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| | Title of Invention: Methods and products for the sy nthesis of oligosaccharide structures on glycoproteins, ... |
 | | This method comprises contacting an oligosaccharide or polysaccharide precursor with a fused protein. |  | | This diversity is not random but rather consists of specific sets of oligosaccharide structures that exhibit precise tissue-specific and developmental expression patterns. |  | | a glycoprotein or glycolipid), soluble oligosaccharide or polysaccharide, or a particular enzymatic activity (vide infra); |
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http://www.nal.usda.gov/bic/Biotech_Patents/1994patents/05324663.html
(16967 words)
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| | Phosphorylase recognition and phosphorolysis of its oligosaccharide substrate: answers to a long outstanding question |
 | | The mechanisms of control by phosphorylation and by allosteric effectors are also understood from crystallographic studies on phosphorylated and unphosphorylated forms of the mammalian phosphorylase (Barford and Johnson, 1989; Barford et al., 1991; Sprang et al., 1991; Johnson, 1992). |  | | It was therefore of interest to observe an oligosaccharide substrate bound across the phosphorylase catalytic site and to assess the significance of any conformational change for catalysis. |  | | The mutant Tyr613Phe showed only slightly changed kinetic parameters, a result that can be rationalized from the structure since phenylalanine at position 613 could perform similar stacking interactions with the sugars in sub-sites +3 and +4. |
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http://www.nature.com/emboj/journal/v18/n17/full/7591874a.html
(9154 words)
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| | Review Articles - McGill Journal of Medicine |
 | | To study N-linked oligosaccharide structures on the HIV gp120, Mizouchi et al. |  | | THE USE OF OLIGOSACCHARIDE PROCESSING INHIBITORS TO Previous studies have relied on utilizing glycobiology tools to better understand the mechanism of HIV infectivity and the source of its immunogenicity. |  | | Inhibitors of oligosaccharide processing can also be used to study the steps in the processing of envelope glycoproteins in cells. |
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http://www.medicine.mcgill.ca/mjm/issues/v07n02/rev_articles/rev_articles.htm
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| | The Epoch Times Oligosaccharide and Health |
 | | This is because the typical oligosaccharide is resistant to digestion in the small intestine so it flows directly into the large intestine where the growth of beneficial probiotic bacteria is stimulated, and the flora of bacteria in the large intestine is improved. |  | | Various kinds of functional oligosaccharides such as starch-related, sucrose-related, and lactose-related oligosaccharides have been developed and widely used in the processing of food, beverages and confections. |  | | According to medical research, oligosaccharide such as fructo-oligosaccharide has similar functions as water-soluble dietary fiber, which could decrease gastrointestinal transit time and improve moderate constipation and diarrhea. |
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http://english.epochtimes.com/news/5-5-19/28900.html
(326 words)
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| | oligosaccharide on Encyclopedia.com |
 | | Sialylation levels influence oligosaccharide quantitation: analyzing response variability using high-pH anion-exchange chromatography and pulsed amperometric detection. |  | | Anika Therapeutics Reports Inhibition of Cancer Tumor Metastasis by Hyaluronic Acid Oligosaccharides in Preclinical Studies. |  | | Sanofi-Synthelabo to Acquire All Interests in ARIXTRA(R), IDRAPARINUX and Other Oligosaccharides From Organon. |
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http://www.encyclopedia.com/html/X/X-oligosac.asp
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| | The Type I Collagen pro[IMAGE]1(I) COOH-terminal Propeptide N-Linked Oligosaccharide -- Lamand and Bateman 270 (30): ... |
 | | Conservation of this motif among the fibrillar collagens has led to the proposal that the oligosaccharide has structural or functional importance, but a role in collagen biosynthesis has not been unambiguously defined. |  | | It seemed possible that the high-mannose oligosaccharide was interacting with a cell surface or pericellular matrix component and that loss of this interaction may have allowed mutant chains to be more readily released into the medium. |  | | This pathway is the major route of uptake and subsequent degradation of circulating C-propeptide. |
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http://www.jbc.org/cgi/content/full/270/30/17858
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| | Release of polymannose oligosaccharides from vesicular stomatitis virus G protein during endoplasmic ... |
 | | -D-mannosidase provides a glucosidase-independent pathway for the formation of complex N-linked oligosaccharides of glycoproteins. |  | | Elbein, A.D. (1991) Glycosidase inhibitors: inhibitors of N-linked oligosaccharide processing. |  | | Spiro, M.J. and Spiro, R.G. (2000) Use of recombinant endomannosidase for evaluation of the processing of N-linked oligosaccharides of glycoproteins and their oligosaccharide-lipid precursors. |
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http://glycob.oxfordjournals.org/cgi/content/full/11/10/803
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| | Fluorophore Assisted Carbohydrate Electrophoresis (FACE) as a Quantitative Oligosaccharide Profiling Method |
 | | Strengths and weaknesses of FACE analysis for quantitative oligosaccharide analysis will be discussed. |  | | A FACE oligosaccharide profiling method was developed and validated to measure the efficiency of this oligosaccharide modification process. |  | | Fluorescently labelled oligosaccharides are then separated by polyacrylamide gel electrophoresis and visualized by exposure to UV light. |
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http://www.abrf.org/Other/ABRFMeetings/ABRF98prog/t004.html
