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Topic: Photoreceptor



  
 WHAT ARE THE MECHANISMS OF PHOTORECEPTOR ADAPTATION?
The time scale for dissociation, tens of seconds, corresponds to the period during continuous bright illumination of photoreceptors when an increase in the response recovery rate is being observed (Coles and Yamane, 1975; Cervetto et al., 1984; McCarthy and Owen, personal communication).
It is clear that these structures determine the basic parameters that define subsequent stages of visual information processing in the retina (cf.
McNaughton, P.A. (1990) Light response of vertebrate photoreceptors.
http://www.bbsonline.org/documents/a/00/00/04/35/bbs00000435-00/bbs.neur3.bownds.html   (11479 words)

  
 Molecular ophthalmology: an update on animal models for retinal degenerations and dystrophies -- HAFEZI et al. 84 (8): ...
photoreceptor apoptosis using a multitude of different approaches.
of the signalling pathway from light to photoreceptor death by
c-fos controls the "private pathway" of light-induced apoptosis of retinal photoreceptors.
http://www.bjophthalmol.com/cgi/content/full/84/8/922   (4444 words)

  
 Photoreceptor - Wikipedia, the free encyclopedia
In humans, the visual system uses thousands of such photoreceptors to view, percieve, and analyze the visual world.
Below is the absorption spectrum for the rod and three cones found in the human retina:
Commonly misunderstood is the function of the photoreceptors.
http://en.wikipedia.org/wiki/Photoreceptor   (885 words)

  
 The Role of Subunit Assembly in Peripherin-2 Targeting to Rod Photoreceptor Disk Membranes and Retinitis Pigmentosa -- ...
appearance and degeneration of central and peripheral photoreceptors
inner segments and cilium further contributes to photoreceptor
ROS indicated that peripherin-2-GFP expression did not affect
http://www.molbiolcell.org/cgi/content/full/14/8/3400   (6617 words)

  
 Action Spectrum for Melatonin Regulation in Humans: Evidence for a Novel Circadian Photoreceptor -- Brainard et al. 21 ...
Action Spectrum for Melatonin Regulation in Humans: Evidence for a Novel Circadian Photoreceptor -- Brainard et al.
http://www.jneurosci.org/cgi/reprint/21/16/6405   (17 words)

  
 The Phosphatidylinositol Transfer Protein Domain of Drosophila Retinal Degeneration B Protein Is Essential for ...
of the light response and dark recovery of the photoreceptor cell;
phototransduction light response and dark recovery of the photoreceptor
does not simply function to transfer phospholipids in the photoreceptor
http://www.jcb.org/cgi/content/full/139/2/351   (7556 words)

  
 The Serine-Rich N-Terminal Domain of Oat Phytochrome A Helps Regulate Light Responses and Subnuclear Localization of ...
6-12 phyA behaved as a hyperactive photoreceptor in the VLFR for tobacco (Fig.
phyA, indicating that both photoreceptors repress the response.
the phyA photoreceptor, most of it is rapidly lost upon transfer
http://www.plantphysiol.org/cgi/content/full/129/3/1127   (6020 words)

  
 Formate-Induced Inhibition of Photoreceptor Function in Methanol Intoxication -- Seme et al. 289 (1): 361 -- Journal of ...
focused upon the inner segments of the photoreceptors because
swelling of photoreceptor inner segments, and morphologic changes
The Na /Ca exchanger in rods has been reported to be five times slower than
http://www.jpet.org/cgi/content/full/289/1/361   (6659 words)

  
 vitamin - Columbia Encyclopedia® article about vitamin
One form, retinal, is a component of visual purple, a photoreceptor pigment in the retina of the eye (see vision vision, physiological sense of sight by which the form, color, size, movements, and distance of objects are perceived.
The human eye functions somewhat like a camera; that is, it receives and focuses light upon a photosensitive receiver, the retina.
Vitamin A is essential to skeletal growth, normal reproductive function, and the health of the skin and mucous membranes.
http://columbia.thefreedictionary.com/vitamin   (3868 words)

