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 Neutropenia - Wikipedia, the free encyclopedia
There is no ideal therapy for neutropenia, but recombinant G-CSF (granulocyte-colony stimulating factor) can be effective in chemotherapy patients and some other causes.
Severe chronic neutropenia may be present at birth (congenital neutropenia) or may occur at any stage in life (acquired neutropenia).
This is the rarest form of severe chronic neutropenia.
http://en.wikipedia.org/wiki/Neutropenia   (670 words)

  
 Neutropenia
The primary cause of Neutropenia is chemotherapy and various other cancer treatments such as radiation therapy, biotherapy, and bone marrow transplantation.
According to the Awareness of Neutropenia in Chemotherapy Study Group — a group of researchers working to develop risk models to help identify at-risk patients — Neutropenia and its consequences are more common and severe than reported.
The management of Neutropenia includes strategies to avoid infections, detect them early and respond to them promptly and aggressively, as well as therapies to help restore immune system function.
http://www.bymyside.com/neutropenia.html   (900 words)

  
 Advances in the Management of Chemotherapy Induced Neutropenia
Neutropenia is the primary dose-limiting toxicity of myelosuppressive therapy.
Prophylaxis against neutropenia in all patients would not be feasible in terms of resource utilization, as this practice would place a significant financial burden on the medical system due to the use of colony stimulating factors (CSFs) in patients who might not develope neutropenia.
Much emphasis was placed on prevention and early intervention of neutropenia with assessment of patient risk factors and of a proactive approach utilizing growth factors.
http://professional.cancerconsultants.com/current_oncology_2003.aspx?id=79   (3149 words)

  
 About Neutropenia - Neutropenia Support Association Inc.
Severe chronic neutropenia is most frequently encountered as a paediatric problem.
There are several forms of congenital neutropenia varying in the severity of reduction of neutrophil counts and the associated clinical problems.
People can get neutropenia when treated for cancer with chemotherapy drugs.
http://www.neutropenia.ca/about   (1488 words)

  
 Further Evidence that Neulasta™ is The Most Effective Agent for Reducing Febrile Neutropenia
One clinical trial compared the incidence of febrile neutropenia (neutropenia accompanied by a fever) in patients treated with Neulasta™ or Neupogen® while the second clinical trial compared the incidence of febrile neutropenia in patients treated with Neulasta™ or no support therapy for neutropenia.
Patients who are scheduled to undergo cancer therapy may wish to discuss the risks and benefits of Neulasta™ with their physician or the participation in a clinical trial further evaluating Neulasta™.
In the second trial, 19% of patients treated with Neulasta™ experienced febrile neutropenia, compared to 38% of patients treated with no support for neutropenia.
http://www.cancerconsultants.com/syndication/veContent.jsp?ArticleID=suppcare_oct02&clinicid=1&ArticleTypeID=News   (555 words)

  
 THE MERCK MANUAL, Sec. 11, Ch. 135, Leukopenia And Lymphocytopenia
144), or immunosuppressive therapy differs from that of congenital or chronic forms of neutropenia.
It usually corresponds to a period of acute viremia and is related to virus-induced redistribution of neutrophils from the circulating to the marginal pool.
Long-term G-CSF has also been used to prevent neutropenia in other circumstances, including myelodysplasia, HIV and AIDS, and autoimmune disorders.
http://www.merck.com/pubs/mmanual/section11/chapter135/135a.htm   (2424 words)

  
 Congenital and Acquired Neutropenia -- Berliner et al. 2004 (1): 63 -- Hematology
Autoimmune neutropenia: clinical and laboratory studies in 143 patients.
Diagnosis and clinical course of autoimmune neutropenia in infancy: analysis of 240 cases.
Leukemia in severe congenital neutropenia: defective proteolysis suggests new pathways to malignancy and opportunities for therapy.
http://www.asheducationbook.org/cgi/content/full/2004/1/63   (7327 words)

  
 Neutropenia SIG Newsletter
The project demonstrated that the use of a systematic neutropenia risk assessment tool may help practitioners determine which patients are at increased risk for chemotherapy-induced neutropenia.
Charts were reviewed for 35 patients who had been assessed using the neutropenia risk assessment tool and outcomes were compared to those of 50 historical cases who received care prior to the implementation of the neutropenia risk assessment tool.
Reflecting on this Web conference, I realized that it has taken time for standards of care to be published regarding the use of CSF in the medical management of neutropenia associated with cancer therapy.
http://onsopcontent.ons.org/Publications/SIGNewsletters/neutro/neutro3.2.html   (4124 words)

