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| | Platelet - Wikipedia, the free encyclopedia |
 | | For example, aspirin irreversibly prevents platelets from working correctly and so normal hemostasis may not return until the aspirin is ceased and the affected platelets have been replaced by new ones, which may take over a week. | | | The body has a very limited reserve of platelets and so they can be rapidly depleted. | | | By drawing and returning blood repeatedly, a bag of high-quality platelets can be prepared in about 90 minutes. |
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http://en.wikipedia.org/wiki/Platelet
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| | AORN Journal: Intraoperative use of autologous platelet-rich and platelet-poor plasma for orthopedic surgery patients |
| | The developing body of medical literature documents use of autologous platelet gel and PPP in cardiothoracic surgery; cosmetic and plastic surgery; ear, nose, and throat surgery; general surgery; major vascular surgery; neurosurgery; obstetrics and gynecological surgery (ie, cesarean section, hysterectomy); ophthalmology; oral surgery; orthopedic surgery; urology; and wound healing. | | | (4) Autologous platelet gel was developed in the early 1990s as a by-product of PRP sequestration in cardiac surgery. | | | Use of autologous platelet concentrate to accelerate soft and hard tissue healing is strongly supported in medical literature. |
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http://www.findarticles.com/p/articles/mi_m0FSL/is_4_80/ai_n6260752
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| | eMedicine - Platelet Disorders : Article by Perumal Thiagarajan, MD |
| | It may be useful for determining global platelet function and for assessing the efficacy of antiplatelet therapy. | | | Careful examination of the peripheral smear is essential in a patient with thrombocytopenia. | | | Less commonly, other platelet antigens, such as HPA-5b, are responsible for neonatal alloimmune thrombocytopenia. |
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http://www.emedicine.com/med/topic987.htm
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| | Publications about Platelet Rich Plasma |
| | This study demonstrated autologous platelet gel as an effective hemostatic agent for sealing capillary beds during flap surgery, controlling bleeding and reducing the amount of post surgical bleeding. | | | The use of commercial glues and autologus platelet concentrates are revolutionizing many surgical fields. | | | The use of platelet-rich plasma (PRP) to accelerate the healing phase in Periodontal, Oral Surgical and Implant Surgical procedures is an effective and reliable method to achieve hard and soft tissue migration and adhesion, which has not been observed in other grafting techniques. |
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http://www.harvesttech.com/publications.htm
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| | CHRONO-LOG PLATELET AGGREGOMETER ABSTRACTS |
| | This study was designed to determine the benefit of aprotinin therapy in reducing bleeding during and after cardiopulmonary bypass in patients with preoperative platelet dysfunction. | | | During a median follow-up of 33 months, nine patients with and one patient without platelet hyperactivity respectively developed new thrombotic events before the addition of specific therapy. | | | A multi-laboratory evaluation of in vitro platelet assays: the tests for extent of shape change and response to hypotonic shock. |
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http://www.chronolog.com/ABSTRACT.HTM
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| | Platelet Aggregation |
| | A rapid, whole blood point-of-care device has been compared to platelet aggregation in monitoring platelet function during antiplatelet therapy. | | | GPIIb/IIIa mediates platelet aggregation using fibrinogen to link platelets to each other. | | | An on-line literature search for each medication is often informative. |
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http://www.mgh.harvard.edu/labmed/lab/coag/handbook/co003900.htm
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| | Platelet Disorders |
| | Jilma B. Platelet function analyzer (PFA-100): a tool to quantify congenital or acquired platelet dysfunction. | | | PFA-100 system: a new method for assessment of platelet dysfunction. | | | Platelet destruction results from a variety of immune conditions including the following: |
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http://www.clevelandclinicmeded.com/diseasemanagement/hematology/platelet/platelet.htm
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| | Platelet Immunology |
| | Another approach is to obtain an eluate from platelets, and then react the eluate against platelets: only platelet autoantibodies react under these circumstances, and this results in sensitivity and specificity for AITP similar to that of the direct MAIPA. | | | The laboratory also needs to review the peripheral blood film to rule out disorders such as pseudothrombocytopenia, platelet satellitism, May-Hegglin anomaly, Sebastian syndrome, etc. A commercial GP-specific assay was assessed by Dr. Kiefer but was found to react poorly with many platelet autoantibodies (this assay is adequate for detecting alloantibodies). | | | Current research activities aimed at elucidating a biological role for SNPs in platelet physiology were summarized. |
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http://www.med.unc.edu/isth/SSC/03sscminutes/03plateletimmun.html
