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| | Repeated Phencyclidine Treatment Induces Negative Symptom-like Behavior in Forced Swimming Test in Mice: Imbalance of ... |
 | | Steinpreis RE (1996): The behavioral and neurochemical effects of phencyclidine in humans and animals: Some implications for modeling psychosis. | | | These results suggest that the enhanced effect of PCP on the immobility is mediated by imbalance of 5-HTergic and dopaminergic systems in the prefrontal cortex and could be used as a model of the negative symptoms of schizophrenia. | | | Castellani S, Adams PM (1981): Acute and chronic phencyclidine effects on locomotor activity, stereotypy and ataxia in rats. |
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http://www.nature.com/npp/journal/v23/n4/full/1395546a.html
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| | PHENCYCLIDINE AND RELATED ARYLCYCLOHEXYLAMINES |
| | Electroencephalographic and Overt Behavioral Effects of Phencyclidine and Two of Its Metabolites in Macaca Mulatta | | | Phencyclidine Studies in the Dog: Pharmacology of PCP, Profiles of Eight Analogues Abused by Man and the Similarity of PCP to the opioid NANM (N-Allylnormeta- zocine or SKF | | | Effects of Dopaminergic, Cholinergic and Opiate Agents on phencyclidine-Induced Behaviors in the Rat |
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http://www.nppbooks.com/phencyclidine_and_related_arylcy.htm
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| | The Effect of Rate of Drug Administration on the Extent and Time Course of Phencyclidine Distribution in Rat Brain, ... |
| | Garey RE and Heath RG (1976) The effects of phencyclidine on the uptake of 3H-catecholamines by rat striatal and hypothalamic synaptosomes. | | | Smith RC, Meltzer HY, Arora RC and Davis JM (1977) Effects of phencyclidine on [3H]catecholamine and [3H]serotonin uptake in synaptosomal preparations from rat brain. | | | Johnson KM and Jones SM (1990) Neuropharmacology of phencyclidine: Basic mechanisms and therapeutic potential. |
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http://dmd.aspetjournals.org/cgi/content/full/28/7/742
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| | PCP and Violence |
| | Both aspects concern the relationship between phencyclidine abuse and aggressive behavior. | | | (1982) found no difference in the behavior of clients admitted for phencyclidine detoxification and those admitted for opioid detoxification. | | | 1988), indicate that if phencyclidine induces violent, criminal behavior, it does so only extremely infrequently. |
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http://www.druglibrary.org/schaffer/MISC/pcpviol.htm
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| | Subchronic Phencyclidine Administration Reduces Mesoprefrontal Dopamine Utilization and Impairs Prefrontal ... |
| | In the presently described series of experiments, the neurochemical and cognitive consequences of subchronic phencyclidine administration in the rat were explored. | | | These biochemical and behavioral data show that repeated phencyclidine administration induces prefrontal cortical cognitive deficits in rats, as in humans, and offer a biochemical perspective of the neural substrate underlying this cognitive impairment: inhibition of mesocortical dopamine neurons. | | | Keywords: Cognition; Dopamine; Phencyclidine; Prefrontal cortex; Psychotomimetic; Rat; Working memory; Schizophrenia; Utilization |
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http://www.nature.com/npp/journal/v17/n2/abs/1380572a.html
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| | The Virtual Hospital: Clinical Psychopharmacology Seminar 1996-1997: Phencyclidine Intoxication |
| | Generally, the behavioral effects of PCP are the most commonly encountered severe complication and appear to be responsible for the majority of deaths, i.e., drownings (Burns and Lerner 1978, Reynolds 1976), automobile accidents (Reynolds 1976), and suicides (Burns and Lerner 1976, Burns and Lerner 1978), associated with PCP ingestion. | | | The infamous reputation attributed to PCP by inexperienced users seems to have resulted in the distribution of the drug under a wide variety of "street" names as well as the marketing practice of misrepresenting this agent for other more commonly sought street drugs (Burns and Lerner 1976, Fauman et al 1976). | | | Comparison of haloperidol and chlorpromazine in the treatment of phencyclidine psychosis. |
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http://www.janela1.com/vh/docs/v0002513.htm
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| | Synonyms of phencyclidine |
| | phencyclidine, phencyclidine hydrochloride, PCP, angel dust, hallucinogen, hallucinogenic drug, psychedelic drug, psychodelic drug |
