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Topic: Radiocontrast



  
 Coronary catheterization - Wikipedia, the free encyclopedia
By design, the catheter is smaller than the lumen of the artery it is placed in; internal blood pressures are monitored through the catheter to verify that the catheter does not block blood flow.
The X-Ray source and imaging camera equipment are on opposite sides of the patient's chest and freely move, under motorized control, about the patient's chest position in space so that images can be quickly taken from multiple different angles.
As much hydraulic brute force is applied as judged needed and visualized to be effective to make the stenosis of the artery lumen visibly enlarge.
http://en.wikipedia.org/wiki/Coronary_catheterization

  
 [No title]
The relative risk of contrast nephropathy was not related to the amount of radiocontrast media given or to the degree of chronic renal insufficiency before the procedure.
We aimed to assess the efficacy of acetylcysteine to prevent contrast nephropathy after administration of radiocontrast media in patients with chronic renal insufficiency.
Methods: We did a meta-analysis of randomised controlled trials comparing acetylcysteine and hydration with hydration alone for preventing contrast nephropathy in patients with chronic renal insufficiency.
http://www.molgen.mpg.de/~markowet/bib/birck03nacetyl

  
 FlowMedica, Inc.
Radiocontrast nephropathy: importance and clinical outcomes after percutaneous coronary interventions.
The definition of the point at which a patient develops radiocontrast nephropathy varies from physician to physician
Nephrotoxicity of ionic and nonionic contrast media in 1196 patients: a randomized trial.
http://www.flowmedica.com/faq.htm

  
 Allergy & Asthma Disease Management Center: Ask the Expert: Radiocontrast Reactions
Despite comments sometimes made in the lay media and by some physicians, there is no evidence supporting the contention that shellfish allergy has anything to do with the iodine content of such foods.
There seems to be quite a bit of conflicting information concerning shellfish allergy and iodine allergy.
Does a shellfish allergy predict an allergy iodine (radiocontrast, SSKI, povidone-iodine)?
http://www.aaaai.org/aadmc/ate/radiocontrast.html

  
 Gazi Týp Fakültesi - Gazi Medical Journal
Contrast nephropathy can be defined as an acute impairment of renal function that follows exposure to radiocontrast materials and for which alternative explanations for renal impairment have been eliminated (2).
The renal hemodynamic changes of the rats were inferred from blood pressures and pulse rates measured in real time during the experiment.
Group 1 rats were infused with 8.9 ml / kg (or 2.9 gr of iodine / kg of body weight) Na diatrizoate (Urovision, 1500 mosm / kg).
http://www.med.gazi.edu.tr/gmj/96-2a.html

  
 Brazilian Journal of Medical and Biological Research - Ionic radiocontrast inhibits endothelium-dependent ...
Role of nitric oxide (EDRF) in radiocontrast acute renal failure in rats.
Following removal of the contrast, vascular relaxation in response to the agonists returned to normal.
The pathophysiologic role of NO in contrast medium nephrotoxicity is a matter of controversy.
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000200014

  
 CJEM JCMU 2004; 6(4):253-8 :: Pharmacotherapy
The exact incidence of RIN for patients requiring ED contrast studies is unknown.
Conclusion: Although further study may be indicated, current evidence does not suggest that NAC has a role in the emergency prevention of RIN.
Moreover, investigators who attempted to determine the highest-risk patients through multivariate analyses did so using post-hoc methodologies on small groups of patients.
http://www.caep.ca/004.cjem-jcmu/004-00.cjem/vol-6.2004/v64.253-8.htm

  
 Allergy & Asthma Disease Management Center: Ask the Expert: Drug Reaction
Although just one patient, it does seem to bear out my notion that sensitivity to iodine/inorganic iodides could indeed to related to at least the delayed reaction to iodinated radiocontrast.
To our knowledge, there is no report of dermatitis due to iopento or others non-ionic contrast media because of iodine allergy.
Presently, I am writing an article that addresses the issues of "iodine allergy" and its relationship to "allergic" reactions to iodinated radiocontrast.
http://www.aaaai.org/aadmc/ate/drugreaction.html

