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| | Phenobarbital for epilepsy |
 | | Phenobarbital is the antiepileptic drug of choice for newborns who have epilepsy. | | | Phenobarbital's effect on your thinking and state of mind is a serious drawback to using the drug. | | | Phenobarbital can alter your mood, behavior, thought processes, and ability to learn or remember things. |
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http://my.webmd.com/hw/epilepsy/hw110027.asp?lastselectedguid={5FE84E90-BC...
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| | WSAVA 2001 - Update on Bromide and Phenobarbital |
| | For 30/33 dogs (91%), serum phenobarbital concentrations were in the same therapeutic category (sub-therapeutic, low-therapeutic, mid-therapeutic, or high-therapeutic) at all time points. | | | However, in our study of 33 epileptic dogs treated chronically with phenobarbital, all dogs had an elimination half-life for phenobarbital of 14 hours or longer (median 50 hours; Levitski and Trepanier, 2000). | | | This is because the elimination half-life of phenobarbital in most dogs is much greater than 12 hours, and serum drug levels are sustained well throughout a 12-hour period. |
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http://www.vin.com/VINDBPub/SearchPB/Proceedings/PR05000/PR00194.htm
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| | Medicines for Epilepsy: Phenobarbital |
| | Phenobarbital interacts with a number of other antiepileptic drugs. | | | This is the oldest antiepileptic drug in common use. | | | It may take two weeks or more for a therapeutic level to develop. |
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http://www.epilepsyfoundation.org/answerplace/Medical/treatment/medications/typesmedicine/phenobarbital.cfm
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| | MedlinePlus Drug Information: Theophylline, Ephedrine, Guaifenesin, and Phenobarbital ( Systemic) |
| | Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; other barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. | | | In addition, one study in humans has suggested that phenobarbital taken during pregnancy may increase the chance of brain tumors in the baby. | | | Valproic acid—Using these medicines with phenobarbital may change the amount that you need to take of any of these medicines |
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http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202554.html
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| | phenobarbital |
| | Phenobarbital is habit forming, which means that you can become addicted to it. | | | Your pharmacist has more information about phenobarbital written for health professionals that you may read. | | | Before taking this medication, tell your doctor if you have ever had a drug or alcohol addiction in the past. |
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http://hw.healthdialog.com/kbase/multum/d00340a1.htm
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| | Phenobarbital (IARC Summary & Evaluation, Volume 79, 2001) |
| | Use of phenobarbital, mostly as a sedative, was associated with moderately increased risks for cancers of the lung, ovary and gall-bladder in a cohort study based on a prepaid medical care programme in the USA. | | | In several experiments in mice and rats, sequential exposure to phenobarbital with known carcinogens enhanced the incidences of hepatocellular preneoplastic foci, adenomas and carcinomas. | | | However, a nested case—control study of liver cancer with adjustment for other anti-convulsant therapy revealed no association with phenobarbital treatment. |
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http://www.inchem.org/documents/iarc/vol79/79-06.html
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| | Phenobarbital - VeterinaryPartner.com - a VIN company! |
| | Other medications which will not work as well in the presence of phenobarbital include: Lysodren(treatment for Cushing's disease), chloramphenicol(an antibiotic), corticosteroids (such as prednisone, dexamethasone), doxycycline(an antibiotic), cardiac beta-blockers, quinidine (a heart rhythm medicine), theophylline(an airway dilator), and metronidazole(a multi-purpose antibiotic/GI medicine). | | | It is effective, safe if used responsibly, and is one of the least expensive medications in all of veterinary practice. | | | Proper monitoring tests are geared for heading off such an event in plenty of time to change medication. |
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http://www.veterinarypartner.com/Content.plx?P=A&C=211&A=522&S=1
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| | Phenobarbital Level - PetPlace.com |
| | As with people, the pain experienced from a needle will vary from individual to individual. | | | So the phenobarbital blood level must be monitored carefully when used for treatment. | | | Neither sedation nor anesthesia is needed in most patients; however, some pets resent needle sticks and may need tranquilization or ultrashort anesthesia. |
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http://www.petplace.com/articles/artShow.asp?artID=3549
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| | Phenobarbital - Drugs & Vitamins - Drug Library - DrugDigest |