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http://www.infoplease.com/thesaurus/phencyclidine
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| | eMedicine - Toxicity, Phencyclidine : Article by Robert S Helman, MD |
| | Medicine is a constantly changing science and not all therapies are clearly established. | | | McCarron MM, Schulze BW, Thompson GA, et al: Acute phencyclidine intoxication: incidence of clinical findings in 1,000 cases. | | | You are in: eMedicine Specialties > Medicine, Ob/Gyn, Psychiatry, and Surgery > Critical Care |
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http://www.emedicine.com/med/topic1813.htm
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| | Immunoassay for phencyclidine - Patent 4196185 |
| | Phencyclidine is an anesthetic which is medicinally useful only in veterinary application. | | | The ingestion of 1 mg or "snorting" of 1-3 mg can produce physiological changes. | | | The illicit use of phencyclidine in humans produces symptoms ranging from confusion, disorientation, stupor, and coma to death in cases of overdose. |
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http://www.freepatentsonline.com/4196185.html
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| | Drugs and Human Performance FACT SHEETS - Phencyclidine (PCP) |
| | Malizia E, Borgo S, Andreucci G. Behavioral symptomatology indicative of cannabinoids or phencyclidine intoxication in man. Riv Toss Sperim Clin 1984;14(1-2):87-95. | | | McCarron MM, Schulze BW, Thompson GA. Acute phencyclidine intoxication: Incidence of clinical findings in 1,000 cases. | | | Characteristics of 68 chronic phencyclidine abusers who sought treatment. |
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http://www.nhtsa.dot.gov/people/injury/research/job185drugs/phencyclidine.htm
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| | Rapid Phencyclidine PCP Test |
| | Clinical consideration and professional judgment should be applied to all test results, particularly when preliminary positive results are indicated. | | | Note: Any positive test should be confirmed using quantitative methods by a qualified healthcare professional. | | | This is the preferred scientific method for qualitative assay. |
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http://www.craigmedical.com/PCP.htm
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| | PCP |
| | PCP became widely used in America in the 70's as a street drug, it is quite a rare drug in the UK. | | | Phencyclidine or PCP for short is a synthetic drug with stimulant and hallucinogenic properties. |
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http://www.homehealth-uk.com/medical/pcp.htm
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| | Lycaeum > Leda > Phencyclidine: pharmacology and toxicology |
| | Comparison of Phencyclidine Hydrochloride (Sernyl) with Other Drugs. | | | Clinical Trial of Phencyclidine (Sernyl) in Patients with Psychoneurosis. | | | Phencyclidine (PCP): A Street Drug in the Laboratory. |
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http://leda.lycaeum.org/?ID=12989
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| | InfoFacts - PCP (Phencyclidine) |
| | It has been used in veterinary medicine but was never approved for human use because of problems that arose during clinical studies, including delirium and extreme agitation experienced by patients emerging from anesthesia. | | | PCP (phencyclidine) was developed in the 1950s as an intravenous anesthetic. | | | The National Institute on Drug Abuse (NIDA) is part of the National Institutes of Health (NIH), a component of the U.S. Department of Health and Human Services. |
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http://www.nida.nih.gov/Infofax/pcp.html
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| | Phencyclidine-induced bizarre pattern of locomotor activity and stereotypy |
| | These behaviours are recorded individually for rats in Opto-Varmiex cages and the ability of drugs to reduce these behaviours is measured. | | | Keywords: schizophrenia, stereotypy, positive symptoms, negative symptoms, psychosis, antipsychotics, neuroleptics, rat, phencyclidine, locomotor hyperactivity, sensitisation, stereotypy, in vivo | | | Phencyclidine (PCP) is a psychotomimetic compound that can induce a schizophrenia-like psychosis in man. In rats phencyclidine produces locomotor hyperactivity and steretyped behaviour that can be inhibited by antipsychotic drugs. |
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http://www.sams-dodd.com/tds/T-G00017-00000.html
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| | PCP Or Phencyclidine As A Recreational Drug |