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| | Pet food brewers yeasts mos mannan oligosaccharide treats |
 | | One mode of action for mannan-based oligosaccharides involves interference with colonization of intestinal pathogens. |  | | Pet food brewers yeasts mos mannan oligosaccharide treats |  | | Contents: Pet food manufacturers ingredients, petfood biscuit and treat ingredients for dogs cats and rodents, |
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http://www.ultrateck.net/petfood/yeasts.html
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| | Investor Relation @ AsiaOne - Pine Agritech |
 | | Soy oligosaccharide syrup is made up of the saccharides contained in soybean, and is a food material that enhances the growth of bifidobacteria in the intestines which are essential for intestinal health. |  | | Soy oligosaccharide syrup, classified as prebiotics, is non-digestible and when ingested, will selectively stimulate favourable bifidobacteria growth in the intestines and colon, thereby improving digestion. |  | | Our soy oligosaccharide syrup is a health-care food product approved by the Ministry of Health of the PRC and has been registered with the |
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http://ir.asiaone.com/pineagritech
(537 words)
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| | Encyclopedia topic: Carbohydrate |
 | | The distinction between the two is based upon the number of monosaccharide units present in the chain. |  | | Oligosaccharides typically contain between 3 and 9 monosaccharide units and polysaccharides contain greater than 10 monosaccharide units. |  | | Definitions of how large a carbohydrate must be to fall into each category vary however. |
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http://www.absoluteastronomy.com/encyclopedia/c/ca/carbohydrate.htm
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| | Energy Citations Database (ECD) - Energy and Energy-Related Bibliographic Citations |
 | | Oligosaccharide processing in the expression of human plasminogen cDNA by lepidopteran insect (Spodoptera frugiperda) cells |  | | Availability information may be found in the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or via the "Full-text Availability" link. |  | | Energy Citations Database (ECD) Document #5394506 - Oligosaccharide processing in the expression of human plasminogen cDNA by lepidopteran insect (Spodoptera frugiperda) cells |
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http://www.osti.gov/energycitations/product.biblio.jsp?osti_id=5394506
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| | ExPASy - History list |
 | | The program can be used for free or derivatized oligosaccharides and for glycopeptides. |  | | GlycoMod: Possible oligosaccharide structures suggested by GlycoMod are linked to the GlycoSuiteDB database of glycan structures, if they are reported in this database. |  | | GlycoMod is a tool that can predict the possible oligosaccharide structures occurring on proteins from their experimentally determined masses. |
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http://www.expasy.org/history.html
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| | Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries |
 | | Specific oligosaccharide structures used in signal transduction processes |  | | Tools for "On-Bead" Monitoring and Analysis in Solid-Phase Oligosaccharide Synthesis |  | | With chapters written by eminent contributing authors, the material explores different synthetic strategies, glycosylation protocols, the use of solid supports versus soluble polymeric supports, and "on-resin" analytical methods. |
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http://www.chipsbooks.com/sololigo.htm
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| | Oligosaccharide - Wikipedia, the free encyclopedia |
 | | An oligosaccharide is a saccharide polymer containing a small number (typically three to six) of component sugars, also known as simple sugars. |  | | A and B blood types have two different oligosaccharide glycolipids embedded in the cell membranes of the red blood cells, AB-type blood has both, while O blood type has none. |  | | They are generally found either O- or N-linked to compatible amino acid side chains in proteins or to lipid moieties. |
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http://en.wikipedia.org/wiki/Oligosaccharide
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| | Bone Marrow Transplants for Oligosaccharide Storage Diseases |
 | | Nonetheless, it is an option that may be worth exploring. |  | | For other Oligosaccharide Disorders the track record is sparse and not yet proven viable. |  | | Alpha Mannosidosis and Fucosidosis patients have seen promising results with the few transplants performed thus far. |
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http://www.mannosidosis.org/bmtinfo.htm
(276 words)
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| | University of Maryland Division of Pediatric Genetics Information Guide |
 | | Cytogenetics: routine banding and fluorescence in situ hybridization analysis of amniotic fluid, chorionic villi, peripheral blood, bone marrow, products of conception and solid tumors |  | | Quantitative amino acid and organic acid analysis, mucopolysaccharide and oligosaccharide screening, assays for 18 different lysosomal enzymes, carnitine, biotinidase, enzymes and metabolites involved in galactosemia; Tay-Sachs screening routinely offered |
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http://www.marylandgenetics.org
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| | FACE(R) |
 | | Purchase of Glyko FACE Kits or components grants a sublicense to use FACE Analysis under Glyko's patents. |  | | GK60020 Oligosaccharide Profiling Gel (10-pack), GK50300 N-Linked Sequencing Enzyme Set and GK50306 N-Linked Oligosaccharide Sequencing Standards and Control |  | | For Determining the sequence of sugars in an isolated N-linked oligosaccharide. |
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http://www.prozyme.com/glyko/face.html
(529 words)
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