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| | Bacteriophage Ecology Group — Phage Therapy References |
 | | Phage therapy: a reappraisal of bacteriophages as antibiotics. | | | Phage therapy is complicated by the self-replicating nature of phage. | | | Phage therapy in the agricultural, food-processing and fishery industries is already being successfully applied, and this review, whilst being aware of the potential drawbacks, emphasizes the need for further carefully controlled empirical data on its efficacy and safety in treating human and animal disease, especially in view of its numerous advantages over antibiotics. |
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http://www.phage.org/bib_pt.htm
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| | Biotechnology and Development Monitor, No. 39, p. 14-17. |
| | Phages will not be the panacea of medicine, but phage therapy research will gain momentum because traditional antibiotic research has come to a stop. | | | Phage therapy is especially interesting for medical care in developing countries. | | | On the other hand, phage therapy has proved to be effective against dysentery since the first days of phage therapy research. |
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http://www.biotech-monitor.nl/3905.htm
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| | Mediscover Infectious Diseases |
| | Although support for phage therapy gradually disappeared in most parts of the world, key centers in Tbilisi, Georgia and Wroclaw, Poland continued their research in response to concerns over the increasing incidence of nosocomial infections and bacteria resistant to most or all known antibiotics. | | | Then, with the advent of the antibiotic era, efforts to characterize phage therapy were widely abandoned. | | | Today, as the spread of antibiotic resistance reaches crisis point, should the window of opportunity for phage therapy be opened a second time? |
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http://www.mediscover.net/Articledet.cfm?ArticleID=54
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| | Division M HomePhage |
| | An underlying assumption (and justification) of the early phage molecular biologists was that the principles of life that could be learned from phages would also apply to other forms of life. | | | At the same time, the number of biological researchers using some form of phage in their research has increased substantially, since many of the tools of modern molecular biological research are phages or phage-derived (see The Practical Phage, below). | | | As it has become clear in subsequent decades just how remarkably correct that assumption was, it has become similarly clear that the history of phage biology is a major and essential part of the modern history of biology as a whole. |
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http://www.asm.org/division/m/M.html
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| | Phage Therapy Links |
| | The foundation's purpose is to foster communication and research related to phage biology and its practical applications, including phage therapy. | | | This is the article that fueled most of those to come after--it begins with a quote from Sinclair Lewis's Arrowsmith, goes through the field of phage therapy from the 1930's to present, and re-introduced the Eliava Institute in The Republic of Georgia and their phage research to the Western world. | | | A nice collection of information about phages in general, including a list of scientists who work with phages, phage graphics and an extensive list of journal references and abstracts about phage therapy (careful, some LARGE files which may take a while to view). |
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http://www.phagetherapy.com/ptlinks.html
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| | Phenomena, Comment and Notes - The Return of the Phage |
| | The work also helped researchers understand the shortcomings of phage therapy of the past. | | | Whatever the future, phages have already earned a respected place in the annals of medicine. | | | Worldwide, up to 60 percent of hospital-acquired infections turn out to be drug-resistant. |
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http://www.smithsonianmag.si.edu/smithsonian/issues00/oct00/phenom_oct00.html
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| | ASCRC strategy |
| | In Australia, this strain selection exercise was carried out in the private laboratories of each factory, and its success was largely dependent upon the standard of laboratory conditions and the technical skill of the laboratory personnel [3]. | | | The transfer of such plasmids (for example, pMU1311 [12] and pNP40 [4]) between strains is an entirely natural mating event, and is increasingly being exploited world-wide for construction of starter strains with enhanced resistance to bacteriophage infection. | | | Within the range of appropriate strains available, ASCRC does not dictate the final choice of strains. |
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http://ascrc.com.au/strategy.html
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| | IITD PAN - Wroc³aw |
| | The Center for Phage Therapy will open at our Institute later this year. | | | [15.06.2005] Institutional Review Board (Bioethics Commission) approves experimental phage therapy in patients to be carried out at the Institute | | | preparation of phage lysates for a therapeutic treatment. |
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http://surfer.iitd.pan.wroc.pl/phages/phages.html
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| | Bacteriophage Ecology Group - Links |
| | Turn of a Phrase Section: Phage Therapy (Wide World of Words) | | | Antibacterial therapy may only be a phage away | | | Phage therapy: The peculiar kinetics of self-replicating pharmaceuticals |
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http://www.mansfield.ohio-state.edu/~sabedon/beg_links.htm
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| | July 21, 2000, Hour One: Phage Therapy |
| | And now that strains of bacteria resistant to standard antibiotics are on the rise, the idea of phage therapy has been getting more attention in the worldwide medical community. | | | Doctors used phages as medical treatment for illnesses ranging from cholera to typhoid fevers. | | | On this hour of Science Friday, we'll take a look at the current state of phage research, talk about what progress has been made in phage therapy, and about whether it may be a viable medical option in the near future. |