| | Carry an identification card with information about your condition, medications, and prescriber or health care professional. | | | Talk to your prescriber about alternatives or use of additional birth control methods while taking this drug. | | | Your prescriber or health care professional may want to gradually reduce the dose. |
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http://www.drugdigest.org/DD/DVH/Uses/0%2C3915%2C537%7CPhenobarbital%2C00.html
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| | Phenobarbital Dosage, Interactions, Side Effects, How to Use |
| | As a result, when phenobarbital is given to clients receiving such drugs, their therapeutic effectiveness may be markedly reduced or even abolished. | | | Pain is often most intense in the morning and is frequently located in the neck, shoulder girdle, and arms. | | | Miscellaneous: Pain or nerve injury at injection site, salivation, hiccups, skin rashes, shivering, skeletal muscle hyperactivity, immune hemolytic anemia with renal failure and radial nerve palsy. |
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http://www.healthdigest.org/drugs/phenobarbital.html
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| | Phenobarbital Anxiety Medication - Order Online |
| | tell your doctor and pharmacist if you are allergic to phenobarbital or any other drugs. | | | This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. | | | Do not stop taking this drug without talking to your doctor, especially if you have been taking it for a long time. |
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http://www.getmedsonline.com/phenobarbital.asp
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| | Phenobarbital, side effects, drug interactions, overdose, dosage |
| | Be sure to tell your doctor if you are in pain, or if you have constant pain, before you take phenobarbital. | | | Possible food and drug interactions when taking Phenobarbital | | | If you suspect an overdose, seek medical treatment immediately. |
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http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/phe1334.shtml
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| | Phenobarbital |
| | If you have an allergy to another barbiturate, phenobarbital, or any other part of the medicine. |
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http://www.umm.edu/altmed/ConsDrugs/Phenobarbitalcd.html
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| | Phenobarbital Linked to Lower IQ |
| | The study suggests that doctors should be careful about prescribing phenobarbital during pregnancy and that a supportive, healthy environment can go a long way toward making up for biological disadvantages, she said. | | | Two experts urged caution at interpreting the findings, saying other factors than the drug may have affected the men's intelligence in ways the study couldn't detect. | | | Phenobarbital Linked to Lower IQ Phenobarbital Linked to Lower IQ Subject: Lower IQ Linked To Drug Organization: Copyright 1995 by The Associated Press Date: Tue, 14 Nov 1995 15:50:29 PST |
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http://www.gentlebirth.org/archives/phenobrb.html
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| | Phenobarbital - PetPlace.com |
| | Most often, phenobarbital therapy in dogs is begun at 1 to 2 mg per pound (2 to 4 mg/kg) twice daily. | | | Consult with your veterinarian to determine if other drugs your pet is receiving could interact with phenobarbital. | | | Phenobarbital is a barbiturate drug with anticonvulsant properties. |
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http://petplace.netscape.com/articles/artShow.asp?artID=1538
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| | Phenobarbital prior to preterm birth for preventing neonatal periventricular haemorrhage (Cochrane Review) |
| | Phenobarbital might prevent ischaemic injury or reduce fluctuations in blood pressure and blood flow in the brain. | | | Objectives: To assess the benefits and harms of giving phenobarbital to women at risk of imminent very preterm birth with the primary aim of preventing periventricular haemorrhage in the infant. | | | These results were influenced by trials of poor quality which contributed excessive weight in the analysis due to their higher rates of severe PVH. |
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http://www.update-software.com/abstracts/AB000164.htm
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| | NIH Press Release - Study Finds Phenobarbital Fails to Prevent Brain Bleeding in Premature Infants - 08/13/1997 |
| | In all, 23 percent of the phenobarbital group (70 infants) and 23 percent of the control group (64 infants) had a brain hemorrhage. | | | "The results of our trial do not support the use of antenatal phenobarbital as prophylaxis against neonatal intracranial hemorrhage," the authors concluded. | | | A few early clinical trials and a recent meta-analysis suggested that phenobarbital would be effective in reducing the frequency and severity of brain hemorrhaging in newborns. |
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http://www.nih.gov/news/pr/aug97/nichd-13.htm
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| | Phenobarbital Induced Liver Disease |
| | Bromide is probably the anti-seizure drug of choice in dogs with liver disease. | | | Pancreatitis in epileptic dogs receiving potassium bromide therapy. | | | Effects of long-term phenobarbital treatment on the liver in dogs. |