  
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Infrequently, cancer patients may also experience neutropenia from other medications or as a consequence of their underlying cancer.
The most common side effect you may experience with Neulasta® is aching in the bones and muscles.
Symptoms persist only while being used and can typically be treated with non-narcotic analgesic medicines.
http://patient.cancerconsultants.com/supportive_treatment.aspx?id=993   (2272 words)

  
 Neutropenia SIG Newsletter
One of the problems identified early in the development of the Neutropenia SIG was the lack of nursing research in the care of patients with neutropenia.
In 2001, the Neutropenia Focus Group felt that an assessment of current practices in the care of patients with neutropenia was an important step for identifying areas of future research.
Four hundred twenty-one people responded (28%); the data were analyzed in March 2003 and presented as a poster session at the ONS 28th Annual Congress in May. Table 1 shows the percentage of respondents who answered positively to various questions in the survey.
http://onsopcontent.ons.org/Publications/SIGNewsletters/neutro/neutro1.2.html   (1417 words)

  
 Neutropenia Support Association Inc.
Increasing the understanding of neutropenia by providing information and support for care givers, patients and their families.
This site has been developed by assembling many articles about Neutropenia and organizing them into different categories to assist you in learning more about this disease.
We maintain an information library to answer questions from patients, their families, and the medical community.
http://www.neutropenia.ca   (410 words)

  
 CancerSymptoms.org
Information provides a way to help patients and families gain control of a disease process that often seems to be invading every part of their life.
Neutropenia can be managed and treated if necessary.
This will help you to understand other people's perspectives and experiences with neutropenia.
http://www.cancersymptoms.org/neutropenia/index.shtml   (178 words)

  
 Severe Chronic Neutropenia - Family factsheets - GOSH and ICH
This leaflet explains Severe Chronic Neutropenia and what to expect when your child comes to Great Ormond Street for treatment.
Most infections occur in the ears, skin or throat and to a lesser extent, the chest.
Severe Chronic Neutropenia - Family factsheets - GOSH and ICH
http://www.gosh.nhs.uk/factsheets/families/F010206   (1337 words)

  
 Inherited Neutrophil Disorders: Molecular Basis and New Therapies -- Dinauer et al. 2000 (1): 303 -- Hematology
Myelodysplasia and acute myeloid leukemia in patients with congenital neutropenia receiving G-CSF therapy.
Welte K, Boxer LA. Severe chronic neutropenia: pathophysiology and therapy.
of severe congenital neutropenia, but the relationship between
http://www.asheducationbook.org/cgi/content/full/2000/1/303   (7146 words)

  
 Congenital Autoimmune Neutropenia in Two Premature Neonates -- Calhoun et al. 108 (1): 181 -- Pediatrics
than severe chronic neutropenia (incidence 1:1 000 000).
associated with IVIG therapy, the neutropenia developed rapidly
and the neonate was enrolled in the Severe Chronic Neutropenia
http://pediatrics.aappublications.org/cgi/content/full/108/1/181   (1962 words)

  
 Neutropenia Interferes With Symptom Management
Prevention of neutropenia with available therapies may improve a range of patient outcomes.
Patients in the intervention group were contacted by a nurse 10 times over the course of 20 weeks for symptom assessment and management.
The researchers conclude that cancer patients who developed neutropenia did not benefit from a clinical intervention to reduce symptom burden; reasons for this are likely to be complex.
http://patient.cancerconsultants.com/news.aspx?id=34820   (430 words)

  
 Imaginis - Neutropenia
According to the Neutropenia Support Association, up to one third of patients who receive chemotherapy become neutropenic.
The association provides assistance to neutropenic patients and their families and also raises money for research and education.
Neutropenia is most common during or after a patient receives chemotherapy to treat cancer.
http://imaginis.com/breasthealth/neutropenia.asp   (1100 words)