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http://www.sciencefriday.com/pages/2000/Jul/hour1_072100.html
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| | Bacteriophage |
| | This decision, while appearing correct at the time, has been criticised since because it led to the neglect of some other important aspects of bacteriophage biology, most notably lysogeny. | | | The phage is still present in the cell as a prophage and under certain conditions, such as UV irradiation, it becomes active and resumes a lytic growth cycle. | | | This conversion is the major reason for the great utility of these phage as a molecular biological laboratory tool: they provide an easy means to prepare ssDNA for DNA sequencing. |
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http://www.mun.ca/biochem/courses/3107/Lectures/Topics/bacteriophage.html
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| | [ p h a g e ] v i r u s |
| | [phage] allows the user to experience his or her computer memory as a palimpsest of his or her own life experiences rather than know the computer as simply a tool for daily use. | | | The title of [phage] plays upon the coded word "virus"-- referring to a bacteriophage, a constructive human virus that preys on harmful bacteria. | | | It eradicates gender-based notions previously associated with the life creating process, and it questions the command and control paradigms which created the computer in the first place. |
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http://www.maryflanagan.com/virus.htm
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| | The T-Phage Page |
| | The Bacteriophage Ecology Group is an organization of bacteriophage ecologists. | | | The phage art gallary is also a riot. | | | For each one T-phage which sacrifices itself, 50 more T-phages come into being to do the same. |
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http://www.zeuscat.com/andrew/personal/info/tphage
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| | PHENOTYPIC CONVERSIONS AS A RESULT OF PSEUDOLYSOGENY |
| | Nida SK, Ferretti JJ (1982) Phage influence on the synthesis of extracellular toxins in Group A Streptococci. | | | Based on the potential role of pseudolysogens in nature, we have taken initiated investigations of the interactions between bacterium and phage that result in pseudolysogenic interactions. | | | This leads to both infected and phage sensitive progeny in the same culture. |
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http://nbiap.biochem.vt.edu/brarg/brasym95/shaffer95.htm
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| | phage_intro |
| | T-even phage tails have a contractile sheath and function "like a syringe". | | | The "head and tail" morphology of some is unique to phages and not found among other groups of viruses and is related to their mode of cell penetration. | | | Two classical experiments reveal the processes involved in phage replication: |
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http://www.biosci.ohio-state.edu/%7Emgonzalez/Micro521/Lambda/phage_intro.html
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| | Bacteriophage Replication |
| | The fact that the life-cycle of filamentous phage such as M13 includes both a ssDNA phase and a dsDNA phase has been very useful for molecular biologists. | | | Bacteriophage M13 (and other filamentous phage like it) has a circular ssDNA molecule in the capsid. | | | After adsorption of the phage to the bacterial cell surface and injection into the cell, the chromosome circularizes by means of these complementary cohesive ends. |
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http://www.mun.ca/biochem/courses/3107/Lectures/Topics/bacteriophage_replication.html
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| | About Georgian Academy of Sciences |
| | A number of original phage typing patterns have been elaborated for epidemiology studies, in particular, Salmonella typhimurium, Salmonella typhi, Salmonella paratyphy A,B, Sshigella, Proteus, Yersinia. | | | a)Therapeutic bacteriophages (phages) for treatment and prophylactics of different human and animal bacterial diseases, such as: Staphylococcus, Streptococcus, E. coli, Pseudomonas, Proteus, Salmonalla, Shigella, Serratia, Klebsialla, Enterobacter, Campilobacter, Yersinia, Brucella, etc. Most of these phage have been widely applied in clinics throughout the former Soviet Union. | | | The patterns are destined for identification of source of infection routs of its spread in environment. |
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http://www.acnet.ge/virol.htm
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| | How the Cholera Bacterium Got Its Virulence |
| | Yet in the series of experiments reported in Science, Mekalanos and Waldron show that the CTX phage does move from a donor bacterium (Vibrio cholera 01) to a nonvirulent recipient bacterium, bringing with it all of its genes. | | | Two Harvard Medical School scientists have found a partial answer to the puzzle. | | | You have to bring something to the party--TCP pilus--but I'll bring the band and we'll have a dance,' " says Mekalanos. |
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http://www.hms.harvard.edu/news/releases/696cholera.html
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| | Tulane T4-like Genome Website |
| | Tulane and New Orleans are coming back to life and so is the phage website. | | | Please report any problems with this site to Jim Nolan | | | Please provide your input for improvements via email or use the Phage forum. |
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http://phage.bioc.tulane.edu
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| | The Guide to Phage Genomics: Home |
| | If no (unlikely with phage genomes), then proceed with conventional library construction | | | The Guide to Phage Genomics: Isolation, Purification, Cloning, Sequencing, Assembling, Annotating and Analyzing Phage Genomes | | | Pull the phage band and dialyze against a buffer |
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http://www.sci.sdsu.edu/PHAGE/guide.html
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| | Bacteriophage Index |
| | P021 - basic supplies and equipment E-broth prob OK reuse plastic plates. | | | http://www.phage.org/ - injects phage DNA I can link to th gif. | | | B022 - Make E-Broth from ground beef on the kitchen stove - a meat broth medium. |
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http://www.disknet.com/indiana_biolab/p.htm
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