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Topic: Prolactinoma



  
 Prolactinoma - New Treatments, January 15, 2005
Because of the excellent therapeutic responses to transsphenoidal surgery and medical therapy, radiotherapy is generally not considered as a primary treatment for prolactinomas.
Although such approval for the treatment of hyperprolactinemia is lacking, there is considerable experience with its use in patients with prolactinoma, and such use is well-documented in the literature.
Although the emphasis in this article is on medical therapy, various treatment modalities are available for prolactinomas.
http://www.ccspublishing.com/journals5a/prolactinomas.htm

  
 PROLACTINOMA
Most prolactinomas are completely curable with medication or surgery.
If medical therapy is not tolerated or fails to control the growth of the prolactinoma, then surgery is required.
One or two individuals in 10,000 will have a prolactinoma.
http://www.apma-nc.com/PatientEducation/prolactinoma.htm

  
 Treatment of Prolactinomas
These are not all of the papers published on the subject, they have been selected to give the prolactinoma patient and/or his or her family (or even general practitioner) an overview of treatment by medication and surgery.
This web site will be of interest to prolactinoma patients, their families and doctors, and to medical students.
I am not a doctor, and have no medical training, but somebody close to me, a family member, has a prolactinoma and polycystic ovaries so I developed an interest in finding and reading medical research on the subject.
http://ca.geocities.com/chris_anthistle/prolactinoma/index.html

  
 dreddyclinic.com - Prolactinoma
If drug therapy for the treatment of prolactinoma is unsuccessful or not tolerated, surgery may be an option for the removal of a pituitary tumor.
In addition, your doctor may refer you for more extensive testing with a doctor who specializes in treating disorders of the endocrine system (endocrinologist).
Treatment for prolactinoma consists of two main therapies:
http://www.dreddyclinic.com/findinformation/pp/prolactinoma.htm

  
 The Pituitary Foundation Patient leaflet Prolactinoma
The chances of this happening depend on the size of the prolactinoma; if it is very small or quite large, then the surgical results may not be so good and you may need bromocriptine anyway.
This is an important point because may women with a prolactinoma will be taking the drug with the specific aim of falling pregnant.
Again, even these prolactinomas can usually be treated effectively with tablets, rather than surgery.
http://www.pituitary.org.uk/resources/prolactinoma.htm

  
 The High Mobility Group A2 Gene Is Amplified and Overexpressed in Human Prolactinomas -- Finelli et al. 62 (8): 2398 -- ...
HMGA2 locus in most of the human prolactinomas analyzed.
a critical role of HMGA2 overexpression in human prolactinomas.
HMGA2 locus, we demonstrated amplification of HMGA2 in most
http://cancerres.aacrjournals.org/cgi/content/full/62/8/2398

  
 In Hyperprolactinemia, Testing for Macroprolactin Is Essential -- Fahie-Wilson 49 (9): 1434 -- Clinical Chemistry
Is idiopathic hyperprolactinaemia a transitional stage toward prolactinoma?.
of pituitary imaging techniques in the confirmation of prolactinoma
To summarize, there is a substantial body of evidence indicating
http://www.clinchem.org/cgi/content/full/49/9/1434

  
 News - Case Report of Post-Hemorrhage Prolactinoma Regrowth That Was Resistant to Dopamine Agonists
WASHINGTON, DC -- May 24, 2005 -- "Prolactinomas can potentially regrow and become unresponsive to dopamine agonists," according to Khurshid Ahmad Khan, MD, a fellow in clinical endocrinology at the University of Missouri in Columbia, Missouri, United States.
However, during the subsequent 18 months, hyperprolactinemia gradually recurred despite continued therapy with bromocriptine 10 to 15 mg/d, but without associated enlargement of the sellar mass, visual field changes, or headache.
Prolactinoma resistance to dopamine agonist therapy is reported at 5% to 18%, and options are to switch from one dopamine agonist to another or raise the dose.
http://www.docguide.com/news/content.nsf/news/8525697700573E188525700B006676F4

  
 Prolactinoma - Wikipedia, the free encyclopedia
Similarly, post-menopausal estrogen replacement is safe in patients with prolactinoma treated with medical therapy or surgery.
This type of drug is called a dopamine agonist.
Bromocriptine or cabergoline treatment may be renewed and additional treatment may be required if the patient develops symptoms from growth of the tumor during pregnancy.
http://en.wikipedia.org/wiki/Prolactinoma