  
 FlowMedica, Inc.
1) the prevention of radiocontrast nephropathy (RCN), a condition resulting from the use of radiocontrast agents during coronary and peripheral interventional and diagnostic procedures, and
FlowMedica is currently focused on two major conditions that can compromise the performance of the kidneys and lead to life-threatening problems:
http://www.flowmedica.com/focus.htm

  
 Postgraduate Medicine: Common allergic and allergic-like reactions to medications
Dr Craig is associate professor of medicine, chief of allergy/immunology service, and director of asthma and allergy clinical research, division of pulmonary, allergy, and critical care, Penn State University College of Medicine, Hershey, Pennsylvania.
This article focuses on common reactions to aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) and those arising from use of penicillins and sulfonamides.
Increased risk of serious reactions to radiocontrast media has been reported in patients receiving beta-adrenergic antagonists, patients with a previous history of reaction, and those with underlying cardiovascular disease, especially congestive heart failure, or asthma.
http://www.postgradmed.com/issues/1999/03_99/craig.htm

  
 Capa da Med Online 10
Kurnik, B.R., Weisberg, L.S., Cuttler, I.M. and Kurnik, P.B. Effects of atrial natriuretic peptide versus mannitol on renal blood flow during radiocontrast infusion on chronic renal failure.
Deve ser iniciado horas antes da exposição ao contraste e deve ser mantido por algumas horas após a infusão do contraste.
Weisberg, L.S., Kurnik, P.B. and Kurnik, B.R. Risk of radiocontrast nephropathy in patients with or without diabetes mellitus.
http://www.medonline.com.br/med_ed/med10/contras.htm

  
 The endogenous insulin-like growth factor system in radiocontrast nephropathy -- Symon et al. 274 (3): 490 -- AJP - ...
This is the first study that examines the response of the entire IGF system in reaction to radiocontrast utilizing a model
Table 2 presents a summary of the directional changes in the expression of the IGF-I system observed in the present model
was unchanged in the kidney cortex and medulla of rats with radiocontrast
http://ajprenal.physiology.org/cgi/content/full/274/3/F490

  
 Postgraduate Medicine: Complications of Diabetes Symposium: Dealing with diabetic nephropathy
In the secondary-prevention group, who already had mild retinopathy, patients who received intensive therapy had a significant decrease in both microalbuminuria (43%) and macroalbuminuria (56%).
Aggressive antihypertensive therapy, especially with ACE inhibitors, can reduce renal decline by half.
Inadequate treatment of hypertension, use of radiocontrast materials or potentially nephrotoxic drugs, overuse of diuretics, and urinary tract infection may hasten progression to end-stage renal disease and should be carefully avoided (5).
http://www.postgradmed.com/issues/1999/02_99/bell.htm

  
 Brazil Issues Warning About Radiocontrast Celobar, Cites Deaths
The radiocontrast, a barium, is being analyzed by the National Institute for Quality Control in Health (INCQS), which expects to have results in two weeks.
Anvisa said it is somewhat satisfied that other barium products have not caused the problems.
Brazil’s National Agency of Sanitary Monitoring (Anvisa) issued a warning 2 June concerning the use of a radiocontrast, Celobar.
http://www.raps.org/s_raps/view.asp?CID=116&DID=21138

  
 allergy iodine shellfish
a shellfish allergy predict an allergy iodine (radiocontrast, SSKI, povidone- iodine)?
http://www.allergy-guide.net/allergy-iodine-shellfish

  
 Radiocontrast - Definition of Radiocontrast by Webster's Online Dictionary
Radiocontrast - Definition of Radiocontrast by Webster's Online Dictionary
http://www.webster-dictionary.org/definition/Radiocontrast

  
 Postgraduate Medicine: Renal Problems Symposium: Nephrolithiasis
Therapy --There is no specific therapy for established radiocontrast nephropathy.
Other medications also have nephrotoxic potential when they are prescribed in specific patient populations.
Risk of radiocontrast nephropathy in patients with and without diabetes mellitus.
http://www.postgradmed.com/issues/1996/12_96/thatte.htm

