Nephropathy
Once this therapy fails or if it is not possible, then the patient is managed symptomatically with non-specific anti-proteinuric drugs, with an aim of decreasing proteinuria.
Time to ESRD, survival, and direct costs of conservative and renal replacement therapy were analyzed.
Ramipril prolongs life and is cost effective in chronic proteinuric nephropathies.
http://www.indegene.com/Nep/Jour/indJour_KI_Sum_01-01-2001_4.asp   (366 words)

  
 Hypertension Online Slides - ace, REIN, Ramipril Efficacy in Nephropathy Study
The Ramipril Efficacy In Nephropathy (REIN) study is the second clinical trial to confirm that ACE inhibitors have a similar action in patients with chronic non-diabetic nephropathies.
In this prospective double-blind trial, 352 patients were classified according to baseline proteinuria (stratum 1: 1-3 grams/24-hrs; stratum 2: =3 grams/24-hrs), and randomly assigned ramipril or placebo plus conventional antihypertensive therapy targeted at achieving diastolic blood pressure
Data analysis for 56 ramipril-assigned patients and 61 placebo-assigned patients showed the decline in GFR per month was significantly lower in the ramipril group than the placebo group (0.53 vs 0.88 ml/min, P=0.03).
http://www.hypertensiononline.org/slides2/slide01.cfm?q=ace&dpg=22   (286 words)

  
 Online NewsHour: Hope for the Heart -- November 11, 1999
What we don't know is whether the other ACE inhibitors have similar effects because they have not been studied as well as this drug was studied in this particular trial.
New England Journal of Medicine early relase on Ramipril
So right now, Ramipril is the drug that appears to be the one that would be the agent in focus for treating patients such as these.
http://www.pbs.org/newshour/bb/health/july-dec99/heart_11-11.html   (1154 words)

  
 British Journal of Pharmacology - Abstract of article: Ramipril-induced delayed myocardial protection against free ...
The aim of the present study was to examine whether ramipril induces delayed myocardial protection against free radical injuries ex vivo and to determine the possible role of the bradykinin B
In conclusion, ramipril induces delayed myocardial protection against free radical injury in the rat heart.
Rats were pretreated with ramipril (10 or 50
http://www.nature.com/bjp/journal/v125/n3/abs/0702089a.html   (341 words)

  
 Ramipril - Diabetes Mellitus, Type 2, Type 1, and Metabolic Disorders treatment and medications
Ramipril also cut the need for heart bypass surgery and coronary angiography, decreasing the proportion of patients who required revascularization procedures by 16%.
Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on death from cardiovascular causes, myocardial infarction, and stroke in high-risk patients.
None of the patients had heart failure, a common reason for treatment with ramipril, one of the ACE inhibitor family of drugs.
http://www.medicinenet.com/script/main/art.asp?articlekey=11075   (719 words)

  
 ACC Clinical Trials
There were highly significant reductions in each of the separate endpoints in the ramipril group: cardiovascular death (25%), MI (20%), and stroke (32%).
Ramipril arm: patients were randomized to ramipril (up to 10 mg.
The ramipril arm was terminated early because of clear reductions in the primary endpoint among patients treated with this agent.
http://www.acc.org/education/online/trials/esc99/hope.htm   (443 words)

  
 Diabetes REduction Assessment with ramipril and rosiglitazone Medication
Diabetes REduction Assessment with ramipril and rosiglitazone Medication
http://www.dream-ctn.org   (17 words)

  
 Ramipril in Feline Cardiomyopathy - WSAVA 2002
Secondly, the clinical findings from the initial examinations are compared with the results of control examinations and thus the effectiveness of ramipril is documented.
Ramipril treatment was combined with thyrostatic treatment (carbimazole) in cats suffering from hyperthyroidism, and both drugs proved to be effective and did not produce side effects.
Ramipril treatment not only appeared to be safe in combination with the loop diuretic furosemide but also with the thyrostatic drug carbimazole and with ß-methyldigoxin in the cats in the present study.
http://www.vin.com/proceedings/Proceedings.plx?CID=WSAVA2002&PID=2800   (619 words)

  
 Ramipril
Fever and chills, sore throat and hoarseness, sudden difficulty breathing or swallowing, swelling of the face, mouth, or extremities, impaired kidney function (ankle swelling, decreased urination), confusion, yellow discoloration of the eyes or skin (indicating liver disorder), intense itching, chest pain or palpitations, abdominal pain.
Children may be especially sensitive to the effects of ramipril.
Ramipril should be used with caution by patients with severe kidney disease or renal artery stenosis (narrowing of one or both of the arteries that supply blood to the kidneys).
http://www.wholehealthmd.com/refshelf/drugs_view/1,1524,542,00.html   (610 words)

  
 Ramipril - Wikipedia, the free encyclopedia
ACE inhibitors lower the production of Angiotensin II, therefore relaxing arterial muscles while at the same time enlarging the arteries, allowing the heart to pump blood easier, and increasing blood flow due to more blood being pumped into and through bigger passageways.
Ramipril (marketed as Tritace® or Altace®) is an angiotensin converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure.
The half-life of ramiprilat is variable (3 - 16 hours), and is prolonged by heart and liver failure, as well as kidney failure.
http://en.wikipedia.org/wiki/Ramipril   (130 words)