  
 1999 GuestBook for Pituitary Tumor Guestbook at Massachusetts General Hospital/Harvard
Thank you all, and if anyone needs information about prolactinoma and surgery i will gladly help.
I posted this about a year ago and got no responses.
I have taken both medications to treat my prolactinoma.
http://pituitary.mgh.harvard.edu/Guest/Guest99.htm

  
 Prolactinoma and Meniere's disease
Systematic determination of prolactin might be sensible before opting for surgery until these findings are confirmed.
Prolactinoma in some Ménière's patients - is stress involved?
Hyperprolactinaemia was found preoperatively in 14/42 patients with Ménière's disease, and in six who were investigated prolactinoma was found.
http://www.jr2.ox.ac.uk/bandolier/booth/ENT/prolmen.html

  
 "MacroLH": Anomalous Molecular Form That Behaves as a Complex of Luteinizing Hormone (LH) and IgG in a Patient with ...
Some forms of big-big prolactin behave as complex of monomeric prolactin with an immunoglobulin G in patients with macroprolactin or prolactinoma.
Cavaco B, Leite V, Santos AM, Arranhado E, Sobrinho LG.
http://www.clinchem.org/cgi/content/full/49/12/2104

  
 Cabergoline - A New Dopamine Agonist for the Therapy of Prolactinoma - Neuroendocrine Clinical Center & Pituitary ...
In summary, cabergoline appears to be a more effective and better tolerated dopamine agonist in the therapy of prolactinomas.
For this reason all patients enrolled are required to have had no prior therapy with any dopamine agonists, in order to avoid studying patients who have already experienced some tumor shrinkage with other agents.
Cabergoline - A New Dopamine Agonist for the Therapy of Prolactinoma - Neuroendocrine Clinical Center and Pituitary Tumor Center at MGH/Harvard
http://pituitary.mgh.harvard.edu/e-s-962.htm

  
 Statistics by Country for Prolactinoma - WrongDiagnosis.com
As discussed above, these incidence extrapolations for Prolactinoma are only estimates and may have limited relevance to the actual incidence of Prolactinoma in any region:
As such, these extrapolations may be highly inaccurate (especially for developing or third-world countries) and only give a general indication (or even a meaningless indication) as to the actual prevalence or incidence of Prolactinoma in that region.
The term 'incidence' of Prolactinoma means the annual diagnosis rate, or the number of new cases of Prolactinoma diagnosed each year (i.e.
http://www.wrongdiagnosis.com/p/prolactinoma/stats-country_printer.htm

  
 Galactorrhoea and pituitary mass: a typical prolactinoma? -- Brändle and Schmid 76 (894): 232 -- Postgraduate ...
The presentation of our patient with galactorrhoea, hyperprolactinaemia, and a pituitary mass suggested, at first glance,
patients with pituitary enlargement before the diagnosis of prolactinoma
Profound biochemical hypothyroidism may exist in apparently healthy individuals with minimal clinical evidence of hypothyroidism.
http://www.postgradmedj.com/cgi/content/full/76/894/232

  
 The Environmental Estrogen Bisphenol A Stimulates Prolactin Release in Vitro and in Vivo -- Steinmetz et al. 138 (5): ...
PRL levels and does not readily form prolactinomas ( 21, 22).
estrogens may stimulate incipient prolactinomas to grow or are
BPA both in vitro and in an animal model.
http://endo.endojournals.org/cgi/content/full/138/5/1780

  
 Diagnosis and management of hyperprolactinemia -- Serri et al. 169 (6): 575 -- Canadian Medical Association Journal
one study, the apparent surgical cure rate for prolactinomas,
Passos VQ, Souza JJ, Musolino NR, Bronstein MD. Long-term follow-up of prolactinomas: normoprolactinemia after bromocriptine withdrawal.
Jeffcoate WJ, Pound N, Sturrock NDC, Lambourne J. Long-term follow-up of patients with hyperprolactinaemia.
http://www.cmaj.ca/cgi/content/full/169/6/575

  
 http://members.aol.com/Page8.html
My steroids seem to do that a lot.,I take tylenol three for my headaches.
Melinda is a very popular person on this website.....largely due to the fact that she conceived and delivered a healthy and beautiful baby while undergoing treatment for her prolactinoma.
Parlodel for Prolactinoma, although I've taken myself off for awhile for fear of becoming immune to the drug.
http://members.aol.com/tomajestic/Page8.html

