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| | Pregabalin Clinical Trials |
 | | Pregabalin should be approved for neuropathic pain and anxiety this year, however additional studies will be required in regards to fibromyalgia. | | | Leslie Crofford of the University of Michigan, Ann Arbor, explained that the mechanism of action of pregabalin is “not completely understood,” however researchers believe that it may be effective in treating pain, fatigue and improve sleep quality in patients with fibromyalgia. | | | Patients who were treated with 450 mg/per day were more likely to experience 50% reduction in their pain than those receiving placebo. |
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http://www.fmaware.org/patient/beaware/pregabalin.htm
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| | Pregabalin ?- Cash Cow to Succeed Neurontin ? - BrainTalk Communities |
| | Poster 178 pregabalin pharmacokinetics in patients with chronic pain. | | | Pregabalin was safe and effective in decreasing pain associated with DPN, and also improved mood, sleep disturbance, and quality of life. | | | Pregabalin CL/F is related to CL(cr); this relationship was similar among the CPP, HV, and EP. |
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http://brain.hastypastry.net/forums/showthread.php?t=39976
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| | FR Doc 05-15036 Pain Drug - TMC Reference - J. J. Keller & Associates, Inc. |
| | Pregabalin products will be prescription drugs used for the treatment of neuropathic pain. | | | Another commenter stated that, in their experience with pregabalin in clinical trials, pregabalin does not demonstrate any risk that would merit being considered a scheduled drug. | | | Data from clinical trials suggest that some of pregabalin's positive psychic effects are limited and do not continue with time or continued drug use. |
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http://jjkeller.com/referencematerials/072805PainDrug.html?...&pageseq=10000
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| | Those with neuropathic pain get a new treatment choice - Drug Topics |
| | One advantage of pregabalin is that—because it has a different mechanism of action from other drugs used to treat chronic pain—it can be used as an add-on drug to opioids and antidepressants. | | | Pregabalin is an alpha-2 delta ligand that acts on voltagegated calcium channels, explained Bill McCarberg, M.D., founder of the Chronic Pain Management Program for Kaiser Permanente in San Diego. | | | The pain of diabetic peripheral neuropathy (DPN) is often described as burning, tingling, sharp, stabbing, or pins and needles in the feet, legs, hands, or arms. |
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http://www.drugtopics.com/drugtopics/article/articleDetail.jsp?id=145836
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| | Scientific Abstracts |
| | Conclusions: Pregabalin is effective and safe for the treatment of pain at 450mg/day in patients with FMS in this study. | | | Pregabalin improves pain associated with fibromyalgia syndrome in a multicenter, randomized, placebo-controlled monotherapy trial. | | | To ascertain whether these drugs have effects on sensory neurons, we studied their actions on capsaicin-evoked release of the sensory neuropeptides, substance P and calcitonin gene-related peptide from rat spinal cord slices in vitro. |
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http://www.fmnetnews.com/pages/Issue65Abstr.htm
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| | Pregabalin news articles |
| | The experimental drug pregabalin, for example, can reduce the release of brain chemicals involved in the pain response. | | | Among these products already available locally are pregabalin (Lyrica) for neuropathic pain and as an adjunctive therapy for partial epileptic seizures... |
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http://www.mongabay.com/drugs/drugs/Pregabalin.html
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| | The Anxiety Community - Treatment - Medication: Pregabalin |
| | Pregabalin achieved significantly faster onset of sustained clinical improvement within the first week of treatment than placebo. | | | I am wondering if there is a relationship of pregabalin to 'date-rape' drugs like GHB or Rohypnol. | | | That explains why your doctor used a blue pad to write the Rx for pregabalin. |
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http://anxietyhelp.org/treatment/medication/pregabalin.html
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| | rheumatoid arthritis therapy |
| | According to a study published in the April 2005 issue of Arthritis & Rheumatism, Lyrica (pregabalin) significantly reduced the pain of fibromyalgia, improved sleep and fatigue, and improved other patient-reported conditions including bodily pain and vitality. |
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http://www.arthritis-online.com/arthritis/rheumatoid-arthritis-therapy
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| | Pfizer's Pregabalin Significantly Improves Pain Friendly Print |
| | NEW ORLEANS, October 26, 2002 -- Pfizer Inc's pregabalin was shown to provide improvement of pain in patients with fibromyalgia, a chronic and debilitating pain syndrome, according to data presented here today at the annual meeting of the American College of Rheumatology. | | | Developed by Pfizer, pregabalin has been studied in an extensive clinical program involving over 8,000 patients worldwide. | | | The company has completed pivotal studies to support the filing of a New Drug Application for pregabalin for the treatment of neuropathic pain and generalized anxiety disorder and as an add-on therapy for epilepsy. |
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http://www.fmaware.org/doctor/pfizerFP.htm
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| | AAN: Antiepileptic Pregabalin Appears Safe With Regard to Fertility Issues |
