Oligosaccharide - Medicow
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Topic: Oligosaccharide



  
 Title of Invention: Methods and products for the sy nthesis of oligosaccharide structures on glycoproteins, ...
This method comprises contacting an oligosaccharide or polysaccharide precursor with a fused protein.
This diversity is not random but rather consists of specific sets of oligosaccharide structures that exhibit precise tissue-specific and developmental expression patterns.
a glycoprotein or glycolipid), soluble oligosaccharide or polysaccharide, or a particular enzymatic activity (vide infra);
http://www.nal.usda.gov/bic/Biotech_Patents/1994patents/05324663.html   (16967 words)

  
 Degradation of Misfolded Endoplasmic Reticulum Glycoproteins in Saccharomyces cerevisiae Is Determined by a Specific ...
Degradation of Misfolded Endoplasmic Reticulum Glycoproteins in Saccharomyces cerevisiae Is Determined by a Specific Oligosaccharide Structure -- Jakob et al.
Degradation of Misfolded Endoplasmic Reticulum Glycoproteins in Saccharomyces cerevisiae Is Determined by a Specific Oligosaccharide Structure
This oligosaccharide structure might be recognized by a lectin,
http://www.jcb.org/cgi/content/full/142/5/1223   (5207 words)

  
 Protein Glycosylation and Diseases: Blood and Urinary Oligosaccharides as Markers for Diagnosis and Therapeutic ...
Varki A. Biological roles of oligosaccharides: all of the theories are correct.
During pregnancy, AFP is also subjected to variations in the oligosaccharide
the interaction of LCA with such oligosaccharide structures,
http://www.clinchem.org/cgi/content/full/46/6/795   (4443 words)

  
 Large-scale isolation of dolichol-linked oligosaccharides with homogeneous oligosaccharide structures: determination of ...
The structure and assembly pathway for dolichol-linked oligosaccharides.
The structure of the major oligosaccharide species for each analysis is depicted.
OST assay was determined by HPLC analysis (Figure 4B).
http://glycob.oxfordjournals.org/cgi/content/full/11/4/321   (6538 words)

  
 Phosphorylase recognition and phosphorolysis of its oligosaccharide substrate: answers to a long outstanding question
The mechanisms of control by phosphorylation and by allosteric effectors are also understood from crystallographic studies on phosphorylated and unphosphorylated forms of the mammalian phosphorylase (Barford and Johnson, 1989; Barford et al., 1991; Sprang et al., 1991; Johnson, 1992).
It was therefore of interest to observe an oligosaccharide substrate bound across the phosphorylase catalytic site and to assess the significance of any conformational change for catalysis.
The mutant Tyr613Phe showed only slightly changed kinetic parameters, a result that can be rationalized from the structure since phenylalanine at position 613 could perform similar stacking interactions with the sugars in sub-sites +3 and +4.
http://www.nature.com/emboj/journal/v18/n17/full/7591874a.html   (9154 words)

  
 Is there any physiological role for gonadotrophin oligosaccharide heterogeneity in humans?: II. A biochemical point of ...
Is there any physiological role for gonadotrophin oligosaccharide heterogeneity in humans?: II.
the consequences of nuances of oligosaccharide structure on
Qasba, P.K., Balaji, P.V., and Rao, V.S.R. (1997) Conformational analysis of asn-linked oligosaccharides – implications in biological processes.
http://humrep.oxfordjournals.org/cgi/content/full/16/5/825   (3586 words)

  
 Identification and localization of glycine in the inner core lipopolysaccharide of Neisseria meningitidis -- Cox et al. ...
H-HMBC NMR spectra of the core oligosaccharide from N.
The core oligosaccharide from L3 galE was chosen for NMR studies
we examined the core oligosaccharide of a clinical isolate NGH15,
http://content.febsjournal.org/cgi/content/full/269/17/4169   (2875 words)

  
 A Novel Carbohydrate-deficient Glycoprotein Syndrome Characterized by a Deficiency in Glucosylation of the ...
H]mannose for 1 h; dolichol-linked oligosaccharides were isolated and the oligosaccharide portion analyzed by HPLC.
Aebi (1996) Isolation of the ALG6 locus of Saccharomyces cerevisiae required for glucosylation in the N-linked glycosylation pathway.
oligosaccharide does only affect the N-linked glycosylation process
http://www.jci.org/cgi/content/full/102/4/647   (3305 words)