  
 Involvement of bone morphogenetic protein 4 (BMP-4) in pituitary prolactinoma pathogenesis through a Smad/estrogen ...
prolactinomas, whereas BMP-4 has no action in other human pituitary
Involvement of bone morphogenetic protein 4 (BMP-4) in pituitary prolactinoma pathogenesis through a Smad/estrogen receptor crosstalk
Involvement of bone morphogenetic protein 4 (BMP-4) in pituitary prolactinoma pathogenesis through a Smad/estrogen receptor crosstalk -- Páez-Pereda et al.
http://www.pnas.org/cgi/content/abstract/100/3/1034

  
 Functional role of estrogen in pituitary tumor pathogenesis -- Heaney et al. 109 (2): 277 -- Journal of Clinical ...
development or to increase individual susceptibility to prolactinoma
The Novel Use of Very High Doses of Cabergoline and a Combination of Testosterone and an Aromatase Inhibitor in the Treatment of a Giant Prolactinoma
) and fibroblast growth factor (bFGF) expression in prolactinoma pathogenesis.
http://www.jci.org/cgi/content/full/109/2/277

  
 Effect of Risperidone on Prolactinoma Growth in a Psychotic Woman -- Pal and Sarino 62 (5): 736 -- Psychosomatic ...
prolactinoma while being treated with thioridazine ( 5).
METHODS: Although the patient had been treated with a high dose
The clinical effects of increased prolactin levels are
http://www.psychosomaticmedicine.org/cgi/content/full/62/5/736

  
 Neurological Society of India
The residual lesion, if prolactinoma, can be treated with medication or radiosurgery or expectant follow up, depending on what the patient can afford.
However, I feel that this is most likely a prolactinoma.
However, if this is not, there is a fair chance of recurrence and the patient must be followed up carefully.
http://www.neurosocietyindia.org/indNSICommentsCase2.htm

  
 Health Encyclopedia
See your health care provider if symptoms suggestive of prolactinoma develop.
If you have had a prolactinoma in the past, call your health care provider if you experience recurrence of the symptoms.
By contrast, prolactinomas in men occur in older patients and can grow to a large size before any symptoms occur.
http://healthcontent.baptistnortheast.com/adamcontent/ency/article/000336.asp

  
 OHSU Pituitary Unit - Prolactinoma
Fortunately, in most cases a prolactinoma can be treated with a class of medications called dopamine agonists.
In some cases, the prolactinoma will not respond to medication or the patient is intolerant to the medication's side effects; in these cases surgery may be indicated if mass effects of the tumor are a concern.
As mentioned above, most prolactinomas are sensitive to dopamine agonist treatment.
http://www.ohsupituitary.com/patients/prolac.asp

  
 UMHS Neurosurgery Pituitary Conditions & Treatments
Lower prolactin levels may be seen in patients with small prolactinomas or in those with other conditions (see above).
Small prolactinomas in young women may not require specific treatment unless infertility or galactorrhea are of concern.
Larger tumors in women and tumors of any size in men are best treated with medications: Bromocriptine (Parlodel) Pergolide (Permax) or cabergoline (Dostinex) are used for this purpose.
http://www.med.umich.edu/neurosurgery/pituitary/conditions.htm

  
 Misdiagnosis of Medication Causes of Prolactinoma - CureResearch.com
About medication causes: Another misdiagnosis possibility is that a particular medication or substance may be the real cause of the disease.
Side effects of medications, or exposure to toxins, chemicals, or other substances may cause a symptom or condition.
Misdiagnosis of Medication Causes of Prolactinoma - CureResearch.com
http://www.cureresearch.com/p/prolactinoma/medic_printer.htm