  
 American Family Physician: Drugs to be used with caution in patients with asthma - includes patient information sheet
Drug interactions may result in an acute exacerbation of asthma.
Aspirin, beta-adrenergic antagonists and radiocontrast agents may precipitate or worsen asthma symptoms.
Family physicians should be adept in the use of five classes of medication in patients with asthma.
http://www.findarticles.com/p/articles/mi_m3225/is_n3_v54/ai_18724106

  
 JAMA -- Prevention of Radiocontrast Nephropathy: Back to Basics, May 19, 2004, Chertow 291 (19): 2376
JAMA -- Prevention of Radiocontrast Nephropathy: Back to Basics, May 19, 2004, Chertow 291 (19): 2376
In this issue of THE JOURNAL, the study by Merten and colleagues
Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.
http://jama.ama-assn.org/cgi/content/extract/291/19/2376

  
 UpToDate Iodinated radiocontrast agents in the treatment of hyperthyroidism
Reference to these materials is no substitute for medical advice based on individual patient assessment, and may not be applicable in all circumstances.
Iodinated radiocontrast agents in the treatment of hyperthyroidism
UpToDate Iodinated radiocontrast agents in the treatment of hyperthyroidism
http://www.patients.uptodate.com/topic.asp?file=thyroid/5827&title=undefined

  
 UpToDate Radiocontrast media-induced acute renal failure
A review of the pathogenesis and clinical characteristics of radiocontrast media-induced nephropathy is presented here.
Many important issues remain unresolved including the pathogenesis and treatment of this problem and the relative nephrotoxicity of different iodinated radiocontrast agents.
The nephrotoxic properties of these agents appears to vary, with nonionic low- and iso-osmolal agents being associated with a relatively decreased incidence of renal injury among high-risk patients ( See "Nonionic agents" below).
http://www.patients.uptodate.com/topic.asp?file=renlfail/9576&title=undefined

  
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Radiocontrast medium-induced declines in renal function: a role for oxygen free radicals.
Adenosine modulates this vasoconstrictor response and is postulated to increase oxygen free radical (OFR) generation.
Department of Physiology, Mayo Graduate School of Medicine, Rochester, Minnesota 55905.
http://darwinpharmacy.com/ref-allopurinol/allopurinol-research-abs3.567.html

  
 [No title]
Both haemodynamic changes and nephrotoxic effects are observed.
However, patients requiring radiocontrast procedures often suffer from many of the risk factors above.
Role for endothelin in the renal responses to radiocontrast media in the rat.
http://www.portfolio.mvm.ed.ac.uk/studentwebs/session1/group35/pathophys/radio.html

  
 UIC College of Pharmacy Drug Information Center
Assuming that reactive oxygen species play a role in the pathophysiology of this condition, a recent study published in the New England Journal of Medicine looked at acetylcysteine as another agent to help reduce the risk of renal dysfunction.
However, certain patient populations are predisposed to an increased risk.
With the evolution of medical diagnostics within the last 50 years, the expanding use of radiocontrast agents has led to a surge of radiocontrast induced renal dysfunction as well as increased awareness about the possibility of this adverse effect.
http://www.uic.edu/pharmacy/services/di/nac.htm

  
 Role of N-acetylcysteine in the prevention of radiocontrast-induced nephropathy -- Brophy 36 (9): 1466 -- The Annals of ...
STUDY SELECTION: Pertinent English-language animal and human studies were reviewed.
DATA SOURCES: A literature search of MEDLINE (1966-December 2001) was performed using the following search terms: N-acetylcysteine, nephropathy, acute renal failure, and radiocontrast.
http://www.theannals.com/cgi/content/abstract/36/9/1466

  
 Dr. Hale's Breastfeeding and Medications Forum: Radiocontrast Agent Table
It should not be a problem for breastfeeding mothers or their infants.
Visipaque (iodixanol) is not that different for any of the 100 or more other radiocontrast agents.
There is no reason to assume this agent is any more toxic than all the other radiocontrast agents.
http://neonatal.ttuhsc.edu/discus/messages/55/128.html?1051295942