  
 Glycosylation Provides Both Stimulatory and Inhibitory Effects on Cell Surface and Soluble CD44 Binding to Hyaluronan ...
changes in oligosaccharide structure for affinity analysis by
To examine the role of the N-linked oligosaccharides, we treated
Our working hypothesis is that the structural heterogeneity of CD44 isoforms is responsible not only for determining the ligand
http://www.jcb.org/cgi/content/full/140/2/431   (8037 words)

  
 MPDU1 mutations underlie a novel human congenital disorder of glycosylation, designated type If -- Schenk et al. 108 ...
Varki, A. Biological roles of oligosaccharides: all of the theories are correct.
We concluded that the biosynthesis of the LLO was affected in
Preparations of oligosaccharides derived from patient S and
http://www.jci.org/cgi/content/full/108/11/1687   (4553 words)

  
 Oligosaccharide Side Chains on Human Secretory IgA Serve as Receptors for Ricin -- Mantis et al. 172 (11): 6838 -- The ...
Data are means ± SE of a single representative experiment performed in triplicate.
Data are means of a single representative experiment performed in duplicate.
Intravascular and mucosal immunoglobulin A: two separate but related systems of immune defense?.
http://www.jimmunol.org/cgi/content/full/172/11/6838   (4971 words)

  
 Oligosaccharide-based Information in Endoplasmic Reticulum Quality Control and Other Biological Systems -- Lehrman 276 ...
The purpose of this minireview is to explore the roles of oligosaccharides as carriers of intra- and intercellular information
with emphasis on the relationships between oligosaccharide metabolism,
LLO pool, it still corresponded to essentially all of the transferred
http://www.jbc.org/cgi/content/full/276/12/8623   (3557 words)

  
 Identification of the ZPC Oligosaccharide Ligand Involved in Sperm Binding and the Glycan Structures of Xenopus laevis ...
The mass analysis for the VE N-linked oligosaccharides utilized
the migration patterns of the VE oligosaccharides resulting
analysis of the N-linked VE oligosaccharides also provided evidence
http://www.biolreprod.org/cgi/content/full/69/6/1822   (4988 words)

  
 Review Articles - McGill Journal of Medicine
To study N-linked oligosaccharide structures on the HIV gp120, Mizouchi et al.
THE USE OF OLIGOSACCHARIDE PROCESSING INHIBITORS TO Previous studies have relied on utilizing glycobiology tools to better understand the mechanism of HIV infectivity and the source of its immunogenicity.
Inhibitors of oligosaccharide processing can also be used to study the steps in the processing of envelope glycoproteins in cells.
http://www.medicine.mcgill.ca/mjm/issues/v07n02/rev_articles/rev_articles.htm   (10091 words)

  
 The Epoch Times Oligosaccharide and Health
This is because the typical oligosaccharide is resistant to digestion in the small intestine so it flows directly into the large intestine where the growth of beneficial probiotic bacteria is stimulated, and the flora of bacteria in the large intestine is improved.
Various kinds of functional oligosaccharides such as starch-related, sucrose-related, and lactose-related oligosaccharides have been developed and widely used in the processing of food, beverages and confections.
According to medical research, oligosaccharide such as fructo-oligosaccharide has similar functions as water-soluble dietary fiber, which could decrease gastrointestinal transit time and improve moderate constipation and diarrhea.
http://english.epochtimes.com/news/5-5-19/28900.html   (326 words)

  
 oligosaccharide on Encyclopedia.com
Sialylation levels influence oligosaccharide quantitation: analyzing response variability using high-pH anion-exchange chromatography and pulsed amperometric detection.
Anika Therapeutics Reports Inhibition of Cancer Tumor Metastasis by Hyaluronic Acid Oligosaccharides in Preclinical Studies.
Sanofi-Synthelabo to Acquire All Interests in ARIXTRA(R), IDRAPARINUX and Other Oligosaccharides From Organon.
http://www.encyclopedia.com/html/X/X-oligosac.asp   (166 words)

  
 The Type I Collagen pro[IMAGE]1(I) COOH-terminal Propeptide N-Linked Oligosaccharide -- Lamand and Bateman 270 (30): ...
Conservation of this motif among the fibrillar collagens has led to the proposal that the oligosaccharide has structural or functional importance, but a role in collagen biosynthesis has not been unambiguously defined.
It seemed possible that the high-mannose oligosaccharide was interacting with a cell surface or pericellular matrix component and that loss of this interaction may have allowed mutant chains to be more readily released into the medium.
This pathway is the major route of uptake and subsequent degradation of circulating C-propeptide.
http://www.jbc.org/cgi/content/full/270/30/17858   (6238 words)

