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| | Nelfinavir news articles |
 | | Ongoing protease inhibitor therapy consisted of lopinavir/ritonavir (27.7%), nelfinavir (21%), indinavir (16%), indinavir/ritonavir (8.5%), saquinavir (13... | | | ...were underdosed for 41% of their time on antiretroviral therapy, with the most commonly underdosed drugs being efavirenz (Sustiva) and nelfinavir (Viracept). |
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http://www.mongabay.com/drugs/drugs/Nelfinavir.html
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| | Nelfinavir - Wikipedia, the free encyclopedia |
| | Nelfinavir (Viracept®) is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV). | | | Nelfinavir's interaction profile is similar to that of other protease inhibitors. | | | Nelfinavir is a protease inhibitor: it inhibits HIV-1 and HIV-2 proteases. |
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http://en.wikipedia.org/wiki/Nelfinavir
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| | Nelfinavir/Viracept Product Information -- HIV/AIDS -- AEGIS |
| | Because the potential for HIV cross-resistance between nelfinavir and other protease inhibitors has not been fully explored, it is unknown what effect nelfinavir therapy will have on the activity of coadministered or subsequently administered protease inhibitors. | | | Nelfinavir produced no effects on either male or female mating and fertility or embryo survival in rat studies at exposures comparable to human therapeutic exposure. | | | The clinical relevance of phenotypic and genotypic changes associated with nelfinavir therapy has not been established. |
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http://www.aegis.com/topics/viracept.html
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| | Nelfinavir |
| | Genetic correlates of virological response to an indinavir-containing salvage regimen in patients with nelfinavir failure. | | | Predictors of virological response in HIV-infected patients to salvage antiretroviral therapy that includes nelfinavir. | | | Virologic responses to a ritonavir--saquinavir-containing regimen in patients who had previously failed nelfinavir. |
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http://www.hivresistanceweb.com/protected/drug/nelfinavir.shtml
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| | Case 4: Discussion - Resistance to Nelfinavir - Antiretroviral Rx: Resistance |
| | Nevertheless, because nelfinavir was widely used in previous years and continues to have some current use, important issues remain regarding resistance to nelfinavir and the use of subsequent therapy after development of resistance to nelfinavir. | | | Multiple studies have shown that nelfinavir-based regimens provide good virologic and immunologic responses when used as initial therapy in antiretroviral-naïve patients [1-2]. | | | In the California Collaborative Treatment Group 575 study, investigators performed phenotypic analysis of viral isolates from patients who experienced virologic failure on a protease inhibitor-containing regimen and found that patients failing nelfinavir-based regimens remained more susceptible to other protease inhibitors than did patients failing indinavir-based regimens (Figure 2) [11]. |
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http://depts.washington.edu/hivaids/arvres/case4/discussion.html
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| | NELFINAVIR Faq |
| | Your doctor may prescribe nelfinavir in combination with other drugs which are used to control HIV infection. | | | Nelfinavir does not cure HIV nor does it prevent HIV transmission. | | | It is important to tell your doctor or pharmacist about other drugs you are taking, even those you can buy without a prescription. |
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http://www.tthhivclinic.com/nelfin.htm
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| | nelfinavir Consumer Drug Information |
| | Nelfinavir is not a cure for HIV or AIDS, and the virus can still be transmitted to others during treatment with this medication. | | | Take nelfinavir with a meal to increase the absorption of the drug by the body. | | | Take nelfinavir with a meal to increase absorption of the drug by the body. |
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http://www.drugs.com/mtm/nelfinavir.html
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| | Nelfinavir - Drugs & Vitamins - Drug Library - DrugDigest |
| | Nelfinavir is used in combination with other drugs used to treat the HIV virus. | | | Many medicines may interact with nelfinavir, if you have a question concerning other medicines you may be taking, talk with your pharmacist, prescriber or other health care professional. | | | To help to make sure that your anti-HIV therapy works as well as possible, be very careful to take all of your medicine exactly as prescribed. |