| | From it's first synthesis as a surgical anesthetic to veterinary anesthetic to street drug. | | | Phencyclidine users sometimes experience flashbacks, but unlike LSD flashbacks, which are psychological in origin, PCP after shocks are physically-based and involve actual drug effects. | | | Describes the chemical properties of phencyclidine, the physical and psychological effects of this hallucinogen, and more. |
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http://www.a1b2c3.com/drugs/pcp2.htm
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| | BehaveNet® Clinical Capsule: Phencyclidine Intoxication |
| | Clinically significant maladaptive behavioral changes (e.g., belligerence, assaultiveness, impulsiveness, unpredictability, psychomotor agitation, impaired judgment, or impaired social or occupational functioning) that developed during, or shortly after, phencyclidine use. | | | Dysfunctional changes in physiological functioning, psychological functioning, mood state, cognitive process, or all of these, as a consequence of consumption of [phencyclidine]; usually disruptive, and often stemming from central nervous system impairment.* | | | Recent use of phencyclidine (or a related substance). |
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http://www.behavenet.com/capsules/disorders/phencyclidineintoxication.htm
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| | TMS Labs Phencyclidine Test Cassette |
| | For a book on how to treat teens with drug use problems, click here. | | | Self-injurious behavior is one of the devastating effects of Phencyclidine. | | | 5 Phencyclidine is excreted in the urine as an unchanged drug (4 to 19%) and conjugated metabolites (25 to 30%).6 |
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http://www.testsymptomsathome.com/aco1p.asp
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| | Phencyclidine (PCP), Urine |
| | Petersen RC and Stillman RD, "Phencyclidine: A Review," Hosp Formul, 1979, 14:334-44. | | | Wessinger WD and Owens SM, "Phencyclidine Dependence: The Relationship of Dose and Serum Concentrations to Operant Behavioral Effects," J Pharmacol Exp Ther, 1991, 258(1):207-15. | | | Phencyclidine is most often called "angel dust." It was first developed as an anesthetic in the 1950s. |
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http://www.labcorp.com/datasets/labcorp/html/chapter/mono/fo002100.htm
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| | DEA Briefs & Background, Drugs and Drug Abuse, Drug Descriptions, Phencyclidine (PCP) & Related Drugs |
| | DEA Briefs and Background, Drugs and Drug Abuse, Drug Descriptions, Phencyclidine (PCP) and Related Drugs | | | PCP use is associated with a number of risks and many believe it to be one of the most dangerous drugs of abuse. | | | Originally designed as a human anesthetic and later produced only as a veterinary anesthetic, PCP is no longer produced or used for legitimate purposes. |
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http://www.usdoj.gov/dea/concern/pcp.html
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| | Phencyclidine Drug Tests - $5.95... For the Drug PCP. |
| | The results demonstrate that varying ranges of urinary specific gravity does not affect the test results. | | | The results demonstrate that varying ranges of pH does not interfere with the performance of the test. | | | A side-by-side comparison was conducted using the PCP One Step Phencyclidine Test Device and a leading commercially available PCP rapid test. |
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http://www.drugtestsuccess.com/instantdrugtest-1p-pcp2.htm
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| | GDCADA PCP - Facts and Statistics |
| | Phencyclidine (PCP) was developed in the 1950s as an intravenous anesthetic. | | | Use of PCP in humans was discontinued in 1965, because it was found that patients often became agitated, delusional, and irrational while recovering from its anesthetic effects. |
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http://www.gdcada.org/statistics/pcp.htm
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| | Characteristics of Primary Phencyclidine (PCP) Admissions: 2001 |
| | Phencyclidine (PCP) was originally developed as an anesthetic in the 1950s. | | | Its medical use was discontinued in 1965 because of its dangerous psychological side effects, but illicit use of this addictive drug has remained a problem. | | | SAMHSA, an agency in the Department of Health and Human Services, is the Federal Government's lead agency for improving the quality and availability of substance abuse prevention, addiction treatment, and mental health services in the United States. |
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http://oas.samhsa.gov/2k4/PCPtx/PCPtx.htm