  
 HDCN-- ASK THE PROFESSOR: Contrast Nephropathy
i have "heard" from housestaff that the reason to dialyse someone post procedure is to reduce the dye load/volume and therefore avoid pulmonary edema the dialysis is not necessarily for radiocontrast nephorpathy.i cant seem to find any literature to support this view.
Dialysis treatment probably has worst effects on renal function than radiocontrast, expecially if are used non biocompatible dialysis membranes.
Effects of saline, mannitol, and furosemide on acute decreases in renal function induced by radiocontrast agents.
http://www.hdcn.com/ap/ap607con.htm

  
 Complement Activation-Related Pseudoallergy Caused by Liposomes, Micellar Carriers of Intravenous Drugs, and ...
There is growing awareness that numerous drug-induced immediate hypersensitivity reactions (HSRs) do not fit in Gell and Coombs’ Type I category of drug allergies, characterized by the pivotal pathogenic role of allergen-specific IgE.
Complement Activation-Related Pseudoallergy Caused by Liposomes, Micellar Carriers of Intravenous Drugs, and Radiocontrast Agents
Further issues addressed in the review include animal models, risk factors, laboratory predictive tests, and pharmacological prevention of CARPA.
http://www.begellhouse.com/journals/3667c4ae6e8fd136,2dbee23b005233cf,7665cee60b7f8e89.html

  
 Relationship between the diuretic effect of radiocontrast media and their ability to increase renal vascular resistance ...
The relationship between diuresis and natriuresis induced by radiocontrast
Relationship between the diuretic effect of radiocontrast media and their ability to increase renal vascular resistance
Relationship between the diuretic effect of radiocontrast media and their ability to increase renal vascular resistance -- Morcos et al.
http://bjr.birjournals.org/cgi/content/abstract/68/812/850

  
 Gale Encyclopedia of Medicine: Cardiac catheterization
During this time, the patient may experience a hot, flushed feeling or a quickly passing nausea.
After the catheter is guided into the coronary-artery system, a dye (also called a radiocontrast material) is injected to aid in the identification of any abnormalities of the heart.
Pressure may also be experienced as the catheter travels through the blood vessel.
http://www.findarticles.com/p/articles/mi_g2601/is_0002/ai_2601000264

  
 Potential deleterious effect of furosemide in radiocontrast nephropathy - Wheeless' Textbook of Orthopaedics
Furosemide may be deleterious in the prevention of radiocontrast nephropathy.
Potential deleterious effect of furosemide in radiocontrast nephropathy
Renal failure was associated with weight loss in the furosemide -treated group.
http://www.wheelessonline.com/ortho/potential_deleterious_effect_of_furosemide_in_radiocontrast_nephropathy

  
 Radiocontrast Nephropathy
Despite its effects on dopaminergic receptors, infusion of dopamine has also not been shown to prevent RCN in patients with chronic renal insufficiency.
Most patients who undergo these procedures are not affected.
Radiocontrast nephropathy is the third most common cause of acute renal failure and is also seen in patients undergoing scans which require the use of intravenous radio contrast or angiography dye.
http://www.westsubcardiology.com/pages/cath/radiocontrast.html

  
 Bundesverband Niedergelassener Kardiologen e.V. (BNK)
Within the framework of 3 comparative studies, the influence of viscosity and/or osmolality in intraarterial bolus injections on downstream microcirculation was tested in patients with coronary heart disease.
Optimum Radiocontrast Agent for Outpatient Angiography from the Microcirculatory Point of View
Perfusion of the nailfold capillaries depends significantly on the viscosity, but not the osmolality, of the radiocontrast agent injected in coronary heart disease patients.
http://www.bnk.de/herz/en/1919_2459.htm

  
 Radiocontrast Nephropathy:Increase in Serum Creatine
The 2% rate in the intervention group was confirmed in an open-label follow-up registry.
http://www.annieappleseedproject.org/radnepinserc.html