| | "Pregabalin will provide an additional treatment option that may allow people with epilepsy to better manage issues related to their reproductive health," said Martha Morrell, MD, Professor of Neurology, Columbia University, and director, Columbia Comprehensive Epilepsy Center, New York, United States. | | | Yerby said that some epilepsy drugs interfere with the effectiveness of oral contraceptives, and have led to unwanted pregnancies. | | | Many anti-epileptic medications are known to reduce the effectiveness of oral contraceptives, which can lead to unexpected pregnancies in patients with epilepsy. |
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http://www.pslgroup.com/dg/243f76.htm
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| | Pregabalin Improves Pain and Fatigue Symptoms in Patients With Fibromyalgia |
| | According to Dr. Crofford, within the next year, an application will be filed for approval for neuropathic pain and anxiety indications in the U.S. and in Europe, and "then there will have to be other studies with respect to fibromyalgia," she said. | | | Compared with those receiving placebo, patients treated with pregabalin 450 mg/day showed significant improvement in their endpoint mean pain score (-0.93; P | | | Pregabalin Improves Pain and Fatigue Symptoms in Patients With Fibromyalgia |
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http://www.immunesupport.com/library/bulletinarticle.cfm?ID=4279&PROD=PH174
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| | Peripheral Neuropathy Pain Go Away |
| | New Medications such as Pregabalin used as a treatment of peripheral neuropathic pain show promising results, but don't offer much hope for folks that would rather heal than just simply feel better. | | | Ultracet (acetaminophen), and Milnacipran show promising results at relieving pain, inflammation and swelling. |
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http://www.neprinolenzyme.com/peripheral-neuropathy.htm
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| | Family Pratice News: Pregabalin Promising for Epilepsy - Brief Article |
| | LOS ANGEL ES -- The investigational drug pregabalin improves control of epileptic seizures and has a reliable doseresponse profile, Dr. Eugene Ramsay reported in a poster session at the annual meeting of the American Epilepsy Society. | | | Doses of concurrent antiepileptics were not changed during baseline but could be reduced or discontinued during treatment with pregabalin depending on change in seizure frequency Patients received open treatment with pregabalin for up to 60 weeks; doses ranged from 100 mg/day to 600 mg/day. | | | The drug is in final clinical testing before being submitted for approval to the Food and Drug Administration. |
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http://www.findarticles.com/p/articles/mi_m0BJI/is_5_31/ai_72882010
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| | Pregabalin: New Add-On Treatment for Partial Onset Seizures : Epilepsy.com/Professionals |
| | In the fixed-dose group, patients were randomized to 1 of 3 effective dosages of pregabalin: 150, 300, or 600 mg/day or placebo. | | | In the flexible-dose group, patients received: 150-600 mg/day which was adjusted at regular intervals depending on treatment efficacy/tolerance; or placebo. | | | A total of 794 patients were enrolled in two 12-week, placebo-controlled, double-blind, randomized trials in which pregabalin was used as an add-on therapy administered in both fixed and flexible dose schedules. |
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http://professionals.epilepsy.com/page/ar_1101140933.html
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| | Pregabalin - Wikipedia, the free encyclopedia |
| | Pfizer applied for indication of pregabalin to treat generalized anxiety disorder; however, the FDA responded to this request with a non-favorable letter. | | | It should be noted that while gabapentin is not controlled in the US, pregabalin was put on Schedule V meaning that "abuse of the drug or other substance may lead to limited physical dependence or psychological dependence." | | | Pfizer's Lyrica Receives Positive Opinion From CHMP for the Treatment of Generalized Anxiety Disorder in Adults PR Newswire. |
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http://en.wikipedia.org/wiki/Pregabalin
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| | Pregabalin for Social Phobia |
| | This is a 12-week study, in which patients are randomly assigned to receive one of three doses of pregabalin (an investigational medication), or placebo. | | | Patients who successfully complete the 12 study weeks will be eligible to enter an "open-label" phase of the study, which allows patients to receive pregabalin, free of charge, until the medication is put on the market. | | | Patients 18 years or older, with a diagnosis of Generalized Social Phobia. |
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http://crnet.mgh.harvard.edu/clinical_trials/view_trial.asp?ct_id=365&...
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| | WebMD Health Search |
| | WebMD does not provide medical advice, diagnosis or treatment. | | | See more Web search results for "pregabalin" >> |
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http://webmd.com/search/search_results/?query=pregabalin&...
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| | HTS: Publications by James W. Jefferson, MD |
| | Feltner DE, Davidson JRT, Pollack MH, Stein MB, Futterer R, Jefferson JW, Lydiard RB, DuBoff E, Robinson P, Phelps M, Slomkowski M, Werth JL, Pande AC: A placebo-controlled, double-blind study of pregabalin treatment of social anxiety disorder: outcome and predictors of response. | | | Pande AC, Feltner DE, Jefferson JW, Davidson JRT, Pollack M, Stein MB, Lydiard RB, Futterer R, Robinson P, Slomkowski M, DuBoff E, Phelps M, Janney CA, Werth JL: Efficacy of the novel anxiolytic pregabalin in social anxiety disorder: a placebo-controlled, multicenter study. |
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http://www.healthtechsys.com/publications/princ_jefferson_pub.html
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