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| | Phencyclidine - Wikipedia, the free encyclopedia |
| | National Institute of Drug Abuse InfoFacts: PCP (Phencyclidine) | | | The Straight Dope: Does PCP turn people into cannibals? | | | Phencyclidine (a contraction of the chemical name phenylcyclohexylpiperidine; also called PCP, sherm, angel dust, embalming fluid, Wet, or Sugar) is a dissociative psychedelic drug formerly used as an anaesthetic agent, exhibiting hallucinogenic effects. |
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http://en.wikipedia.org/wiki/Phencyclidine
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| | Phencyclidine-induced impairment of sensorimotor gating |
| | R.S. Mansbach M.A. Geyer, Effects of phencyclidine and phencyclidine biologs on sensorimotor gating in the rat, Neuropsychopharmacology 2 (1989) 299-308. | | | Keywords: psychosis, schizophrenia, information processing, sensory integration, pre-pulse inhibition, positive and negative symptoms, in vivo, phencyclidine, clozapine, neuroleptics, antipsychotics | | | Senorimotor gating is measured in humans and experimental animals in paradigm called prepulse induced inhibition of the acoustic startle response (PPI) which is based on the ability for a small acoustic pre-stimulus to reduce the response to a subsequent larger stimulus of the same modality. |
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http://www.sams-dodd.com/tds/T-G00013-00000.html
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| | PHENCYCLIDINE |
| | PCP or Phencyclidine, is a single drug that forms a distinct category of its own, because the effects it produces are unlike those of any category. | | | In some respects, PCP acts like an hallucinogen; and, it is frequently classed as an hallucinogen in medical texts and scientific / research reports. | | | The formal chemical name for this drug is Phenyl Cyclohexyl Piperidine, from which the initials PCP are derived. |
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http://www.sayno.com/pcp.html
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| | IngentaConnect Prenatal Phencyclidine Induces Heightened Neurodegeneration in Ra... |
| | Phencyclidine administered to the developing rat brain at high doses for a few hours during late foetal life induces apoptotic neurodegeneration in several brain regions. | | | Thus, prenatal exposure to phencyclidine can have either neurodegenerative or antiapototic effects depending upon brain region, and there is a discrepancy between persisting behavioural deficits and amount of cell loss for time of maximal prenatal effect of the drug. | | | Prenatal Phencyclidine Induces Heightened Neurodegeneration in Rats in some Brain Regions, Especially during 2nd Trimester, but Possible Anti-Apoptotic Effects in Others |
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http://www.ingentaconnect.com/content/mksg/pto/2002/00000090/00000001/art00006
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| | Phencyclidine Dependence |
| | Phencyclidine abuse: A destructive pattern of phencyclidine use, leading to significant social, occupational, or medical impairment. | | | Continued using phencyclidine despite knowing it caused significant problems: Continued phencyclidine use is continued despite knowledge of having a persistent or recurrent physical or psychological problem that is likely to have been worsened by phencyclidine | | | Phencyclidine caused reduction in social, occupational or recreational activities: Important social, occupational, or recreational activities given up or reduced because of phencyclidine use. |
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http://www.psychologynet.org/pcp.html
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| | PCP |
| | PCP (phencyclidine) is classified as a hallucinogen and has many of the same effects as LSD, but can be much more dangerous. | | | In the 1950's, PCP was investigated as an anesthetic, but due to its severe side effects, its development for human use was discontinued. |
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http://www.streetdrugs.org/pcp.htm
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| | Erowid Library/Bookstore : 'Phencyclidine: Angel Dust' |
| | Dr. Hafen, a specialist in the field of drug education for 16 years, carefully delineates the drug's history, pharmacology an effects. | | | "Phencyclidine" provides the reader with a definitiev analysis of the unpredictable drug more commonly referred to as PC or "Angel Dust". |
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http://www.erowid.org/library/books/phencyclidine_angel.shtml
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| | Drug Test Drug Abuse Phencyclidine (PCP) |