  
 Nat' Academies Press, Night Vision: Current Research and Future Directions, Symposium Proceedings (1987)
Some can have 20/20 vision but are legally blind due to the profound loss of their peripheral visual field with consequent "tunnel vision." Most of these disorders occur as a consequence of malfunction and loss of rod and cone photoreceptors.
One must keep in mind, however, that high gain alone does not guarantee optimum detection of a dim light.
Sensitive tests of retinal function have made it possible to diagnose these conditions in their earliest stages, sometimes many years before the patient is symptomatic or changes can be seen on routine ocular examination.
http://www.nap.edu/books/POD259/html/23.html   (6933 words)

  
 Rescue from Photoreceptor Degeneration in the rd Mouse by Human Immunodeficiency Virus Vector-Mediated Gene Transfer -- ...
This is the first study to establish the therapeutic ability of
Present address: Department of Ophthalmology and Visual Sciences, Graduate School of Medicine, Kyoto University, Sakyo-ku,
of photoreceptor cells, suggesting that somatic gene therapy to
http://jvi.asm.org/cgi/content/full/73/9/7812   (2851 words)

  
 ss-Dystroglycan Localization in the Photoreceptor and Muller cells in the Rat Retina Revealed by Immunoelectron ...
suggest that ß-DG may interact with dystrophin in photoreceptor
Recent studies have suggested that dystroglycan might function
Department of Anatomy, Yamanashi Medical University, Yamanashi, Japan
http://www.jhc.org/cgi/content/full/46/2/185   (3033 words)

  
 Report of the Angelo Coast Range Reserve NSF Planning Workshop
Our lab is investigating the roles of cytoskeletal motors in motile events critical to the morphogenesis and survival of vertebrate retinal photoreceptors, and thus to human vision.
Photoreceptor localization of the KIF3A and KIF3B subunits of the heterotrimeric microtubule motor kinesin II in vertebrate retina.
http://cbc.berkeley.edu/wkshpreport/index.html   (9599 words)

  
 The chicken RaxL gene plays a role in the initiation of photoreceptor differentiation -- Chen and Cepko 129 (23): 5363 ...
A Role of ath5 in Inducing neuroD and the Photoreceptor Pathway
Ciliary Photoreceptors with a Vertebrate-Type Opsin in an Invertebrate Brain
chicken, Rax and RaxL, and on the function of RaxL in photoreceptor development.
http://dev.biologists.org/cgi/content/abstract/129/23/5363   (532 words)

  
 IBEA Researchers Publish Results From Environmental Shotgun Sequencing of Sargasso Sea in Science; Discover 1,800 New ...
Only a few dozen photoreceptors have been characterized in microorganisms to date and less than 200 photoreceptors have been discovered from all species, including human where they are responsible for our vision.
Better understanding of these photoreceptor genes could be very important to IBEA researchers as they explore the mechanisms of photosynthesis as a means to efficiently and economically produce hydrogen as a fuel source.
One interpretation of this finding is that at least 50% of the new species discovered use some type of photobiology and could explain the diversity of species in such a low nutrient environment.
http://www.forrelease.com/D20040304/phth021.P2.03042004153112.21138.html   (1192 words)

  
 Light-induced, reversible modifications of the putative photoreceptor protein of Dictyostelium discoideum amoebae
The mechanism for the light perception is supposed to be based on a lens effect [5, 10].
The assumption that slugs and amoebae use different photoreceptor systems for their phototaxis is not only supported by the two different action spectra but also by the fact that amoebae cannot use the lens effect because of their small size and highly variable form.
In the last few decades the eukaryotic cellular slime mold, Dictyostelium discoideum, has developed into a model system in which many different basic cellular processes can be studied at a molecular level.
http://www.photobiology.com/v1/lebert1/index.htm   (2629 words)

  
 Photoreceptors, circadian, dynamin, multivesicular bodies, MVB, rhabdomeres, rhodopsin, lysosomes, autophagy, turnover, ...
Multivesicular bodies (MVB's) were clearly seen to be merging with primary lysosomes to form secondary lysosomes for membrane breakdown.
Rhodopsin mutants as well as transduction mutants such as norpA (no receptor potential) were used to determine the involvement of light initiated visual excitation in photoreceptor maintenance.
An electron micrograph from a photoreceptor in the Drosophila compound eye showing a multivesicular body (MVB) surrounded by primary lysosomes, components of the autophagy process.
http://starklab.slu.edu/turnover.htm   (516 words)

