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Topic: Paracetamol



  
 Paracetamol - Wikipedia, the free encyclopedia
Paracetamol (INN) (IPA: [pærəˈsitəmɒl, -moʊl, -ˈsɛtə-]) or acetaminophen (USAN) is a common analgesic and antipyretic drug that is used for the relief of fever, headaches, and other minor aches and pains.
Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: analysis of instances of therapeutic misadventure.
When coadministered with amitriptyline 50 mg twice a day, the combination is as effective as paracetamol with codeine, but does not lose effectiveness as an analgesic over time, as does chronic administration of narcotics.
http://en.wikipedia.org/wiki/Paracetamol   (3438 words)

  
 Paracetamol (Vol73)
Paracetamol did not promote urinary bladder carcinogenesis in rats and reduced the incidence of intestinal tumours in a two-stage model of intestinal carcinogenesis in rats.
In the previous monograph on paracetamol, a positive association with cancer of the ureter (but not of other sites in the urinary tract) was observed in an Australian case—control study.
There is inadequate evidence in humans for the carcinogenicity of paracetamol.
http://monographs.iarc.fr/htdocs/monographs/vol73/73-15.html   (876 words)

  
 Antidotes for Poisoning by Paracetamol
There was a resurgence of interest in paracetamol when it was found to be the major metabolite of acetanilide and phenacetin (Brodie & Axelrod, 1948a,b) and it was commonly assumed to be responsible for the therapeutic effects of both of these drugs.
Initially, the reactive metabolite of paracetamol was believed to result from oxidation of the drug to N-hydroxy-paracetamol followed by dehydration to NAPQI (Hinson et al., 1980; Holme et al., 1982).
1.8.9 Paracetamol poisoning in pregnancy Limited information is available concerning the effects of an overdose of paracetamol at different times during the course of pregnancy but serious problems for mother and child seem to be uncommon (MacElhatton et al., 1990).
http://www.inchem.org/documents/antidote/antidote/ant03.htm   (16058 words)

  
 Medicines - Paracetamol
Paracetamol can be taken to relieve mild to moderate pain due to things such as headache, muscle and joint pain, backache and period pains.
Your doctor can also prescribe paracetamol either on its own or in a combination medicine containing another painkiller such as dihydrocodeine or codeine.
Paracetamol is often contained in branded pain relieving products (see list below) and cough and cold remedies.
http://www.bupa.co.uk/health_information/html/medicine/paracetamol.html   (777 words)

  
 Panadol
Paracetamol can be used to relieve mild to moderate pain associated with conditions such as headaches, migraine, toothache, teething, colds and flu.
As paracetamol reduces the production of these nerve sensitising prostaglandins it is thought it may increase our pain threshold, so that although the injury remains, we can feel it less.
One of their actions is to sensitise nerve endings, so that when the injury is stimulated it causes pain (presumably to prevent us from causing further harm to the area).
http://www.netdoctor.co.uk/medicines/100003607.html   (952 words)

  
 Health Report - 4/10/99: Painkillers
But for pain relief, you also have the choice of paracetamol, sightly less effective but easier on your stomach, and ibuprofen, sold here as nurofen or actiprofen, for example.
The patients had common complaints like a sore back or a cold, and were given either aspirin, paracetamol of ibuprofen at random.
Reference: Nicholas Moore et al, The PAIN study: paracetamol, aspirin and ibuprofen new tolerability study.
http://www.abc.net.au/rn/talks/8.30/helthrpt/stories/s57298.htm   (1117 words)

  
 Comparative effect of paracetamol, NSAIDs or their combination in postoperative pain management: a qualitative review ...
The efficacy of ketoprofen and paracetamol (acetaminophen) in postoperative pain after third molar surgery.
and orthopaedic surgery, the efficacies of NSAIDs and paracetamol
Comparative assessment of fenoprofen and paracetamol given in combination for pain after surgery.
http://bja.oxfordjournals.org/cgi/content/full/88/2/199   (6073 words)