  
 News - Simultaneous Online Dialysis Does Not Prevent Nephrotoxicity During Radiocontrast Medium Administration
Radiocontrast medium-associated nephrotoxicity is a common cause of acute renal failure that can cause end-stage renal failure in patients with pre-existing chronic renal insufficiency, according to Helga Frank, MD, with the Department of Nephrology at the Friedrich Alexander University Erlangen-Nurnberg, Germany, and colleagues.
Whether simultaneous dialysis can prevent nephrotoxicity in these patients is unclear.
Simultaneous online dialysis appears to have no effect on preventing nephrotoxicity during administration of radiocontrast medium, new research suggests.
http://www.docguide.com/news/content.nsf/news/8525697700573E1885256DB6002D41BD

  
 BioMed Central Abstract Radiocontrast Nephropathy
The risk of developing radiocontrast nephropathy (RCN) is high in patients who are at risk, particularly those patients with diabetes and renal insufficiency.
The development of RCN is associated with a significant increase in in-hospital mortality.
http://www.biomedcentral.com/1523-3839/2/335/abstract

  
 ASHP: Fenoldopam Does Not Protect The Nearly One-Third Of High-Risk Cardiac Catheter Patients Who Get Radiocontrast ...
The study included patients who had a pre-catheterisation serum creatinine of more than 1.5 mg/dL and risk factors for RCN, as well as those with pre-catheterisation serum creatinine of more than 1.7 mg/dL who had no such risk factors.
SAN DIEGO, CA -- June 9, 2003 -- Approximately 29% of high-risk patients undergoing cardiac catheterisation develop radiocontrast nephropathy (RCN) And, one of the agents commonly given to prevent RCN, fenoldopam (Corlopam), is apparently ineffective and is therefore unnecessary, say researchers.
Among these patients, 50% had chronic heart failure, 52% had diabetes mellitus, and 41% were more than 70 years old.
http://www.docguide.com/dg.nsf/PrintPrint/EDB2BC02F513BA7585256D400068F1E9

  
 AW: Avoidance of reactions to radiocontrast media?
Therefore I think that the expression "radiocontrast agent" might point to an agent which gives contrast using x-rays.
I believe they are as they also consider the use on "nonionic dyes" which are frequently used in such studies.
Another example is the adminstering of KI in the case of a nuclear accident with release of radioiodine - much emphasis is laid on persons being allergic to iodine and "elders".
http://www.vanderbilt.edu/radsafe/0312/msg00034.html

  
 Merten, 2004
The Study Patients: patients requiring radiocontrast for angiography, CT or TIPPS with a serum Creatinine of > 97.2mcmol/l and < 707mcmol/l.
The Study :Blinded randomised controlled trial without intention-to-treat analysis.
Control group (n = 68; 59 analysed): received a total of 9 mMol/kg NaCl around the time of imaging
http://www.sicsebm.org.uk/Random/merten.htm

  
 Angiogram - Wikipedia, the free encyclopedia
The most common angiogram performed is to visualize the blood in the coronary arteries.
As blood has the same radiodensity as the surrounding tissues, a radiocontrast agent (which absorbs X-rays) is added to the blood to make angiography visualization possible.
A long, thin, flexible tube called a catheter is used so as to administer the radiocontrast agent at the desired area to be visualized.
http://en.wikipedia.org/wiki/Angiography

  
 Radiocontrast - Wikipedia, the free encyclopedia
Radiocontrast agents (or simply contrast agents) are compounds used to improve the visibility of internal bodily structures in an X-ray image.
Contrast agents (usually based on gadolinium) are also used in MRI (Magnetic Resonance Imaging).
http://en.wikipedia.org/wiki/Contrast_media

  
 Radiology - Wikipedia, the free encyclopedia
Often, chemicals are injected, swallowed or otherwise administered into the body of the patient to help delineate certain parts of the body such as the blood vessels and gastrointestinal tract.
Fluoroscopy, angiography and barium contrast studies are special applications of X-ray imaging, where an X-ray video camera allows the imaging of structures in motion or augmented with a radiocontrast agent.
http://en.wikipedia.org/wiki/Radiology

