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Topic: Neuropathic pain


  
 Postgraduate Medicine: Following the clues to neuropathic pain
Anesthesia dolorosa is one of the hallmarks of neuropathic pain.
Neuropathic pain is often puzzling and frustrating for both patients and physicians because it seems to have no cause, responds poorly to standard pain therapies, can last indefinitely and even escalate over time, and often results in severe disability.
Certain medical conditions (table 1) are associated with neuropathic pain, and when a patient with such a condition presents with pain, a neuropathic process should be considered.
http://www.postgradmed.com/issues/1999/11_99/neuropathic.htm   (4097 words)

  
 Understanding Nociceptive and Neuropathic Pain
Neuropathic pain is frequently chronic, and tends to have a less robust response to treatment with opioids, but may respond well to other drugs such as anti-seizure and antidepressant medications.
Visceral pain is the subtype of nociceptive pain that involves the internal organs.
Neuropathic pain is the result of an injury or malfunction in the peripheral or central nervous system.
http://www.helpforpain.com/arch2000dec.htm   (800 words)

  
 Understanding Neuropathic Pain
The hallmarks of neuropathic pain are chronic allodynia and hyperalgesia.
This pain condition is usually neuropathic in nature and accounts for a large number of patients presenting to pain clinics with chronic, non–malignant pain.
In cancer patients, pain associated with tumor compression of neural structures is clinically indistinguishable from non–malignant neuropathic pain.
http://www.spineuniverse.com/displayarticle.php/article1614.html   (4909 words)

  
 THE MERCK MANUAL, Sec. 14, Ch. 167, Pain
Pain that may be ameliorated by manipulating the sympathetic nervous system (ie, sympathetically maintained pain) should be distinguished from pain that is not.
Deafferentation pain due to peripheral nerve damage must be distinguished from other forms of neuropathic pain in which an ongoing, potentially treatable pathologic process affects a peripheral nerve.
For example, a thalamic lesion that causes pain without autonomic or trophic changes and that is unresponsive to manipulation of the sympathetic nervous system is clearly distinct from a lesion that produces reflex sympathetic dystrophy, in which all of these characteristics may be present.
http://www.merck.com/pubs/mmanual/section14/chapter167/167d.htm   (1100 words)

  
 Brain Briefings: Neuropathic Pain
The animal models of neuropathic pain also are helping to determine whether medications used to treat other ailments might work for the treatment of pain.
This is an especially unfortunate fate for the many patients who don't respond to traditional pain treatments.
But now a number of new discoveries, derived from years of animal research, are leading to the development of unique therapies for those with the pain condition.
http://www.sfn.org/content/Publications/BrainBriefings/neuropathic.html   (775 words)

  
 Hospital Practice: Chronic Pain
Chronic pain (or maledynia), unlike normal everyday pain, is a destructive disease with physical, psychological, and behavioral consequences.
Pain signals from peripheral nerves are thus heightened, and the cycle of chronic pain is continued (Figure 4).
The emotional component of pain may be increased, for example, if the new connections channel more of the pain signal to the reticular activating system of the brain.
http://www.hosppract.com/issues/2000/07/brook.htm   (2829 words)

  
 Hospital Practice: Neuropathic Pain
While the standard drugs are ineffective against neuropathic pain, the new drugs have no effect on normal pain sensation.
Indeed, it is estimated that in half of cancer patients whose pain is rated as moderate or greater, the pain is partly or wholly neuropathic.
The reorganization suggests that efforts to explain neuropathic pain on the basis of normal pain processing are at least partly misguided.
http://www.hosppract.com/issues/1998/10/bennett.htm   (5599 words)

  
 Neurontin Significantly Reduces Chronic Neuropathic Pain
DPN is characterised by nerve fibre loss that can result in symptoms ranging from diminished pain and temperature perception, paresthesia (pins and needles) and neuropathic (sharp or burning) pain, to loss of light touch and muscle weakness.
In the majority of patients, the condition is characterised by intense pain that has been described by sufferers as burning, deep aching, tearing and electric shock-like.
A companion study examined the use of Neurontin in patients suffering from post-herpetic neuralgia (PHN), the chronic neuropathic pain condition that can follow shingles (herpes zoster).
http://www.pslgroup.com/dg/D6AC6.htm   (880 words)

  
 Neuropathic Pain or Neuralgia
In nature, pain is suppose to be a response to a noxious stimulus to teach us to not do whatever we did that caused the pain in the first place.
Most pain medications that we think of - tylenol, aspirin, ibuprofen, codeine, morphine, and other narcotics, are tested in models of pain that do not involve damage to the peripheral nervous system itself.
When neurologists think of neuropathic pain, we are refering to pain being caused by the peripheral nerve fibers themselves.
http://www.loftusmd.com/Articles/Pain/overview.html   (467 words)

