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| | Apoptosis - Wikipedia, the free encyclopedia |
 | | It must be advised, however, that the apoptotic pathways that have been summarily described are subject to regulatory mechanisms, and that there is not a one-to-one relationship between the reception of TNF or FasL and the complete execution of an apoptotic pathway. | | | Beyond the physiological importance, understanding these patterns will be relevant to maintaining the vitality of cells used for cell therapy. | | | This balancing process is part of the homeostasis required by living organisms to maintain their internal states within certain limits. |
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http://en.wikipedia.org/wiki/Apoptosis
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| | Apoptosis in Development |
| | Cell death is currently the subject of considerable research activity. | | | Those that fail to reach the genital ridges are eliminated, presumably because they are deprived of the signal (Steel factor) that is required for their survival in the genital ridges (De Felici and Pesce, 1994). | | | Exploitation of this relationship holds much promise for therapeutic control of diseases such as cancer. |
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http://www.ucalgary.ca/UofC/eduweb/virtualembryo/death.html
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| | 2004 GRC on Plant Senescence |
| | Our goal is to bring together people using multi disciplinary approaches to the study of senescence and pcd. | | | Gene isolation and molecular analysis have been the focus of much of the work in this area for the last decade but recent exponential advances in genomic analysis have revolutionised this approach. | | | A new session on systems biology will investigate the use of these approaches. |
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http://www.grc.uri.edu/programs/2004/plantsen.htm
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| | Drosophila gene families: Apoptosis - Programmed cell death |
| | Detection of members of the Drosophila defense response pathways (i.e., Toll pathway and imd/TNFα-like pathway) suggests that these pathways or some of their components may play a role in developmentally regulated autophagic cell death. | | | Drosophila encodes a Scythe homolog (accession No. CG7546), suggesting that a similar pathway may exist in flies as well (Vernooy, 2000 and references therein). | | | Drosophila has arguably been in this position for some time. |
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http://www.sdbonline.org/fly/aignfam/apoptoss.htm
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| | Cell Cycle, Senescence, Programmed Cell Death |
| | Stone also observed that salicylate-, jasmonate- and ethylene-dependent pathways contribute to FB1-induced PCD, as indicated by FB1 susceptibility of mutants. | | | However, fbr1 and fbr2 displayed enhanced resistance to an isogenic strain that did not express avrRpt2. | | | Further evidence for PML's role comes from knock-out experiments, which showed that PML-/- fibroblasts lose Ras-induced p53 acetylation, p53-CBP complex stability, and senescence. |
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http://www.hms.harvard.edu/armenise/old_site/4a_cycle.htm
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| | Mitochondrial involvement in tracheary element programmed cell death |
| | While changes in mitochondria morphology and function were observed and suggest a role for mitochondria in TE PCD, the current evidence suggests that cytochrome c release is not sufficient for induction of the PCD in TEs. | | | Our study focuses on the possible role of mitochondria in a plant PCD. | | | The bar represents the standard error of the mean (S.E.M.) of three independent experiments. |
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http://www.nature.com/cdd/journal/v9/n2/full/4400940a.html
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| | Possibilities for Outwitting Programmed Cell Death? |
| | Due to the lack of morphologic evidence, he suggested that further studies of programmed cell death might better rely on biochemical assessments in determining the role of apoptosis in neurodegenerative disease. | | | Commenting on Dr. Burke's presentation, session chair Serge Przedborski, MD, of Columbia University, said, "During development, we have too many cells and we scale down to the number we need for proper brain functioning, and that involves exactly the same mechanism as in animals, for instance, which undergo morphogenesis. | | | Increasing evidence that programmed cell death is the cause of many neurodegenerative disorders—and mounting evidence of the involvement of caspases in this process—have influenced research in the prevention and treatment of Parkinson's disease and other neurologic disorders. |
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http://www.neurologyreviews.com/sep00/nr_sep00_celldeath.html
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| | Genome Biology Full text Cancer and programmed cell death |
| | Two major pathways control the caspase-dependent apoptosis of a cell, namely the extrinsic and intrinsic pathways. | | | The conference included a number of notable presentations on current research into cancer therapeutics. | | | elegans as an experimental model organism and elucidating the genetic pathway for programmed cell death. |
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http://genomebiology.com/2003/4/5/318
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| | Untitled Document |
| | The de-regulation of survival and apoptosis pathways not only contributes to the development of disease, but can also facilitate progression to a disease that is highly drug resistant and very difficult to treat. | | | During this time, Dr. McKenna was also group leader of the Signal Transduction Laboratory. | | | Inhibition of PI3-kinase sensitises HL60 human leukaemia cells to both chemotherapeutic drug and Fas-induced apoptosis. |
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http://www.ccrc.ie/staffsmckenna.htm
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| | Evolution: Programmed Cell Death |
| | Cysteine proteases are involved in a key step in animal PCD pathways, and have recently been demonstrated to also be important in plant PCD (Solomon et al., 1999). | | | Programmed cell death (PCD) is an important mechanism in development and in defense against pathogens in both animals and plants. | | | Thus, nuclear DNA degradation may be a response to mechanical injury and can be mediated by PCD in the hypersensitive response. |
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http://www.geocities.com/we_evolve/Plants/apoptosis.html