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| | Adverse Reactions to Platelet Transfusion, Risks and Probable Causes |
| | Siren A. Feuerstein G. Effects of PAF and BN52021 on cardiac function and regional blood flow in conscious rats. | | | The transient hypotension was thought to result in a dilation of peripheral resistance vessels. | | | Red cells undergo physical changes in storage such as shape changes and biochemical changes such as a decline in 2,3 - DPG levels. |
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http://www.pall.com/34445_6494.asp
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| | July 2000 - Platelet Closure Times |
| | It may also be useful to monitor the response of therapeutics, such as DDAVP infusions, renal dialysis, platelet and antiplatelet drug therapy. | | | As a consequence many clinicians no longer use BT. | | | “PFA-100 System: A new method for assessment of platelet dysfunction |
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http://www.itxm.org/TMU2000/tmu7-2000.htm
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| | THE MERCK MANUAL, Sec. 11, Ch. 133, Platelet Disorders |
| | Platelets may become dysfunctional, prolonging the bleeding time, as blood circulates through a pump oxygenator during cardiopulmonary bypass surgery. | | | During bypass surgery, giving aprotinin (a protease inhibitor that neutralizes plasmin activity) reportedly prevents prolongation of the bleeding time and reduces the need for blood replacement. | | | Many other drugs may also induce platelet dysfunction. |
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http://www.merck.com/pubs/mmanual/section11/chapter133/133c.htm
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| | Qualitative Platelet Disorders |
| | You should speak to your physician or make an appointment to be seen if you have questions or concerns about this information or your medical condition. | | | The platelets therefore do not aggregate or stick to each other properly. | | | A quantitative platelet disorder is a condition in which there are not enough platelets. |
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http://www.med.umich.edu/1libr/aha/umqpd.htm
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| | Platelet Therapy - Platelet Concentration |
| | This coagulum or "platelet gel" has an extremely wide-range of clinical healing uses from dental surgery to orthopedics and plastic surgery. | | | We believe that as awareness of autologous platelet gel grows, its use in a variety of clinical healing applications will also increase. | | | Autologous platelet gel should ONLY be prepared by or under the direction of a certified and (or) licensed clinical perfusionist. |
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http://www.perfusion.com/perfusion/plateletgel.asp
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| | Platelet Function Testing in Cardiovascular Diseases -- Michelson 110 (19): e489 -- Circulation |
| | Circulating monocyte–platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin: studies in baboons, human coronary intervention, and human acute myocardial infarction. | | | Sex Differences in Platelet Reactivity and Response to Low-Dose Aspirin Therapy | | | Platelet Response to Low-Dose Enteric-Coated Aspirin in Patients With Stable Cardiovascular Disease |
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http://circ.ahajournals.org/cgi/content/full/110/19/e489
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| | Platelet Research Laboratory |
| | The Platelet Research Laboratory performs additional assays, equally important for the analysis of the mechanisms involved in alterations of hemostasis and the pathogenesis of thrombosis: | | | Images illustrating some aspects of the mentioned assays and techniques. | | | Electrophoretic gel to detect phosphotyrosin proteins after platelet adhesion onto collagen. |
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http://www.platelet-research.org/1/techniques_addi.htm
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| | Inherited Platelet Disorders -- Handin 2005 (1): 396 -- Hematology |
| | Human blood platelets showing no response to collagen fail to express surface glycoprotein Ia. Nature. | | | To underscore the importance of this pathway, there is a rare | | | Inherited Platelet Disorders -- Handin 2005 (1): 396 -- Hematology |
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http://www.asheducationbook.org/cgi/content/full/2005/1/396
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| | Guidelines for the Management of Platelet Disorders |
| | While platelet transfusions may be used, they are not very effective. | | | Platelet transfusions are not usually effective in immune-mediated thrombocytopenias, such as idiopathic thrombocytopenia purpura (ITP), although there may be some benefit in life-threatening situations. | | | Immune-mediated platelet consumption: acute and chronic autoimmune thrombocytopenic purpura, drug-induced immune thrombocytopenia, neonatal alloimmune thrombocytopenia, post-transfusion purpura |
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http://peir.path.uab.edu/coag/printer_223.shtml
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| | Acquired platelet disorders |
| | However, further studies need to be performed in this area. | | | However, it should be recognised that platelets are not functioning normally in these situations and drugs that may exacerbate this should be avoided in these patients. | | | This correlated to the immunoglobulin G fraction of the patients' sera. |