  
 Postgraduate Medicine: Patient Notes: Neuropathic pain
Neuropathic pain often seems to have no cause.
With neuropathic pain, the nerve fibers themselves may be damaged or injured.
Interesting research in the field of pain is offering a wide range of new ideas for treatment, and many people can now be helped.
http://www.postgradmed.com/issues/1999/11_99/pn_neuropathy.htm   (676 words)

  
 Central Pain Syndrome Alliance - Welcome
Central Pain Syndrome is a neurological condition, meaning it stays with us, can affect us all differently, in different places on our bodies, and at different levels of pain.
In some cases, when a person rates the pain as a 9 or 10 on a pain scale, and there seems to be no relief in sight, no hope or understanding with support, they may even come to feel that suicide is the only way out.
Neuropathic Pain you may have heard it referred to by any of these names, or perhaps even something else.
http://www.centralpain.org   (634 words)

  
 Pain News & Information - Pain Treatment Updates
, pain relieving medications can increase the frequency of headaches by causing "rebound headaches." Tizanidine is a muscle relaxant with properties that might make it a useful adjunct in the process of withdrawing opioid pain medicines as part of the treatment of rebound headaches.
The effects of epidural blockade on the acute pain in herpes zoster.
Interestingly, suggestions of analgesia can induce alterations of pain perception even in poorly susceptible subjects; however these effects did not occur in the area of the body where the patient was instructed to feel pain relief.
http://www.helpforpain.com/mednews.htm   (4883 words)

  
 Treatment options for neuropathic pain
Because of the complex nature of neuropathic pain, a multi-disciplinary, integrated approach to managing the pain is often useful.
Instead, the primary goals of treatment are to reduce the pain as much as possible, balance the negative side effects of the treatment, and help patients manage any unresolved pain.
Once neuropathic pain is well established, however, it tends to become more difficult to successfully manage and more aggressive treatments may be required.
http://www.spine-health.com/topics/conserv/neuropaintr/neuropaintr01.html   (321 words)

  
 PainOnline.com
The workhorses of pain research, so long hobbled by lack of technology, are proving to be the best guides for the young turks who handle the new machinery.
Is the CNS punishing the muscles in chronic pain?
But the Central Pain is not a choice.
http://www.painonline.com   (961 words)

  
 NeuropathicPainNetwork
Nerve pain is often puzzling and frustrating for people with NeP and physicians, as it seems to respond poorly to standard pain therapies.
The Neuropathic Pain Network (NPN) is a coalition of organizations that exists to actively support people with neuropathic pain, by enabling them to better cope with their pain, to obtain the best treatment and, ultimately, to improve
Neuropathic pain (NeP) is a type of chronic pain caused by injury or disease of the nervous system that frequently results in a burning, tingling and shock-like sensation.
http://www.neuropathicpainnetwork.org   (240 words)

  
 iSTOP Homepage
The Institute for the Study and Treatment of Pain is a non-profit organization dedicated to research, treatment, training and education in chronic pain.
The work of Dr. Chan Gunn has the potential to revolutionize healthcare, and is changing people’s lives everyday.
http://www.istop.org   (55 words)

  
 AVANIR Initiates Phase III Clinical Trial of Neurodex for the Treatment of Diabetic Neuropathic Pain - Forbes.com
The 3-month study will assess the efficacy of Neurodex in relieving pain in adult patients with distal symmetrical diabetic neuropathy with daily pain in the lower extremities.
The degree of pain relief increased with the duration of the open label study.
The clinical trial will be conducted at 40 sites in the United States and will include assessment scales completed in the clinic and diary records to assess pain.
http://www.forbes.com/businesswire/feeds/businesswire/2005/06/23/businesswire20050623005322r1.html   (955 words)

  
 [No title]
In this module, you will review the comprehensive assessment of a patient with neuropathic pain and formulate an initial treatment strategy.
First, you will assess the patient by reviewing the history prior to the present pain complaint and then the history of the present illness.
Throughout this module, health care professionals can 'consult' members of the Department of Pain Medicine and Palliative Care, including physicians, a psychologist, and a social worker.You will need Windows Media Player to view these video clips.
http://www.stoppain.org/for_professionals/interactive_module/elearn.html   (478 words)

  
 StopPain.org
Visit our subpage for professionals in pain medicine and palliative care.
Visit our new pages for consumers and healthcare professionals.
Learn how clinicians manage substance use disorders in patients with chronic pain.
http://www.stoppain.org   (85 words)

  
 USC Pain Center - Pain Treatment News & Information
USC Pain Center - Pain Treatment News & Information
Click for info about the USC Pain Center
The information on this internet site is not intended to be a substitute for professional medical advice.
http://www.helpforpain.com   (112 words)

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