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| | Spotlight: Programmed cell death |
| | He figured out how they interact and identified their human counterparts. | | | All three men paved the way for a better understanding of cell processes, which ultimately improve medicine's approach to diseases such as cancer. | | | Brenner's masterstroke was to link the analysis of the nematode's genes with the essential life processes of cell division, differentiation and organ development. |
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http://www.psigate.ac.uk/spotlight/issue7/cell.html
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| | Critical role in programmed cell death identified |
| | Mitochondria are dynamic structures, constantly changing shape, budding and fusing. | | | Hanover, NH--Dartmouth Medical School geneticists have found links in the cell death machinery of worms and mammals, opening new avenues for studying and targeting a process vital to development and implicated in cancer and autoimmune diseases. | | | In spite of its name, programmed cell death, or apoptosis, is essential for life; it's needed for nervous system development and it keeps the body up and running. |
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http://www.eurekalert.org/pub_releases/2005-02/dms-cri021405.php
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| | Andrew A. Marino, Ph.D., J.D. CV |
| | Frequency-specific responses in the human brain caused by electromagnetic fields. | | | Piezoelectricity in bone as a function of age. | | | Effect of hyaluronans on cytokine-induced metalloproteinase activity secreted by synovial lining cells from patients with osteoarthritis. |
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http://www.ortho.lsuhsc.edu/Faculty/Marino/CV.html
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| | Apoptosis (Programmed Cell Death) and Tendinopathy |
| | There is the theory that oxidative stress induces apoptosis, as shown in primary cultured human tendon fibroblasts in vitro. | | | The loss of cells in senescence may be due to this mechanism. | | | Genetic regulation of apoptosis, demonstrated by the discovery of cell death-specific genes and the repression or enhancement of cell death, has proven to be important in conditions such as cancer, Alzheimer's disease, |
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http://www.chiroweb.com/archives/22/07/08.html
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| | Programmed Cell Death |
| | Programmed cell death is the natural, necessary death of individual cells for the good of the organism as a whole. | | | Hermann Steller can study the pathway of programmed cell death in fly cells by altering their environment. | | | Another way in which p53 helps to prevent cancer is through its role in triggering programmed cell death, or apoptosis. |
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http://www.hhmi.org/annual95/b150.html
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| | The Hindu : Genetic regulation of programmed cell death |
| | Research on programmed cell death is intense, including in the field of cancer. | | | Other diseases, like autoimmune conditions and cancer, are characterized by a reduction in cell death, leading to the survival of cells normally destined to die. | | | The vast excess of neuronal cells present during the early stages of brain development is also eliminated by the same mechanism. |
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http://www.hindu.com/thehindu/seta/2002/10/10/stories/2002101000040200.htm
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| | Programmed cell death of plant tracheary elements |
| | Programmed cell death is essential during plant development and in response to environmental ques and pathogen attack. | | | You will see the cells move when the drug is applied, then cytoplasmic streaming stops - but the vacuole does not collapse. | | | As you will see, the death of the cell is not a gradual process, but instead involves a rapid implosion of the large central vacuole and the immediate cessation of cytoplasmic streaming. |
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http://www.bio.unc.edu/faculty/jones/lab/pcd
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| | Cell Death & Differentiation |
| | B-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease | | | CDD is devoted to the cell biology, molecular biology and biochemistry of cell death and disease. |
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http://www.nature.com/cdd
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| | 2005 CSHL Meeting on Programmed Cell Death |
| | • Regulation of Autophagy and Alternative Cell Death Pathways | | | The format of the meeting will include morning and evening sessions consisting of short talks, limited to approximately 15 minutes, principally on unpublished work. | | | The meeting will cover the field of programmed cell death and apoptosis by specific sessions devoted to the topics listed below. |
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http://meetings.cshl.edu/meetings/pcd05.shtml
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| | Apoptosis -Programmed Cell Death: A Role in the Aging Process |
| | In vitro and in vivo data on possible strategies to reduce oxidative stress in lymphocytes from normal and Down syndrome subjects, by using natural compounds and trace elements, are presented. | | | Apoptosis -Programmed Cell Death: A Role in the Aging Process | | | ecent data from our laboratory on the role of DNA damage and pADPRP activation and on the type of cell death induced by OFRs in human lymphocytes are reviewed. |
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http://www.md-phc.com/nutrition/apop.html
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| | CUGI - Publications |
| | In Encyclopedia of Molecular Cell Biology and Molecular Medicine. | | | Exploitation of the daylily petal senescence model as a source for novel proteins that regulate programmed cell death in plants. | | | Comparative sequencing provides insights about the structure and conservation of marsupial and monotreme genomes. |
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http://www.genome.clemson.edu/publications
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| | Programmed Cell Death and Hybrid Incompatibility (ResearchIndex) |
| | @misc{ frank-programmed, author = "S. Frank and C. Barr", title = "Programmed Cell Death and Hybrid Incompatibility", url = "citeseer.ist.psu.edu/frank03programmed.html" } | | | Specialization and Ecological Dynamics - Frank, Amarasekare (1998) |
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http://citeseer.ist.psu.edu/603708.html
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