  
 Health Encyclopedia
Serum levels of the medication may be checked regularly.
Adequate hydration after radiocontrast dyes may allow their excretion and reduce the risk of kidney damage.
http://healthcontent.centralbap.com/adamcontent/ency/article/000512.asp

  
 THE MERCK MANUAL, Sec. 17, Ch. 214, Clinical Evaluation Of Genitourinary Disorders
Additionally, retrograde evaluation may be indicated to assess the degree, type, cause, and length of ureteral obstruction or when the patient is allergic to IV radiocontrast.
( Caution: Acute renal failure occasionally occurs [incidence < 0.5%] after radiocontrast procedures in low-risk patients.
Disadvantages are potential infection, distortion of the calyces by overdistention, backflow phenomena that obscure detail, acute ureteral edema and secondary stricture formation, and the need for anesthesia.
http://www.merck.com/mrkshared/mmanual/section17/chapter214/214a.jsp

  
 FlowMedica, Inc.
The condition occurs when patients’ kidneys are unable to process the iodinated radiocontrast media administered during coronary interventional and diagnostic procedures.
Consequently, kidney function is compromised and waste products build up in the bloodstream.
http://www.flowmedica.com/rcn.htm

  
 U.S. Pregrant 20040167415 - Method and system for prevention of radiocontrast nephropathy
Method and system for prevention of radiocontrast nephropathy
U.S. Pregrant 20040167415 - Method and system for prevention of radiocontrast nephropathy
http://cxp.paterra.com/uspregrant20040167415.html

  
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PREVENTION AND TREATMENT MODALITIES OF RADIOCONTRAST-INDUCED NEPHROPATHY: Modalities of prevention and treatment of radiocontrast-induced nephropathy are as follows: adequate hydration of patients, appropriate application of diuretics, calcium channel blockers nonionizing radiocontrast and preventive haemodialysis.
COURSE OF RADIOCONTRAST-INDUCED NEPHROPATHY: The clinical course of radiocontrast-induced nephropathy may manifest from asymptomatic picture to development of oliguric form of acute renal failure.
CONCLUSION: The problem is particularly important because there is a large number of patients in whom there is a risk of radiocontrast-induced nephropathy and it is necessary to carry out adequate prophylaxis and accurate assessment of kidney function before application of radiocontrast substances.
http://diabetes-2.viagenbio.com/diabetes-research-abs3.jv1219.html

  
 Avoidance of reactions to radiocontrast media?
A note was posted to Medscape recently to the following relevant question which may be of interest to some involved in medical HP or who might be involved in evaluating a procedure they or a family member may need to receive.
This reaction is not believed to be of an Ig E-mediated cause.
Stewart Farber ===================== Allergic Reactions to Radiocontrast Media Question: What are the guidelines on the incidence and avoidance of reactions to radiocontrast media?
http://www.vanderbilt.edu/radsafe/0312/msg00029.html

  
 News - Acetylcysteine Prevents Renal Problems After Angiography: Presented at ACC
Researchers from the Geisinger Medical Center, in Danville, Pennsylvania, also demonstrated that the benefit was greater in patients with baseline serum creatinine levels that were 2 mg/dL or greater.
Transient renal insufficiency after exposure to radiocontrast agents has been well described, and the only preventive measure that has been validated in the setting of coronary angiography is pre- and post-procedure hydration, Dr. Elie Mouhayar explained.
Acetylcysteine has been shown to have clinical benefit in preventing radiocontrast-induced nephropathy if administered orally for 24 hours before and after computed tomography scan studies.
http://www.docguide.com/news/content.nsf/news/8525697700573E1885256B80004AFC40

  
 Subject Consultant Review
This concise review summarizes recent data concerning the use of acetacolamide and the effect of different contrast agents.
Since several years there is renewed interest in the prevention of radiocontrast nephropathy.
http://www.ndt-educational.org/eckardt37.asp

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