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Topic: Platelet-activating factor

Ads by Google Related Topics platelet derived growth factor Platelet activating factor      Role of Platelet-Activating Factor in Cardiovascular Pathophysiology -- Montrucchio et al. 80 (4): 1669 -- ... When the effects of PAF infusion were studied in the anesthetized dogs, a triphasic response was observed (35, 208). (279), and by experiments of platelet depletion (161). The role of PAF as mediator of direct interaction between platelets and endothelium is controversial. http://physrev.physiology.org/cgi/content/full/80/4/1669   (8858 words)      The Platelet-Activating Factor Receptor Activates the Extracellular Signal-Regulated Kinase Mitogen-Activated Protein ... Recent studies have suggested that the PAF system plays an important role in keratinocyte function and stress responses. In the skin, there is evidence that PAF-mediated pathways are involved in cutaneous inflammation and keratinocyte stress responses. The ability of the PAF-R to transactivate the EGF-R was significant as this pathway was found to be responsible for PAF-R-mediated http://jpet.aspetjournals.org/cgi/content/full/300/3/1026   (5894 words)      Effects of a Potent Platelet-activating Factor Antagonist, SR27417A, on Allergen-induced Asthmatic Responses -- EVANS ... Despite in vitro and in vivo data in humans that would support a role for PAF in asthma, previous human studies with PAF antagonists, and MK287 (21), suggest that PAF is not an important mediator The lack of effect of SR27417A on baseline lung function and airway responsiveness warrants further discussion. http://ajrccm.atsjournals.org/cgi/content/full/156/1/11   (2751 words)      The role of platelet activating factor in a neonatal piglet model of necrotising enterocolitis -- Ewer et al. 53 (2): ... Caplan MS, Kelly A, Hseuh W. Endotoxin and hypoxia-induced intestinal necrosis in rats: the role of platelet-activating factor. Feeding practices for infants weighing less than 1500 G at birth and the pathogenesis of necrotizing enterocolitis. Intestinal blood flow and oxygen consumption: responses to haemorrhage in the developing piglet. http://gut.bmjjournals.com/cgi/content/full/53/2/207   (3982 words)      Platelet-Activating Factor Induces Nitric Oxide Synthesis in Trypanosoma cruzi-Infected Macrophages and Mediates ... In the present study, we have investigated whether PAF plays a role in mediating resistance against T. a possible role for PAF in acute myocarditis in T. in response to PAF were markedly lower than those observed when http://iai.asm.org/cgi/content/full/67/6/2810   (2788 words)      Platelet-activating Factor-mediated NF-{kappa}B Dependency of a Late Anaphylactic Reaction -- Choi et al. 198 (1): 145 ... Interleukin-1-induced leukocyte extravasation across rat mesenteric microvessels is mediated by platelet-activating factor. PAF synthesis is not fully understood, it seems likely that Results for all panels are expressed as the mean ± SEM of three to seven separate experiments (n = 4 for each time point). http://www.jem.org/cgi/content/full/198/1/145   (3226 words)      Localization of the Platelet-Activating Factor Receptor to Rat Pancreatic Microvascular Endothelial Cells -- Flickinger ... Kingsnorth AW, Galloway SW, Formela LJ: Randomized, double-blind phase II trial of Lexipafant, a platelet-activating factor antagonist, in human acute pancreatitis. Intracellular calcium measurements in rat PIEC following exposure to PAF (100 nmol/L). 2-lyso-PAF necessary for PAF synthesis via the remodeling pathway. http://ajp.amjpathol.org/cgi/content/full/154/5/1353   (3089 words)      Increased Platelet-Activating Factor Receptor Gene Expression by Corneal Epithelial Wound Healing -- Ma and Bazan 41 ... This experiment was performed three times with similar results each time. feedback mechanism to maintain a PAF response in epithelial We are aware of only one in vivo study showing that http://www.iovs.org/cgi/content/full/41/7/1696   (4673 words)      Characterization of Platelet-activating Factor Acetylhydrolase in Human Bronchoalveolar Lavage -- TRIGGIANI et al. 156 ... may be responsible for a slower inactivation of PAF and, ultimately, factor (PAF) acetylhydrolase activity in human skin after antigen BAL-AH activity is influenced by oxygen radicals, we measured http://ajrccm.atsjournals.org/cgi/content/full/156/1/94   (4110 words)      Neurological Research: Production of platelet-activating factor by neuronal cells in the rat brain with cold injury Immunofluorescent staining was used to detect PAF in the rat brain with cold-induced local brain injury. Keywords: Brain injury; cold injury; platelet-activating factor; rat Cerebrovascular and cerebrometabolic effects of intracarotid infused platelet-activating factor in rats. http://www.findarticles.com/p/articles/mi_qa3909/is_200109/ai_n8983477   (1247 words)      Association of a G994->T Missense Mutation in the Plasma Platelet-Activating Factor Acetylhydrolase Gene With Genetic ... PAF may also act as a secondary mediator of the effects of PAF also acts as a secondary mediator of the effects are structurally similar to PAF and mimic its biological actions. http://circ.ahajournals.org/cgi/content/full/98/18/1881   (3157 words)      Platelet-Activating Factor Induction of Activator Protein-1 Signaling in Bronchial Epithelial Cells -- Levan et al. 53 ... The results of our study demonstrate that PAF receptors are expressed on the surface of primary human bronchial epithelial That PAF is capable of induction of the AP-1 signaling pathway in bronchial epithelial cells may have several implications. factor exerts mitogenic activity and stimulates expression of http://molpharm.aspetjournals.org/cgi/content/full/53/1/135   (3734 words)      BN 52021: A Platelet Activating Factor Antagonist for Preventing Post-Transplant Renal Failure: A Double-Blind, ... Protective effect of the PAF antagonist BN 52021 in an experimental renal warm ischemia model. release of platelet activating factor mimic the responses observed BN 52021: A Platelet Activating Factor Antagonist for Preventing Post-Transplant Renal Failure: A Double-Blind, Randomized Study. http://www.annals.org/cgi/content/full/121/5/345   (1349 words)      Corticotrophin-releasing hormone and platelet-activating factor induce transcription of the type-2 cyclo-oxygenase gene ... factor (PAF) are considered to be involved in the physiological through which CRH and PAF exert their latter effect. Effects of platelet-activating factor on cytokine production by human uterine cervical fibroblasts http://molehr.oxfordjournals.org/cgi/content/abstract/5/5/476   (324 words)      Platelet activating factor acetylhydrolase Please send any questions or comments about the Human Protein Reference Database to help You are at: Home » Proteins » Platelet activating factor acetylhydrolase http://www.hprd.org/protein/03407   (35 words)

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