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http://www.drugdigest.org/DD/DVH/Uses/0,3915,480Nelfinavir,00.html
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| | Gastrointestinal Tolerability and Pharmacokinetics (blood levels) of the New 625 mg Nelfinavir Tablets |
| | At the 4th Intl Workshop on Clinical Pharmacology of HIV Therapy (March 27-29, Cannes, France) Roche researchers presented 3 studies exploring the pharmacokinetics (blood levels) & bioequivalence, and the gastrointestinal tolerability of the new nelfinavir 625 mg film-coated tablets in comparison with nelfinavir 250 mg film-coated tablets (Viracept) in healthy subjects and in HIV+ individuals. | | | The authors concluded that patients on 625mg nelfinavir formulation showed improved GI-tolerability over a 4-week period when compared with the 250mg NFV. | | | The authors concluded there were no incidences of moderate or severe diarrhea with either treatment. |
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http://www.natap.org/2003/may/050703_1.htm
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| | Drug Interactions with Nelfinavir |
| | Coadministration of nevirapine and nelfinavir (750 mg three times daily) was studied in 25 HIV+ individuals as part of triple therapy with stavudine. | | | The IC50 for nelfinavir was 2.5 µM. This suggests that there is the potential for clinical drug interactions. | | | Coadministration of nelfinavir (800 mg three times daily) and amprenavir (800 mg three times daily) was studied in 12 HIV+ individuals. |
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http://www.hiv-druginteractions.org/drug/protease/nelinter.htm
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| | NELFINAVIR |
| | It is extremely important that you take nelfinavir and your other antiretroviral medications exactly as directed. | | | Nelfinavir has a number of serious drug interactions. | | | Inform your study clinician if you are taking any of the following medications: |
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http://depts.washington.edu/~actu/drugs/nelfinavir.htm
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| | nelfinavir - HIV: health and medical information about HIV and AIDS |
| | Nevertheless, nelfinavir does not prevent the transmission of HIV among individuals, and it does not cure HIV infections or AIDS. | | | This may result in increased occurrence of myopathy (muscle pain) or rhabdomyolysis (muscle breakdown). | | | Viewers should consult their healthcare provider before combining any drugs with nelfinavir. |
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http://www.medicinenet.com/nelfinavir/article.htm
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| | Aidsmap Nelfinavir and nevirapine well tolerated during pregnancy |
| | There are concerns, however, that the physiological changes associated with pregnancy may change the body’s ability to process anti-HIV therapy. | | | Pregnant women taking nelfinavir were more likely to experience gastrointestinal side-effects than non-pregnant women taking the drug (30% versus 7%, p = 0.001). | | | Pregnant women taking nevirapine were significantly more likely to experience hepatotoxicity than non-pregnant women taking this drug (19% versus 4%, p = 0.003). |
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http://www.aidsmap.com/en/news/15C43682-5A6B-43AF-8FE8-34C3A7D39A9D.asp
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| | Simple Facts Sheets: nelfinavir (Viracept) |
| | The drug rifabutin (Mycobutin) should be avoided if possible when taking nelfinavir. | | | This individual had to stop nelfinavir and use an alternative anti-HIV drug. | | | The antifungal drug ketoconazole (Nizoral) can increase the levels of nelfinavir in the body, but it is not yet known whether this will mean that the dose of the drug will have to be changed. |
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http://www.atdn.org/simple/nelf.html
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| | AIDS Fact Sheet: Nelfinavir (Viracept) |
| | Nelfinavir, also called Viracept?, is a drug used for antiviral therapy. | | | If you want to change how often you take nelfinavir, talk to your doctor. | | | The most common side effects of nelfinavir are diarrhea, weakness, headache, nausea, and abdominal pain. |
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http://www.aids.org/factSheets/444-Nelfinavir-Viracept.html
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| | MedlinePlus Drug Information: Nelfinavir (Systemic) |
| | Liver disease—Effects of nelfinavir may be increased because of slower removal from the body | | | Nelfinavir will not keep you from spreading HIV to other people. | | | When you are taking nelfinavir, it is especially important that your health care professional know if you are taking any of the following: |