  
 Altace (Ramipril) Purchase from Canada for Less Money
Symptoms of low blood pressure are likely to be the primary warning of an Altace overdose.
Altace (Ramipril) Purchase from Canada for Less Money
http://www.canadianprescriptionsavers.com/druginfo/A/altace.html   (1263 words)

  
 American Family Physician: FDA Approval of Ramipril for Cardiovascular Disease - Altace
Rates of reduction of cardiovascular events included 32 percent for stroke, 20 percent for myocardial infarction, 26 percent for cardiovascular death and 22 percent for all three endpoints combined.
Patients who are hypersensitive to ramipril or who have a history of angioedema related to previous treatment with an angiotensin-converting enzyme (ACE) inhibitor should not use ramipril.
FDA Approval of Ramipril for Cardiovascular Disease - Altace
http://www.findarticles.com/p/articles/mi_m3225/is_7_63/ai_72469789   (292 words)

  
 Altace (Ramipril Capsules) : Buy Altace (Ramipril Capsules) at ABC Online Pharmacy
Altace/Ramipril helps by smoothening the flow of blood in the vessels, thereby helping heart to function normally.
Altace, a Drug consisting of Ramipril compound, Altace/Ramipril an ACE-inhibitor and used for the treatment of problems related to heart, like high blood pressure and heart failure.
Altace/Ramipril consists of a compound called Ramipril, which works by reducing the pressure of blood thereby helping in the prevention of the formation of angiotensin II, which is a hormone in the body that causes blood vessels to contract.
http://www.abconlinepharmacy.com/ns/customer/product1019-c-p1   (984 words)

  
 WorstPills.org - Search Results for ramipril (ALTACE)
Search results below include drug profiles where your selected drug is a primary subject of discussion
Search results below include Disease and Drug Family Information where your selected drug is a primary subject of discussion
benazepril (LOTENSIN); benazepril and hydrochlorothiazide (LOTENSIN HCT); captopril (CAPOTEN); captopril and hydrochlorothiazide (CAPOZIDE); enalapril (VASOTEC); enalapril and hydrochlorothiazide (VASERETIC); fosinopril (MONOPRIL); lisinopril (PRINIVIL, ZESTRIL); lisinopril and hydrochlorothiazide (PRINZIDE, ZESTORETIC); moexipril (UNIVASC); perindopril (ACEON); quinapril (ACCUPRIL); ramipril (ALTACE); trandolapril (MAVIK)
http://www.worstpills.org/results.cfm?drug_id=556   (522 words)

  
 The Angiotensin-Converting Enzyme Inhibitor Ramipril Is Found to Prevent Cardiovascular Events in Diabetes Patients ...
The researchers concluded that ACE inhibition with ramipril represents a new macrovascular and microvascular preventive therapy for diabetes patients, and that the preventive effects of ramipril for macrovascular disease are independent of changes in blood pressure.
Ramipril was found to significantly reduce the risk of nephropathy (as defined by an albumin-creatinine ratio >36 mg/mmol) by 22% (P=0.045), and overt nephropathy, laser therapy for diabetic retinal disease, or renal dialysis by 15% (P=0.05).
To address the possibility that the effect of ramipril was due to its well-known blood pressure–lowering effect, the researchers controlled for change in blood pressure during the study and found that ramipril still reduced the risk of the primary outcome by 25%.
http://www.ndei.org/v2/website/litalerts/article.cfm?article_id=115   (506 words)

  
 Ramipril for the Prevention and Treatment of Cardiovascular Disease -- Vuong and Annis 37 (3): 412 -- The Annals of ...
Ramipril for the Prevention and Treatment of Cardiovascular Disease -- Vuong and Annis 37 (3): 412 -- The Annals of Pharmacotherapy
Articles by Vuong, A. Articles by Annis, L. Ramipril for the Prevention and Treatment of Cardiovascular Disease
Whether this effect is specific to ramipril has yet to
http://www.theannals.com/cgi/content/abstract/37/3/412   (316 words)

  
 Good Long-Term Results For Patients On Ramipril After Heart Attack
The original study investigated treatment of patients after acute myocardial infarction (AMI) heart attack with the drug ramipril.
The authors go on to recommend that "once a clinician has decided to treat an individual patient with an ACE inhibitor after AMI, therapy should be continued indefinitely, unless tolerance develops".
The findings were positive with a significant reduction in relative risk of dying found in patients who had been allocated ramipril.
http://www.pslgroup.com/dg/2983E.htm   (453 words)

  
 Ramipril, Eastern Carolina
Ramipril is an angiotensin-converting enzyme (ACE) inhibitor, a family of drugs used to treat high blood pressure and some types of heart failure.
For additional evidence-based information on diseases, conditions, symptoms, diagnosis, treatment and wellness issues, continue searching the Healthwise Knowledgebase.
Therefore, people should consult their healthcare practitioner before supplementing additional potassium and should have their blood levels of potassium checked periodically while taking ACE inhibitors.
http://www.uhseast.com/116809.cfm   (642 words)

