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| | Familial adenomatous polyposis - Wikipedia, the free encyclopedia |
 | | A genetic and clinical study of intestinal polyposis, a predisposing factor for carcinoma of the colon and rectum. | | | In constrast to the mouse models where >90% of tumors form in the small intestine, the Pirc rat forms tumors preferentially (>60%) in the large intestine, similar to the human clinical presentation. | | | Genetic screens, pharmacological testing, and other areas of research have allowed for discoveries in the mouse and rat to be applied to the study of human FAP. |
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http://en.wikipedia.org/wiki/Familial_adenomatous_polyposis
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| | ASCRS |
| | Restorative proctocolectomy or rectum-preserving surgery in patients with familial adenomatous polyposis: results of a prospective study. | | | Familial Adenomatous Polyposis (FAP) is a dominantly inherited growth disorder due to an inactivating mutation in the tumor suppressor gene APC. | | | The preoperative colonoscopy in FAP patients is important in helping determine the choice of operation, it's timing, and even the techniques of resection. |
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http://www.fascrs.org/displaycommon.cfm?an=1&subarticlenbr=114
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| | GENERATIONS - Familial Adenomatous Polyposis |
| | The term polyposis refers to a condition of often more than 100 mushroom-shaped growths called polyps on the surface lining of the large intestine. | | | Researchers have now discovered that FAP is a result of mutations in a gene called Adenomatous Polyposis Coli (APC) which is located on chromosome 5. | | | By developing a family history, each child, brother, and sister of someone with FAP can understand their need for genetic and colon examination to prevent bowel cancer. |
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http://www.generations.hk.com/background/Screening_FAP.php3
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| | APC-Associated Polyposis Conditions |
| | APC-associated polyposis condition in the affected family members and accurate understanding of genetic relationships in the family. | | | The penetrance of FAP in terms of colonic adenomatous polyposis and colon cancer is virtually 100% in untreated individuals. | | | BRR syndrome is a congenital disorder characterized by macrocephaly, intestinal polyposis, lipomas, and pigmented macules of the glans penis. |
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http://www.geneclinics.org/profiles/fap/details.html
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| | Familial polyposis |
| | Familial polyposis is an inherited condition which primarily affects the large intestine (colon and rectum). | | | FAP patients felt to be at lower risk for rectal polyps might be counseled to consider the less radical surgery. | | | This means that a person with FAP has a 50% chance of passing the condition down to each of their children. |
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http://www.lifesteps.com/gm/Atoz/ency/familial_polyposis.jsp
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| | MACGN - Familial Adenomatous Polyposis (FAP) |
| | It deals with polyposis and hereditary colon cancer and is free to all individuals with these conditions and their families. | | | FAP (Familial adenomatous polyposis) - An inherited disorder of the gastrointestinal tract in which there are 100 or more precancerous polyps. | | | Early diagnosis of FAP in many patients has led to early surgery, resulting in prevention or cure of colon cancer and increased life span. |
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http://www.macgn.org/cc_fap1.html
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| | Familial Adenomatous Polyposis - August 2001: 708716 |
| | AB - Familial adenomatous polyposis (FAP) is a common hereditary syndrome characterized by early development of colorectal cancer consequent to extensive adenomatous polyps of the colon. | | | MATERIAL AND METHODS: From November 1998 to November 2000, 32 individuals with putative familial/hereditary predisposition to colorectal cancer were investigated for adenomatous polyposis (attenuated or classical familial adenomatous polyposis coli, FAP) or for hereditary nonpolyposis colorectal cancer (HNPCC). | | | AB - Familial adenomatous polyposis is a dominantly inherited precancerous condition of the colorectum. |
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http://www.acor.org/cnet/708716.html
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| | Medical Dictionary: Familial adenomatous polyposis - WrongDiagnosis.com |
| | Unless this condition is treated, familial polyposis is almost certain to lead to colorectal cancer. | | | Familial adenomatous polyposis: Another name for Familial polyposis (or close medical condition association). | | | This means that Familial adenomatous polyposis, or a subtype of Familial adenomatous polyposis, affects less than 200,000 people in the US population. |