  
 UpToDate Patient information: Lactotroph adenomas (prolactinomas)
— Bromocriptine has been used for 20 years to treat prolactinomas.
When cabergoline treatment is stopped, high prolactin levels may recur, but in one study, no tumor regrowth was seen.
While it is usually very effective in lowering blood prolactin levels, it can cause side effects, including dizziness, nausea, and nasal stuffiness.
http://patients.uptodate.com/topic.asp?file=endo_hor/8753

  
 Get prolactinoma results and information
Learn more about this difficult to spell medical condition, health related phrase or medication.
Get more information about prolactinoma at our site.
Thank you for visiting and searching for prolactinoma at our site.
http://www.popular-spelling-errors.com/prescriptions/prolactinoma.html

  
 Re: Pituitary Tumors (Prolactinoma)
Also I am looking for anyone else : : on a new, experimental drug called Norprolac : Hello : I don't know if it's experimental in the U.S.,but here in the Netherlands Norprolac was given to my already 3.5 years ago for the treatment of my prolactinoma.
I don't know if it's experimental in the U.S.,but here in the Netherlands Norprolac was given to my already 3.5 years ago for the treatment of my prolactinoma.
Since then i'm feeling much better,and my menstrual cyclus came back after using it for 2 months.And my bloodresults are ok : untill now.(i didn't have surgery because they wanted to try this drug first.) : On October 9th I wil have another MRI-scan since the diagnosis,and this will show if's has shrinked too.
http://www.healthboards.com/immune-disorders/140.html

  
 Nerve Growth Factor Regulates Dopamine D2 Receptor Expression in Prolactinoma Cell Lines via p75NGFR-Mediated ...
The results of a representative experiment are shown.
In this study we used two previously characterized prolactinoma
This conclusion is further supported by the finding
http://mend.endojournals.org/cgi/content/full/16/2/353

  
 DOSTINEX - The Sex Drug (Cabergoline/Cabaser)
The beginning of treatment, mild side-effects were recorded in two patients after Caberoline usage compared to five Bromocriptine patients who suffered mild-to-moderate side-effects.
Treatment with Cabergoline (Dostinex) normalized prolactin in levels, improving gonadal and sexual function and fertility males with prolactinoma, earlier than did Bromocriptine treatment.
Men with high levels of prolactin such as those that suffer from prolactinoma have no sex drive.
http://www.buy-dostinex.com

  
 Prolactinoma Credits
Prolactinoma was written by Michael O. Thorner, M.B., D.Sc., Kenneth R. Crispell Professor of Medicine and Chief of Endocrinology and Metabolism, University of Virginia Health Sciences Center, Charlottesville; and edited by Shereen Ezzat, M.D., Assistant Professor of Medicine, University of Toronto.
http://www.niddk.nih.gov/health/endo/pubs/prolact/credits.htm

  
 prolactinoma, & drug parlodel
would be curious what your symtoms are from the condition Prolactinoma (when you produce a higher level of prolactin, usally from a tumor on the putitary gland) and your reaction to parlodel
http://www.dr-bob.org/babble/19990201/msgs/3000.html

  
 prolactinoma and hypothyroidism
My dh has a prolactinoma (when discovered his prolactin level was over 700) but, he has been able to treat it with bromocriptine (5mg a day) for 4 years now.
He was also diagnosed with hypothyroidism and takes levothroid.
http://www.vegsource.com/talk/health/messages/18474.html

  
 Untitled
This web page was designed for those who are seeking information about Prolactinoma.
Considering that Prolactinoma has an effect on one's nutrition, this web site provides tips on how to best control the effects.
http://prolactandnutrition.tripod.com

  
 Best Practice No 170: Investigation of infertility with the emphasis on laboratory testing and with reference to ...
Is idiopathic hyperprolactinemia a transient stage towards prolactinoma?
The value of functional tests in diagnosis of prolactinoma.
(such as, pregnancy) or may indicate pituitary prolactinoma,
http://jcp.bmjjournals.com/cgi/content/full/56/4/261

  
 The lipoprotein profile of women with hyperprolactinaemic amenorrhoea -- Fahy et al. 14 (2): 285 -- Human Reproduction
Lipoprotein and hormonal profile (median values and range) of 15 women with hyperprolactinaemic amenorrhoea compared with 15 normal controls and in a subgroup of women with hyperprolactinaemia before and during bromocriptine therapy
Pelkonen, R., Nikkila, E.A. and Grahne, B. (1982) Serum lipids, postheparin plasma lipase activities and glucose tolerance in patients with prolactinoma.
of 47 women with prolactinomas and 84 normal controls.
http://humrep.oupjournals.org/cgi/content/full/14/2/285

