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Topic: Pulmonary vascular resistance


  
 Postoperative
Sympathetic nerve stimulation increases pulmonary vascular resistance, and is responsible for the reflex sympathetic pulmonary vasoconstriction that follows distention of the main pulmonary artery.
In the face of increased pulmonary vascular resistance and systemic hypotension, cerebral perfusion pressure may decline to a level that may lead to neurologic ischemia and injury.
This latter reflex is particularly strong in the muscularized resistance vessels of the pulmonary circulation of an infant when compared to adults, and may have significant pathophysiological implications in pulmonary hypertensive crises.
http://www.pediheart.org/practitioners/principals/postop.htm   (6892 words)

  
 Pulmonary Vascular Disease
Pulmonary thromboendarterectomy is a surgical technique for treating pulmonary hypertension caused by unresolved pulmonary embolism.
CONCLUSIONS: Preexisting increased pulmonary blood flow alters the response of the pulmonary circulation to hypothermic CPB; the increase in pulmonary vascular resistance induced by CPB is augmented in lambs with increased pulmonary blood flow.
The purpose of the present study was threefold: to characterize the changes in pulmonary vascular resistance and vascular reactivity induced by hypothermic CPB; to investigate the effects of preexisting increased pulmonary blood flow on these changes; and to better define the role of endothelin 1 in the pathogenesis of post-CPB pulmonary hypertension.
http://www.pediheart.org/searches/topic/pvod.htm   (18455 words)

  
 PERSISTENT PULMONARY HYPERTENSION OF THE NEWBORN
Abnormal responsiveness of the pulmonary vasculature to hypoxia with an inability to relax after the stimulus for vasoconstriction is removed, i.e.
Persistent pulmonary hypertension of the newborn is a cardiopulmonary disorder characterized by systemic arterial hypoxemia secondary to elevated pulmonary vascular resistance with resultant shunting of pulmonary blood flow to the systemic circulation.
Persistent pulmonary hypertension of the newborn (PPHN) is the result of elevated pulmonary vascular resistance to the point that venous blood is diverted to some degree through fetal channels (i.
http://neonatal.peds.washington.edu/NICU-WEB/pphn.stm   (3559 words)

  
 Control and Management of Pulmonary Vascular Tone in the Newborn. Child's Doctor Spring 2000.
Pulmonary hypertension frequently occurs in infants with congenital diaphragmatic hernia.
This may in part be due to the lack of echocardiographic evidence for pulmonary hypertension in several of the infants studied.
Vasoconstriction in response to low oxygen tension is at least partially responsible for the high pulmonary vascular resistance of the fetus.
http://www.childsdoc.org/spring2000/pulvasctone.asp   (4083 words)

  
 NEJM -- Reduction in Pulmonary Vascular Resistance with Long-Term Epoprostenol (Prostacyclin) Therapy in Primary ...
AGUILAR, R. Epoprostenol (Prostacyclin) Therapy in HIV-associated Pulmonary Hypertension.
Reduction in Pulmonary Vascular Resistance with Long-Term Epoprostenol (Prostacyclin) Therapy in Primary Pulmonary Hypertension
NEJM -- Reduction in Pulmonary Vascular Resistance with Long-Term Epoprostenol (Prostacyclin) Therapy in Primary Pulmonary Hypertension
http://content.nejm.org/cgi/content/abstract/338/5/273   (3346 words)

  
 Pulmonary hypertension - definition of Pulmonary hypertension in Encyclopedia
Pulmonary Hypertension (http://www.hopkins-lungs.org/programs/ph/) from the Division of Pulmonary and Critical Care Medicine of the Johns Hopkins School of Medicine (http://www.hopkins-lungs.org/).
Definite pulmonary hypertension is present when mean pressures at rest exceed 25 mmHg.
Expression of Human Herpesvirus 8 in Primary Pulmonary Hypertension.
http://encyclopedia.laborlawtalk.com/Pulmonary_hypertension   (1056 words)