  
 Fluorescent neoglycolipids: Improved probes for oligosaccharide ligand discovery -- Stoll et al. 267 (6): 1795 -- FEBS ...
Stoll, M.S., Mizuochi, T., Childs, R.A. and Feizi, T. (1988) Improved procedure for the construction of neoglycolipids having antigenic and lectin-binding activities from reducing oligosaccharides.
This work is supported by the UK Medical Research Council and
of the lipid moieties, the oligosaccharides are presented in
http://content.febsjournal.org/cgi/content/full/267/6/1795   (4155 words)

  
 Release of polymannose oligosaccharides from vesicular stomatitis virus G protein during endoplasmic ...
-D-mannosidase provides a glucosidase-independent pathway for the formation of complex N-linked oligosaccharides of glycoproteins.
Elbein, A.D. (1991) Glycosidase inhibitors: inhibitors of N-linked oligosaccharide processing.
Spiro, M.J. and Spiro, R.G. (2000) Use of recombinant endomannosidase for evaluation of the processing of N-linked oligosaccharides of glycoproteins and their oligosaccharide-lipid precursors.
http://glycob.oxfordjournals.org/cgi/content/full/11/10/803   (5523 words)

  
 Fluorophore Assisted Carbohydrate Electrophoresis (FACE) as a Quantitative Oligosaccharide Profiling Method
Strengths and weaknesses of FACE analysis for quantitative oligosaccharide analysis will be discussed.
A FACE oligosaccharide profiling method was developed and validated to measure the efficiency of this oligosaccharide modification process.
Fluorescently labelled oligosaccharides are then separated by polyacrylamide gel electrophoresis and visualized by exposure to UV light.
http://www.abrf.org/Other/ABRFMeetings/ABRF98prog/t004.html   (187 words)

  
 Pet food brewers yeasts mos mannan oligosaccharide treats
One mode of action for mannan-based oligosaccharides involves interference with colonization of intestinal pathogens.
Pet food brewers yeasts mos mannan oligosaccharide treats
Contents: Pet food manufacturers ingredients, petfood biscuit and treat ingredients for dogs cats and rodents,
http://www.ultrateck.net/petfood/yeasts.html   (3642 words)

  
 Gas production in humans ingesting a soybean flour derived from beans naturally low in oligosaccharides -- Suarez et ...
The small intestine of humans (and animals) does
The soluble oligosaccharides raffinose and stachyose are present
A comparative study of flatus production in relation to the oligosaccharide content of some legumes.
http://www.ajcn.org/cgi/content/full/69/1/135   (2636 words)

  
 MENINGOCOCCAL OLIGOSACCHARIDE VACCINE - INJECTION side effects, medical uses, and drug interactions.
MENINGOCOCCAL OLIGOSACCHARIDE VACCINE - INJECTION side effects, medical uses, and drug interactions.
MedicineNet Home > Medications A-Z List > meningococcal oligosaccharide vaccine
Read 6 more meningococcal oligosaccharide vaccine related articles...
http://www.medicinenet.com/meningococcal_oligosaccharide_vaccine/article.htm   (439 words)

  
 Investor Relation @ AsiaOne - Pine Agritech
Soy oligosaccharide syrup is made up of the saccharides contained in soybean, and is a food material that enhances the growth of bifidobacteria in the intestines which are essential for intestinal health.
Soy oligosaccharide syrup, classified as prebiotics, is non-digestible and when ingested, will selectively stimulate favourable bifidobacteria growth in the intestines and colon, thereby improving digestion.
Our soy oligosaccharide syrup is a health-care food product approved by the Ministry of Health of the PRC and has been registered with the
http://ir.asiaone.com/pineagritech   (537 words)

  
 Fibrinogen Niigata With Impaired Fibrin Assembly: An Inherited Dysfibrinogen With a Bbeta Asn-160 to Ser Substitution ...
Fibrinogen was purified from normal and patient citrated plasma, and human
The location of extra oligosaccharides in some abnormal fibrinogens suggests possible explanations of their effect on fibrin
Niigata may perturb the lateral association of protofibrils and
http://www.bloodjournal.org/cgi/content/full/94/11/3806   (4679 words)