| | In the 1950s, phencyclidine was investigated as an anesthetic but, due to the side effects of confusion and delirium, its development for human use was discontinued. | | | Telazol®, a Schedule III veterinary anesthetic containing tiletamine (a PCP analogue), in combination with zolazepam, (a benzodiazepine), is sporadically encountered as a drug of abuse. | | | Phencyclidine (PCP), a clandestinely manufactured hallucinogen commonly used in conjunction with marijuana, causes users to feel detached from their surroundings and, in some cases, paranoid and violent. |
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http://www.drugtestcenter.com/content1/glossary/pcp.html
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| | Search Results for phencyclidine - Encyclopædia Britannica |
| | A proposed new treatment for schizophrenia, based on neuroscience research in the U.S., lacked the disadvantages of currently used drugs. | | | Mind-altering drugs commonly abused include amphetamines, cocaine, phencyclidine, heroin, and methaqualone. | | | PCP was first developed in 1956 by Parke Davis Laboratories of Detroit, Mich., for use as an... |
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http://www.britannica.com/search?query=phencyclidine&submit=Find&source=MWTAB
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| | Expomed Drug Testing For The Detection of Phencyclindine (PCP) in Urine. |
| | Depending on the amount used, the user may show signs of euphoria, relaxation, increased strength, time and space distortions, anxiety, panic, and hallucination. | | | Phencyclidine, commonly known as PCP or "angel dust," is used primarily as a recreational drug for its hallucinogenic effects. | | | The cutoff concentration for this test is 25 ng/ml, as recommended by the Substance Abuse and Mental Health Services Administration (SAMHSA) (NIDA). |
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http://www.expomed.com/drugtest/phencycl.htm
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| | PCP (phencyclidine hydrochloride) |
| | PCP (phencyclidine hydrochloride), also called angel dust, ozone, wack, and rocket fuel, is a drug used to achieve an altered state of consciousness and hallucinations. | | | Frequent use of PCP, which is illegal in the United States, can cause drug addiction. |
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http://www.webmd.com/hw/health_guide_atoz/aa75852.asp
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| | PHENCYCLIDINE |
| | Effects: The effects of Phencyclidine use include agitation, delusions, vomiting, loss of balance, drooling, irrational behavior, increased respiratory rate, blood pressure and pulse, as well as illusions and hallucinations. | | | History: Phencyclidine was developed in the 1950's for use as an intravenous anesthetic for humans, until it was banned in 1965. | | | Identification: Phencyclidine is a white crystalline powder that can is snorted, smoked or swallowed. |
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http://www.seshca.com/phencyclidine.htm
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| | The determination of phencyclidine in meconium using ion trap mass spectrometry |
| | Because of the small amount often collected, the sensitivity of analytical assay is extremely important. | | | It is particularly useful for the analysis of meconium in which sample size is limited and sensitivity is an important factor. | | | forensic science, mass spectrometry, meconium, meconium drug testing, phencyclidine, toxicology |
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http://www.astm.org/JOURNALS/FORENSIC/PAGES/2741.htm
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| | Sudden Death During Arrest and Phencyclidine Intoxication |
| | phencyclidine's pharmacologic properties do not frequently cause significant neurologic or cardiorespiratory changes that may lead to sudden unexpected death during arrest. | | | Most cases of sudden death during arrest have involved cocaine intoxication; because phencyclidine's pharmacologic properties are quite different from those of cocaine, these cases allow for comparisons to those factors that may have greater importance. | | | "In this article, we review the deaths of 2 individuals in which phencyclidine intoxication was a factor that contributed to death during arrest. |
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http://www.charlydmiller.com/LIB04/2003phencyclidinera.html
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| | Alibris: Phencyclidine |
| | Also discusses the physical and psychological effects of this hallucinogen which can cause serious mental illness and even death. | | | Also provides sources of further information and help. | | | Describes the chemical properties of phencyclidine or PCP and its original use as a pre-surgery anesthetic. |