  
 All-Net ventricular septal defects
In this situation, the primary determinant of VSD shunt flow is the pulmonary vascular resistance.
When the pulmonary vascular resistance starts to rise and/or the total pulmonic blood flow is greater than twice the systemic flow, the defect will be need to be closed surgically.
The primary physiologic variable that determines the physiologic state of the patent is the nature of the pulmonary vascular resistance.
http://pedsccm.wustl.edu/All-Net/english/cardpage/operate/vsd/VSD-KUMC.html   (1288 words)

  
 Intravenous Sildenafil Lowers Pulmonary Vascular Resistance in a Model of Neonatal Pulmonary Hypertension -- ...
to intravenous vasodilator therapy in patients with pulmonary
In the control group, there were no further changes in pulmonary and systemic hemodynamics between 120 and 240 minutes.
Current management of PPHN includes therapies that are targeted at lowering the pulmonary vascular resistance including inhaled
http://ajrccm.atsjournals.org/cgi/content/full/165/8/1098   (3621 words)

  
 Vascular resistance
Vascular resistance is a term used to define the resistance to flow that must be overcome to push blood through the circulatory system.
The basic tenet of calculating resistance is that flow is equal to driving pressure divided by resistance.
The major determinant of vascular resistance is small arteriolar (known as resistance arterioles) tone.
http://www.sciencedaily.com/encyclopedia/vascular_resistance   (576 words)

  
 Effects of anaphylaxis mediators on partitioned pulmonary vascular resistance during ragweed shock in dogs -- Mink et ...
All vascular catheters were placed under sterile conditions.
In most studies, the effects of mediators on PVR have been examined under nonanaphylactic conditions (1, 2, 4, 20,
calculation of segmental vascular resistances in the various conditions.
http://www.jap.org/cgi/content/full/84/3/782   (4792 words)

  
 Ventilation above Closing Volume Reduces Pulmonary Vascular Resistance Hysteresis -- CREAMER et al. 158 (4): 1114 -- ...
Pulmonary vascular resistance hysteresis response to changes in lung volume.
behaviors of subpopulations of the pulmonary vascular bed, like
Effect of surface tension on circulation in the excised lungs of dogs.
http://www.ajrccm.org/cgi/content/full/158/4/1114   (4014 words)

  
 Critical Care Full text Levosimendan reduces pulmonary vascular resistance: clinical echocardiographic study
Levosimendan reduces pulmonary vascular resistance: clinical echocardiographic study
Values are expressed as the mean ± SD.
http://ccforum.com/content/8/S1/P90   (423 words)

  
 eMedicine - Congestive Heart Failure and Pulmonary Edema : Article by Shamai Grossman, MD, MS
Topical nitrate therapy is reasonable in a patient presenting with class I to II CHF.
Lin M: Reappraisal of continuous positive airway pressure therapy in acute cardiogenic pulmonary edema.
As a result, they increase cardiac contractility and reduce vascular tone by vasodilatation.
http://www.emedicine.com/emerg/topic108.htm   (5688 words)

  
 ipedia.com: Ductus arteriosus Article
Decreased pulmonary vascular resistance increases pulmonary blood flow while pulmonary vascular pressure falls below aortic pressure.
Failure of a child's DA to close after birth results in a condition called patent ductus arteriosus.
During fetal development, this shunt protects the lungs from being overworked and allows the right ventricle to strengthen.
http://www.ipedia.com/ductus_arteriosus.html   (298 words)

  
 Relationship Between Interleukin-6 Production in the Lungs and Pulmonary Vascular Resistance in Patients With ...
vascular tone and resistance in patients with pulmonary hypertension
In contrast, the mean pulmonary arterial pressure, pulmonary
produced in the pulmonary circulation and investigated the relationship
http://www.chestjournal.org/cgi/content/full/121/4/1195   (3440 words)

  
 N-acetylcysteine - Vitacost
There are also indications that cardiopulmonary physiology is favorably affected by such therapy including improvements in chest radiograph edema scores, pulmonary vascular resistance, static compliance, oxygen delivery, and oxygen consumption.
Although many antioxidants have been investigated in in vitro systems and in animal models, only some are at the developmental stage, or safe for clinical trials.
We hypothesized that the partial benefit derived from granulocyte depletion was due to the effective removal of a major source of oxygen radicals.
http://www.vitacost.com/science/medstudies.cfm?litid=23   (1785 words)