  
 Barth Syndrome - X-linked Cardiomyopathy and Neutropenia
However many of these more characteristically have a hypertrophic rather than dilated cardiomyopathy and are not associated with chronic or cyclic neutropenia.
The skeletal muscle also had a number of mostly non-specific histological changes, such as mildly increased fat vacuolization of type I fibers and increased subsarcolemmal spaces without ragged red changes.
However, many other patients with severe neutropenia do not have recurrent infections, possibly because of a chronic, substantial monocytosis.
http://www.hopkinsmedicine.org/cmsl/Barth_Summary.html   (4402 words)

  
 Neutropenia
Your medical professional will check to see if you have neutropenia every time you get a blood test.
If you develop neutropenia during your chemotherapy, your doctor may prescribe NEUPOGEN® to help:
Unlike other physical side effects of chemotherapy, neutropenia often has silent symptoms.
http://www.chemotherapysideeffects.ca/neutropenia.html   (824 words)

  
 Neutropenia definition - Medical Dictionary definitions of popular medical terms
Granulocytopenia can therefore more specifically involve neutropenia (shortage of neutrophils), eosinopenia and/or basopenia.
Our Neutropenia Main Article provides a comprehensive look at the who, what, when and how of Neutropenia
Granulocytopenia or, as it is also called, agranulocytosis results in a syndrome of frequent chronic bacterial infections of the skin, lungs, etc. Although "agranulocytosis" literally means no granulocytes, there may, in fact, be some granulocytes but too few of them, i.e.
http://www.medterms.com/script/main/art.asp?articlekey=4560   (451 words)

  
 Neutropenia AHealthyMe.com
Baehner, Robert L. "Neutropenia." In Conn's Current Therapy, 1996, ed.
"Hematology and Oncology: Leukopenia; Neutropenia." In The Merck Manual of Diagnosis and Therapy.
Recovery from acute neutropenia depends on the severity of the patient's infection and the promptness of treatment.
http://www.ahealthyme.com/topic/topic100587216   (662 words)

  
 Neutropenia
However, patients with even mild forms can develop major problems.
One technical term of which cancer patients should be aware is "Febrile Neutropenia,"
Another approach to treatment of febrile Neutropenia is the use of medicines, which stimulate bone marrow to produce more white blood cells.
http://www.tirgan.com/leucpnia.htm   (325 words)

  
 eMedicine - Neutropenia : Article by John E Godwin, MD, MS
For further information on pancytopenia, refer to Bone Marrow Failure.
Age: Elderly individuals have a higher incidence rate than younger individuals.
Neutropenia is severe, and the treatment is G-CSF.
http://www.emedicine.com/med/topic1640.htm   (3957 words)

  
 Adult Health Advisor 2005.2: Neutropenia
You should speak to your physician or make an appointment to be seen if you have questions or concerns about this information or your medical condition.
New medicines called colony stimulating factors may also be used to stimulate the growth of neutrophils.
In some cases the cause may be the side effect of a drug or exposure to certain poisons.
http://www.med.umich.edu/1libr/aha/aha_neutrope_crs.htm   (462 words)

  
 Neutropenia
If the condition does not clear up by itself, the patient may need drugs or other therapies.
A condition called chronic benign neutropenia of childhood also usually clears up by itself.
Medicine for unrelated medical disorders, other blood cell deficiencies, hereditary diseases, cancers, tuberculosis, vitamin deficiencies, and other conditions can cause neutropenia.
http://www.mayoclinic.org/peds-whitecell-rst/neutropenia.html   (250 words)

  
 Medications which may reduce the neutrophil count (neutropenia).
GlobalRPH does not directly or indirectly practice medicine or provide medical services and therefore assumes no liability whatsoever of any kind for the information and data accessed through the Service or for any diagnosis or treatment made in reliance thereon.
Medications which may reduce the neutrophil count (neutropenia).
PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE.
http://www.globalrph.com/neutropenia.htm   (80 words)

  
 Neutropenia: Patient Information: Arizona Telemedicine Program
Neutropenia is diagnosed by patient history, physical examination for symptoms, and laboratory testing.
Ionizing radiation used in cancer therapy and folic acid deficiency or vitamin B
The primary treatment for neutropenia is to address the underlying cause of the problem.
http://www.telemedicine.arizona.edu/patient_info/benign_disorders/disorders/neutropenia.html   (401 words)