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http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/203526.html
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| | Pediatric HIV Drug Fact Sheets: Nelfinavir (NFV) |
| | If your child is taking nelfinavir, be sure to check with your health care provider before stopping this medicine or starting any other prescription or nonprescription medicine. | | | Be sure to tell any other health care provider or clinic that your child is taking nelfinavir. | | | Discuss your questions with your health care provider. |
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http://www.womenchildrenhiv.org/wchiv?page=pi-14-00-13
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| | The Body Pro: Nelfinavir (NFV, Viracept) |
| | Atazanavir Outperforms Nelfinavir at 48 Weeks of Therapy — December 17, 2001 | | | Therapeutic Drug Monitoring of Nelfinavir and Indinavir in Treatment-Naive Patients Improves Therapeutic Outcome After 1 Year: Results From ATHENA — July 9, 2001 | | | Metabolic and Anthropometric Changes Observed in HIV-Infected Patients Treated With Combivir Plus Nelfinavir or Nevirapine (A Substudy of the COMBINE Study) — July 10, 2001 |
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http://www.thebodypro.com/treat/viracept.html
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| | MedlinePlus Drug Information: Nelfinavir |
| | This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. | | | tell your doctor and pharmacist if you are allergic to nelfinavir or any other drugs. | | | Throw away any medication that is outdated or no longer needed. |
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http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a697034.html
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| | Viracept |
| | Pharmacokinetic Evaluation and Short-Term Activity of Stavudine, Nevirapine and Nelfinavir Therapy | | | Monitoring Enhances Response to Viracept (nelfinavir) and Crixivan (indinavir) HIV Treatment | | | Comparison of 4-Drug Regimens and Pairs of Sequential 3-Drug Regimens as Initial Therapy for HIV Infection |
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http://www.hivandhepatitis.com/hiv_and_aids/viracept_1.html
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| | Nelfinavir |
| | nelfinavir - HIV: health and medical information about HIV and AIDS | | | Nelfinavir [ HIV / AIDS Treatment Information ] | | | Our Free Members Enjoy Live Chat, Email, Comments, Forums, Personal Journals, Voting, and Much More! |
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http://fithomepage.freewebpage.org/nelfinavir.htm
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| | HIV7: No Drug-to-Drug Interactions Seen Between Tenofovir and Nelfinavir |
| | International Congress on Drug Therapy in HIV Infection. | | | HIV7: No Drug-to-Drug Interactions Seen Between Tenofovir and Nelfinavir | | | There were no differences with regard to how each drug affected the bioavailability of the other agent, or their peak or nadir levels, Dr. Boffito reported. |
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http://www.docguide.com/dg.nsf/PrintPrint/788F6BFE1053B1BB85256F4F006A9635
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| | Nelfinavir mesylate: a protease inhibitor. |
| | Use of nelfinavir as salvage therapy is also being studied. | | | DATA EXTRACTION: The data on efficacy, pharmacokinetics, adverse effects, and drug interactions were obtained from in vitro studies, as well as open-label and controlled trials. | | | OBJECTIVE: To review the clinical pharmacology, pharmacokinetics, efficacy, adverse effects, drug interactions, and dosage guidelines of nelfinavir mesylate. |
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http://www.aegis.com/aidsline/1999/aug/A9980933.html
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| | Viracept brand nelfinavir: a complete guide from AIDSmeds.com |
| | Ritonavir - nelfinavir combination therapy safe and effective for HIV patients (12/29/00) | | | Active nelfinavir metabolite present in plasma of treated HIV patients (4/9/91) | | | Bone density in HIV patients unaffected by nelfinavir, increased by indinavir (7/26/01) |
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http://www.aidsmeds.com/drugs/Viracept.htm
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| | Nelfinavir |
| | Few studies have investigated PK-PD relationships for nelfinavir. | | | The active metabolite (M8) has often not been taken into account. |
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http://www.fda.gov/ohrms/dockets/ac/00/slides/3621s1d/sld014.htm
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| | Low Nelfinavir Blood levels Causes Treatment failure |