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http://www.canine-epilepsy.com/PBLiver.html
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| | Phenobarbital of Augusta, Georgia |
| | One controlled study showed that long-term use of phenobarbital increases the breakdown of biotin. | | | Based on the currently available information, some healthcare practitioners may recommend monitoring L-carnitine blood levels or supplementing with L-carnitine. | | | Phenobarbital is occasionally used as a sedative before surgery, as a hypnotic (sleeping pill) to treat insomnia, and as an anticonvulsant to prevent and treat seizure disorders. |
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http://www.universityhealth.org/17940.cfm
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| | Phenobarbital |
| | Phenobarbital is often referred to as simply 'pheno' or 'phenobarb' and abbreviated as PB. | | | Clinical reports indicate that 60 to 80% of epileptic dogs can be controlled effectively with only PB. | | | Don't be afraid to question any medication that your dog is given. |
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http://www.canine-epilepsy.com/Phenobarbital.html
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| | Phenobarbital |
| | Plasma concentrations of 10000-30000 ng/mL are considered appropriate therapeutic levels for use as an anticonvulsant. | | | For patients on chronic phenobarbital therapy, 12-55% of the dose is excreted as the unchanged drug. | | | Epileptic patients who were taking 200 mg daily had a phenobarbital blood concentration that ranged from 16000-48000 ng/mL with an average of 29000 ng/mL. |
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| | Volume phenobarbital masturbation ejaculation |
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| | Case 2 - Auburn University - College of Veterinary Medicine |
| | Drug elimination half-life had not been previously determined for phenobarbital in this patient so a change in half-life could not be documented. | | | The increase was presumed to be due to chloramphenicol therapy. | | | Phenobarbital therapy was discontinued for one drug elimination half-life and restarted at the same dose. |
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http://www.vetmed.auburn.edu/index.pl/case_2
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| | Warnings: Serious reactions to phenobarbital |
| | Women who may become pregnant should be aware that studies have suggested a connection between phenobarbital and a higher-than-expected incidence of birth defects. | | | If you have any history of depression, drug abuse, or suicidal tendencies, be especially careful with this medicine (since depression is a side effect). | | | Finally, it's not unusual for phenobarbital to make people feel sleepy or uncoordinated. |
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http://www.nyumc.net/public_html/epilepsy_20031016/drug_therapies/phenobarbital/phe_warnings.htm
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| | Phenobarbital |
| | Phenobarbital exerts powerful influence on the active attention, reflex activity to external stimuli. | | | The injection solution is used as an anticonvulsive agent in the treatment of following conditions: epilepsy, epileptic status, convulsions, due to hyperpyrexia or overdosing of medicines, stimulating the CNS. | | | Together with potentiating of the GAFA mediation Phenobarbital depresses unselectively the action of the stimulating neuromediators and influences the neuron membrane function out of synapse zone. |
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http://www.bpg.bg/sopharma/phenobarbital.phtml
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| | WhatMeds.com - Phenobarbital |
| | An allergy or sensitivity to phenobarbital or other barbituates. | | | Phenobarbital should Not be used for people with the following medical conditions: | | | Phenobarbital may be used with caution in people with the following conditions: |
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http://www.whatmeds.com/meds/phenobarbital.html
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| | Phenobarbital |
| | A variety of information regarding drugs of abuse and drug testing concerns. | | | Find real doctors and prescriptions online at Online-Scripts.com. | | | JoltSearch is an excellent resource for quality sites on Phenobarbital and much more! |
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http://www.xnsearch.biz/phenobarbital.htm
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| | Directory of open access journals |
| | Advice was given to patients, their families, and the village authorities in order to achieve compliance. | | | METHODS: Epileptic patients were treated at home with phenobarbital at daily dosages ranging from 50 mg for children to 200 mg for adults and their condition was monitored. | | | OBJECTIVE: To assess the efficacy of phenobarbital treatment for epileptic patients in rural Mali. |
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http://www.doaj.org/abstract?id=47308&toc=y
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| | Directory of open access journals |