  
 Paracetamol
Because paracetamol is a potent drug that is available without prescription, it is often used in suicide attempts, and in this respect it is potentially more dangerous than other over-the-counter drugs such as aspirin.
A new formulation of paracetamol is now being marketed in the UK which incorporates methianine, such that the drug carries its own antidote with it!
The reasons for this poisoning are to do with the process by which paracetamol is eliminated from the body.
http://www.ch.ic.ac.uk/rzepa/mim/drugs/html/paracet_text.htm   (389 words)

  
 BBC News HEALTH Paracetamol linked to asthma
A study suggests that people who take paracetamol every week are almost 80% more likely to have asthma than those who never take the painkiller.
The authors warn that their findings should not encourage asthmatics to switch from paracetamol to aspirin or NSAIDS, as this could be dangerous.
Regular use of the painkiller paracetamol may worsen the symptoms of asthma, say scientists.
http://news.bbc.co.uk/hi/english/health/newsid_683000/683882.stm   (469 words)

  
 PharmWeb - Paracetamol Information Centre
Guidelines for the management of acute paracetamol overdosage
Patients with heart disease must use the right pain reliever
Legislation restricting pack sizes of pain relievers has been successful in reducing overdoses
http://www.pharmweb.net/pwmirror/pwy/paracetamol/pharmwebpic.html   (217 words)

  
 Paracetamol - Family factsheets - GOSH and ICH
Paracetamol is one of the most widely-used medicines in both children and adults and when used according to instructions is very safe.
It is often given following an operation or removal of a dressing so that your child feels less pain and discomfort.
Home > Patients and families > Factsheets > Paracetamol
http://www.gosh.nhs.uk/factsheets/families/F000268   (596 words)

  
 Paracetamol Information Centre - Information for Journalists Reporting on Paracetamol Overdoses or on Inquests ...
Nearly all paracetamol overdoses are taken knowingly, although in some of these cases the expectation was not to die but to go unconscious and then recover, in other words the deliberate attention seeking overdose (2).
Many people believe a paracetamol overdose will cause drowsiness or unconsciousness.
This is the case with many medicines used in overdose, but not with paracetamol.
http://www.pharmweb.net/pwmirror/pwy/paracetamol/pharmwebpicjournalist.html   (724 words)

  
 BBC NEWS Health Paracetamol pregnancy warning
While having a wheezing child is no guarantee of that child becoming asthmatic, it is a risk factor for asthma.
Pregnant women who frequently use painkillers such as paracetamol could increase the chance of a child suffering from wheezing.
Links to more Health stories are at the foot of the page.
http://news.bbc.co.uk/1/hi/health/2369677.stm   (398 words)

  
 Anadin - Products - Anadin Extra
For when you need strong pain relief, Anadin Extra tablets are easy to swallow and have a powerful combination of pain relieving ingredients that work fast.
Each tablet contains 200mg of Paracetamol, 300mg of Aspirin and 45mg of Caffeine.
http://www.anadin.co.uk/products/anadin-extra.html   (234 words)

  
 Paracetamol - Patient UK
For example, if a child is taking antibiotics for an ear infection, keep giving paracetamol as well until the pain and fever ease.
As pain and fever are common, no home should be without some paracetamol, particularly homes with children.
It is usually safe to take paracetamol with other medication.
http://www.patient.co.uk/showdoc.asp?doc=23068798   (379 words)

  
 Treatments: Paracetamol - WrongDiagnosis.com
Count: Paracetamol is listed as a: treatment for 8 conditions; alternative treatment for 8 conditions; preventive treatment for 0 conditions; research treatment for 0 conditions.
Paracetamol as a treatment: The following list of conditions have 'Paracetamol' or similar listed as a treatment in our database:
By using this site you agree to our Terms of Use.
http://www.wrongdiagnosis.com/treat/paracetamol.htm   (132 words)

  
 Paracetamol
Documentation on dangers of using Ibuprofne, tylenol, etc in illness
This is not very helpful when fever is a useful response to infection with a virus or bacterium and runs contrary to the body’s natural attempts to throw out toxins and right itself.
Standard medical advice is to suppress all fevers with Calpol (paracetamol) or Ibuprofen.
http://www.whale.to/drugs/paracetamol1.html   (500 words)

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