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http://www.diaglab.vet.cornell.edu/clinpath/modules/coags/acqplfun.htm
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| | Congenital platelet function defects |
| | You should promptly seek professional medical care if you have any concern about your health, and you should always consult your physician before starting a fitness regimen. | | | Congenital platelet function defects are disorders of platelet function, the blood cells essential for the coagulation of the blood, that is present at birth. | | | Bernard-Soulier syndrome is a congenital disorder where the platelets lack receptors to adhere to the walls of the blood vessels. |
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http://drdean.healthcentral.com/ency/408/000582.html
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| | ICU - Platelet dysfunction |
| | Such a mechanism would be consistent with the global effects of these drugs on platelet functions, and the observed relationship between the lipid solubility of various drugs and their antiplatelet effects. | | | Acquired platelet dysfunction has been described as being 'second only to thrombocytopenia as the major cause of clinical bleeding disorders.' Additionally, several acquired qualitative platelet disorders have been associated with thrombotic tendencies. | | | It is known that the drug shortens the bleeding time of patients with mild hemophilia or von Willebrand's disease (and may precipitate platelet aggregation in type IIb von Willebrand's disease), as well as patients with uremia. |
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http://www.anzics.com.au/teaching/phvc/platelet.html
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| | Platelet Count: The Test |
| | Bleeding disorders or other bone marrow diseases, such as leukemia, require the determination of the number of platelets present and/or their ability to function correctly. | | | Certain drugs, such as heparin, quinidine, sulfa drugs, oral anti-diabetic drugs, and even alcohol, may cause decreased platelet counts. | | | Increased platelet counts (thrombocytosis) may be seen in individuals who show no significant medical problems, while others may have a more significant blood problem called myeloproliferative disorder (abnormal growth of blood cell elements). |
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http://www.labtestsonline.org/understanding/analytes/platelet/test.html
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| | MedlinePlus Medical Encyclopedia: Platelet count |
| | A platelet count may be performed under many conditions and to assess many diseases. | | | Veins and arteries vary in size from one patient to another and from one side of the body to the other. | | | If the number of platelets is below normal (thrombocytopenia), this may be associated with: |
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http://www.nlm.nih.gov/medlineplus/ency/article/003647.htm
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| | blood platelet - Hutchinson encyclopedia article about blood platelet |
| | Tiny disc-shaped structure found in the blood, which helps it to clot. | | | This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. | | | They play a vital role in blood clotting as they release blood clotting factors at the site of a cut. |
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http://encyclopedia.farlex.com/blood+platelet
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| | Platelet definition - Medical Dictionary definitions of popular medical terms |
| | Platelet definition - Medical Dictionary definitions of popular medical terms | | | Heart Attack - Overview on heart attack (myocardial infarction) and heart attack symptoms including signs of a heart attack, includes causes, risk factors, prevention, and treatment. | | | Although platelets are often classed as blood cells, they are actually fragments of large bone marrow cells called megakaryocytes. |
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http://www.medterms.com/script/main/art.asp?articlekey=4941
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| | platelet - OneLook Dictionary Search |
| | This is a OneLook Word of the Day, which means it might be in the news. | | | Words similar to platelet: thrombocyte, blood platelet, more... | | | platelet : Dictionary of Cancer Terms [home, info] |
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http://www.onelook.com/?w=platelet&loc=wotd
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| | Platelet Donations |
| | Most of the platelets in the body are stored in the bone marrow, liver, and spleen. When the number of circulating platelets is decreased, the body responds by sending platelets from storage areas into the blood circulation. There are a large amount of platelets in the circulating blood as well. | | | Patients receiving chemotherapy and/or radiation treatment and those who are having a Bone Marrow Transplant, have especially low platelet counts and can bleed very easily. We need people to give platelets to maintain an adequate supply for these patients. | | | Since there are no red blood cells in a platelet product, we are not limited to using the same donor blood types as with red cells. |
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http://www.childrenshospitalla.org/body.cfm?id=451
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| | platelet |
| | a small platelike body, esp. a blood platelet. |
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http://www.infoplease.com/dictionary/platelet
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