| | The aim of the present study was to determine if phenobarbital affects the nociception threshold. | | | We suggest that phenobarbital may mediate hyperalgesia through GABA-A receptors at supraspinal levels and antinociception through the same kind of receptors at spinal levels. | | | Formalin and abdominal constriction tests were the most sensitive procedures for the detection of hyperalgesia in response to phenobarbital compared with the tail-flick and hot-plate tests. |
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http://www.doaj.org/abstract?id=24915&toc=y
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| | What About Phenobarbital? |
| | If you’re on Donnatol (which has phenobarbital in it) and choose to use Claritin or any other medication, you need to be aware that all anti-epilepsy drugs can cause profound drug interactions. | | | It can cause profound side effects including grogginess, staggering, and rebound headaches. | | | I've looked around and it's all very interesting, but I haven't found the info on phenobarbital (curious about Claritin-d and Donnatol combined). |
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http://www.biologicalunhappiness.com/AskDoc/PhenoBrb.htm
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| | Phenobarbital - Patient UK |
| | Before taking any 'over-the-counter' medicines, check with your pharmacist which medicines are safe for you to take alongside phenobarbital. | | | Amfetamine, ecstasy) while you are being treated with phenobarbital. | | | Along with their needed effects all medicines can cause unwanted symptoms. |
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http://www.patient.co.uk/showdoc/30002996
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| | SOFT/TIAFT 98 - Determination of Butalbital, Secobarbital and Phenobarbital in A ... |
| | Forensic Toxicology Drug Testing Laboratory, Fort Meade, MD 20755, USA | | | The importance of this determination is in it providing technically and forensically supportable test results for these analytes. | | | SOFT/TIAFT 98 - Determination of Butalbital, Secobarbital and Phenobarbital in A... |
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http://www.tiaft.org/tiaft98/fri/p/f_p_24.html
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| | Pb Side Effects, and Drug Interactions - Phenobarbital - RxList Monographs |
| | Patients stabilized on anticoagulant therapy may require dosage adjustments if phenobarbital is added to or withdrawn from their dosage regimen. | | | Patients stabilized on corticosteroid therapy may require dosage adjustments if phenobarbital is added to or withdrawn from their dosage regimen. | | | Most reports of clinically significant drug interactions occurring with the barbiturates have involved phenobarbital. |
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http://www.rxlist.com/cgi/generic3/phenbarb_ad.htm
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| | Case 1 - Auburn University - College of Veterinary Medicine |
| | Response to phenobarbital was initially but 6 months into therapy, the patient has begun seizuring again. | | | Although bromide therapy could have been started in this patient, the increase in phenobarbital concentration was easier and as effective, leaving bromide available should this patient's disease get worse. | | | Induction will occur in most animals and should be anticipated by using a sufficiently high starting dose (2 mg/kg) for phenobarbital, and measuring drug concentrations at steady-state (approximately 2 weeks after therapy is begun) and then again at 3 months. |
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http://www.vetmed.auburn.edu/index.pl/case_1
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| | Phenobarbital |
| | Phenobarbital, as well as other barbiturates, is used only for short-term treatment of insomnia. | | | As with older patients, infants and children are sensitive to the effects of phenobarbital. | | | Barbiturates such as phenobarbital act as powerful sedatives by reducing activity in the central nervous system (the brain and spinal cord). |
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http://www.wholehealthmd.com/refshelf/drugs_view/1,1524,494,00.html
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| | Phenobarbital >>> Peanuts |
| | MAO inhibitors may increase the effect of this drug. | | | Molindone may increase the Antihistamine effect of this drug. | | | Phenobarbital Oral Anticoagulants may decrease the effect of this drug. |
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http://farmac.pisem.net/Phenobarbital.htm
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| | phenobarbital |
| | Phenobarbital may be substituted for other barbiturates as a method of decreasing the incidence of withdrawal symptoms while weaning patients off barbiturates. | | | Use with caution in patients with pulmonary, cardiovascular, hepatic or renal insufficiency. | | | Hypoglycemic seizures should be treated with glucose, not phenobarbital, which will not resolve the hypoglycemic state or prevent CNS injury. |
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http://www.templejc.edu/dept/ems/drugs/phenobarbital.html
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| | Phenobarbital (Luminal®), Serum |