  
 Burnside Lab, Univeristy of California Berkeley
Our lab is interested in studying the photoreceptor actin cytoskeleton and understanding its contribution to the morphogenesis, maintenance, and survival of vertebrate rods and cones, and hence to vision.
Currently, we have focused our research on two proteins associated with the photoreceptor actin cytoskeleton, myosin 3A and fascin 2.
Contact Us Cone Photoreceptor of Striped Bass stained for myosin 3A (green) and Phalloidin (red).
http://mcb.berkeley.edu/labs/burnside   (64 words)

  
 CiteULike: Activation, deactivation, and adaptation in vertebrate photoreceptor cells.
A quiet revolution in the study of the mechanism has occurred during the past decade with the advent of gene-targeting techniques.
CiteULike will not help you view an online article which you aren't authorized to view.
Visual transduction captures widespread interest because its G-protein signaling motif recurs throughout nature yet is uniquely accessible for study in the photoreceptor cells.
http://www.citeulike.org/user/morven/article/343404   (180 words)

  
 The Human is a Digital Mechanism.
It would seem that the human nervous system is quite slow, but nature has some tricks up its sleeve also.
A separate nerve axon carries the signal from each photoreceptor into the brain.
Since we know that sight images require about 50 milliseconds, then the signals from each photoreceptor must "circulate" in the brain about 50 times before serving its complete function.
http://www.onelife.com/evolve/digman.html   (3544 words)

  
 Effect of preoperative detection of photoreceptor displacement on postoperative foveal findings in eyes with idiopathic ...
Department of Ophthalmology, Asahikawa Medical College, Asahikawa, Japan
in patients in whom photoreceptor displacement (82%, 9/11) was
patients in whom photoreceptor displacement was detected preoperatively
http://bjo.bmjjournals.com/cgi/content/full/87/4/506   (620 words)

  
 Tramtrack69 Is Positively and Autonomously Required for Drosophila Photoreceptor Development -- Lai and Li 152 (1): 299 ...
Ttk69 becomes a positive regulator critical for photoreceptor
, 1996  Genetic interactions of pokkuri with seven in absentia, tramtrack and downstream components of the sevenless pathway in R7 photoreceptor induction in Drosophila melanogaster.
a positive function of ttk69 in photoreceptor cell development.
http://www.genetics.org/cgi/content/full/152/1/299   (3925 words)

  
 Interactions between a blue-green reversible photoreceptor and a separate UV-B receptor in stomatal guard cells -- ...
Green light and UV-A drive the physiologically active
photoreceptor, how does one explain the lack of GL antagonism
and PHOT1 and PHOT2, which encode phototropins, the BL photoreceptors
http://www.amjbot.org/cgi/content/full/90/11/1560   (3826 words)

  
 Differential Roles of CD36 and {alpha}v{beta}5 Integrin in Photoreceptor Phagocytosis by the Retinal Pigment Epithelium ...
Differential Roles of CD36 and {alpha}v{beta}5 Integrin in Photoreceptor Phagocytosis by the Retinal Pigment Epithelium -- Finnemann and Silverstein 194 (9): 1289 -- The Journal of Experimental Medicine
The Journal of Experimental Medicine, Volume 194, Number 9, November 5, 2001 1289-1298
Address correspondence to Silvia C. Finnemann, Margaret M. Dyson Vision Research Institute, Box 233 Weill Medical College of Cornell University, 1300 York Ave., New York, NY 10021.
http://www.jem.org/cgi/content/full/194/9/1289   (6498 words)

  
 Molecular Forms of Human Rhodopsin Kinase (GRK1) -- Zhao et al. 273 (9): 5124 -- Journal of Biological Chemistry
Low Expression of {alpha}A-Crystallins and Rhodopsin Kinase of Photoreceptors in Retinal Dystrophy Rat
it appears that both rod and cone photoreceptors express GRK1.
Based on results of molecular cloning and immunolocalization,
http://www.jbc.org/cgi/content/abstract/273/9/5124   (907 words)