  
 Introduction: Neutropenia - WrongDiagnosis.com
Treatments for Neutropenia: Various information is available about treatments available for Neutropenia, or research treatments for other diseases.
Researching symptoms of Neutropenia: Further information about the symptoms of Neutropenia is available including a list of symptoms of Neutropenia, or alternatively return to research other symptoms in the symptom center.
Causes of Neutropenia: Research more detailed information about the causes of Neutropenia, other possibly hidden causes of Neutropenia, or other general information about Neutropenia.
http://www.wrongdiagnosis.com/n/neutropenia/intro.htm   (160 words)

  
 UpToDate Drug-induced neutropenia and agranulocytosis
(See "Overview of neutropenia" for an approach to the patient with neutropenia).
• Hematopoietic colony-stimulating factors for treatment and prophylaxis of chemotherapy-induced febrile neutropenia
(See "Primary immune neutropenia" and see "Neutropenia associated with infections" and see "Hematopoietic colony-stimulating factors for treatment and prophylaxis of chemotherapy-induced febrile neutropenia").
http://patients.uptodate.com/topic.asp?file=whitecel/4821   (407 words)

  
 Neutropenia
This condition is most severe in patients who receive aggressive treatments.
Resources for Severe Chronic Neutropenia (SCN) - neutropenia.ca
Neutropenia accompanied by monocytopenia and lymphocytopenia is often a more serious disorder than neutropenia alone."
http://www.lymphomation.org/side-effect-neutropenia.htm   (524 words)

  
 Neutropenia Symptoms, Causes, Diagnosis, and Treatment on MedicineNet.com
Neutropenia Symptoms, Causes, Diagnosis, and Treatment on MedicineNet.com
MedicineNet Home > Diseases and Conditions A-Z List > Neutropenia
Diseases causing decreased production of white blood cells include drug toxicity, vitamin deficiencies, and medical diseases such as blood diseases, infections (virus diseases, tuberculosis, typhoid), abnormalities of the bone marrow disorders, or be cyclic (varying in severity week to week, month to month, perhaps related to biorhythms).
http://www.medicinenet.com/neutropenia/article.htm   (441 words)

  
 Perry Scientific - Neutropenia
Neutropenia, the depression of neutrophil counts in blood, is a common side effect of cancer chemotherapy.
Perry Scientific is a leader in the evaluation of new cancer agents using neutropenia models.
This same depression of neutrophil counts or depression of blood cell levels in general, can also occur in patients with leukemia.
http://www.perryscientific.com/neutropenia.html   (285 words)

  
 Neutropenia, Severe Chronic
Severe chronic neutropenia is a rare blood disorder characterized by abnormally low levels of certain white blood cells (neutrophils) in the body (neutropenia).
There are three main forms of the disorder: congenital, idiopathic, and cyclic neutropenia.
Severe chronic neutropenia may be inherited or acquired or may occur for unknown reasons (idiopathic).
http://my.webmd.com/hw/health_guide_atoz/nord857.asp   (468 words)

  
 Neutropenia: chemotherapy risks
Patients who already have neutropenia, or who have previously received chemotherapy or radiation treatment.
While any patient receiving chemotherapy is potentially at risk for developing neutropenia, certain people are at higher risk:
The most common side effects of chemotherapy include neutropenia (a low white blood cell count), anemia (a low red blood cell count), thrombocytopenia (a low blood platelet count), nausea, hair loss, and emotional effects.
http://www.bymyside.com/chemo/chemo_risks.jsp   (439 words)

  
 Neutropenia - MayoClinic.com
Severe neutropenia increases the risk of infection of the lungs, kidneys, blood and skin.
Neutropenia isn't a disease but a sign of an underlying problem.
It may be found incidentally on a blood test done for some other reason.
http://www.mayoclinic.com/health/neutropenia/HQ01112   (209 words)

  
 MedlinePlus Medical Encyclopedia: Neutropenia - infants
The outcome of the baby depends on the underlying cause of the neutropenia.
Of primary importance is to investigate the source or the site of the infection and treat the underlying infectious process that caused the neutropenia.
A simple blood infection or pneumonia usually does not cause long-term side-effects after complete recovery.
http://www.nlm.nih.gov/medlineplus/ency/article/007230.htm   (549 words)

  
 ACCP Site Map
Pegfilgrastim: A New Era in the Management of Chemotherapy-Induced Neutropenia
http://www.accp.com/sitemap.php   (435 words)

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