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http://www.wrongdiagnosis.com/medical/familial_adenomatous_polyposis_printer.htm
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| | Familial Adenomatous Polyposis (FAP) |
| | a nearly 100 percent risk of colorectal cancer in the absence of treatment for polyposis (colectomy, or surgery to remove the colon) | | | Familial adenomatous polyposis (FAP), also known as familial polyposis coli, adenomatous polyposis coli, or Gardner syndrome, is seen in approximately one in 8,000 individuals. | | | polyposis - the development of multiple benign (noncancerous) adenomatous polyps (>100) in the colon and rectum, which are described as having a "dense carpet-like appearance" on colonoscopy or sigmoidoscopy. |
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http://www.healthsystem.virginia.edu/uvahealth/hub_cancer/fap.cfm
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| | National Cancer Institute - Dictionary of Cancer Terms |
| | A narcotic opioid drug that is used in the treatment of pain. | | | A type of therapy in which the whole family talks with a professional counselor to solve family problems. | | | A condition marked by extreme tiredness and inability to function due lack of energy. |
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http://www.cancer.gov/dictionary/db_alpha.aspx?expand=f
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| | ThirdAge: Familial Adenomatous Polyposis |
| | Familial adenomatous polyposis (FAP) is a rare, inherited type of colorectal cancer. | | | FAP results in the development of hundreds of polyps inside the large intestine. | | | The primary risk factor for FAP is having family members with this condition. |
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http://www.thirdage.com/healthgate/files/22579.html
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| | Familial Adenomatous Polyposis - October 2001: 710716 |
| | We have investigated the underlying basis of variation in disease severity in the large intestine of familial adenomatous polyposis (FAP) patients. | | | Familial adenomatous polyposis is an autosomal dominant disease caused by a germ-line mutation of the adenomatous polyposis coli (APC) gene that causes colorectal cancer if prophylactic colectomy is not performed. | | | AB - Mutation of the adenomatous polyposis coli (APC) gene and the subsequent dysregulation of beta-catenin are well-documented abnormalities in familial adenomatous polyposis (FAP), as well as sporadic polyposis. |
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http://www.acor.org/cnet/710716.html
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| | eMedicine - Familial Adenomatous Polyposis : Article by John M Carethers, MD |
| | Because of the diffuse nature of the polyposis and the inevitability of colorectal cancer developing, surgical therapy ultimately is required. | | | Background: Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disorder characterized by the presence of hundreds to thousands of adenomatous polyps throughout the colon. | | | This is a photo of a colectomy specimen from a patient with familial adenomatous polyposis. |
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http://www.emedicine.com/MED/topic769.htm
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| | Treatment of Familial Adenomatous Polyposis at Mayo Clinic |
| | FAP results from a defect in the adenomatous polyposis coli (APC) gene and is autosomal dominant, meaning that only one parent must carry the mutated (abnormal) gene for a child to have a 50 percent chance of inheriting the disorder. | | | Familial adenomatous polyposis is a rare form of inherited colon cancer that causes hundreds to thousands of polyps to develop in the lining of the lower intestine (including the colon and rectum). | | | Familial adenomatous polyposis (FAP) is a genetic disorder that left undetected, almost always leads to colon cancer by the time a person reaches his or her 40s. |
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http://www.mayoclinic.org/familial-adenomatous-polyposis
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| | fap.html |
| | The predominant brain tumor in these 10 families was medulloblastoma (11 of 14 patients, or 79 percent), and the relative risk of cerebellar medulloblastoma in patients with familial adenomatous polyposis was 92 times that in the general population (95 percent confidence interval, 29 to 269; P < 0.001). | | | Germ-line mutations in the adenomatous polyposis coli (APC) gene characteristic of familial adenomatous polyposis were evaluated, as well as DNA replication errors and germline mutations in nucleotide mismatch-repair genes characteristic of hereditary nonpolyposis colorectal cancer. | | | Familial adenomatous polyposis is an inherited disease characterized by multiple colorectal tumors. |
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http://www.people.virginia.edu/~smp8n/malgentest/colon/fap/fap.html
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| | Medcyclopaedia - Familial adenomatous polyposis |