  
 Photoreceptor cell - Wikipedia, the free encyclopedia
The function of the photoreceptor cell is to convert the light energy into a form of energy more readily usable or functional to the organism: this conversion is called signal transduction.
Photoreceptor cells are found in the retina of the eye and are responsible for transducing, or converting, light into nerve signals that can be ultimately transmitted to the brain via the optic nerve.
The pathway for photoreceptor cells follows these basic steps:
http://www.wikipedia.org/wiki/Photoreceptor_cell   (418 words)

  
 The genetics of inherited macular dystrophies -- Michaelides et al. 40 (9): 641 -- Journal of Medical Genetics
suggest that successful gene therapy in patients with photoreceptor
Restoration of photoreceptor ultrastructure and function in retinal degeneration slow mice by gene therapy.
to the RPE, with consequent secondary photoreceptor degeneration.
http://jmg.bmjjournals.com/cgi/content/full/40/9/641   (6720 words)

  
 Newswise
Light regulates several physiological processes in fungi, including their ability to produce spores and the synchronization of their internal biological clocks, but their photoreceptors -- receptors that are sensitive to light and are essential for most ongoing processes -- were not known until this breakthrough discovery made by UT Southwestern researchers.
After 40 years of searching for the photoreceptor that controls multiple vital processes in fungi, researchers at UT Southwestern Medical Center at Dallas have discovered the protein that triggers this phenomenon.
July 4, 2002 -- After 40 years of searching for the photoreceptor that controls multiple vital processes in fungi, researchers at UT Southwestern Medical Center at Dallas have discovered the protein that triggers this phenomenon.
http://www.newswise.com/articles/2002/7/PHOTORCP.SWM.html   (558 words)

  
 Calcitic microlenses as part of the photoreceptor system in brittlestars : Nature
Calcitic microlenses as part of the photoreceptor system in brittlestars : Nature
Calcitic microlenses as part of the photoreceptor system in brittlestars
These results provide experimental evidence that the microlenses are optical elements that guide and focus the light inside the tissue.
http://www.nature.com/doifinder/10.1038/35090573   (282 words)

  
 01-080 (New Photoreceptor)
This signal then moves along a pathway between the cells and the brain.
Brown researchers find new photoreceptor and visual system in the eye
This change triggers a cascade of biochemical reactions and an electrical response in the photoreceptor.
http://www.brown.edu/Administration/News_Bureau/2001-02/01-080.html   (929 words)

  
 The cone dysfunction syndromes -- Michaelides et al. 88 (2): 291 -- British Journal of Ophthalmology
Mutations in the cone photoreceptor G-protein alpha-subunit gene GNAT2 in patients with achromatopsia.
life and patients often develop rod photoreceptor dysfunction
thereby lowering the concentration of cGMP in the photoreceptor
http://www.bjophthalmol.com/cgi/content/full/88/2/291   (4543 words)

  
 Photoreceptor - definition of Photoreceptor in Encyclopedia
Photoreceptor can also refer to the cells found in ommatidia and retina that contain these photosensitive pigments (see photoreceptor cell).
Photoreceptors are light-sensitive proteins involved in the function of photoreceptor cells.
Embed a dictionary search in your own web page
http://encyclopedia.laborlawtalk.com/Photoreceptor   (82 words)

  
 Photoreceptor Proteins: Smart Materials for the Electronics of the Next Millennium
During the past 30 years biochemists have analysed the structure and functioning of such proteins in detail.
Developing technical applications making use of the opto-electrical mechanisms of these photoreceptor proteins could meet some of the increasing demands from state of the art information technology.
A number of other photoreceptor proteins could also have technical applications.
http://www.jrc.es/pages/iptsreport/vol29/english/BIO1E296.htm   (2641 words)