| | Virological failure to highly active antiretroviral therapy has been associated with low drug potency, the selection of drug-resistant variants, poor adherence to medication, or low drug exposuree. | | | Given that the majority of these individuals had undetectable nelfinavir plasma concentrations, a lack of adherence to the medication was the most likely cause of their sub-therapeutic drug levels. | | | Although other causes such as impaired gut absorption or drug interactions could also been involved, the lack of recognition of any nelfinavir trace in our patients strongly suggests that they were not taking the prescribed medication. |
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http://www.natap.org/2003/feb/021103_4.htm
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| | tpan.com - Drug Guide 2005 - Viracept |
| | Companies pit their new drugs against nelfinavir in what amounts to a lame “at least we’re no worse than the weakest one!” trial design. | | | It’s a recommended agent for use in pregnancy and it may get a second life in the world of double PI therapy, so don’t count it out. | | | Regarded as a potency weakling, it’s used like a sparring partner for other PIs in studies. |
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http://www.tpan.com/publications/drug_guide/viracept.html
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| | nelfinavir at MediClickz |
| | Nelfinavir Prescription Drug Information - Buy, Purchase or Order Nelfinavir Online. | | | It is used alone or in combination with other medicines to manage HIV infection... | | | JoltSearch has UK results for nelfinavir and much more! |
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http://www.mediclickz.com/directory/nelfinavir
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| | A Comparison of the Effects of Nevirapine and Nelfinavir on Metabolism and Body Habitus in Antiretroviral-Naive Human ... |
| | A Comparison of the Effects of Nevirapine and Nelfinavir on Metabolism and Body Habitus in Antiretroviral-Naive Human Immunodeficiency Virus-Infected Patients: A Randomized Controlled Study | | | A Comparison of the Effects of Nevirapine and Nelfinavir on Metabolism and Body Habitus in Antiretroviral-Naive Human Immunodeficiency Virus-Infected Patients: A Randomized Controlled Study -- Fisac et al. | | | nelfinavir (NFV) induces a milder lipid profile and morphological |
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http://jcem.endojournals.org/cgi/content/full/88/11/5186
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| | NELFINAVIR MESYLATE (Viracept®) a Commonly Used Medication |
| | Ritonavir increases nelfinavir levels, as does indinavir; indinavir increases nelfinavir levels by 83%. | | | Rifabutin reduces nelfinavir levels by 32%; no dosage adjustment recommendation for nelfinavir has been developed. | | | Dronabinol levels may be higher if given with nelfinavir. |
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http://www.hivdent.org/drugs/NELFINAVIR.htm
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| | Abstract 728 - Pharmacokinetics of Saquinavir (SQV) with Nelfinavir (NFV) or Ritonavir (RTV) in HIV- Infected Children. |
| | Background:Dual protease inhibitor therapy is increasingly accepted either for direct therapeutic effect or as a pharmacokinetic (PK) booster to increase exposure and simplify regimens. | | | Abstract 728 - Pharmacokinetics of Saquinavir (SQV) with Nelfinavir (NFV) or Ritonavir (RTV) in HIV- Infected Children. | | | 728 Pharmacokinetics of Saquinavir (SQV) with Nelfinavir (NFV) or Ritonavir (RTV) in HIV- Infected Children. |
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http://www.retroconference.org/2001/abstracts/abstracts/abstracts/728.htm
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| | The Body: Drug-Drug Interactions |
| | Detailed measurements of drug levels were measured as part of the study. | | | This decrease was not seen among the subjects who took dronabinol or placebo. | | | In a companion presentation (abstract 745), the authors evaluated the pharmacokinetics (drug levels) of either nelfinavir or indinavir. |
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http://www.thebody.com/confs/retro2001/young7.html
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| | WebMD Health - Patient Handout for Wellbutrin Oral |
| | Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: amantadine, diabetes medications (e.g., glipizide, glyburide, insulin), certain HIV drugs (e.g., efavirenz, nelfinavir, ritonavir), levodopa, nicotine products (e.g., patches, gum), regular use of sedatives (e.g., alcohol, alprazolam), stimulants (e.g., amphetamine, cocaine, "ecstasy," ephedrine), warfarin. | | | In some cases a serious, possibly fatal, drug interaction may occur. |
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http://aolsvc.health.webmd.aol.com/drugs/drug-13509-Wellbutrin+Oral.aspx?dru...
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