| | Phenobarbital can affect the metabolism of phenytoin, ethosuximide, and increase the clearance and elimination of chloramphenicol, theophylline, oral anticoagulants (warfarin), cyclosporine, and oral contraceptives; where appropriate, the use of these drugs in patients on phenobarbital should be monitored clinically and through the laboratory. | | | Phenobarbital frequently is used in the treatment of neonatal seizures and may be the initial drug employed in young children. | | | However, because of increasing concern about adverse neuropsychological reactions to sedative/hypnotic antiepileptic drugs, many neurologists prefer less sedating drugs, such as carbamazepine, phenytoin, or valproate. |
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http://www.labcorp.com/datasets/labcorp/html/chapter/mono/td035900.htm
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| | Phenobarbital |
| | Dose related - These side effects might be experienced when phenobarbital is first initiated or when doses are changed, but may be reduced as you continue to take this medication. | | | Using phenobarbital with certain other medications may alter the activity of either drug which can lead to ineffective seizure control or side effects. | | | Phenobarbital is a barbiturate with anticonvulsant effects used to treat and prevent seizures except for absence (petit mal). |
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http://www.uic.edu/pharmacy/epilepsy/phenobar.htm
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| | Phenobarbital - references in online news media |
| | Many pets with epilepsy are drugged up with bromides or phenobarbital (and have potential secondary liver problems). | | | The patient received phenobarbital for seizure prophylaxis at that time and experienced no further seizure activity. | | | Although phenobarbital is used most commonly for symptomatic management of neonatal withdrawal, he suggests that pharmacologically "it would make more sense to... |
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http://www.linkmorgue.org/DRUGS/nov03-nov04/Phenobarbital.html
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| | Phenobarbital |
| | Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. | | | Although this use is not included in product labeling, phenobarbital is used in certain patients with the following medical condition: | | | Sedative-hypnotic—Amobarbital; Aprobarbital; Butabarbital; Pentobarbital; Phenobarbital (parenteral only); Secobarbital |
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| | Reducing Phenobarbital |
| | If there are no seizures after 6 months of combination therapy, I often try to decrease the phenobarbital further. | | | For dogs on bromide and phenobarbital, I usually aim for a phenobarbital level of about 25 mcg/ml. | | | Remember that if you change the dose of phenobarbital it takes about 10 to 14 days for the blood level to equalize at the new level. |
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http://www.canine-epilepsy-guardian-angels.com/ReducingPb.htm
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| | The World Factbook 2004 - Notes and Definitions |
| | Depressants (sedatives) are drugs that reduce tension and anxiety and include chloral hydrate, barbiturates (Amytal, Nembutal, Seconal, phenobarbital), benzodiazepines (Librium, Valium), methaqualone (Quaalude), glutethimide (Doriden), and others (Equanil, Placidyl, Valmid). |
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http://www.brainyatlas.com/docs/notesanddefs.html
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| | Encyclopedia: Phenobarbital |
| | {Amobarbital} {Aprobarbital} {Phenobarbital} {Butabarbital} {Butalbital} {Hexobarbital} {Mephobarbital} {Pentobarbital} {Secobarbital} {Sodium thiopental} {Talbutal} {Thiobarbital} Barbiturates are drugs that acts as central nervous system (CNS) depressants, and by virtue of this they produce a wide spectrum of effects, from mild sedation to anesthesia. | | | It is a barbiturate used as a drug for its hypnotic, sedative, and anticonvulsant properties. | | | Primidone, is an anticonvulsant of the pyrimidinedione class whose active metabolites, phenobarbital (minor) and phenylethylmalonamide (PEMA) (major), are also anticonvulsants. |
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http://www.nationmaster.com/encyclopedia/Phenobarbital
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| | Pb Online, Description, Chemistry, Ingredients - Phenobarbital - RxList Monographs |
| | Phenobarbital is a barbiturate, nonselective central nervous system depressant which is primarily used as a sedative hypnotic and also as an anticonvulsant in subhypnotic doses. | | | Barbiturates are substituted pyrimidine derivatives in which the basic structure common to these drugs is barbituric acid, a substance which has no central nervous system (CNS) activity. | | | Pb Online, Description, Chemistry, Ingredients - Phenobarbital - RxList Monographs |
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| | Phenobarbital (PB) dosing confusion |
| | Phenobarbital also comes in 8, 15, 16, 30, 32, 60, 65, and 100 milligram tablets. | | | There is a phenobarbital elixir which contains 15 mg./5 ml. | | | The reason for this confusion is the difference in weight measurement used by different pharmaceutical companies. |
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http://www.canine-epilepsy-guardian-angels.com/PB_dosing_confusion.htm
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