| | Two-thirds of the affected individuals have a familial history of polyposis. | | | Familial adenomatous polyposis (FAP) is part of the adenomatous polyposis syndromes including the Gardners syndrome and Turcots syndrome and an attenuated form of FAP. | | | Polyps in the antrum of the stomach in patients with FAP are of the adenomatous type. |
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http://www.medcyclopaedia.com/library/topics/volume_iv_1/f/FAMILIAL_ADENOMATOUS_POLYPOSIS.aspx
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| | GeneReviews: APC-Associated Polyposis Conditions |
| | Your browser does not support HTML frames so you must view APC-Associated Polyposis Conditions in a slightly less readable form. | | | GeneReviews are expert-authored, peer-reviewed, current disease descriptions that apply genetic testing to the diagnosis, management, and genetic counseling of patients and families with specific inherited conditions. |
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http://www.geneclinics.org/profiles/fap
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| | Familial adenomatous polyposis - References - Genetics Home Reference |
| | Jarvinen HJ, Paivi P. The complex genotype-phenotype relationship in familial adenomatous polyposis. | | | MYH mutations in patients with attenuated and classic polyposis and with young-onset colorectal cancer without polyps. | | | These sources were used to develop the Genetics Home Reference condition summary on familial adenomatous polyposis. |
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http://ghr.nlm.nih.gov/condition=familialadenomatouspolyposis/show/References
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| | Scientific Articles: Familial Adenomatous Polyposis |
| | Somatic APC and K-ras codon 12 mutations in periampullary adenomas and carcinomas from familial adenomatous polyposis patients. | | | Mutations of the adenomatous polyposis coli gene in familial polyposis coli patients and sporadic colorectal tumors. | | | Knowledge of the adenomatous polyposis coli gene and its clinical application. |
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http://www.csu.edu.au/learning/ncgr/gpi/odyssey/colon/fap_arts.html
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| | HEALTHMEDNET ILLNESS & DISEASE URL DIRECTORY |
| | Family Life Cycle - Parenting: Babies Through Adolescents | | | Family doctor - how to choose one see Choosing a primary care provider | | | Familial primary pulmonary hypertension see Primary pulmonary hypertension |
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http://www.healthmednet.com/Fah-Fhs.htm
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| | MedlinePlus: Colorectal Cancer |
| | Genetics Home Reference: Familial adenomatous polyposis (National Library of Medicine) | | | Screening a Lifesaver for Families at High Colon Cancer Risk (03/23/2006, American Cancer Society) |
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http://www.nlm.nih.gov/medlineplus/colorectalcancer.html
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| | APC - Adenomatosis polyposis coli - aka: FPC, DP2 - Cancer GeneticsWeb |
| | Inherited colorectal polyposis and cancer risk of the APC I1307K polymorphism. | | | Loss of normal allele of the APC gene in an adrenocortical carcinoma from a patient with familial adenomatous polyposis. | | | The relationship between frequencies of extracolonic manifestations and the position of APC germline mutation in patients with familial adenomatous polyposis. |
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http://www.cancerindex.org/geneweb/APC.htm
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| | Familial adenomatous polyposis |
| | diffuse adenomatous polyposis of the colon and rectum with extracolonic manifestations, duodenal adenomas, fundic gland polyps, congenital hypertrophy of the retinal pigment epithelium (CHRPE), osseous, subcutaneous and desmoid tumors
). | | | AAPC is clinically manifested as an isolated colonic polyposis, with polyps characterized by delayed occurrence (around 30 years) and reduced number (from few to a hundred), and rectal polyps may develop in exceptional cases. | | | Diagnosis of FAP is based on clinical examination of the classic manifestations of the disease (i.e. |
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http://www.orpha.net/data/patho/GB/uk-fap.html
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| | Familial polyposis coli (familial adenomatous polyposis or FAP) |
| | FAP arises because of a mutation in the adenomatous polyposis coli (APC) gene, on chromosome no 5, which carries the instructions for the manufacture of a protein involved in the regulation of cell growth. | | | Occasionally, problems occur with patients with 'attenuated FAP', who have fewer polyps. | | | The condition is characterised by the formation of polyps, also known as adenomas (because they are at a pre-cancerous stage, where they may or may not develop into cancerous cells). |
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http://www.netdoctor.co.uk/diseases/facts/fpc.htm
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