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http://www.alibris.com/search/books/subject/Phencyclidine
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| | Semisonic Message Boards - phencyclidine |
| | Maybe phencyclidine is some kind of twelve-hour flu? | | | Hey Donna, I don't know what that is. I have never heard of phencyclidine but it's weird because I think I may have it. | | | This has been going on for about ten hours. |
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http://www.semisonic.com/forums/topic.asp?TOPIC_ID=1755
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| | L E G A L H I G H S |
| | Effects: Euphoriant affecting CNS in a manner similar to PCP (phencyclidine), accompanied with mental changes like those from smoking hashish. | | | Contraindications: Although a central depressant, in some individuals it may cause nervousness. | | | Material: Synthetic chemical prepared by reacting chloral with glucose under heat. |
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http://www.entheogen.st/legal.html
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| | Phencyclidine - definition of Phencyclidine in Encyclopedia |
| | Phencyclidine (also called PCP or Angel dust) is a dissociative/anaesthetic developed in the 1960s by Parke & Davis pharmaceutical company. | | | Embed a dictionary search in your own web page |
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http://encyclopedia.laborlawtalk.com/Phencyclidine
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| | Resource Library: Find information on Phencyclidine overdose at MerckSource |
| | This is poisoning from an overdose of phencyclidine. | | | The manufacture of a product generally has the most complete information about that product. | | | Note: This list may not be all inclusive. |
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http://www.mercksource.com/pp/us/cns/cns_hl_adam.jspzQzpgzEzzSzppdocszSzuszSzcnszSzcontentzSzadamzSzencyzSzarticlezSz002526zPzhtm
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| | PCP Drug Test - $5.95... For Phencyclidine - Angel's Dust. |
| | A study was conducted to determine the cross-reactivity of the test with compounds in either drug-free urine or Phencyclidine positive urine. | | | The following compounds show no cross-reactivity when tested with the PCP One Step Phencyclidine Test Device at a concentration of 100,000 ng/mL: | | | The following table lists compounds and their respective cutoff concentrations in urine that yield a positive result (cross-react) with the PCP One Step Phencyclidine Test Device at 5 minutes: |
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http://www.drugtestsuccess.com/instantdrugtest-1p-pcp.htm
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| | Certification of Phencyclidine in Lyophilized Human Urine Reference Materials |
| | One of these materials is standard reference material (SRM) 1511, Multidrugs of Abuse in Freeze-dried Urine, and the other material is a CAP PCP RM. | | | Certification of Phencyclidine in Lyophilized Human Urine Reference Materials | | | The National Institute of Standards and Technology (formerly the National Bureau of Standards), in cooperation with the College of American Pathologists (CAP), has certified the concentrations of phencyclidine (PCP) in two new reference materials (RMs). |
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http://www.jatox.com/abstracts/1996/jan-feb/43-tai.htm
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| | Tucker Max Message Board - View Profile: Phencyclidine |
| | Phencyclidine is not a member of any public groups | | | The only NOW here is when you're going to get me another beer. | | | Tucker Max Message Board - View Profile: Phencyclidine |
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http://messageboard.tuckermax.com/member.php?u=8822
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| | Publications on Phencyclidine (PCP) |
| | DASIS Report: Characteristics of Primary Phencyclidine (PCP) Admissions: 2001 (May 7, 2004) | | | To order by phone, call SAMHSA's NCADI at (800) 729-6686 and ask for the corresponding item number. |
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http://store.health.org/catalog/results.aspx?h=drugs&topic=58
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| | PPC - Free Encyclopedia |
| | In chemistry, PPC is short for the chemical compound 4-phenyl-4-(1-piperidinyl)-cyclohexanol, a metabolite product of Phencyclidine (PCP). |
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http://www.wacklepedia.com/p/pp/ppc.html
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