  
 Autocrine/Paracrine Action of Pituitary Vasoactive Intestinal Peptide on Lactotroph Hyperplasia Induced by Estrogen -- ...
Maas DL, Martinson DR, Erdmann MD, Wahle JS, Hagen TC 1995 Dynamics of prolactin secretion from diethylstilbestrol-induced rat prolactinoma tissue in vitro.
Fernández M, Sánchez-Franco F, Palacios N, Sánchez I, Villuendas G, Cacicedo L 2003 Involvement of vasoactive intestinal peptide on insulin-like growth factor I-induced proliferation of rat pituitary lactotropes in primary culture: evidence for an autocrine and/or paracrine regulatory system.
Jakubowski J 1995 Blood supply, blood flow and autoregulation in the adenohypophysis, and altered patterns in oestrogen induced adenomatous hyperplasia.
http://endo.endojournals.org/cgi/content/full/144/10/4403

  
 Multiple Endocrine Neoplasia Type 1 Variant with Frequent Prolactinoma and Rare Gastrinoma -- Hao et al. 89 (8): 3776 ...
Multiple Endocrine Neoplasia Type 1 Variant with Frequent Prolactinoma and Rare Gastrinoma -- Hao et al.
Results in cases from two kindreds were that 93% showed parathyroid
Multiple Endocrine Neoplasia Type 1 Variant with Frequent Prolactinoma and Rare Gastrinoma
http://jcem.endojournals.org/cgi/content/abstract/89/8/3776

  
 Prolactinoma Index of Wake Forest University
For the Noframes version of the prolactinoma Adenoma Index with extensive links on prolactinoma adenomas see
http://www.wfubmc.edu/surg-sci/ns/prolactinoma.html

  
 Prolactinoma
I was diagnosed in August with a Prolactinoma.
If interested, please Contact Member Services for more information.
My fist Endocronogist said not to worry about getting on meds until I want to get pregnant, but my second Endo doc said that I should get on meds to try to get rid of the tumor and to start my periods again.
http://www.suite101.com/discussion.cfm/4509/97287

  
 Leukemia Inhibitory Factor Regulates Prolactin Secretion in Prolactinoma and Lactotroph Cells -- Ben-Shlomo et al. 88 ...
Leukemia Inhibitory Factor Regulates Prolactin Secretion in Prolactinoma and Lactotroph Cells -- Ben-Shlomo et al.
http://jcem.endojournals.org/cgi/reprint/88/2/858

  
 Pituitary Tumor
3/13/2005 8:04 PM How many have had their prolactinoma's removed
6/5/2005 11:08 PM I'm 17 and I have a prolactinoma
http://groups.msn.com/PituitaryTumor/prolactinoma.msnw

  
 MedlinePlus Enciclopedia Médica: Prolactinoma
Ausencia de la menstruación no relacionada con la menopausia
Es posible que sea necesario realizar una cirugía en el caso de un prolactinoma que no se logra controlar con medicamentos y en aquellos pacientes que tienen dificultades para tolerar sus efectos secundarios.
El prolactinoma, también conocido como adenoma de la pituitaria secretante de prolactina, es el tipo de adenoma pituitario más común.
http://www.nlm.nih.gov/medlineplus/spanish/ency/article/000336.htm

  
 Eresalud. PG: Prolactinoma 01
Prolactinoma : Todo lo que necesitabas conocer acerca de el Prolactinoma podrás encontrarlo en esta extensa guía sobre el diagnóstico, síntomas, tratamiento, etc. Se completa la página con una serie de imágenes sonbre pacientes afectados de esta enfermedad.
Resolución mínima de 800x600© Copyright 2002, Caronte Group Network Services
Prolactinoma : Lo más destacado de esta propuesta es un listado de síntomas producidos por el Prolactinoma, tumor benigno de la glándula pituitaria.
http://www.eresalud.com/Estatico/D00/D00/D09/C00000954.html

  
 prolactinoma
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http://www.dreamedicine.com/prolactinoma.html

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