  
 Atrial septal defect
This involves placing a catheter in the venous system of the heart andmeasuring pressures and oxygen saturations in the SVC, IVC, rightatrium, right ventricle, pulmonary artery, and in the wedge position.
The right ventricle will be forcedto generate higher pressures to try to overcome the pulmonary hypertension.
Those that perform the procedure believe that they arepreventing long-term deterioration in cardiac function and preventing progression of pulmonary hypertension.
http://www.therfcc.org/atrial-septal-defect-8111.html   (2329 words)

  
 Pulmonary Vascular Resistance
Your PVR is equal to about 70.1 (dyne*sec)/cm5.
I also do not have any lung disease that could account for the pulmonary pressures.
Recently, I had a right heart catheterization because I had high pulmonary artery pressures with a drop in pulse oximetry with a stress echocardiogram.
http://www.medhelp.org/forums/cardio/messages/34576a.html   (1157 words)

  
 AllRefer Health - Changes in the Newborn at Birth (Birth - Changes in the Newborn)
Once the cord is cut and the baby takes his first breath, a number of changes occur in the newborn's vascular system.
There are some structures in the fetal vascular system that make this type of blood movement possible:
There is also an increase in the blood flow resistance of the body's vessels.
http://health.allrefer.com/health/changes-in-the-newborn-at-birth-info.html   (852 words)

  
 THE MERCK MANUAL, Sec. 19, Ch. 261, Congenital Anomalies
No specific therapies for pulmonary vascular disease exist, although research is ongoing for the use of such drugs as prostacyclin.
As pulmonary vascular resistance approaches and equals systemic vascular resistance, left-to-right shunting is decreased, and right-to-left shunting leads to systemic desaturation and visible cyanosis.
Pulmonary vascular disease may be a limiting factor in the care of infants and children with congenital defects (eg, ventricular septal defect, atrioventricular canal defect, truncus arteriosus) in which high-pressured (ventricular, aortic-pulmonary) shunts occur and may exist alone as primary pulmonary hypertension.
http://www.merck.com/pubs/mmanual/section19/chapter261/261c.htm   (222 words)

  
 EVALUATION AND MANAGEMENT OF CHILDREN WITH END-STAGE CARDIOMYOPATHY AND ELEVATED PULMONARY VASCULAR RESISTANCE
The capillary wedge pressure, systemic vascular resistance, and heart rate did not change significantly.
We hypothesized that the combination of a phosphodiesterase inhibitor and a ß-agonist may provide cardiac support and pulmonary vasodilation in such patients, and that the response to the therapy may help to differentiate patients requiring heart and lung transplant (HLT) from those who could do well with HT alone.
We conclude that therapy with milrinone and dobutamine has beneficial effects on both cardiac performance and pulmonary vascular resistance in children with CM and elevated Rp, and allow successful HT in some children who might otherwise be considered inappropriate candidates.
http://www.a-s-t.org/library/abstracts99/713.htm   (339 words)

  
 Pulmonary hypertension: treatment of high pulmonary vascular resistance
This drug, which blocks endothelin receptors, is currently the most promising approach.
This presumably accounts for its ability to reduce pulmonary pressure and vascular resistance in patients with pulmonary hypertension.
Multi-centre studies have compared the effect of bosentan (125-250 mg twice daily) or placebo added to conventional therapy in patients with severe pulmonary hypertension.
http://www.tg.com.au/etg_demo/tgc/cvg/77.htm   (414 words)

  
 Critical Care Full text Nitric oxide improves pulmonary vascular resistance but not oxygenation in ARDS, heart ...
Data were collected prior to NO therapy, 24 and 48 h after NO was initiated.
In this study, the only significant effect of NO was on the PVR in patients considered as a whole and in the pulmonary hypertension subgroup.
We attribute this lack of response in oxygenation to severe underlying pulmonary condition as well as other comorbid illnesses.
http://ccforum.com/content/2/S1/P114   (498 words)