  
 Oxidative Stress Plays an Important Role in the Pathogenesis of Drug-Induced Retinopathy -- Toler 229 (7): 607 -- ...
Reactive oxygen species as mediators of photoreceptor apoptosis in vitro.
of iodoacetate, morphologic changes in the photoreceptor cells
Chang CW, Chu G, Hinz BJ, Greve MD. Current use of dietary supplementation in patients with age-related macular degeneration.
http://www.ebmonline.org/cgi/content/full/229/7/607   (3986 words)

  
 Ionic mechanisms of phototransduction in photoreceptor cells from the epistellar body of the octopus eledone cirrhosa ...
Ionic mechanisms of phototransduction in photoreceptor cells from the epistellar body of the octopus eledone cirrhosa
Ionic mechanisms of phototransduction in photoreceptor cells from the epistellar body of the octopus eledone cirrhosa -- Cobb and Williamson 202 (8): 977 -- Journal of Experimental Biology
Intracellular recordings were made from extraocular photoreceptor cells
http://jeb.biologists.org/cgi/content/abstract/202/8/977   (362 words)

  
 Botany online: Plant Responses - Light - Phototaxis
This seemed to suggest that the stigma is a photoreceptor, though two observations were contrary.
Its action spectrum does not directly lead to the absorption spectrum of the photoreceptor, though, since part of the light is selectively absorbed by the stigma - it is also spoken of
In many other cases has the light to pass plastids with all their different pigments.
http://www.biologie.uni-hamburg.de/b-online/e30/30a.htm   (432 words)

  
 IngentaConnect Photoreceptor subtype specification: from flies to humans
IngentaConnect Photoreceptor subtype specification: from flies to humans
http://www.ingentaconnect.com/content/ap/sr/2001/00000012/00000006/art00275   (8 words)

  
 HHMI News: Researchers Identify Unique Circadian Rhythm Photoreceptor
If there were circadian photoreceptors other than dCRY, then constant light should have produced such arrhythmia.
Experiments by Rosbash and his colleagues now indicate that the fly cryptochrome dCRY is perhaps the only photoreceptor molecule through which light regulates the fly's circadian rhythm, the near-universal 24-hour biological clock that governs sleep and wakefulness, rest and activity, body temperature, cardiac output, and many other functions.
Mammalian cryptochrome molecules appear to be involved in the central clockwork mechanism, rather than in light-detection, he said.
http://www.hhmi.org/news/rosbash.html   (673 words)

  
 Variations in Photoreceptor Response Dynamics Across the Fly Retina -- Burton et al. 86 (2): 950 -- Journal of ...
have a higher specific conductance than other photoreceptors.
at the level of the photoreceptor for which no account exists.
all photoreceptors were absorbing light at approximately the same
http://jn.physiology.org/cgi/content/abstract/86/2/950   (426 words)

  
 Webvision: Other Plexiform Layer
Therefore, the status of the signal transmitted by the ganglion cell to the brain is essentially determined by the nature of the cone bipolar contacting it which in turn is determined by its photoreceptor synapse.
We know that photoreceptor neurotransmitter (which is glutamate, see Dowling, 1987 and Massey, 1990, for reviews) is released in the dark in the vertebrate retina (Trifonov, 1968).
Hyperpolarizing (basal junction contacting) bipolar cells are the start of OFF-center channels and the depolarizing (invaginating, ribbon-related) bipolar types are the start of ON-center channels through the whole retina and visual system.
http://webvision.med.utah.edu/OPL2.html   (2122 words)

  
 Comparative Analysis and Expression of CLUL1, a Cone Photoreceptor-Specific Gene -- Zhang et al. 44 (10): 4542 -- ...
The expression pattern of CRX is included in the retinal development blot.
In the dark-adapted retina, however, there was a change
For analysis of the developmental pattern of CLUL1 expression,
http://www.iovs.org/cgi/content/full/44/10/4542   (4304 words)