  
 News - Ramipril Reduces Advanced Glycation End Products In Non-Diabetic Nephropathy
A group of non-diabetic nephropathy patients taking diuretics and beta-blockers were also enrolled as were as age- and sex-matched healthy controls.
In general, the baseline characteristics of patients taking diuretics and beta-blockers did not differ from those in the ramipril group.
Researchers from the Institute of Preventive and Clinical Medicine and the Military Hospital, Bratislava, Slovakia, as well as the University Wuerzburg, Germany, enrolled 12 patients with newly diagnosed mild-to-moderate non-diabetic nephropathy, who received ramipril for two months.
http://www.docguide.com/news/content.nsf/news/8525697700573E1885256D0A002D53EA   (451 words)

  
 Business Wire: Ramipril Comprehensive: Biovail Reports Positiv... @ HighBeam Research
The Phase IV clinical study evaluating the safety and efficacy of G-99 versus ramipril in Stage I and II hypertensive patients has been recently completed.
The results of this study, in conjunction with an earlier hypertension study, confirm the therapeutic advantages of G-99.
In this study, both G-99 and ramipril were dosed in the evening.
http://www.highbeam.com/library/doc0.asp?DOCID=1G1:93514611&refid=holomed_1   (652 words)

  
 Ramipril use in Canada
The Canadian-led Heart Outcomes Prevention Evaluation (HOPE) involved patients in 19 countries and showed that treatment with ramipril reduced mortality rates, cardiovascular events, complications related to diabetes and the development of diabetes.
Tu and colleagues state their findings show a "clear and striking increase" in the number of elderly Ontario residents started on ACE-inhibitor therapy.
In a related commentary, Louise Pilote discusses whether this huge increase in ramipril prescriptions was warranted and the effect widespread media coverage of the study had on physicians' decision to prescribe the drug.
http://www.eurekalert.org/pub_releases/2003-03/cmaj-rui022803.php   (247 words)

  
 Ramipril Dosage, Interactions, Side Effects, How to Use
Home > Drug Prescribing Database > R > Ramipril Dosage, Interactions, Side Effects, How to Use
Ramipril Dosage, Interactions, Side Effects, How to Use
Ramiprilat has approximately six times the ACE inhibitory activity than ramipril.
http://www.healthdigest.org/drug-prescribing-database/ramipril-2076.htm   (315 words)

  
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 Altace / Ramipril Lawsuit Overview - Find Trial Lawyers and Attorneys with Experience in Altace / Ramipril Personal ...
The Food & Drug Administration approved Altace for use in hyper-tensive patients in 1991.
Altace / Ramipril Lawsuit Overview - Find Trial Lawyers and Attorneys with Experience in Altace / Ramipril Personal Injury Law
An estimated 300,000 workplace injuries occur each year in the United States.
http://www.injuryboard.com/view.cfm/Topic=703   (421 words)

  
 ramipril - OneLook Dictionary Search
ramipril : The On-line Medical Dictionary [home, info]
Ramipril : RxList The Internet Drug Index [home, info]
ramipril : Dorland's Illustrated Medical Dictionary [home, info]
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 Hypertension Online Slides - AASK, amlodipine, ramipril, metoprolol, beta-blocker
In an attempt to address these issues, the AASK trial enrolled 1,094 African American patients with renal disease at 21 US centers, and randomized them to receive an ACE inhibitor (ramipril), the dihydropyridine antagonist, amlodipine, or a beta-blocker (metoprolol).
AASK is the first major study of kidney disease in this population.
Interim results show a 1.6 fold relative risk with amlodipine vs ramipril for the combined event (decrease in GFR, dialysis, or death).
http://www.hypertensiononline.org/slides2/slide01.cfm?q=AASK   (202 words)

  
 Altace - Tritace (Ramipril) - Buy Online Without Prescription Needed
Altace l is used to treat high blood pressure and heart failure.
Buy cheap Altace - Ramipril online without prescriptions needed.
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 ALTACE ALTACE (ramipril) and Medications
Do not take ALTACE during pregnancy, as death or injury to your unborn child may result, or if you've experienced serious side effects related to previous ACE inhibitors.
The contents of this Web site are intended for access and use by residents of the United States.
(ramipril) is a registered trademark of King Pharmaceuticals, Inc.
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 The latest news on... RAMIPRIL
For the most up-to-date approval information, please locate this API using the drug index.
Click here for the latest news on this API.
Altace (ramipril) Capsules, King Pharma, Labeling Revision
http://www.betterchem.com/news/RAMIPRIL   (40 words)

  
 FDA Warning Letter, King Pharmaceuticals (Altace (ramipril) Capsules)
The announcement letter promotes Altace for unapproved uses, contains unsubstantiated superiority claims, and lacks fair balance.
• Altace (ramipril) has unique properties related to lipid solubility, half-life, tissue specificity, ACE affinity, and binding
FDA Warning Letter, King Pharmaceuticals (Altace (ramipril) Capsules)
http://www.pharmcast.com/WarningLetters/September2000/King0900WL.htm   (523 words)

  
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