  
 Encyclopedia topic: Carbohydrate
The distinction between the two is based upon the number of monosaccharide units present in the chain.
Oligosaccharides typically contain between 3 and 9 monosaccharide units and polysaccharides contain greater than 10 monosaccharide units.
Definitions of how large a carbohydrate must be to fall into each category vary however.
http://www.absoluteastronomy.com/encyclopedia/c/ca/carbohydrate.htm   (914 words)

  
 Energy Citations Database (ECD) - Energy and Energy-Related Bibliographic Citations
Oligosaccharide processing in the expression of human plasminogen cDNA by lepidopteran insect (Spodoptera frugiperda) cells
Availability information may be found in the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or via the "Full-text Availability" link.
Energy Citations Database (ECD) Document #5394506 - Oligosaccharide processing in the expression of human plasminogen cDNA by lepidopteran insect (Spodoptera frugiperda) cells
http://www.osti.gov/energycitations/product.biblio.jsp?osti_id=5394506   (120 words)

  
 ExPASy - History list
The program can be used for free or derivatized oligosaccharides and for glycopeptides.
GlycoMod: Possible oligosaccharide structures suggested by GlycoMod are linked to the GlycoSuiteDB database of glycan structures, if they are reported in this database.
GlycoMod is a tool that can predict the possible oligosaccharide structures occurring on proteins from their experimentally determined masses.
http://www.expasy.org/history.html   (12395 words)

  
 Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries
Specific oligosaccharide structures used in signal transduction processes
Tools for "On-Bead" Monitoring and Analysis in Solid-Phase Oligosaccharide Synthesis
With chapters written by eminent contributing authors, the material explores different synthetic strategies, glycosylation protocols, the use of solid supports versus soluble polymeric supports, and "on-resin" analytical methods.
http://www.chipsbooks.com/sololigo.htm   (304 words)

  
 Oligosaccharide - Wikipedia, the free encyclopedia
An oligosaccharide is a saccharide polymer containing a small number (typically three to six) of component sugars, also known as simple sugars.
A and B blood types have two different oligosaccharide glycolipids embedded in the cell membranes of the red blood cells, AB-type blood has both, while O blood type has none.
They are generally found either O- or N-linked to compatible amino acid side chains in proteins or to lipid moieties.
http://en.wikipedia.org/wiki/Oligosaccharide   (141 words)

  
 Bone Marrow Transplants for Oligosaccharide Storage Diseases
Nonetheless, it is an option that may be worth exploring.
For other Oligosaccharide Disorders the track record is sparse and not yet proven viable.
Alpha Mannosidosis and Fucosidosis patients have seen promising results with the few transplants performed thus far.
http://www.mannosidosis.org/bmtinfo.htm   (276 words)

  
 AllRefer.com - oligosaccharide (Biochemistry) - Encyclopedia
You are here : AllRefer.com > Reference > Encyclopedia > Biochemistry > oligosaccharide
http://reference.allrefer.com/encyclopedia/X/X-oligosac.html   (92 words)

  
 chitosan, and chitosan oligosaccharide, collagen
The World Wide source for Chitosan, and Chitosan Oligosaccharide
First Quality Bulk Chitin / Chitosan, and Chitosan Oligosaccharide
http://dalwoo.com/chitosan   (144 words)

  
 University of Maryland Division of Pediatric Genetics Information Guide
Cytogenetics: routine banding and fluorescence in situ hybridization analysis of amniotic fluid, chorionic villi, peripheral blood, bone marrow, products of conception and solid tumors
Quantitative amino acid and organic acid analysis, mucopolysaccharide and oligosaccharide screening, assays for 18 different lysosomal enzymes, carnitine, biotinidase, enzymes and metabolites involved in galactosemia; Tay-Sachs screening routinely offered
http://www.marylandgenetics.org   (420 words)

  
 FACE(R)
Purchase of Glyko FACE Kits or components grants a sublicense to use FACE Analysis under Glyko's patents.
GK60020 Oligosaccharide Profiling Gel (10-pack), GK50300 N-Linked Sequencing Enzyme Set and GK50306 N-Linked Oligosaccharide Sequencing Standards and Control
For Determining the sequence of sugars in an isolated N-linked oligosaccharide.
http://www.prozyme.com/glyko/face.html   (529 words)

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