  
 Longitudinal Diffusion in Retinal Rod and Cone Outer Segment Cytoplasm: The Consequence of Cell Structure -- Holcman ...
briefly treated with collagenase and hyaluronidase, and photoreceptors
Cone photoreceptors respond to light with a change in membrane
At -40 mV holding voltage, the current was inward immediately upon achieving WCM, but slowly changed to a stationary outward value.
http://www.biophysj.org/cgi/content/full/86/4/2566   (7017 words)

  
 photoreceptor cell - definition of photoreceptor cell in the Medical dictionary - by the Free Online Medical ...
This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.
photoreceptor cell - definition of photoreceptor cell in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and Encyclopedia.
Any of the rod cells present in the retina of the eye.
http://medical-dictionary.thefreedictionary.com/photoreceptor%20cell   (94 words)

  
 Specification of the Retinal Fate of Mouse Embryonic Stem Cells by Ectopic Expression of Rx/rax, a Homeobox Gene -- ...
Subretinally transplanted embryonic stem cells rescue photoreceptor cells from degeneration in the RCS rats.
Two phases of rod photoreceptor differentiation during rat retinal development.
photoreceptor cells from degeneration in a mouse model of progressive
http://mcb.asm.org/cgi/content/full/24/10/4513   (5680 words)

  
 The Ca-activated Cl Channel and its Control in Rat Olfactory Receptor Neurons -- Reisert et al. 122 (3): 349 -- The ...
Interaction of glutamic-acid-rich proteins with the cGMP signalling pathway in rod photoreceptors.
Binding of the cGMP-gated channel to the Na/Ca-K exchanger in rod photoreceptors.
Bauer, P.J. Binding of the retinal rod Na /Ca exchanger to the cGMP-gated channel indicates local Ca -signaling in vertebrate photoreceptors.
http://www.jgp.org/cgi/content/full/122/3/349   (7805 words)

  
 Dietary 20:4n-6 and 22:6n-3 Modulates the Profile of Long- and Very-Long-Chain Fatty Acids, Rhodopsin Content, and ...
The objective of this study was to determine whether addition
content and kinetics in the developing photoreceptor cell.
ratio of 22:6n-3 is characterized by a transition in the photoreceptor
http://www.pedresearch.org/cgi/content/full/48/4/524   (4518 words)

  
 Human Usher 1B/mouse shaker-1: the retinal phenotype discrepancy explained by the presence/absence of myosin VIIA in ...
The Ankle-Link Antigen: an Epitope Sensitive to Calcium Chelation Associated with the Hair-Cell Surface and the Calycal Processes of Photoreceptors
VIIA was also found to be absent in the photoreceptor cells of other
CRB1 is essential for external limiting membrane integrity and photoreceptor morphogenesis in the mammalian retina
http://www.hmg.oupjournals.org/cgi/doi/10.1093/hmg/5.8.1171   (1255 words)

  
 Kyocera Products Imaging devices Amorphous Sillicon Photoreceptor Drum
Amorphous silicon (a-Si) photoreceptor drum has changed the idea about a photoreceptor; from a consumable component to a long life unit having a service life equivalent to that of the machine in which it is used.
In this way, the Kyocera a-Si drum makes important contributions towards the development and manufacture of environmentally friendly products.
The result is non-cartridge design that provides for toner replenishment without replacing the entire unit.
http://global.kyocera.com/prdct/ios/prd   (70 words)

  
 Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure -- ...
CRB1 is essential for external limiting membrane integrity and photoreceptor morphogenesis in the mammalian retina.
functions of Crb1, Crb2 and Crb3 in photoreceptors are not known
The Netherlands Ophthalmic Research Institute, Royal Netherlands Academy of Arts and Sciences, Meibergdreef 47, 1105 BA Amsterdam, The Netherlands
http://jcs.biologists.org/cgi/content/full/117/18/4169   (5809 words)

  
 Ion channels in health and disease: 83rd Boehringer Ingelheim Fonds International Titisee Conference -- Niemeyer et al. ...
photoreceptors, has been considered a paradigm for SOCs.
-subunit of the cone photoreceptor cGMP-gated channel are responsible for achromatopsia (ACHM3) linked to chromosome 8q21.
-subunit of the cone photoreceptor cGMP-gated cation channel.
http://emboreports.npgjournals.com/cgi/content/full/2/7/568   (3667 words)

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