  
 Pulmonary vascular resistance
Pulmonary Embolism Article by Craig Feied, MD, detailing the background, diagnosis, and treatment of pulmonary embolism.
Best Practice Medicine - Pulmonary Hypertension Praxis.md's guide to the background, diagnosis, treatment, and prognosis of this disease.
American Heart Association: Pulmonary Hypertension Brief description of the cause and treatment of this disease.
http://www.serebella.com/encyclopedia/article-Pulmonary_vascular_resistance.html   (280 words)

  
 CHEST: Pulmonary vascular resistance in emphysema
We speculated that this group consists of subjects with the clinical and radiographic features ascribed to type A chronic obstructive pulmonary disease (COPD-A).[6] Such patients have less severe disturbances in [unkeyable]A/[unkeyable].
To assess the hemodynamic effects of pulmonary microvasculature disruption in emphysema, we examined resting pulmonary hemodynamics and lung function in 12 carefully identified patients with type A chronic obstructive pulmonary disease.
Respiratory failure with reversible hypertension may supervene as the result of acute respiratory infection and/or respiratory muscle failure, but an irreversible and progressive component of increased pulmonary vascular resistance probably results from ongoing anatomic restriction of the bed.
http://www.findarticles.com/p/articles/mi_m0984/is_n3_v105/ai_14998952   (885 words)

  
 Plasma Monocyte Chemoattractant Protein-1 and Pulmonary Vascular Resistance in Chronic Thromboembolic Pulmonary ...
Association of clinical features with HLA in chronic pulmonary thromboembolism
Plasma Monocyte Chemoattractant Protein-1 and Pulmonary Vascular Resistance in Chronic Thromboembolic Pulmonary Hypertension
The pathogenesis of severe pulmonary hypertension seems to be related to inflammatory response in diseased sites.
http://ajrccm.atsjournals.org/cgi/content/abstract/164/2/319   (441 words)

  
 Heart Transplantation, Cincinnati Children's Hospital Medical Center
Temporary right ventricular dysfunction may occur secondary to elevations in pulmonary vascular resistance that many recipients may have as a result of longstanding heart failure.
If the pulmonary resistance is significantly elevated or the heart function too poor on its own, patients may remain on intravenous medications in the hospital while awaiting transplantation.
Mechanical ventricular support may also be employed to support a patient awaiting transplantation.
http://www.cincinnatichildrens.org/health/info/heart/procedure/transplant.htm   (1207 words)

  
 Basal Pulmonary Vascular Resistance and Nitric Oxide Responsiveness Late After Fontan-Type Operation -- Khambadkone et ...
Basal Pulmonary Vascular Resistance and Nitric Oxide Responsiveness Late After Fontan-Type Operation -- Khambadkone et al.
http://circ.ahajournals.org/cgi/reprint/107/25/3204   (16 words)

  
 Periodic Table
Noninvasive estimation of pulmonary vascular resistance by stroke index measuring with an inert gas rebreathing technique.
Improved arc stability with [O.sub.2] dose to inert gas: improved arc stability and hence weld quality and productivity are achieved by the addition of around 0.03% of oxygen to the inert shielding gas when arc welding aluminium.(FABRICATION) (Aluminium International Today)
http://www.infoplease.com/periodictable.php?group=I   (159 words)

  
 acid-base indicators on Encyclopedia.com
Using Acid-Base Reagent Problems as a High School Science Research Activity.(student experiment for testing the influence of chlorine on pH indicator)
The influence of respiratory acid-base status on adult pulmonary vascular resistance before and after cardiopulmonary bypass.
Five rules, and how they simplify complex cases.
http://www.encyclopedia.com/html/X/X-acidbase.asp   (329 words)

  
 Pulmonary Vascular Resistance (PVR)
PVR = [(Mean PA pressure - PCWP) x 80] / CO home
http://mobile.neulabs.com/labstudies/pvr.asp   (13 words)

  
 Pulmonary Vascular Resistance Calculator
PVR = 80 x (MPAP - PCWP) / CO
http://www.medstudents.com.br/calculat/pvr.htm   (9 words)

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